JP2014523871A5 - - Google Patents
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- JP2014523871A5 JP2014523871A5 JP2014514917A JP2014514917A JP2014523871A5 JP 2014523871 A5 JP2014523871 A5 JP 2014523871A5 JP 2014514917 A JP2014514917 A JP 2014514917A JP 2014514917 A JP2014514917 A JP 2014514917A JP 2014523871 A5 JP2014523871 A5 JP 2014523871A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- seq
- functional
- agent
- protein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161495868P | 2011-06-10 | 2011-06-10 | |
| US61/495,868 | 2011-06-10 | ||
| US201261613856P | 2012-03-21 | 2012-03-21 | |
| US61/613,856 | 2012-03-21 | ||
| PCT/US2012/041804 WO2012170977A1 (en) | 2011-06-10 | 2012-06-10 | Modulation of pancreatic beta cell proliferation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2014523871A JP2014523871A (ja) | 2014-09-18 |
| JP2014523871A5 true JP2014523871A5 (enExample) | 2015-06-18 |
Family
ID=47296512
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014514917A Pending JP2014523871A (ja) | 2011-06-10 | 2012-06-10 | 膵臓ベータ細胞増殖の調整 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20140303078A1 (enExample) |
| EP (1) | EP2717924A4 (enExample) |
| JP (1) | JP2014523871A (enExample) |
| CN (1) | CN104039357A (enExample) |
| AU (1) | AU2012267492A1 (enExample) |
| CA (1) | CA2838824A1 (enExample) |
| WO (1) | WO2012170977A1 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013106489A1 (en) | 2012-01-09 | 2013-07-18 | The Scripps Research Institute | Humanized antibodies with ultralong cdr3s |
| US10774132B2 (en) | 2012-01-09 | 2020-09-15 | The Scripps Research Instittue | Ultralong complementarity determining regions and uses thereof |
| CN105073781A (zh) * | 2013-01-11 | 2015-11-18 | 加州生物医学研究所 | 牛融合抗体 |
| US20160067212A1 (en) * | 2013-03-15 | 2016-03-10 | Universite De Geneve | Use of insulin signaling antagonists, optionally in combination of transfection of non-beta cells, for inducing insulin production |
| US10640574B2 (en) | 2013-07-18 | 2020-05-05 | Taurus Biosciences, Llc | Humanized antibodies with ultralong complementary determining regions |
| US9388430B2 (en) * | 2013-09-06 | 2016-07-12 | President And Fellows Of Harvard College | Cas9-recombinase fusion proteins and uses thereof |
| KR102342087B1 (ko) | 2014-03-12 | 2021-12-27 | 뉴리뮨 홀딩 아게 | 섬 아밀로이드 폴리펩티드(iapp) 유도된 베타-세포 부상 및 손상된 글루코오스 내성을 길항할 수 있는 신규한 화합물 |
| EP3822287A1 (en) | 2014-10-03 | 2021-05-19 | NGM Biopharmaceuticals, Inc. | Angptl8 polypeptide and its use for treatment of conditions associated with elevated triglycerides |
| TW201713690A (zh) * | 2015-08-07 | 2017-04-16 | 再生元醫藥公司 | 抗ａｎｇｐｔｌ８抗體及其用途 |
| WO2017062363A1 (en) * | 2015-10-05 | 2017-04-13 | Joslin Diabetes Center | Methods of use of betatrophin |
| PT3387019T (pt) | 2015-12-09 | 2022-01-14 | Scripps Research Inst | Proteínas de fusão de imunoglobulina de relaxina e métodos de uso |
| EP3749691A4 (en) | 2017-11-10 | 2021-10-27 | NGM Biopharmaceuticals, Inc. | ANGPTL8 LIAISON AGENTS AND THEIR METHODS OF USE |
| US12508428B2 (en) | 2023-01-26 | 2025-12-30 | Medtronic, Inc. | Respiratory-based cardiac remodeling pacing therapy |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20070055056A1 (en) * | 1997-03-07 | 2007-03-08 | Rosen Craig A | 251 human secreted proteins |
| CA2296398A1 (en) * | 1997-08-01 | 1999-02-11 | Genset | 5' ests for secreted proteins expressed in endoderm |
| US6875741B2 (en) * | 1998-09-02 | 2005-04-05 | Renuka Pillutla | Insulin and IGF-1 receptor agonists and antagonists |
| US20070203083A1 (en) * | 2003-06-13 | 2007-08-30 | Mootha Vamsi K | Methods Of Regulating Metabolism And Mitochondrial Function |
| EP1863340A2 (en) * | 2005-03-11 | 2007-12-12 | Genentech, Inc. | Gene disruptions, compositions and methods relating thereto |
| CN101321780A (zh) * | 2005-10-05 | 2008-12-10 | 诺沃-诺迪斯克有限公司 | 胰岛素受体拮抗剂及相关组合物、用途和方法 |
| CN101130768B (zh) * | 2006-08-22 | 2010-05-12 | 复旦大学 | 核苷酸分子sr1b及其在制备抗糖尿病药物中的应用 |
| NZ575804A (en) * | 2006-09-13 | 2012-01-12 | Univ Columbia | Undercarboxylated/uncarboxylated osteocalcin increases beta-cell proliferation, insulin secretion, insulin sensitivity, glucose tolerance and decreases fat mass |
| US20090232893A1 (en) * | 2007-05-22 | 2009-09-17 | Bader Andreas G | miR-143 REGULATED GENES AND PATHWAYS AS TARGETS FOR THERAPEUTIC INTERVENTION |
-
2012
- 2012-06-10 CN CN201280036842.1A patent/CN104039357A/zh active Pending
- 2012-06-10 CA CA2838824A patent/CA2838824A1/en not_active Abandoned
- 2012-06-10 WO PCT/US2012/041804 patent/WO2012170977A1/en not_active Ceased
- 2012-06-10 JP JP2014514917A patent/JP2014523871A/ja active Pending
- 2012-06-10 US US14/125,276 patent/US20140303078A1/en not_active Abandoned
- 2012-06-10 EP EP12797387.3A patent/EP2717924A4/en not_active Withdrawn
- 2012-06-10 AU AU2012267492A patent/AU2012267492A1/en not_active Abandoned
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