CN101755044B - 通过冻干泡沫保存生物活性材料 - Google Patents

通过冻干泡沫保存生物活性材料 Download PDF

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Publication number
CN101755044B
CN101755044B CN200880025155.3A CN200880025155A CN101755044B CN 101755044 B CN101755044 B CN 101755044B CN 200880025155 A CN200880025155 A CN 200880025155A CN 101755044 B CN101755044 B CN 101755044B
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China
Prior art keywords
foam
preparation
temperature
active materials
biological active
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Expired - Fee Related
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CN200880025155.3A
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English (en)
Chinese (zh)
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CN101755044A (zh
Inventor
R·韦林
Y·奥
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MedImmune LLC
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MedImmune LLC
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/04—Preserving or maintaining viable microorganisms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/34—Processes using foam culture

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Pulmonology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CN200880025155.3A 2007-05-18 2008-05-06 通过冻干泡沫保存生物活性材料 Expired - Fee Related CN101755044B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US93074607P 2007-05-18 2007-05-18
US60/930,746 2007-05-18
PCT/US2008/005840 WO2008143782A1 (en) 2007-05-18 2008-05-06 Preservation of bioactive materials by freeze dried foam

Publications (2)

Publication Number Publication Date
CN101755044A CN101755044A (zh) 2010-06-23
CN101755044B true CN101755044B (zh) 2014-06-11

Family

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Family Applications (1)

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CN200880025155.3A Expired - Fee Related CN101755044B (zh) 2007-05-18 2008-05-06 通过冻干泡沫保存生物活性材料

Country Status (9)

Country Link
US (1) US8617576B2 (enExample)
EP (1) EP2148923B1 (enExample)
JP (2) JP5307801B2 (enExample)
KR (1) KR101557169B1 (enExample)
CN (1) CN101755044B (enExample)
BR (1) BRPI0811161A2 (enExample)
DK (1) DK2148923T3 (enExample)
ES (1) ES2393160T3 (enExample)
WO (1) WO2008143782A1 (enExample)

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ES2470340T3 (es) 2005-12-28 2014-06-23 Advanced Bionutrition Corporation Vehículo de administración para bacterias probi�ticas que comprende una matriz seca de polisac�ridos, sac�ridos y polioles en forma vítrea
US9222728B2 (en) 2006-04-24 2015-12-29 Medinstill Development Llc Penetrable and resealable lyophilization device
WO2008076975A1 (en) 2006-12-18 2008-06-26 Advanced Bionutrition Corporation A dry food product containing live probiotic
EP3266448B1 (en) 2009-03-27 2022-02-16 Intervet International B.V. Microparticulated vaccines for the oral or nasal vaccination and boostering of animals including fish
AU2010254235B2 (en) 2009-05-26 2015-04-02 Advanced Bionutrition Corporation Stable dry powder composition comprising biologically active microorganisms and/or bioactive materials and methods of making
BR112012018839B1 (pt) 2010-01-28 2020-04-14 Advanced Bionutrition Corp composição vítrea seca compreendendo um material bioativo
US9504750B2 (en) 2010-01-28 2016-11-29 Advanced Bionutrition Corporation Stabilizing composition for biological materials
BR112012020303A2 (pt) 2010-02-19 2019-09-24 Cadila Pharmaceuticals Ltd "composição estável de células mortas com propriedades imunogênicas substancialmente retidas, e, processo e método de preparação da composição."
WO2012018628A1 (en) 2010-07-26 2012-02-09 Board Of Regents, The University Of Texas System Methods for inducing an immune response via buccal and/or sublingual administration of a vaccine
MX350047B (es) 2010-08-13 2017-08-24 Advanced Bionutrition Corp Composicion de estabilizacion de almacenamiento en seco para materiales biologicos.
WO2013163027A1 (en) * 2012-04-22 2013-10-31 Cargill, Incorporated Methods of maintaining and improving biological cell function and activity
US20140017318A1 (en) 2012-07-10 2014-01-16 Kevin O'Connell Method to produce a medicinal product comprising a biologically active protein and the resulting product
US9314519B2 (en) 2012-08-21 2016-04-19 Intervet Inc. Liquid stable virus vaccines
US20140193456A1 (en) * 2013-01-09 2014-07-10 Hristem Mitkov Dyanov Method for Drying-Conservation of Natural Substances
US9480739B2 (en) 2013-03-15 2016-11-01 Intervet Inc. Bovine virus vaccines that are liquid stable
US9393298B2 (en) 2013-03-15 2016-07-19 Intervet Inc. Liquid stable bovine virus vaccines
AR097762A1 (es) 2013-09-27 2016-04-13 Intervet Int Bv Formulaciones secas de vacunas que son estables a temperatura ambiente
US10369213B2 (en) 2013-10-16 2019-08-06 Merck Sharp & Dohme Corp. Thermostable respiratory synctial virus (RSV) vaccine compositions
US10429129B2 (en) 2013-10-16 2019-10-01 Merck Sharp & Dohme Corp. Method of microwave vacuum drying spherical-shaped pellets of biological materials
EP3057612B1 (en) 2013-10-16 2020-05-06 Merck Sharp & Dohme Corp. Method of obtaining thermostable dried vaccine formulations
AR099470A1 (es) 2014-02-17 2016-07-27 Intervet Int Bv Vacunas de virus de aves de corral líquidas
TWI670085B (zh) 2014-02-19 2019-09-01 荷蘭商英特威國際公司 液體穩定之豬病毒疫苗
EP3328215B1 (en) 2015-07-29 2021-07-07 Advanced BioNutrition Corp. Stable dry probiotic compositions for special dietary uses
US12558395B2 (en) 2015-07-29 2026-02-24 Advanced Bionutrition Corp. Stable dry probiotic compositions for special dietary uses
CN108271382A (zh) 2015-10-30 2018-07-10 株式会社益力多本社 微生物干燥菌体的制造方法
EP3383435A4 (en) 2015-11-30 2019-07-10 Medimmune, LLC OPTIMIZED RATES OF AMINO ACIDS AND SUGARS AS AMORPHOUS STABILIZING COMPOUNDS IN PHARMACEUTICAL COMPOSITIONS HAVING HIGH CONCENTRATIONS IN PROTEIN-BASED THERAPEUTICS
CA3041677A1 (en) 2016-10-28 2018-05-03 Vedanta Biosciences, Inc. Methods and compositions for preserving bacteria
WO2018227359A1 (en) * 2017-06-13 2018-12-20 Chung Chin Sun A novel method for blood serum protein activity preservation
TWI719220B (zh) * 2017-06-13 2021-02-21 英屬維爾京群島商大利緯眾生物科技股份有限公司 用於血清蛋白的活性保存的新穎方法
MX421254B (es) * 2017-07-11 2025-02-10 Universal Stabilization Tech Inc Método para la conservación de material biológico.
CN111356760A (zh) * 2017-09-19 2020-06-30 阿德瓦希斯公司 细菌或李斯特菌菌株的冻干组合物和方法
WO2019082907A1 (ja) * 2017-10-27 2019-05-02 クミアイ化学工業株式会社 微生物凍結乾燥組成物
KR102649069B1 (ko) * 2018-05-31 2024-03-19 주식회사 엑소코바이오 줄기세포 유래의 엑소좀을 유효성분으로 포함하는 안면 홍조 개선용 조성물
WO2019231134A1 (ko) * 2018-05-31 2019-12-05 주식회사 엑소코바이오 줄기세포 유래의 엑소좀을 유효성분으로 포함하는 안면 홍조 개선용 조성물
WO2020027466A1 (ko) 2018-07-28 2020-02-06 주식회사 엑소코바이오 엑소좀의 동결건조 방법
KR102163806B1 (ko) 2018-07-30 2020-10-07 주식회사 엑소코바이오 줄기세포 유래의 엑소좀을 유효성분으로 포함하는 피지분비 감소용 조성물
US11243028B2 (en) * 2018-12-14 2022-02-08 Fortunata, LLC Systems and methods of cryo-curing
CN111214392B (zh) * 2020-01-08 2021-02-26 江苏悦智生物医药有限公司 一种球形化妆品冻干泡及其制备方法
CA3184128A1 (en) 2020-06-23 2021-12-30 Kathleen Barnes Methods for diagnosing respiratory pathogens and predicting covid-19 related outcomes
CN116585724A (zh) * 2023-05-25 2023-08-15 广州和实生物技术有限公司 玻璃化真空干燥试剂及其制备方法

Citations (2)

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US6423252B1 (en) * 2000-06-23 2002-07-23 Ethicon, Inc. Methods of making micropatterned foams
US20030219475A1 (en) * 2002-04-11 2003-11-27 Medlmmune Vaccines, Inc. Preservation of bioactive materials by freeze dried foam

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US6468782B1 (en) * 1996-12-05 2002-10-22 Quadrant Healthcare (Uk) Limited Methods of preserving prokaryotic cells and compositions obtained thereby
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Patent Citations (2)

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US6423252B1 (en) * 2000-06-23 2002-07-23 Ethicon, Inc. Methods of making micropatterned foams
US20030219475A1 (en) * 2002-04-11 2003-11-27 Medlmmune Vaccines, Inc. Preservation of bioactive materials by freeze dried foam

Also Published As

Publication number Publication date
JP5307801B2 (ja) 2013-10-02
EP2148923A1 (en) 2010-02-03
US8617576B2 (en) 2013-12-31
WO2008143782A1 (en) 2008-11-27
CN101755044A (zh) 2010-06-23
DK2148923T3 (da) 2012-12-03
KR20100028561A (ko) 2010-03-12
BRPI0811161A2 (pt) 2014-10-07
JP2013177473A (ja) 2013-09-09
US20100297231A1 (en) 2010-11-25
ES2393160T3 (es) 2012-12-19
EP2148923A4 (en) 2010-11-24
EP2148923B1 (en) 2012-08-22
KR101557169B1 (ko) 2015-10-02
JP2010528003A (ja) 2010-08-19

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Granted publication date: 20140611

Termination date: 20170506