JP2007521333A5 - - Google Patents

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Publication number
JP2007521333A5
JP2007521333A5 JP2006545433A JP2006545433A JP2007521333A5 JP 2007521333 A5 JP2007521333 A5 JP 2007521333A5 JP 2006545433 A JP2006545433 A JP 2006545433A JP 2006545433 A JP2006545433 A JP 2006545433A JP 2007521333 A5 JP2007521333 A5 JP 2007521333A5
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JP
Japan
Prior art keywords
pharmaceutical composition
agonist
composition according
disorder
signaling pathway
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2006545433A
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English (en)
Japanese (ja)
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JP2007521333A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2004/042271 external-priority patent/WO2005061002A2/en
Publication of JP2007521333A publication Critical patent/JP2007521333A/ja
Publication of JP2007521333A5 publication Critical patent/JP2007521333A5/ja
Withdrawn legal-status Critical Current

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JP2006545433A 2003-12-19 2004-12-15 中枢神経系の活動を調節するための組成物および方法 Withdrawn JP2007521333A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US53120103P 2003-12-19 2003-12-19
PCT/US2004/042271 WO2005061002A2 (en) 2003-12-19 2004-12-15 Composition and methods for modulating cns activity

Publications (2)

Publication Number Publication Date
JP2007521333A JP2007521333A (ja) 2007-08-02
JP2007521333A5 true JP2007521333A5 (enExample) 2008-01-17

Family

ID=34710209

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2006545433A Withdrawn JP2007521333A (ja) 2003-12-19 2004-12-15 中枢神経系の活動を調節するための組成物および方法

Country Status (9)

Country Link
US (1) US20050203014A1 (enExample)
EP (1) EP1694353A2 (enExample)
JP (1) JP2007521333A (enExample)
CN (1) CN1917897A (enExample)
AU (1) AU2004305582A1 (enExample)
BR (1) BRPI0417491A (enExample)
CA (1) CA2547338A1 (enExample)
MX (1) MXPA06006659A (enExample)
WO (1) WO2005061002A2 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040224302A1 (en) * 2002-07-16 2004-11-11 Thomas Jessel Systems and methods for screening for modulators of neural differentiation
US7632679B2 (en) * 2002-07-16 2009-12-15 The Trustees Of Columbia University In The City Of New York Systems and methods for screening for modulators of neural differentiation
US7390659B2 (en) 2002-07-16 2008-06-24 The Trustees Of Columbia University In The City Of New York Methods for inducing differentiation of embryonic stem cells and uses thereof
WO2007028770A1 (en) * 2005-09-05 2007-03-15 Neurosearch A/S Monoamine neurotransmitter re-uptake inhibitors for neuroprotection in patients suffering from an advanced stage of a mental disease
JP2009521403A (ja) * 2005-11-14 2009-06-04 ザ・トラスティーズ・オブ・コランビア・ユニバーシティー・イン・ザ・シティー・オブ・ニューヨーク Mriによる神経発生の相関の画像法
WO2008127974A1 (en) * 2007-04-13 2008-10-23 The Trustees Of Columbia University In The City Of New York Stem cell-based culture system for drug development
US8969081B2 (en) * 2008-12-10 2015-03-03 The Trustees Of Columbia University In The City Of New York Caudal motor neuron derived from embryonic stem cells under conditions essentially free of any retinoid
FR2966733B1 (fr) * 2010-10-29 2012-12-14 Centre Nat Rech Scient Nouvelles strategies therapeutiques impliquant la voie de signalisation hedgehog
CN104740633A (zh) * 2013-12-26 2015-07-01 中国科学院上海生命科学研究院 Shh信号通路特异性抑制剂的应用
JP6193176B2 (ja) * 2014-05-12 2017-09-06 ライオン株式会社 活力及び/又は集中力向上剤
CN111551729B (zh) * 2020-04-27 2021-02-09 浙江正熙生物技术股份有限公司 藻红蛋白免疫荧光探针制备方法

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6610656B1 (en) * 1993-12-30 2003-08-26 President And Fellows Of Harvard College Method of promoting chondrocyte differentiation with hedgehog related polypeptides
US5789543A (en) * 1993-12-30 1998-08-04 President And Fellows Of Harvard College Vertebrate embryonic pattern-inducing proteins and uses related thereto
US6261786B1 (en) * 1993-12-30 2001-07-17 Imperial Cancer Res. Technology Screening assays for hedgehog agonists and antagonists
US6165747A (en) * 1993-12-30 2000-12-26 President & Fellows Of Harvard College Nucleic acids encoding hedgehog proteins
US6384192B1 (en) * 1993-12-30 2002-05-07 President & Fellows Of Harvard College Vertebrate embryonic pattern-inducing proteins
EP1616942A3 (en) * 1994-10-07 2006-11-22 The Board Of Trustees Of The Leland Stanford Junior University Patched genes and their use
US6027882A (en) * 1994-10-07 2000-02-22 The Regents Of The University Of California Patched genes and their use for diagnostics
US6429354B1 (en) * 1994-10-07 2002-08-06 The Board Of Trustees Of The Leland Stanford Junior University Patched genes and uses related thereto
US7144997B2 (en) * 1997-07-24 2006-12-05 Curis, Inc. Vertebrate embryonic patterning-inducing proteins, compositions and uses related therto
US6897297B1 (en) * 1997-12-03 2005-05-24 Curis, Inc. Hydrophobically-modified protein compositions and methods
WO2000035948A1 (en) * 1998-12-03 2000-06-22 Biogen, Inc. Methods and compositions for treating disorders involving excitotoxicity
EP1743903A2 (en) * 1998-12-03 2007-01-17 Curis, Inc. Methods and compositions for treating disorders involving excitotoxicity
US20030165897A1 (en) * 1999-12-21 2003-09-04 Burke Richard E. Dispatched polypeptides
US6683192B2 (en) * 2000-03-30 2004-01-27 Curis, Inc. Small organic molecule regulators of cell proliferation
WO2001082946A2 (en) * 2000-04-28 2001-11-08 Curis, Inc. Neuroprotective compositions
JP2004518654A (ja) * 2000-12-21 2004-06-24 ザ マクレーン ホスピタル コーポレーション 鬱病の治療法
US20060078499A1 (en) * 2003-12-01 2006-04-13 Rene Hen Use of hedgehog agonist to treat depression

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