JP2010528003A5 - - Google Patents
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- Publication number
- JP2010528003A5 JP2010528003A5 JP2010509335A JP2010509335A JP2010528003A5 JP 2010528003 A5 JP2010528003 A5 JP 2010528003A5 JP 2010509335 A JP2010509335 A JP 2010509335A JP 2010509335 A JP2010509335 A JP 2010509335A JP 2010528003 A5 JP2010528003 A5 JP 2010528003A5
- Authority
- JP
- Japan
- Prior art keywords
- foam
- less
- bioactive material
- temperature
- residual moisture
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000006260 foam Substances 0.000 claims 35
- 230000000975 bioactive effect Effects 0.000 claims 14
- 239000000463 material Substances 0.000 claims 14
- 239000000203 mixture Substances 0.000 claims 13
- 238000000034 method Methods 0.000 claims 9
- 238000001035 drying Methods 0.000 claims 8
- 238000009472 formulation Methods 0.000 claims 6
- 241000186779 Listeria monocytogenes Species 0.000 claims 4
- 230000001580 bacterial effect Effects 0.000 claims 4
- 206010022000 influenza Diseases 0.000 claims 4
- 229920000642 polymer Polymers 0.000 claims 4
- 229920005862 polyol Polymers 0.000 claims 4
- 150000003077 polyols Chemical class 0.000 claims 4
- 230000003612 virological effect Effects 0.000 claims 4
- 238000005187 foaming Methods 0.000 claims 3
- 238000004519 manufacturing process Methods 0.000 claims 3
- 239000002904 solvent Substances 0.000 claims 3
- 241000894006 Bacteria Species 0.000 claims 2
- 241000700605 Viruses Species 0.000 claims 2
- 238000007710 freezing Methods 0.000 claims 2
- 230000008014 freezing Effects 0.000 claims 2
- 230000009477 glass transition Effects 0.000 claims 2
- 239000011159 matrix material Substances 0.000 claims 2
- 239000012528 membrane Substances 0.000 claims 2
- 239000000843 powder Substances 0.000 claims 2
- 238000000859 sublimation Methods 0.000 claims 2
- 230000008022 sublimation Effects 0.000 claims 2
- 230000007704 transition Effects 0.000 claims 2
- 241000124008 Mammalia Species 0.000 claims 1
- 230000007613 environmental effect Effects 0.000 claims 1
- 238000004108 freeze drying Methods 0.000 claims 1
- 238000000227 grinding Methods 0.000 claims 1
- 239000007788 liquid Substances 0.000 claims 1
- 239000012669 liquid formulation Substances 0.000 claims 1
- 239000002245 particle Substances 0.000 claims 1
- 230000035899 viability Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US93074607P | 2007-05-18 | 2007-05-18 | |
| US60/930,746 | 2007-05-18 | ||
| PCT/US2008/005840 WO2008143782A1 (en) | 2007-05-18 | 2008-05-06 | Preservation of bioactive materials by freeze dried foam |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013135370A Division JP2013177473A (ja) | 2007-05-18 | 2013-06-27 | 凍結乾燥フォームによる生物活性材料の防腐 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010528003A JP2010528003A (ja) | 2010-08-19 |
| JP2010528003A5 true JP2010528003A5 (enExample) | 2011-06-23 |
| JP5307801B2 JP5307801B2 (ja) | 2013-10-02 |
Family
ID=40122017
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010509335A Expired - Fee Related JP5307801B2 (ja) | 2007-05-18 | 2008-05-06 | 凍結乾燥フォームによる生物活性材料の防腐 |
| JP2013135370A Pending JP2013177473A (ja) | 2007-05-18 | 2013-06-27 | 凍結乾燥フォームによる生物活性材料の防腐 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013135370A Pending JP2013177473A (ja) | 2007-05-18 | 2013-06-27 | 凍結乾燥フォームによる生物活性材料の防腐 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US8617576B2 (enExample) |
| EP (1) | EP2148923B1 (enExample) |
| JP (2) | JP5307801B2 (enExample) |
| KR (1) | KR101557169B1 (enExample) |
| CN (1) | CN101755044B (enExample) |
| BR (1) | BRPI0811161A2 (enExample) |
| DK (1) | DK2148923T3 (enExample) |
| ES (1) | ES2393160T3 (enExample) |
| WO (1) | WO2008143782A1 (enExample) |
Families Citing this family (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1631496B1 (en) | 2003-04-28 | 2014-02-26 | Medical Instill Technologies, Inc. | Container with valve assembly for filling and dispensing substances, and apparatus and method for filling |
| WO2007079147A2 (en) | 2005-12-28 | 2007-07-12 | Advanced Bionutrition Corporation | A delivery vehicle for probiotic bacteria comprising a dry matrix of polysaccharides, saccharides and polyols in a glass form and methods of making same |
| US8968721B2 (en) | 2005-12-28 | 2015-03-03 | Advanced Bionutrition Corporation | Delivery vehicle for probiotic bacteria comprising a dry matrix of polysaccharides, saccharides and polyols in a glass form and methods of making same |
| WO2007127286A2 (en) | 2006-04-24 | 2007-11-08 | Medical Instill Technologies, Inc. | Needle penetrable and laser resealable lyophilization device and related method |
| JP5285617B2 (ja) | 2006-12-18 | 2013-09-11 | アドバンスド バイオニュートリション コーポレーション | 生きたプロバイオティクスを含む乾燥食物製品 |
| EP3266448B1 (en) | 2009-03-27 | 2022-02-16 | Intervet International B.V. | Microparticulated vaccines for the oral or nasal vaccination and boostering of animals including fish |
| SG176253A1 (en) | 2009-05-26 | 2011-12-29 | Advanced Bionutrition Corp | Stable dry powder composition comprising biologically active microorganisms and/or bioactive materials and methods of making |
| US9504750B2 (en) | 2010-01-28 | 2016-11-29 | Advanced Bionutrition Corporation | Stabilizing composition for biological materials |
| NZ601017A (en) | 2010-01-28 | 2014-07-25 | Advanced Bionutrition Corp | Dry glassy composition comprising a bioactive material |
| CN102753975B (zh) | 2010-02-19 | 2015-05-20 | 卡帝拉药物有限公司 | 基本上保留免疫原性的被杀死细胞的药物组合物 |
| WO2012018628A1 (en) | 2010-07-26 | 2012-02-09 | Board Of Regents, The University Of Texas System | Methods for inducing an immune response via buccal and/or sublingual administration of a vaccine |
| CL2011001984A1 (es) | 2010-08-13 | 2012-06-29 | Advanced Bionutrition Corp | Composicion seca estabilizadora para material biologico que comprende carbohidrato, proteinas hidrolizadas de animal o de planta y un componente de acido carboxilico; metodo de preparacion; y formulacion de entrega oral que comprende la composicion seca estabilizadora. |
| EP2841408A4 (en) * | 2012-04-22 | 2016-06-22 | Cargill Inc | METHODS OF MAINTAINING AND IMPROVING CELL BIOLOGICAL FUNCTION AND ACTIVITY |
| US20140017318A1 (en) * | 2012-07-10 | 2014-01-16 | Kevin O'Connell | Method to produce a medicinal product comprising a biologically active protein and the resulting product |
| US9314519B2 (en) | 2012-08-21 | 2016-04-19 | Intervet Inc. | Liquid stable virus vaccines |
| US20140193456A1 (en) * | 2013-01-09 | 2014-07-10 | Hristem Mitkov Dyanov | Method for Drying-Conservation of Natural Substances |
| US9480739B2 (en) | 2013-03-15 | 2016-11-01 | Intervet Inc. | Bovine virus vaccines that are liquid stable |
| US9393298B2 (en) | 2013-03-15 | 2016-07-19 | Intervet Inc. | Liquid stable bovine virus vaccines |
| AR097762A1 (es) | 2013-09-27 | 2016-04-13 | Intervet Int Bv | Formulaciones secas de vacunas que son estables a temperatura ambiente |
| EP3057978B1 (en) | 2013-10-16 | 2022-09-14 | Merck Sharp & Dohme LLC | Method of microwave vacuum drying spherical-shaped pellets of biological materials |
| WO2015057541A1 (en) | 2013-10-16 | 2015-04-23 | Merck Sharp & Dohme Corp. | Method of obtaining thermostable dried vaccine formulations |
| WO2015057548A1 (en) | 2013-10-16 | 2015-04-23 | Merck Sharp & Dohme Corp | Thermostable respiratory synctial virus (rsv) vaccine compositions |
| AR099470A1 (es) | 2014-02-17 | 2016-07-27 | Intervet Int Bv | Vacunas de virus de aves de corral líquidas |
| TWI670085B (zh) | 2014-02-19 | 2019-09-01 | 荷蘭商英特威國際公司 | 液體穩定之豬病毒疫苗 |
| US12558395B2 (en) | 2015-07-29 | 2026-02-24 | Advanced Bionutrition Corp. | Stable dry probiotic compositions for special dietary uses |
| EP3328215B1 (en) | 2015-07-29 | 2021-07-07 | Advanced BioNutrition Corp. | Stable dry probiotic compositions for special dietary uses |
| WO2017073752A1 (ja) | 2015-10-30 | 2017-05-04 | 株式会社ヤクルト本社 | 微生物乾燥菌体の製造方法 |
| EP3383435A4 (en) | 2015-11-30 | 2019-07-10 | Medimmune, LLC | OPTIMIZED RATES OF AMINO ACIDS AND SUGARS AS AMORPHOUS STABILIZING COMPOUNDS IN PHARMACEUTICAL COMPOSITIONS HAVING HIGH CONCENTRATIONS IN PROTEIN-BASED THERAPEUTICS |
| US11447738B2 (en) * | 2016-10-28 | 2022-09-20 | Vedanta Biosciences, Inc. | Methods and compositions for preserving bacteria |
| TWI719220B (zh) * | 2017-06-13 | 2021-02-21 | 英屬維爾京群島商大利緯眾生物科技股份有限公司 | 用於血清蛋白的活性保存的新穎方法 |
| DE112017007639T5 (de) * | 2017-06-13 | 2020-06-04 | Chung Chin SUN | Neues verfahren zum blutplasmaprotein-aktivitätserhalt |
| JP7198264B2 (ja) * | 2017-07-11 | 2022-12-28 | ユニバーサル スタビリゼイション テクノロジーズ,インコーポレイテッド | バイオ医薬品を保存するための方法 |
| JP7284156B2 (ja) * | 2017-09-19 | 2023-05-30 | アドバクシス, インコーポレイテッド | 細菌またはListeria株の凍結乾燥のための組成物および方法 |
| JP7384347B2 (ja) * | 2017-10-27 | 2023-11-21 | クミアイ化学工業株式会社 | 微生物凍結乾燥組成物 |
| KR102649069B1 (ko) | 2018-05-31 | 2024-03-19 | 주식회사 엑소코바이오 | 줄기세포 유래의 엑소좀을 유효성분으로 포함하는 안면 홍조 개선용 조성물 |
| WO2019231134A1 (ko) * | 2018-05-31 | 2019-12-05 | 주식회사 엑소코바이오 | 줄기세포 유래의 엑소좀을 유효성분으로 포함하는 안면 홍조 개선용 조성물 |
| CN112261871B (zh) | 2018-07-28 | 2022-05-17 | 韩国外泌体生技有限公司 | 用于使外排体冻干的方法 |
| KR102163806B1 (ko) | 2018-07-30 | 2020-10-07 | 주식회사 엑소코바이오 | 줄기세포 유래의 엑소좀을 유효성분으로 포함하는 피지분비 감소용 조성물 |
| US11243028B2 (en) * | 2018-12-14 | 2022-02-08 | Fortunata, LLC | Systems and methods of cryo-curing |
| CN111214392B (zh) * | 2020-01-08 | 2021-02-26 | 江苏悦智生物医药有限公司 | 一种球形化妆品冻干泡及其制备方法 |
| AU2021297245A1 (en) | 2020-06-23 | 2023-02-02 | Illumina Software, Inc. | Methods for diagnosing respiratory pathogens and predicting covid-19 related outcomes |
| CN116585724A (zh) * | 2023-05-25 | 2023-08-15 | 广州和实生物技术有限公司 | 玻璃化真空干燥试剂及其制备方法 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5766520A (en) | 1996-07-15 | 1998-06-16 | Universal Preservation Technologies, Inc. | Preservation by foam formation |
| US6468782B1 (en) * | 1996-12-05 | 2002-10-22 | Quadrant Healthcare (Uk) Limited | Methods of preserving prokaryotic cells and compositions obtained thereby |
| US6306345B1 (en) | 1998-05-06 | 2001-10-23 | Universal Preservation Technologies, Inc. | Industrial scale barrier technology for preservation of sensitive biological materials at ambient temperatures |
| US6423252B1 (en) * | 2000-06-23 | 2002-07-23 | Ethicon, Inc. | Methods of making micropatterned foams |
| US7094412B2 (en) * | 2001-12-10 | 2006-08-22 | Bavarian Nordic A/S | Poxvirus containing formulations and process for preparing stable poxvirus containing compositions |
| EP1494651A4 (en) * | 2002-04-11 | 2010-10-13 | Medimmune Vaccines Inc | PRESERVATION OF BIOACTIVE MATERIALS WITH FREEZZED FOAM |
| CA2503871C (en) * | 2002-11-01 | 2012-12-11 | Glaxosmithkline Biologicals S.A. | An immunogenic composition for generating an immune response against polio virus |
| ES2319527T3 (es) * | 2003-02-20 | 2009-05-08 | Centro Nacional De Investigaciones Cientificas (Cnic) | Cepas atenuadas de vibrio cholerae y vacunas liofilizadas que las contienen. |
| WO2005067460A2 (en) | 2003-12-24 | 2005-07-28 | Medimmune, Inc. | Epha2 vaccines |
| EP1937800A4 (en) | 2005-09-26 | 2009-11-18 | Aeras Global Tb Vaccine Found | METHOD FOR STABILIZING BACTERIAL CELLS |
-
2008
- 2008-05-06 DK DK08767620.1T patent/DK2148923T3/da active
- 2008-05-06 CN CN200880025155.3A patent/CN101755044B/zh not_active Expired - Fee Related
- 2008-05-06 JP JP2010509335A patent/JP5307801B2/ja not_active Expired - Fee Related
- 2008-05-06 ES ES08767620T patent/ES2393160T3/es active Active
- 2008-05-06 EP EP08767620A patent/EP2148923B1/en not_active Not-in-force
- 2008-05-06 WO PCT/US2008/005840 patent/WO2008143782A1/en not_active Ceased
- 2008-05-06 US US12/451,454 patent/US8617576B2/en not_active Expired - Fee Related
- 2008-05-06 KR KR1020097026374A patent/KR101557169B1/ko not_active Expired - Fee Related
- 2008-05-06 BR BRPI0811161-8A2A patent/BRPI0811161A2/pt active Search and Examination
-
2013
- 2013-06-27 JP JP2013135370A patent/JP2013177473A/ja active Pending
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