JP2014523871A5 - - Google Patents
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- JP2014523871A5 JP2014523871A5 JP2014514917A JP2014514917A JP2014523871A5 JP 2014523871 A5 JP2014523871 A5 JP 2014523871A5 JP 2014514917 A JP2014514917 A JP 2014514917A JP 2014514917 A JP2014514917 A JP 2014514917A JP 2014523871 A5 JP2014523871 A5 JP 2014523871A5
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- JP
- Japan
- Prior art keywords
- composition
- seq
- functional
- agent
- protein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161495868P | 2011-06-10 | 2011-06-10 | |
| US61/495,868 | 2011-06-10 | ||
| US201261613856P | 2012-03-21 | 2012-03-21 | |
| US61/613,856 | 2012-03-21 | ||
| PCT/US2012/041804 WO2012170977A1 (en) | 2011-06-10 | 2012-06-10 | Modulation of pancreatic beta cell proliferation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2014523871A JP2014523871A (ja) | 2014-09-18 |
| JP2014523871A5 true JP2014523871A5 (enExample) | 2015-06-18 |
Family
ID=47296512
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014514917A Pending JP2014523871A (ja) | 2011-06-10 | 2012-06-10 | 膵臓ベータ細胞増殖の調整 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20140303078A1 (enExample) |
| EP (1) | EP2717924A4 (enExample) |
| JP (1) | JP2014523871A (enExample) |
| CN (1) | CN104039357A (enExample) |
| AU (1) | AU2012267492A1 (enExample) |
| CA (1) | CA2838824A1 (enExample) |
| WO (1) | WO2012170977A1 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20140050720A1 (en) | 2012-01-09 | 2014-02-20 | The Scripps Research Institute | Ultralong complementarity determining regions and uses thereof |
| EP2802601B1 (en) | 2012-01-09 | 2019-11-13 | The Scripps Research Institute | Humanized antibodies with ultralong cdr3s |
| EP2943512A4 (en) * | 2013-01-11 | 2016-06-01 | California Inst Biomedical Res | BOVINE FUSION ANTIBODY |
| CA2904198A1 (en) * | 2013-03-15 | 2014-09-18 | Universite De Geneve | Use of insulin signaling antagonists, optionally in combination of transfection of non-beta cells, for inducing insulin production |
| JP6687520B2 (ja) | 2013-07-18 | 2020-04-22 | トーラス バイオサイエンシズ リミテッド ライアビリティ カンパニー | 極めて長い相補性決定領域を有するヒト化抗体 |
| US9322037B2 (en) * | 2013-09-06 | 2016-04-26 | President And Fellows Of Harvard College | Cas9-FokI fusion proteins and uses thereof |
| CN106536552A (zh) * | 2014-03-12 | 2017-03-22 | 生物控股有限公司 | 能够拮抗胰岛淀粉样多肽(IAPP)诱导的β细胞损伤和葡萄糖耐量受损的新的化合物 |
| CA2954082A1 (en) * | 2014-10-03 | 2016-04-07 | Ngm Biopharmaceuticals, Inc. | Methods and compositions for treatment of conditions associated with elevated triglycerides |
| TW201713690A (zh) * | 2015-08-07 | 2017-04-16 | 再生元醫藥公司 | 抗ａｎｇｐｔｌ８抗體及其用途 |
| WO2017062363A1 (en) * | 2015-10-05 | 2017-04-13 | Joslin Diabetes Center | Methods of use of betatrophin |
| US11161891B2 (en) | 2015-12-09 | 2021-11-02 | The Scripps Research Institute | Relaxin immunoglobulin fusion proteins and methods of use |
| EP3749691A4 (en) | 2017-11-10 | 2021-10-27 | NGM Biopharmaceuticals, Inc. | ANGPTL8 LIAISON AGENTS AND THEIR METHODS OF USE |
| US12508428B2 (en) | 2023-01-26 | 2025-12-30 | Medtronic, Inc. | Respiratory-based cardiac remodeling pacing therapy |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20070055056A1 (en) * | 1997-03-07 | 2007-03-08 | Rosen Craig A | 251 human secreted proteins |
| JP2001512005A (ja) * | 1997-08-01 | 2001-08-21 | ジェンセット | 内胚葉において発現する分泌タンパク質の５’ｅｓｔ |
| US6875741B2 (en) * | 1998-09-02 | 2005-04-05 | Renuka Pillutla | Insulin and IGF-1 receptor agonists and antagonists |
| US20070203083A1 (en) * | 2003-06-13 | 2007-08-30 | Mootha Vamsi K | Methods Of Regulating Metabolism And Mitochondrial Function |
| AU2006223579A1 (en) * | 2005-03-11 | 2006-09-21 | Genentech, Inc. | Gene disruptions, compositions and methods relating thereto |
| JP2009511446A (ja) * | 2005-10-05 | 2009-03-19 | ノボ・ノルデイスク・エー／エス | インスリンレセプターアンタゴニストと、関連した組成物、使用及び方法 |
| CN101130768B (zh) * | 2006-08-22 | 2010-05-12 | 复旦大学 | 核苷酸分子sr1b及其在制备抗糖尿病药物中的应用 |
| NZ575804A (en) * | 2006-09-13 | 2012-01-12 | Univ Columbia | Undercarboxylated/uncarboxylated osteocalcin increases beta-cell proliferation, insulin secretion, insulin sensitivity, glucose tolerance and decreases fat mass |
| US20090232893A1 (en) * | 2007-05-22 | 2009-09-17 | Bader Andreas G | miR-143 REGULATED GENES AND PATHWAYS AS TARGETS FOR THERAPEUTIC INTERVENTION |
-
2012
- 2012-06-10 CN CN201280036842.1A patent/CN104039357A/zh active Pending
- 2012-06-10 WO PCT/US2012/041804 patent/WO2012170977A1/en not_active Ceased
- 2012-06-10 US US14/125,276 patent/US20140303078A1/en not_active Abandoned
- 2012-06-10 JP JP2014514917A patent/JP2014523871A/ja active Pending
- 2012-06-10 EP EP12797387.3A patent/EP2717924A4/en not_active Withdrawn
- 2012-06-10 CA CA2838824A patent/CA2838824A1/en not_active Abandoned
- 2012-06-10 AU AU2012267492A patent/AU2012267492A1/en not_active Abandoned
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