JP2010529958A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2010529958A5 JP2010529958A5 JP2010510812A JP2010510812A JP2010529958A5 JP 2010529958 A5 JP2010529958 A5 JP 2010529958A5 JP 2010510812 A JP2010510812 A JP 2010510812A JP 2010510812 A JP2010510812 A JP 2010510812A JP 2010529958 A5 JP2010529958 A5 JP 2010529958A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- composition according
- group
- disease
- cells
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000008194 pharmaceutical composition Substances 0.000 claims 10
- 208000015122 neurodegenerative disease Diseases 0.000 claims 9
- 210000004027 cell Anatomy 0.000 claims 7
- 102000040430 polynucleotide Human genes 0.000 claims 5
- 108091033319 polynucleotide Proteins 0.000 claims 5
- 239000002157 polynucleotide Substances 0.000 claims 5
- 229920001184 polypeptide Polymers 0.000 claims 5
- 108090000765 processed proteins & peptides Proteins 0.000 claims 5
- 102000004196 processed proteins & peptides Human genes 0.000 claims 5
- 230000004770 neurodegeneration Effects 0.000 claims 4
- 101710106007 Nucleoredoxin-like protein 2 Proteins 0.000 claims 3
- 241000282414 Homo sapiens Species 0.000 claims 2
- 208000023105 Huntington disease Diseases 0.000 claims 2
- 125000003275 alpha amino acid group Chemical group 0.000 claims 2
- 150000001413 amino acids Chemical class 0.000 claims 2
- 210000004102 animal cell Anatomy 0.000 claims 2
- 210000003169 central nervous system Anatomy 0.000 claims 2
- 239000012634 fragment Substances 0.000 claims 2
- 210000002569 neuron Anatomy 0.000 claims 2
- 108091008695 photoreceptors Proteins 0.000 claims 2
- 239000013598 vector Substances 0.000 claims 2
- 208000024827 Alzheimer disease Diseases 0.000 claims 1
- 241000238631 Hexapoda Species 0.000 claims 1
- 208000018737 Parkinson disease Diseases 0.000 claims 1
- 208000034461 Progressive cone dystrophy Diseases 0.000 claims 1
- 108010029485 Protein Isoforms Proteins 0.000 claims 1
- 102000001708 Protein Isoforms Human genes 0.000 claims 1
- 241000700605 Viruses Species 0.000 claims 1
- 230000001580 bacterial effect Effects 0.000 claims 1
- 239000012472 biological sample Substances 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 201000008615 cone dystrophy Diseases 0.000 claims 1
- 230000007850 degeneration Effects 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 239000013604 expression vector Substances 0.000 claims 1
- 230000002538 fungal effect Effects 0.000 claims 1
- 230000035772 mutation Effects 0.000 claims 1
- 239000002245 particle Substances 0.000 claims 1
- 239000013612 plasmid Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07109652A EP2027889A1 (en) | 2007-06-05 | 2007-06-05 | New neuronal viability factor and use thereof |
| EP07109652.3 | 2007-06-05 | ||
| PCT/EP2008/057031 WO2008148860A1 (en) | 2007-06-05 | 2008-06-05 | New neuronal viability factor and use thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010529958A JP2010529958A (ja) | 2010-09-02 |
| JP2010529958A5 true JP2010529958A5 (enExample) | 2011-07-21 |
| JP5671678B2 JP5671678B2 (ja) | 2015-02-18 |
Family
ID=38573348
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010510812A Active JP5671678B2 (ja) | 2007-06-05 | 2008-06-05 | ニューロン生存因子およびその使用 |
Country Status (5)
| Country | Link |
|---|---|
| US (5) | US9575075B2 (enExample) |
| EP (2) | EP2027889A1 (enExample) |
| JP (1) | JP5671678B2 (enExample) |
| ES (1) | ES2623464T3 (enExample) |
| WO (1) | WO2008148860A1 (enExample) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT1625210E (pt) | 2003-05-21 | 2011-03-15 | Genzyme Corp | Métodos para produzir preparações de vírions de aav recombinantes substancialmente livres de capsídeos vazios |
| EP2027889A1 (en) * | 2007-06-05 | 2009-02-25 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | New neuronal viability factor and use thereof |
| EP2281047B1 (en) | 2008-04-15 | 2020-04-08 | Genzyme Corporation | Methods to produce rod-derived cone viability factor (rdcvf) |
| EP2383286A1 (en) | 2010-04-30 | 2011-11-02 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods and compositions for treatment of retinal degenerative diseases |
| WO2013063383A2 (en) | 2011-10-27 | 2013-05-02 | Wellstat Ophthalmics Corporation | Vectors encoding rod-derived cone viability factor |
| US9265786B1 (en) * | 2012-03-30 | 2016-02-23 | University Of Wyoming | Method for reducing protein misfolding and accumulation in Huntington'S disease cells |
| WO2016185242A1 (en) | 2015-05-21 | 2016-11-24 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Synergistic combination of neuronal viability factors and uses thereof |
| US10946063B2 (en) | 2016-10-11 | 2021-03-16 | Welltat Ophthalmics Corporation | Fusion protein between short form rod-derived cone viability factor and a hydrophilic peptide |
| WO2018134168A1 (en) | 2017-01-17 | 2018-07-26 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods of expressing a polynucleotide of interest in the cone photoreceptors |
| WO2019077159A1 (en) | 2017-10-20 | 2019-04-25 | INSERM (Institut National de la Santé et de la Recherche Médicale) | METHODS OF EXPRESSING POLYNUCLEOTIDE OF INTEREST IN CONE PHOTORECCEPTORS OF A SUBJECT COMPRISING SUB-RETINAL ADMINISTRATION OF A THERAPEUTICALLY EFFECTIVE AMOUNT OF A RECOMBINANT AAV9 DERIVATIVE VECTOR |
| SG11202006796RA (en) | 2017-12-22 | 2020-08-28 | Sparingvision | Constructs comprising neuronal viability factors and uses thereof |
| EP4326339B1 (en) | 2021-04-20 | 2025-04-02 | Institut National de la Santé et de la Recherche Médicale (INSERM) | Compositions and methods for treating retinal degenerative disorders |
| EP4366757A1 (en) * | 2021-07-07 | 2024-05-15 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Synergistic combination of rdcfv2 and rdcvf2l for the treatment of tauopathies |
| AU2023362592A1 (en) | 2022-10-20 | 2025-05-08 | Centre National De La Recherche Scientifique | Compositions and methods for treating retinal degenerative disorders |
| WO2024206928A1 (en) | 2023-03-30 | 2024-10-03 | Pharma Cinq, Llc | VECTOR ENCODING ROD-DERIVED CONE VIABILITY FACTOR AND HUMAN IgK SIGNAL SEQUENCE |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2402563A1 (en) * | 1999-12-23 | 2001-07-26 | Hyseq, Inc. | Novel nucleic acids and polypeptides |
| FR2823221B1 (fr) * | 2001-04-06 | 2004-04-02 | Univ Pasteur | Sequences associees a la degenerescence retinienne et applications |
| FR2870241B1 (fr) * | 2004-05-13 | 2015-02-27 | Novartis Ag | Facteur de viabilite des cones derive des batonnets ou rdcvf et applications |
| US20090011040A1 (en) * | 2007-05-02 | 2009-01-08 | Naash Muna I | Use of compacted nucleic acid nanoparticles in non-viral treatments of ocular diseases |
| EP2027889A1 (en) * | 2007-06-05 | 2009-02-25 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | New neuronal viability factor and use thereof |
| JP5710265B2 (ja) * | 2007-12-06 | 2015-04-30 | アンセルム（アンスチチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル） | 網膜変性疾患の治療のための栄養因子 |
| WO2010029130A1 (en) * | 2008-09-10 | 2010-03-18 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Neuronal viability factor and use thereof |
| WO2013063383A2 (en) * | 2011-10-27 | 2013-05-02 | Wellstat Ophthalmics Corporation | Vectors encoding rod-derived cone viability factor |
| WO2016185242A1 (en) * | 2015-05-21 | 2016-11-24 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Synergistic combination of neuronal viability factors and uses thereof |
| WO2019077159A1 (en) * | 2017-10-20 | 2019-04-25 | INSERM (Institut National de la Santé et de la Recherche Médicale) | METHODS OF EXPRESSING POLYNUCLEOTIDE OF INTEREST IN CONE PHOTORECCEPTORS OF A SUBJECT COMPRISING SUB-RETINAL ADMINISTRATION OF A THERAPEUTICALLY EFFECTIVE AMOUNT OF A RECOMBINANT AAV9 DERIVATIVE VECTOR |
| SG11202006796RA (en) * | 2017-12-22 | 2020-08-28 | Sparingvision | Constructs comprising neuronal viability factors and uses thereof |
-
2007
- 2007-06-05 EP EP07109652A patent/EP2027889A1/en not_active Withdrawn
-
2008
- 2008-06-05 JP JP2010510812A patent/JP5671678B2/ja active Active
- 2008-06-05 WO PCT/EP2008/057031 patent/WO2008148860A1/en not_active Ceased
- 2008-06-05 ES ES08760606.7T patent/ES2623464T3/es active Active
- 2008-06-05 US US12/602,736 patent/US9575075B2/en active Active
- 2008-06-05 EP EP08760606.7A patent/EP2175932B1/en active Active
-
2016
- 2016-07-08 US US15/205,797 patent/US20170014478A1/en not_active Abandoned
-
2018
- 2018-10-02 US US16/149,420 patent/US20190064189A1/en not_active Abandoned
-
2019
- 2019-12-12 US US16/711,492 patent/US11428698B2/en active Active
-
2022
- 2022-07-18 US US17/866,900 patent/US20220404376A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2010529958A5 (enExample) | ||
| Yang et al. | EPAC null mutation impairs learning and social interactions via aberrant regulation of miR-124 and Zif268 translation | |
| Poon et al. | Identification of process-localized mRNAs from cultured rodent hippocampal neurons | |
| Lunn et al. | Spinal muscular atrophy | |
| AU2024201282A1 (en) | Compositions and methods for treating autoimmune diseases and cancers | |
| JP6280222B2 (ja) | サルモネラ菌の非コードｒｎａおよびその同定と使用 | |
| RS64769B1 (sr) | Varijante adeno-asociranih virusa i postupci upotrebe | |
| US20210172017A1 (en) | Methods of in vivo evaluation of gene function | |
| Xu et al. | The soil emergence-related transcription factor PIF3 controls root penetration by interacting with the receptor kinase FER | |
| Wu et al. | Transcriptome analysis of different sizes of 3‐mercaptopropionic acid‐modified cadmium telluride quantum dot‐induced toxic effects reveals immune response in rat hippocampus | |
| CN110760511B (zh) | 一种用于治疗杜氏肌营养不良症的gRNA、表达载体、CRISPR-Cas9系统 | |
| US20220235102A1 (en) | Specific nuclear-anchored independent labeling system | |
| JP2022526297A (ja) | タウ凝集に関連する遺伝的脆弱性を明らかにするためのｃｒｉｓｐｒ／ｃａｓドロップアウトスクリーニングプラットフォーム | |
| WO2006009629A2 (en) | Methods and agents for maintaining muscle mass and for preventing muscle atrophy and biomarkers for monitoring same | |
| Brimacombe et al. | Cloning and embryonic expression patterns of the chicken CELF family | |
| US20250154498A1 (en) | Reagents for subcellular delivery of cargo to target cells | |
| Çakır et al. | De novo transcriptome assembly and comparative analysis elucidate complicated mechanism regulating Astragalus chrysochlorus response to selenium stimuli | |
| CN109134633A (zh) | 抗稻瘟病蛋白和基因、分离的核酸及其应用 | |
| JP2016534752A (ja) | 酸化ストレス、およびｄｎａに対する損傷によって引き起こされる疾患を処置するための、ｇｓｅ２４．２に由来するペプチド | |
| CN115867678A (zh) | 鉴定和表征指环病毒的方法及其用途 | |
| US20240060963A1 (en) | Compositions for detecting secretion and methods of use | |
| CN1914336B (zh) | 犬骨关节炎相关基因及相关的方法和组合物 | |
| CN116376975B (zh) | 激活异染色质基因的方法及应用 | |
| Lu et al. | Strain-specific copy number variation in the intelectin locus on the 129 mouse chromosome 1 | |
| Tian et al. | Comparative genomics provides insights into chromosomal evolution and immunological adaptation in horseshoe bats |