JP2010529958A5 - - Google Patents
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- JP2010529958A5 JP2010529958A5 JP2010510812A JP2010510812A JP2010529958A5 JP 2010529958 A5 JP2010529958 A5 JP 2010529958A5 JP 2010510812 A JP2010510812 A JP 2010510812A JP 2010510812 A JP2010510812 A JP 2010510812A JP 2010529958 A5 JP2010529958 A5 JP 2010529958A5
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- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- composition according
- group
- disease
- cells
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 239000008194 pharmaceutical composition Substances 0.000 claims 10
- 208000015122 neurodegenerative disease Diseases 0.000 claims 9
- 210000004027 cell Anatomy 0.000 claims 7
- 102000040430 polynucleotide Human genes 0.000 claims 5
- 108091033319 polynucleotide Proteins 0.000 claims 5
- 239000002157 polynucleotide Substances 0.000 claims 5
- 229920001184 polypeptide Polymers 0.000 claims 5
- 108090000765 processed proteins & peptides Proteins 0.000 claims 5
- 102000004196 processed proteins & peptides Human genes 0.000 claims 5
- 230000004770 neurodegeneration Effects 0.000 claims 4
- 101710106007 Nucleoredoxin-like protein 2 Proteins 0.000 claims 3
- 241000282414 Homo sapiens Species 0.000 claims 2
- 208000023105 Huntington disease Diseases 0.000 claims 2
- 125000003275 alpha amino acid group Chemical group 0.000 claims 2
- 150000001413 amino acids Chemical class 0.000 claims 2
- 210000004102 animal cell Anatomy 0.000 claims 2
- 210000003169 central nervous system Anatomy 0.000 claims 2
- 239000012634 fragment Substances 0.000 claims 2
- 210000002569 neuron Anatomy 0.000 claims 2
- 108091008695 photoreceptors Proteins 0.000 claims 2
- 239000013598 vector Substances 0.000 claims 2
- 208000024827 Alzheimer disease Diseases 0.000 claims 1
- 241000238631 Hexapoda Species 0.000 claims 1
- 208000018737 Parkinson disease Diseases 0.000 claims 1
- 208000034461 Progressive cone dystrophy Diseases 0.000 claims 1
- 108010029485 Protein Isoforms Proteins 0.000 claims 1
- 102000001708 Protein Isoforms Human genes 0.000 claims 1
- 241000700605 Viruses Species 0.000 claims 1
- 230000001580 bacterial effect Effects 0.000 claims 1
- 239000012472 biological sample Substances 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 201000008615 cone dystrophy Diseases 0.000 claims 1
- 230000007850 degeneration Effects 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 239000013604 expression vector Substances 0.000 claims 1
- 230000002538 fungal effect Effects 0.000 claims 1
- 230000035772 mutation Effects 0.000 claims 1
- 239000002245 particle Substances 0.000 claims 1
- 239000013612 plasmid Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07109652.3 | 2007-06-05 | ||
| EP07109652A EP2027889A1 (en) | 2007-06-05 | 2007-06-05 | New neuronal viability factor and use thereof |
| PCT/EP2008/057031 WO2008148860A1 (en) | 2007-06-05 | 2008-06-05 | New neuronal viability factor and use thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010529958A JP2010529958A (ja) | 2010-09-02 |
| JP2010529958A5 true JP2010529958A5 (enExample) | 2011-07-21 |
| JP5671678B2 JP5671678B2 (ja) | 2015-02-18 |
Family
ID=38573348
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010510812A Active JP5671678B2 (ja) | 2007-06-05 | 2008-06-05 | ニューロン生存因子およびその使用 |
Country Status (5)
| Country | Link |
|---|---|
| US (5) | US9575075B2 (enExample) |
| EP (2) | EP2027889A1 (enExample) |
| JP (1) | JP5671678B2 (enExample) |
| ES (1) | ES2623464T3 (enExample) |
| WO (1) | WO2008148860A1 (enExample) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT2277996E (pt) | 2003-05-21 | 2014-12-16 | Genzyme Corp | Métodos para produzir preparações de vírions de aav recombinantes substancialmente livres de capsídeos vazios |
| EP2027889A1 (en) * | 2007-06-05 | 2009-02-25 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | New neuronal viability factor and use thereof |
| WO2009146183A1 (en) | 2008-04-15 | 2009-12-03 | Genzyme Corporation | Methods to produce rod-derived cone viability factor (rdcvf) |
| EP2383286A1 (en) | 2010-04-30 | 2011-11-02 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods and compositions for treatment of retinal degenerative diseases |
| PL2797613T3 (pl) * | 2011-10-27 | 2020-06-15 | Wellstat Ophthalmics Corporation | Wektory kodujące pręcikowy czynnik żywotności czopków |
| US9265786B1 (en) * | 2012-03-30 | 2016-02-23 | University Of Wyoming | Method for reducing protein misfolding and accumulation in Huntington'S disease cells |
| WO2016185242A1 (en) | 2015-05-21 | 2016-11-24 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Synergistic combination of neuronal viability factors and uses thereof |
| CN109415423A (zh) | 2016-10-11 | 2019-03-01 | 威尔斯达眼科制剂公司 | 短型视杆源性视锥活力因子与亲水性肽的融合蛋白 |
| WO2018134168A1 (en) | 2017-01-17 | 2018-07-26 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods of expressing a polynucleotide of interest in the cone photoreceptors |
| JP7420710B2 (ja) | 2017-10-20 | 2024-01-23 | アンセルム（アンスティチュート・ナシオナル・ドゥ・ラ・サンテ・エ・ドゥ・ラ・ルシェルシュ・メディカル） | 組換えａａｖ９由来ベクターの治療有効量の網膜下送達を含む、対象の錐体視細胞において目的のポリヌクレオチドを発現させる方法 |
| BR112020012471A2 (pt) | 2017-12-22 | 2020-11-24 | Sparingvision | construtos compreendendo fatores de viabilidade neuronal e usos dos mesmos |
| WO2022223644A2 (en) | 2021-04-20 | 2022-10-27 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Compositions and methods for treating retinal degenerative disorders |
| US20250276088A1 (en) * | 2021-07-07 | 2025-09-04 | Institut National de la Santé et de la Recherche Médicale | Synergistic combination of rdcfv2 and rdcvf2l for the treatment of tauopathies |
| JP2025538863A (ja) | 2022-10-20 | 2025-12-02 | スパーリングヴィジョン | 網膜変性疾患を治療するための組成物および方法 |
| US20240342313A1 (en) | 2023-03-30 | 2024-10-17 | Pharma Cinq, Llc | Vector encoding rod-derived cone viability factor and human igk signal sequence |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1242443A4 (en) * | 1999-12-23 | 2005-06-22 | Nuvelo Inc | NEW NUCLEIC ACIDS AND POLYPEPTIDES |
| FR2823221B1 (fr) * | 2001-04-06 | 2004-04-02 | Univ Pasteur | Sequences associees a la degenerescence retinienne et applications |
| FR2870241B1 (fr) * | 2004-05-13 | 2015-02-27 | Novartis Ag | Facteur de viabilite des cones derive des batonnets ou rdcvf et applications |
| US20090011040A1 (en) * | 2007-05-02 | 2009-01-08 | Naash Muna I | Use of compacted nucleic acid nanoparticles in non-viral treatments of ocular diseases |
| EP2027889A1 (en) * | 2007-06-05 | 2009-02-25 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | New neuronal viability factor and use thereof |
| JP5710265B2 (ja) * | 2007-12-06 | 2015-04-30 | アンセルム（アンスチチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル） | 網膜変性疾患の治療のための栄養因子 |
| EP2328917B1 (en) * | 2008-09-10 | 2015-09-02 | INSERM - Institut National de la Santé et de la Recherche Médicale | Neuronal viability factor and use thereof |
| PL2797613T3 (pl) * | 2011-10-27 | 2020-06-15 | Wellstat Ophthalmics Corporation | Wektory kodujące pręcikowy czynnik żywotności czopków |
| WO2016185242A1 (en) * | 2015-05-21 | 2016-11-24 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Synergistic combination of neuronal viability factors and uses thereof |
| JP7420710B2 (ja) * | 2017-10-20 | 2024-01-23 | アンセルム（アンスティチュート・ナシオナル・ドゥ・ラ・サンテ・エ・ドゥ・ラ・ルシェルシュ・メディカル） | 組換えａａｖ９由来ベクターの治療有効量の網膜下送達を含む、対象の錐体視細胞において目的のポリヌクレオチドを発現させる方法 |
| BR112020012471A2 (pt) * | 2017-12-22 | 2020-11-24 | Sparingvision | construtos compreendendo fatores de viabilidade neuronal e usos dos mesmos |
-
2007
- 2007-06-05 EP EP07109652A patent/EP2027889A1/en not_active Withdrawn
-
2008
- 2008-06-05 WO PCT/EP2008/057031 patent/WO2008148860A1/en not_active Ceased
- 2008-06-05 JP JP2010510812A patent/JP5671678B2/ja active Active
- 2008-06-05 ES ES08760606.7T patent/ES2623464T3/es active Active
- 2008-06-05 US US12/602,736 patent/US9575075B2/en active Active
- 2008-06-05 EP EP08760606.7A patent/EP2175932B1/en active Active
-
2016
- 2016-07-08 US US15/205,797 patent/US20170014478A1/en not_active Abandoned
-
2018
- 2018-10-02 US US16/149,420 patent/US20190064189A1/en not_active Abandoned
-
2019
- 2019-12-12 US US16/711,492 patent/US11428698B2/en active Active
-
2022
- 2022-07-18 US US17/866,900 patent/US20220404376A1/en not_active Abandoned
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