JP2010527980A5 - - Google Patents

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Publication number
JP2010527980A5
JP2010527980A5 JP2010508908A JP2010508908A JP2010527980A5 JP 2010527980 A5 JP2010527980 A5 JP 2010527980A5 JP 2010508908 A JP2010508908 A JP 2010508908A JP 2010508908 A JP2010508908 A JP 2010508908A JP 2010527980 A5 JP2010527980 A5 JP 2010527980A5
Authority
JP
Japan
Prior art keywords
alkyl
aryl
acceptable salt
pharmaceutically acceptable
cycloalkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2010508908A
Other languages
English (en)
Japanese (ja)
Other versions
JP2010527980A (ja
Filing date
Publication date
Priority claimed from GB0709789A external-priority patent/GB0709789D0/en
Priority claimed from GB0800454A external-priority patent/GB0800454D0/en
Application filed filed Critical
Priority claimed from PCT/GB2008/050370 external-priority patent/WO2008142454A1/en
Publication of JP2010527980A publication Critical patent/JP2010527980A/ja
Publication of JP2010527980A5 publication Critical patent/JP2010527980A5/ja
Pending legal-status Critical Current

Links

JP2010508908A 2007-05-22 2008-05-22 代謝障害を治療するための二環状アリールおよびヘテロアリール化合物 Pending JP2010527980A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0709789A GB0709789D0 (en) 2007-05-22 2007-05-22 Compounds
GB0800454A GB0800454D0 (en) 2008-01-11 2008-01-11 Compounds
PCT/GB2008/050370 WO2008142454A1 (en) 2007-05-22 2008-05-22 Bicyclic aryl and heteroaryl compounds for the treatment of metabolic disorders

Publications (2)

Publication Number Publication Date
JP2010527980A JP2010527980A (ja) 2010-08-19
JP2010527980A5 true JP2010527980A5 (enExample) 2011-07-07

Family

ID=39643985

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010508908A Pending JP2010527980A (ja) 2007-05-22 2008-05-22 代謝障害を治療するための二環状アリールおよびヘテロアリール化合物

Country Status (4)

Country Link
US (1) US8278442B2 (enExample)
EP (1) EP2152671A1 (enExample)
JP (1) JP2010527980A (enExample)
WO (1) WO2008142454A1 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008142454A1 (en) 2007-05-22 2008-11-27 Prosidion Limited Bicyclic aryl and heteroaryl compounds for the treatment of metabolic disorders
EP2197835A1 (en) * 2007-09-07 2010-06-23 Prosidion Limited Bicyclic aryl and heteroaryl receptor modulators
WO2012090177A2 (en) * 2010-12-30 2012-07-05 Lupin Limited Cannabinoid receptor modulators
IN2014MN00226A (enExample) * 2011-07-05 2015-09-25 Lupin Ltd
US10273234B2 (en) * 2012-08-06 2019-04-30 Biogen Ma Inc. Compounds that are S1P modulating agents and/or ATX modulating agents
KR102305244B1 (ko) 2013-11-20 2021-09-27 우베 고산 가부시키가이샤 신규 3-아자비사이클로[3.1.0]헥산 유도체 및 그 의약 용도
MX2016016488A (es) * 2014-08-27 2017-03-30 Hoffmann La Roche Derivados de azetidina sustituidos como ligandos de receptores asociados a aminas en trazas (taar).
CA2985710C (en) * 2015-05-20 2023-07-25 Integrative Research Laboratories Sweden Ab Novel azetidine derivatives useful as modulators of cortical cathecolaminergic neurotransmission
CN105330616B (zh) * 2015-12-09 2017-09-26 苏州明锐医药科技有限公司 卡利拉嗪的制备方法
CN110035745B (zh) * 2016-10-05 2022-04-29 匹兹堡大学联邦系统高等教育 小分子ampk活化剂
CN106588842A (zh) * 2016-12-05 2017-04-26 天津羲泽润科技有限公司 一种合成7‑甲氧基‑1‑苯并呋喃‑4‑甲醛的方法
AU2020345766A1 (en) 2019-09-10 2022-03-03 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Methods and materials for increasing level of phosphorylated AMPK protein
US20250179052A1 (en) * 2022-03-01 2025-06-05 Syngenta Crop Protection Ag Pyrimidinyl-oxy-quinoline based herbicidal compounds

Family Cites Families (21)

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Publication number Priority date Publication date Assignee Title
US6225080B1 (en) 1992-03-23 2001-05-01 George R. Uhl Mu-subtype opioid receptor
US6235496B1 (en) 1993-03-08 2001-05-22 Advanced Research & Technology Institute Nucleic acid encoding mammalian mu opioid receptor
US5658783A (en) 1993-11-08 1997-08-19 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education On Behalf Of The Oregon Health Sciences University, A Non-Profit Organization Mammalian methadone-specific opioid receptor gene and uses
US5821219A (en) 1995-08-11 1998-10-13 Oregon Health Sciences University Opioid antagonists and methods of their use
EP1513813B1 (en) 2002-05-30 2005-11-02 Eli Lilly And Company Opioid receptor antagonists
MY140236A (en) 2002-09-19 2009-12-31 Lilly Co Eli Diarylether compounds useful as opioid receptor antagonists
ES2294475T3 (es) * 2003-03-07 2008-04-01 Eli Lilly And Company Derivados de nicotinamida g-sustituidos como antagonistas de receptores de opioides.
CN1753884A (zh) 2003-03-07 2006-03-29 伊莱利利公司 阿片类受体拮抗剂
CA2549009A1 (en) 2003-12-12 2005-07-07 Eli Lilly And Company Opioid receptor antagonists
US7414132B2 (en) 2003-12-22 2008-08-19 Eli Lilly And Company Opioid receptor antagonists
EP1730140B1 (en) 2004-03-12 2008-06-25 Eli Lilly And Company Opioid receptor antagonists
EP1727788B1 (en) 2004-03-12 2010-07-28 Eli Lilly And Company Opioid receptor antagonists
ES2379362T3 (es) 2004-03-15 2012-04-25 Eli Lilly And Company Antagonistas del receptor opioide
DE602005012380D1 (de) 2004-03-15 2009-03-05 Lilly Co Eli 4-(5-(aminomethyl)-indol-1-ylmethyl)benzamidderivate und verwandte verbindungen als opioidrezeptorantagonisten zur behandlung von fettleibigkeit
US7939528B2 (en) 2005-10-13 2011-05-10 Glaxosmithkline Llc Heterocycle compounds
US20100222345A1 (en) 2006-08-09 2010-09-02 Caroline Jean Diaz Novel compounds as antagonists or inverse agonists for opioid receptors
CN102516115B (zh) 2006-08-09 2016-05-11 史密丝克莱恩比彻姆公司 作为阿片样物质受体的拮抗剂或反向激动剂的新型化合物
AU2007297285A1 (en) 2006-09-08 2008-03-20 Pfizer Products Inc. Diaryl ether derivatives and uses thereof
CA2669311C (en) 2006-11-13 2011-09-20 Pfizer Products Inc. Diaryl, dipyridinyl and aryl-pyridinyl derivatives and uses thereof
WO2008142454A1 (en) 2007-05-22 2008-11-27 Prosidion Limited Bicyclic aryl and heteroaryl compounds for the treatment of metabolic disorders
US20100113512A1 (en) 2008-10-30 2010-05-06 Diane Michele Ignar Method of treatment using novel antagonists or inverse agonists at opioid receptors

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