JP2010527985A - 急性躁病を治療するための医薬組成物および方法 - Google Patents

急性躁病を治療するための医薬組成物および方法 Download PDF

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Publication number
JP2010527985A
JP2010527985A JP2010508913A JP2010508913A JP2010527985A JP 2010527985 A JP2010527985 A JP 2010527985A JP 2010508913 A JP2010508913 A JP 2010508913A JP 2010508913 A JP2010508913 A JP 2010508913A JP 2010527985 A JP2010527985 A JP 2010527985A
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Japan
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formula
compound
effective amount
therapeutically effective
use according
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JP2010508913A
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Japanese (ja)
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JP2010527985A5 (OSRAM
Inventor
イシュトヴァーン・ラスロヴスキー
ジェルジ・ネーメト
ジェルジ・アンドル
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Richter Gedeon Nyrt
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Richter Gedeon Nyrt
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Publication of JP2010527985A publication Critical patent/JP2010527985A/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965—Non-condensed pyrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

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  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP2010508913A 2007-05-24 2008-05-19 急性躁病を治療するための医薬組成物および方法 Pending JP2010527985A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU0700370A HUP0700370A2 (en) 2007-05-24 2007-05-24 Use of (thio)-carbamoyl-cyclohexane derivatives in the manufacture of a medicament for the treatment of acute mania
PCT/HU2008/000052 WO2008142463A2 (en) 2007-05-24 2008-05-19 Carbamoyl-cyclohexanes for treating acute mania

Publications (2)

Publication Number Publication Date
JP2010527985A true JP2010527985A (ja) 2010-08-19
JP2010527985A5 JP2010527985A5 (OSRAM) 2011-06-30

Family

ID=89987541

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010508913A Pending JP2010527985A (ja) 2007-05-24 2008-05-19 急性躁病を治療するための医薬組成物および方法

Country Status (26)

Country Link
US (1) US20100197704A1 (OSRAM)
EP (1) EP2164572B2 (OSRAM)
JP (1) JP2010527985A (OSRAM)
KR (1) KR20150076266A (OSRAM)
CN (2) CN105193807A (OSRAM)
AU (1) AU2008252621B2 (OSRAM)
CA (1) CA2687528C (OSRAM)
CY (1) CY1113566T1 (OSRAM)
DK (1) DK2164572T4 (OSRAM)
EA (1) EA021936B1 (OSRAM)
ES (1) ES2397962T5 (OSRAM)
GE (1) GEP20135731B (OSRAM)
HR (1) HRP20130092T4 (OSRAM)
HU (1) HUP0700370A2 (OSRAM)
IL (1) IL202048A (OSRAM)
MX (1) MX2009012752A (OSRAM)
MY (1) MY148955A (OSRAM)
NZ (1) NZ582284A (OSRAM)
PL (1) PL2164572T5 (OSRAM)
PT (1) PT2164572E (OSRAM)
RS (1) RS52613B2 (OSRAM)
SI (1) SI2164572T2 (OSRAM)
TW (1) TWI428130B (OSRAM)
UA (1) UA101323C2 (OSRAM)
WO (1) WO2008142463A2 (OSRAM)
ZA (1) ZA200908283B (OSRAM)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUP0700353A2 (en) * 2007-05-18 2008-12-29 Richter Gedeon Nyrt Metabolites of (thio)carbamoyl-cyclohexane derivatives
US7875610B2 (en) * 2007-12-03 2011-01-25 Richter Gedeon Nyrt. Pyrimidinyl-piperazines useful as D3/D2 receptor ligands
EP2251011B1 (en) * 2008-02-21 2012-04-04 Richter Gedeon Nyrt. Solid preparation for oral administration
SI2317852T1 (sl) 2008-07-16 2015-04-30 Richter Gedeon Nyrt. Farmacevtske formulacije, ki vsebujejo ligande dopaminskega receptorja
HU230067B1 (hu) 2008-12-17 2015-06-29 Richter Gedeon Nyrt Új piperazin só és eljárás előállítására
HUP0800766A2 (en) 2008-12-18 2010-11-29 Richter Gedeon Vegyeszet Process for the preparation of piperazine derivatives
HUP0800765A2 (en) 2008-12-18 2010-11-29 Richter Gedeon Nyrt A new process for the preparation of piperazine derivatives and their hydrochloric salts
US9610274B2 (en) * 2010-06-30 2017-04-04 Sk Biopharmaceuticals Co., Ltd. Methods for treating bipolar disorder
US8912197B2 (en) 2012-08-20 2014-12-16 Forest Laboratories Holdings Ltd. Crystalline form of carbamoyl-cyclohexane derivatives
US11274087B2 (en) 2016-07-08 2022-03-15 Richter Gedeon Nyrt. Industrial process for the preparation of cariprazine
US11547707B2 (en) 2019-04-10 2023-01-10 Richter Gedeon Nyrt. Carbamoyl cyclohexane derivatives for treating autism spectrum disorder

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007501215A (ja) * 2003-08-04 2007-01-25 リヒター ゲデオン ベジェセティ ジャール アールテー． Ｄ３／ｄ２受容体アンタゴニストとしての（チオ）カルバモイル−シクロヘキサン誘導体
JP2010526832A (ja) * 2007-05-11 2010-08-05 リヒター ゲデオン エヌワイアールティー． カルバモイル−シクロヘキサン誘導体の溶媒和物および結晶形態

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RS50680B (sr) * 2001-02-27 2010-06-30 Ortho-Mcneil Pharmaceutical Inc. Karbamatna jedinjenja za upotrebu u sprečavanju i lečenju bipolarnih poremećaja

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007501215A (ja) * 2003-08-04 2007-01-25 リヒター ゲデオン ベジェセティ ジャール アールテー． Ｄ３／ｄ２受容体アンタゴニストとしての（チオ）カルバモイル−シクロヘキサン誘導体
JP2010526832A (ja) * 2007-05-11 2010-08-05 リヒター ゲデオン エヌワイアールティー． カルバモイル−シクロヘキサン誘導体の溶媒和物および結晶形態

Also Published As

Publication number Publication date
DK2164572T3 (da) 2013-02-11
GEP20135731B (en) 2013-01-25
UA101323C2 (en) 2013-03-25
AU2008252621B2 (en) 2013-09-19
EA200971087A1 (ru) 2010-04-30
ZA200908283B (en) 2010-08-25
MX2009012752A (es) 2010-03-15
AU2008252621A1 (en) 2008-11-27
ES2397962T3 (es) 2013-03-12
CA2687528C (en) 2016-07-05
EP2164572B2 (en) 2015-09-16
HRP20130092T1 (en) 2013-02-28
NZ582284A (en) 2012-07-27
PL2164572T5 (pl) 2016-02-29
IL202048A (en) 2014-11-30
RS52613B (en) 2013-04-30
IL202048A0 (en) 2010-06-16
HK1136984A1 (en) 2010-07-16
WO2008142463A3 (en) 2009-03-05
WO2008142463A2 (en) 2008-11-27
CA2687528A1 (en) 2008-11-27
CY1113566T1 (el) 2016-06-22
SI2164572T2 (sl) 2016-01-29
PL2164572T3 (pl) 2013-04-30
US20100197704A1 (en) 2010-08-05
RS52613B2 (sr) 2018-05-31
DK2164572T4 (en) 2016-01-04
HU0700370D0 (en) 2007-07-30
CN101678212A (zh) 2010-03-24
CN105193807A (zh) 2015-12-30
TW201002326A (en) 2010-01-16
HUP0700370A2 (en) 2009-04-28
HRP20130092T4 (hr) 2016-01-01
KR20150076266A (ko) 2015-07-06
MY148955A (en) 2013-06-14
TWI428130B (zh) 2014-03-01
SI2164572T1 (sl) 2013-02-28
EP2164572A2 (en) 2010-03-24
PT2164572E (pt) 2013-01-28
EP2164572B1 (en) 2012-11-14
ES2397962T5 (es) 2016-01-08
EA021936B1 (ru) 2015-10-30

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