JP2010528003A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2010528003A5 JP2010528003A5 JP2010509335A JP2010509335A JP2010528003A5 JP 2010528003 A5 JP2010528003 A5 JP 2010528003A5 JP 2010509335 A JP2010509335 A JP 2010509335A JP 2010509335 A JP2010509335 A JP 2010509335A JP 2010528003 A5 JP2010528003 A5 JP 2010528003A5
- Authority
- JP
- Japan
- Prior art keywords
- foam
- less
- bioactive material
- temperature
- residual moisture
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000006260 foam Substances 0.000 claims 35
- 230000000975 bioactive effect Effects 0.000 claims 14
- 239000000463 material Substances 0.000 claims 14
- 239000000203 mixture Substances 0.000 claims 13
- 238000000034 method Methods 0.000 claims 9
- 238000001035 drying Methods 0.000 claims 8
- 238000009472 formulation Methods 0.000 claims 6
- 241000186779 Listeria monocytogenes Species 0.000 claims 4
- 230000001580 bacterial effect Effects 0.000 claims 4
- 206010022000 influenza Diseases 0.000 claims 4
- 229920000642 polymer Polymers 0.000 claims 4
- 229920005862 polyol Polymers 0.000 claims 4
- 150000003077 polyols Chemical class 0.000 claims 4
- 230000003612 virological effect Effects 0.000 claims 4
- 238000005187 foaming Methods 0.000 claims 3
- 238000004519 manufacturing process Methods 0.000 claims 3
- 239000002904 solvent Substances 0.000 claims 3
- 241000894006 Bacteria Species 0.000 claims 2
- 241000700605 Viruses Species 0.000 claims 2
- 238000007710 freezing Methods 0.000 claims 2
- 230000008014 freezing Effects 0.000 claims 2
- 230000009477 glass transition Effects 0.000 claims 2
- 239000011159 matrix material Substances 0.000 claims 2
- 239000012528 membrane Substances 0.000 claims 2
- 239000000843 powder Substances 0.000 claims 2
- 238000000859 sublimation Methods 0.000 claims 2
- 230000008022 sublimation Effects 0.000 claims 2
- 230000007704 transition Effects 0.000 claims 2
- 241000124008 Mammalia Species 0.000 claims 1
- 230000007613 environmental effect Effects 0.000 claims 1
- 238000004108 freeze drying Methods 0.000 claims 1
- 238000000227 grinding Methods 0.000 claims 1
- 239000007788 liquid Substances 0.000 claims 1
- 239000012669 liquid formulation Substances 0.000 claims 1
- 239000002245 particle Substances 0.000 claims 1
- 230000035899 viability Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US93074607P | 2007-05-18 | 2007-05-18 | |
| US60/930,746 | 2007-05-18 | ||
| PCT/US2008/005840 WO2008143782A1 (en) | 2007-05-18 | 2008-05-06 | Preservation of bioactive materials by freeze dried foam |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013135370A Division JP2013177473A (ja) | 2007-05-18 | 2013-06-27 | 凍結乾燥フォームによる生物活性材料の防腐 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010528003A JP2010528003A (ja) | 2010-08-19 |
| JP2010528003A5 true JP2010528003A5 (https=) | 2011-06-23 |
| JP5307801B2 JP5307801B2 (ja) | 2013-10-02 |
Family
ID=40122017
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010509335A Expired - Fee Related JP5307801B2 (ja) | 2007-05-18 | 2008-05-06 | 凍結乾燥フォームによる生物活性材料の防腐 |
| JP2013135370A Pending JP2013177473A (ja) | 2007-05-18 | 2013-06-27 | 凍結乾燥フォームによる生物活性材料の防腐 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013135370A Pending JP2013177473A (ja) | 2007-05-18 | 2013-06-27 | 凍結乾燥フォームによる生物活性材料の防腐 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US8617576B2 (https=) |
| EP (1) | EP2148923B1 (https=) |
| JP (2) | JP5307801B2 (https=) |
| KR (1) | KR101557169B1 (https=) |
| CN (1) | CN101755044B (https=) |
| BR (1) | BRPI0811161A2 (https=) |
| DK (1) | DK2148923T3 (https=) |
| ES (1) | ES2393160T3 (https=) |
| WO (1) | WO2008143782A1 (https=) |
Families Citing this family (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004096113A2 (en) | 2003-04-28 | 2004-11-11 | Medical Instill Technologies, Inc. | Container with valve assembly for filling and dispensing substances, and apparatus and method for filling |
| WO2007079147A2 (en) | 2005-12-28 | 2007-07-12 | Advanced Bionutrition Corporation | A delivery vehicle for probiotic bacteria comprising a dry matrix of polysaccharides, saccharides and polyols in a glass form and methods of making same |
| US8968721B2 (en) | 2005-12-28 | 2015-03-03 | Advanced Bionutrition Corporation | Delivery vehicle for probiotic bacteria comprising a dry matrix of polysaccharides, saccharides and polyols in a glass form and methods of making same |
| WO2007127286A2 (en) * | 2006-04-24 | 2007-11-08 | Medical Instill Technologies, Inc. | Needle penetrable and laser resealable lyophilization device and related method |
| EP2117354B1 (en) | 2006-12-18 | 2018-08-08 | Advanced BioNutrition Corp. | A dry food product containing live probiotic |
| WO2010111565A2 (en) | 2009-03-27 | 2010-09-30 | Advanced Bionutrition Corporation | Microparticulated vaccines for the oral or nasal vaccination and boostering of animals including fish |
| EP2435554B1 (en) | 2009-05-26 | 2017-07-26 | Advanced Bionutrition Corporation | Stable dry powder composition comprising biologically active microorganisms and/or bioactive materials and methods of making |
| PL2529004T3 (pl) | 2010-01-28 | 2017-12-29 | Advanced Bionutrition Corporation | Sucha szklista kompozycja zawierająca bioaktywny materiał |
| US9504750B2 (en) | 2010-01-28 | 2016-11-29 | Advanced Bionutrition Corporation | Stabilizing composition for biological materials |
| JP2013519723A (ja) | 2010-02-19 | 2013-05-30 | カディラ ファーマシューティカルズ リミテッド | 実質的に保持された免疫原性を有する死細胞の薬学的組成物 |
| WO2012018628A1 (en) | 2010-07-26 | 2012-02-09 | Board Of Regents, The University Of Texas System | Methods for inducing an immune response via buccal and/or sublingual administration of a vaccine |
| AR082682A1 (es) | 2010-08-13 | 2012-12-26 | Advanced Bionutrition Corp | Composicion estabilizadora de almacenamiento en seco para materiales biologicos |
| US20150104868A1 (en) * | 2012-04-22 | 2015-04-16 | Cargill, Inc. | Methods of Maintaining and Improving Biological Cell Function and Activity |
| US20140017318A1 (en) | 2012-07-10 | 2014-01-16 | Kevin O'Connell | Method to produce a medicinal product comprising a biologically active protein and the resulting product |
| US9314519B2 (en) | 2012-08-21 | 2016-04-19 | Intervet Inc. | Liquid stable virus vaccines |
| US20140193456A1 (en) * | 2013-01-09 | 2014-07-10 | Hristem Mitkov Dyanov | Method for Drying-Conservation of Natural Substances |
| US9480739B2 (en) | 2013-03-15 | 2016-11-01 | Intervet Inc. | Bovine virus vaccines that are liquid stable |
| US9393298B2 (en) | 2013-03-15 | 2016-07-19 | Intervet Inc. | Liquid stable bovine virus vaccines |
| AR097762A1 (es) | 2013-09-27 | 2016-04-13 | Intervet Int Bv | Formulaciones secas de vacunas que son estables a temperatura ambiente |
| EP3057612B1 (en) | 2013-10-16 | 2020-05-06 | Merck Sharp & Dohme Corp. | Method of obtaining thermostable dried vaccine formulations |
| WO2015057548A1 (en) | 2013-10-16 | 2015-04-23 | Merck Sharp & Dohme Corp | Thermostable respiratory synctial virus (rsv) vaccine compositions |
| EP3057978B1 (en) | 2013-10-16 | 2022-09-14 | Merck Sharp & Dohme LLC | Method of microwave vacuum drying spherical-shaped pellets of biological materials |
| AR099470A1 (es) | 2014-02-17 | 2016-07-27 | Intervet Int Bv | Vacunas de virus de aves de corral líquidas |
| TWI670085B (zh) | 2014-02-19 | 2019-09-01 | 荷蘭商英特威國際公司 | 液體穩定之豬病毒疫苗 |
| MY194231A (en) | 2015-07-29 | 2022-11-23 | Advanced Bionutrition Corp | Stable dry probiotic compositions for special dietary uses |
| US12558395B2 (en) | 2015-07-29 | 2026-02-24 | Advanced Bionutrition Corp. | Stable dry probiotic compositions for special dietary uses |
| EA039591B1 (ru) | 2015-10-30 | 2022-02-15 | Кабусики Кайся Якулт Хонса | Способ получения осушенных микробных клеток |
| EP3383435A4 (en) | 2015-11-30 | 2019-07-10 | Medimmune, LLC | OPTIMIZED RATES OF AMINO ACIDS AND SUGARS AS AMORPHOUS STABILIZING COMPOUNDS IN PHARMACEUTICAL COMPOSITIONS HAVING HIGH CONCENTRATIONS IN PROTEIN-BASED THERAPEUTICS |
| WO2018081550A1 (en) | 2016-10-28 | 2018-05-03 | Vedanta Biosciences, Inc. | Methods and compositions for preserving bacteria |
| DE112017007639T5 (de) * | 2017-06-13 | 2020-06-04 | Chung Chin SUN | Neues verfahren zum blutplasmaprotein-aktivitätserhalt |
| TWI719220B (zh) * | 2017-06-13 | 2021-02-21 | 英屬維爾京群島商大利緯眾生物科技股份有限公司 | 用於血清蛋白的活性保存的新穎方法 |
| WO2019014338A1 (en) * | 2017-07-11 | 2019-01-17 | Universal Stabilization Technologies, Inc. | METHOD FOR PRESERVING BIOPHARMACEUTICAL PRODUCTS |
| AU2018336988B2 (en) * | 2017-09-19 | 2023-06-22 | Advaxis, Inc. | Compositions and methods for lyophilization of bacteria or Listeria strains |
| WO2019082907A1 (ja) * | 2017-10-27 | 2019-05-02 | クミアイ化学工業株式会社 | 微生物凍結乾燥組成物 |
| KR102646145B1 (ko) * | 2018-05-31 | 2024-03-11 | 주식회사 엑소코바이오 | 줄기세포 유래의 엑소좀을 유효성분으로 포함하는 모공 축소용 조성물 |
| WO2019231134A1 (ko) * | 2018-05-31 | 2019-12-05 | 주식회사 엑소코바이오 | 줄기세포 유래의 엑소좀을 유효성분으로 포함하는 안면 홍조 개선용 조성물 |
| KR102058961B1 (ko) | 2018-07-28 | 2019-12-24 | 주식회사 엑소코바이오 | 엑소좀의 동결건조 방법 |
| KR102163806B1 (ko) | 2018-07-30 | 2020-10-07 | 주식회사 엑소코바이오 | 줄기세포 유래의 엑소좀을 유효성분으로 포함하는 피지분비 감소용 조성물 |
| US11243028B2 (en) * | 2018-12-14 | 2022-02-08 | Fortunata, LLC | Systems and methods of cryo-curing |
| CN111214392B (zh) * | 2020-01-08 | 2021-02-26 | 江苏悦智生物医药有限公司 | 一种球形化妆品冻干泡及其制备方法 |
| EP4168593A4 (en) | 2020-06-23 | 2024-11-27 | The Regents of the University of Colorado, a body corporate | METHODS FOR DIAGNOSIS OF RESPIRATORY PATHOGENS AND PREDICTION OF EVOLUTIONS ASSOCIATED WITH COVID-19 |
| CN116585724A (zh) * | 2023-05-25 | 2023-08-15 | 广州和实生物技术有限公司 | 玻璃化真空干燥试剂及其制备方法 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5766520A (en) * | 1996-07-15 | 1998-06-16 | Universal Preservation Technologies, Inc. | Preservation by foam formation |
| US6468782B1 (en) * | 1996-12-05 | 2002-10-22 | Quadrant Healthcare (Uk) Limited | Methods of preserving prokaryotic cells and compositions obtained thereby |
| US6306345B1 (en) * | 1998-05-06 | 2001-10-23 | Universal Preservation Technologies, Inc. | Industrial scale barrier technology for preservation of sensitive biological materials at ambient temperatures |
| US6423252B1 (en) * | 2000-06-23 | 2002-07-23 | Ethicon, Inc. | Methods of making micropatterned foams |
| CA2467365C (en) * | 2001-12-10 | 2012-11-20 | Bavarian Nordic A/S | Poxvirus containing formulations and process for preparing stable, poxvirus containing compositions |
| WO2003087327A2 (en) * | 2002-04-11 | 2003-10-23 | Medimmune Vaccines, Inc. | Preservation of bioactive materials by freeze dried foam |
| CA2503946C (en) * | 2002-11-01 | 2016-08-16 | Glaxosmithkline Biologicals S.A. | Drying process |
| US7592171B2 (en) * | 2003-02-20 | 2009-09-22 | Centro Nacional De Investigaciones Cientificas (Cnic) | Vibrio cholerae with improved biological safety features in freeze dried form |
| EP1732580A4 (en) | 2003-12-24 | 2008-01-23 | Medimmune Inc | EPHA2 VACCINES |
| EP1937800A4 (en) * | 2005-09-26 | 2009-11-18 | Aeras Global Tb Vaccine Found | METHOD FOR STABILIZING BACTERIAL CELLS |
-
2008
- 2008-05-06 CN CN200880025155.3A patent/CN101755044B/zh not_active Expired - Fee Related
- 2008-05-06 ES ES08767620T patent/ES2393160T3/es active Active
- 2008-05-06 DK DK08767620.1T patent/DK2148923T3/da active
- 2008-05-06 US US12/451,454 patent/US8617576B2/en not_active Expired - Fee Related
- 2008-05-06 JP JP2010509335A patent/JP5307801B2/ja not_active Expired - Fee Related
- 2008-05-06 WO PCT/US2008/005840 patent/WO2008143782A1/en not_active Ceased
- 2008-05-06 BR BRPI0811161-8A2A patent/BRPI0811161A2/pt active Search and Examination
- 2008-05-06 KR KR1020097026374A patent/KR101557169B1/ko not_active Expired - Fee Related
- 2008-05-06 EP EP08767620A patent/EP2148923B1/en not_active Not-in-force
-
2013
- 2013-06-27 JP JP2013135370A patent/JP2013177473A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2010528003A5 (https=) | ||
| KR101863920B1 (ko) | 생물학적 물질용 저장 안정화 건조 조성물 | |
| ES2470340T3 (es) | Vehículo de administración para bacterias probi�ticas que comprende una matriz seca de polisac�ridos, sac�ridos y polioles en forma vítrea | |
| KR101557169B1 (ko) | 냉동 건조 발포체에 의한 생활성 물질의 보존 | |
| NZ601017A (en) | Dry glassy composition comprising a bioactive material | |
| CN102786702B (zh) | 一种控释抗菌膜的制备方法 | |
| AU2011289272A2 (en) | Dry storage stabilizing composition for biological materials | |
| CN102358884B (zh) | 一种两歧双歧杆菌冻干复合保护剂及其应用方法 | |
| CN103599734A (zh) | 一种气凝胶材料及其制备方法 | |
| Wang et al. | Bioinspired cryoprotectants of glucose-based carbon dots | |
| CN102952755A (zh) | 一种保加利亚乳杆菌冻干保护剂及其制备方法 | |
| CN105819440A (zh) | 一种制备块体石墨烯气凝胶的方法 | |
| CN107550628B (zh) | 一种高品质暖贴的制备方法 | |
| CN106148005A (zh) | 一种包埋食品香料趋避赤拟谷盗的微胶囊及其制备方法 | |
| WO2019028976A1 (zh) | 耐热保护剂、猪瘟可室温保存活疫苗及其制备方法和应用 | |
| CN107475119A (zh) | 一种乳酸菌和酵母菌复合发酵剂的保护剂 | |
| Crowe et al. | Stabilization of cells during freeze-drying: the trehalose myth | |
| Xu et al. | Preparation and characteristics of cellulose nanowhisker reinforced acrylic foams synthesized by freeze-casting | |
| CN103040768B (zh) | 一种复方类抗生素的混粉技术 | |
| CN104840433A (zh) | 注射用奥美拉唑钠的冷冻干燥方法及其注射用奥美拉唑钠 | |
| CN110655766A (zh) | 一种用于食品保鲜的聚乳酸多孔膜的制备方法 | |
| CN102585276A (zh) | 一种壳聚糖多孔支架的制备方法 | |
| CN106215186A (zh) | 羊口疮活疫苗耐热保护剂及其冻干粉以及该冻干粉的制备方法 | |
| CN104336574A (zh) | 一种生物-低温冷冻干燥法制备酵母微胶囊的方法 | |
| CN104017316B (zh) | 聚乙烯醇/黄腐植酸季铵盐改性皂石复合材料及其制备方法和制品及其应用 |