JP2010531313A5 - - Google Patents

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Publication number
JP2010531313A5
JP2010531313A5 JP2010513710A JP2010513710A JP2010531313A5 JP 2010531313 A5 JP2010531313 A5 JP 2010531313A5 JP 2010513710 A JP2010513710 A JP 2010513710A JP 2010513710 A JP2010513710 A JP 2010513710A JP 2010531313 A5 JP2010531313 A5 JP 2010531313A5
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JP
Japan
Prior art keywords
phenyl
unsubstituted
independently
benzimidazole
methyl
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JP2010513710A
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English (en)
Japanese (ja)
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JP5492770B2 (ja
JP2010531313A (ja
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Priority claimed from PCT/EP2008/004639 external-priority patent/WO2009000413A1/en
Publication of JP2010531313A publication Critical patent/JP2010531313A/ja
Publication of JP2010531313A5 publication Critical patent/JP2010531313A5/ja
Application granted granted Critical
Publication of JP5492770B2 publication Critical patent/JP5492770B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2010513710A 2007-06-26 2008-06-11 ベンゾイミダゾール及びアザベンゾイミダゾールの位置選択的銅触媒合成 Expired - Fee Related JP5492770B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP07290800.7 2007-06-26
EP07290800 2007-06-26
PCT/EP2008/004639 WO2009000413A1 (en) 2007-06-26 2008-06-11 A regioselective copper catalyzed synthesis of benzimidazoles and azabenzimidazoles

Publications (3)

Publication Number Publication Date
JP2010531313A JP2010531313A (ja) 2010-09-24
JP2010531313A5 true JP2010531313A5 (enFirst) 2011-07-07
JP5492770B2 JP5492770B2 (ja) 2014-05-14

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ID=38646504

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010513710A Expired - Fee Related JP5492770B2 (ja) 2007-06-26 2008-06-11 ベンゾイミダゾール及びアザベンゾイミダゾールの位置選択的銅触媒合成

Country Status (12)

Country Link
US (1) US8735586B2 (enFirst)
EP (1) EP2173721B1 (enFirst)
JP (1) JP5492770B2 (enFirst)
KR (1) KR20100023907A (enFirst)
CN (1) CN101687815A (enFirst)
AT (1) ATE539063T1 (enFirst)
AU (1) AU2008267444A1 (enFirst)
BR (1) BRPI0813271A2 (enFirst)
CA (1) CA2691857A1 (enFirst)
IL (1) IL202823A0 (enFirst)
MX (1) MX2009013753A (enFirst)
WO (1) WO2009000413A1 (enFirst)

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CA2785536C (en) 2009-12-30 2018-02-27 Arqule, Inc. Substituted imidazopyridinyl-aminopyridine compounds
US8809541B2 (en) 2010-08-25 2014-08-19 Neopharm Co., Ltd. Heterocyclic compound, and composition for treating inflammatory diseases using same
KR101594002B1 (ko) 2010-10-06 2016-02-15 글락소스미스클라인 엘엘씨 Ｐｉ３ 키나제 억제제로서의 벤즈이미다졸 유도체
CA2831710A1 (en) 2011-03-31 2012-10-04 Bayer Intellectual Property Gmbh Substituted benzimidazoles as mps-1 kinase inhibitors
DK2723741T3 (en) 2011-06-24 2016-06-06 Arqule Inc SUBSTITUTED imidazopyridinyl-aminopyridine compounds
WO2012177852A1 (en) 2011-06-24 2012-12-27 Arqule, Inc Substituted imidazopyridinyl compounds
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US9765039B2 (en) 2012-11-21 2017-09-19 Zenith Epigenetics Ltd. Biaryl derivatives as bromodomain inhibitors
US9073878B2 (en) 2012-11-21 2015-07-07 Zenith Epigenetics Corp. Cyclic amines as bromodomain inhibitors
JP2016507496A (ja) 2012-12-21 2016-03-10 ゼニス・エピジェネティクス・コーポレイションＺｅｎｉｔｈ Ｅｐｉｇｅｎｅｔｉｃｓ Ｃｏｒｐ． ブロモドメイン阻害剤としての新規複素環式化合物
CN103130811B (zh) * 2013-03-11 2015-02-25 河南师范大学 一种5,6-二氢吡唑并[1,5-c]喹唑啉类化合物的合成方法
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US9695149B2 (en) 2013-03-15 2017-07-04 Janssen Pharmaceutica Nv 1,2,6-substituted benzimidazoles as flap modulators
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KR102307566B1 (ko) 2013-06-21 2021-10-05 제니쓰 에피제네틱스 리미티드 신규한 바이사이클릭 브로모도메인 억제제
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CA2919948C (en) 2013-07-31 2020-07-21 Zenith Epigenetics Corp. Novel quinazolinones as bromodomain inhibitors
RU2693484C1 (ru) 2013-11-22 2019-07-03 СиЭль БАЙОСАЕНСИЗ ЭлЭлСи Антагонисты гастрина для лечения и профилактики остеопороза
CN103965136B (zh) * 2014-05-07 2016-09-07 苏州波菲特新材料科技有限公司 一种制备n-甲基噻唑啉-2-酮类化合物的方法
US10179125B2 (en) 2014-12-01 2019-01-15 Zenith Epigenetics Ltd. Substituted pyridines as bromodomain inhibitors
HK1245246A1 (zh) 2014-12-01 2018-08-24 恒翼生物医药科技(上海)有限公司 作为溴域抑制剂的取代吡啶酮
WO2016092375A1 (en) 2014-12-11 2016-06-16 Zenith Epigenetics Corp. Substituted heterocycles as bromodomain inhibitors
CN107406438B (zh) 2014-12-17 2021-05-14 恒翼生物医药科技(上海)有限公司 溴结构域的抑制剂
CN114702495A (zh) 2015-11-20 2022-07-05 福马治疗有限公司 作为泛素-特异性蛋白酶1抑制剂的嘌呤酮
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CN111206260B (zh) * 2020-02-12 2022-03-22 齐鲁工业大学 一种吡啶并[1,2-a]苯并咪唑类化合物的电化学合成方法
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