JP2010533660A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2010533660A5 JP2010533660A5 JP2010516366A JP2010516366A JP2010533660A5 JP 2010533660 A5 JP2010533660 A5 JP 2010533660A5 JP 2010516366 A JP2010516366 A JP 2010516366A JP 2010516366 A JP2010516366 A JP 2010516366A JP 2010533660 A5 JP2010533660 A5 JP 2010533660A5
- Authority
- JP
- Japan
- Prior art keywords
- granulin
- nucleic acid
- pharmaceutical composition
- compound
- protein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 108060003393 Granulin Proteins 0.000 claims 25
- 102000017941 granulin Human genes 0.000 claims 25
- YIEDSISPYKQADU-UHFFFAOYSA-N n-acetyl-n-[2-methyl-4-[(2-methylphenyl)diazenyl]phenyl]acetamide Chemical compound C1=C(C)C(N(C(C)=O)C(=O)C)=CC=C1N=NC1=CC=CC=C1C YIEDSISPYKQADU-UHFFFAOYSA-N 0.000 claims 10
- 150000001875 compounds Chemical class 0.000 claims 8
- 108020004707 nucleic acids Proteins 0.000 claims 8
- 102000039446 nucleic acids Human genes 0.000 claims 8
- 150000007523 nucleic acids Chemical class 0.000 claims 8
- 239000008194 pharmaceutical composition Substances 0.000 claims 8
- 239000003814 drug Substances 0.000 claims 6
- 108090000765 processed proteins & peptides Proteins 0.000 claims 6
- 102000004169 proteins and genes Human genes 0.000 claims 6
- 108090000623 proteins and genes Proteins 0.000 claims 6
- 229940124597 therapeutic agent Drugs 0.000 claims 6
- 230000000069 prophylactic effect Effects 0.000 claims 5
- 102000019204 Progranulins Human genes 0.000 claims 4
- 108010012809 Progranulins Proteins 0.000 claims 4
- 208000004296 neuralgia Diseases 0.000 claims 4
- 208000021722 neuropathic pain Diseases 0.000 claims 4
- 241000124008 Mammalia Species 0.000 claims 2
- 239000012634 fragment Substances 0.000 claims 2
- 244000144972 livestock Species 0.000 claims 2
- 230000002265 prevention Effects 0.000 claims 2
- 230000011664 signaling Effects 0.000 claims 2
- 238000011282 treatment Methods 0.000 claims 2
- 239000004480 active ingredient Substances 0.000 claims 1
- 239000000443 aerosol Substances 0.000 claims 1
- 239000000556 agonist Substances 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 239000008298 dragée Substances 0.000 claims 1
- 239000000839 emulsion Substances 0.000 claims 1
- 239000008187 granular material Substances 0.000 claims 1
- 239000003978 infusion fluid Substances 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 239000006187 pill Substances 0.000 claims 1
- 230000003449 preventive effect Effects 0.000 claims 1
- 238000011321 prophylaxis Methods 0.000 claims 1
- 239000000243 solution Substances 0.000 claims 1
- 239000000725 suspension Substances 0.000 claims 1
- 239000003826 tablet Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102007033359A DE102007033359B4 (de) | 2007-07-16 | 2007-07-16 | Verwendung eines Granulins oder einer Granulin-ähnlichen Verbindung zur Therapie oder Prophylaxe von chronischen Schmerzen |
| DE102007033359.7 | 2007-07-16 | ||
| PCT/DE2008/001138 WO2009010045A1 (de) | 2007-07-16 | 2008-07-14 | Verwendung eines granulins oder einer granulin-ähnlichen verbindung zur therapie oder prophylaxe von chronischen schmerzen |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010533660A JP2010533660A (ja) | 2010-10-28 |
| JP2010533660A5 true JP2010533660A5 (enExample) | 2012-07-05 |
| JP5584618B2 JP5584618B2 (ja) | 2014-09-03 |
Family
ID=40014940
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010516366A Expired - Fee Related JP5584618B2 (ja) | 2007-07-16 | 2008-07-14 | 慢性疼痛の治療又は予防のためのグラニュリン又はグラニュリン様化合物の使用 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US8367616B2 (enExample) |
| EP (1) | EP2178553B1 (enExample) |
| JP (1) | JP5584618B2 (enExample) |
| CA (1) | CA2693141C (enExample) |
| DE (1) | DE102007033359B4 (enExample) |
| WO (1) | WO2009010045A1 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009089635A1 (en) * | 2008-01-16 | 2009-07-23 | Neurodyn, Inc. | Treating neurodegenerative diseases with progranulin (pgrn) |
| US9573972B2 (en) | 2008-10-31 | 2017-02-21 | Neurodyn, Inc. | Nurotoxic sterol glycosides |
| WO2012045451A1 (en) | 2010-10-05 | 2012-04-12 | Ludwig-Maximilians-Universitaet Muenchen | Novel therapeutic treatment of progranulin-dependent diseases |
| US20210284701A1 (en) * | 2016-07-14 | 2021-09-16 | Emory University | Granulin Compositions and Uses Related Thereto |
| MX2022007486A (es) | 2019-12-23 | 2022-06-29 | Denali Therapeutics Inc | Variantes de progranulina. |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1993015195A1 (en) * | 1992-02-03 | 1993-08-05 | Samuel Solomon | Granulins from leukocytes |
| JP2002335972A (ja) * | 2000-06-07 | 2002-11-26 | Ajinomoto Co Inc | インスリン受容体関連受容体結合蛋白質及びその利用 |
| US6872703B2 (en) * | 2000-06-07 | 2005-03-29 | Ajinomoto Co., Inc. | Insulin receptor-related receptor binding protein |
| ES2369695T3 (es) * | 2003-02-26 | 2011-12-05 | A & G PHARMACEUTICAL, INC. | Métodos para incrementar la proliferación de células b. |
| WO2005020902A2 (en) * | 2003-08-21 | 2005-03-10 | Cytokine Pharmasciences, Inc. | Compositions and methods for treating and diagnosing irritable bowel syndrome |
| JP4222614B2 (ja) * | 2005-02-10 | 2009-02-12 | 独立行政法人科学技術振興機構 | 神経因性疼痛治療剤 |
| WO2007000924A1 (ja) * | 2005-06-28 | 2007-01-04 | Osaka University | プログラニュリン活性を抑制または促進する物質を含む医薬組成物、およびプログラニュリン活性を抑制または促進する物質のスクリーニング方法 |
| US8486635B2 (en) * | 2006-05-30 | 2013-07-16 | Mayo Foundation For Medical Education And Research | Detecting and treating dementia |
-
2007
- 2007-07-16 DE DE102007033359A patent/DE102007033359B4/de not_active Expired - Fee Related
-
2008
- 2008-07-14 EP EP08784323.1A patent/EP2178553B1/de not_active Not-in-force
- 2008-07-14 JP JP2010516366A patent/JP5584618B2/ja not_active Expired - Fee Related
- 2008-07-14 WO PCT/DE2008/001138 patent/WO2009010045A1/de not_active Ceased
- 2008-07-14 CA CA2693141A patent/CA2693141C/en not_active Expired - Fee Related
- 2008-07-14 US US12/668,147 patent/US8367616B2/en not_active Expired - Fee Related
-
2012
- 2012-12-28 US US13/729,961 patent/US9655947B2/en not_active Expired - Fee Related
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CA2797437C (en) | Peptides and their use as antimicrobial agents | |
| Chong et al. | The complex interplay between endoplasmic reticulum stress and the NLRP3 inflammasome: a potential therapeutic target for inflammatory disorders | |
| JP2015518818A5 (enExample) | ||
| JP2017508798A (ja) | ヒストンリジン特異的デメチラーゼ（ｌｓｄ１）およびヒストンデアセチラーゼ（ｈｄａｃ）の阻害剤 | |
| JP2010166916A5 (enExample) | ||
| JP2010532761A5 (enExample) | ||
| JP2012529293A5 (enExample) | ||
| KR20150022799A (ko) | 류마티즘 관절염 예방 또는 치료 조성물 | |
| CN102439153A (zh) | 用于刺激哺乳动物对病原体的先天免疫抵抗力的组合物 | |
| JP2010533660A5 (enExample) | ||
| JP2011528895A5 (enExample) | ||
| JP2014513952A5 (enExample) | ||
| JPWO2019156137A5 (enExample) | ||
| Lin et al. | Degradation of misfolded proteins by autophagy: is it a strategy for Huntington's disease treatment? | |
| JP2010533705A5 (enExample) | ||
| EP2855506A1 (en) | Peptide and the use thereof | |
| JP2011528334A5 (enExample) | ||
| JP2013504603A5 (enExample) | ||
| EP3026057A3 (en) | Compositions for prevention and treatment of neurodegenerative diseases | |
| Chatterjee et al. | Immunomodulatory peptides: new therapeutic horizons for emerging and re-emerging infectious diseases | |
| TW200732351A (en) | New cyclic peptide compounds | |
| JP2011508727A5 (enExample) | ||
| JP2007521333A5 (enExample) | ||
| US10688161B2 (en) | Mitrecin a polypeptide with antimicrobial activity | |
| RU2015134356A (ru) | Пептид |