JP2010526840A5 - - Google Patents

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Publication number
JP2010526840A5
JP2010526840A5 JP2010507811A JP2010507811A JP2010526840A5 JP 2010526840 A5 JP2010526840 A5 JP 2010526840A5 JP 2010507811 A JP2010507811 A JP 2010507811A JP 2010507811 A JP2010507811 A JP 2010507811A JP 2010526840 A5 JP2010526840 A5 JP 2010526840A5
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JP
Japan
Prior art keywords
proportions
mixtures
compound according
treatment
pharmaceutically usable
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JP2010507811A
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English (en)
Japanese (ja)
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JP5543335B2 (ja
JP2010526840A (ja
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Priority claimed from DE102007022565A external-priority patent/DE102007022565A1/de
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Publication of JP2010526840A publication Critical patent/JP2010526840A/ja
Publication of JP2010526840A5 publication Critical patent/JP2010526840A5/ja
Application granted granted Critical
Publication of JP5543335B2 publication Critical patent/JP5543335B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2010507811A 2007-05-14 2008-04-18 複素環式インダゾール誘導体 Expired - Fee Related JP5543335B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102007022565.4 2007-05-14
DE102007022565A DE102007022565A1 (de) 2007-05-14 2007-05-14 Heterocyclische Indazolderivate
PCT/EP2008/003143 WO2008138448A2 (de) 2007-05-14 2008-04-18 Heterocyclische indazolderivate

Publications (3)

Publication Number Publication Date
JP2010526840A JP2010526840A (ja) 2010-08-05
JP2010526840A5 true JP2010526840A5 (enExample) 2011-06-02
JP5543335B2 JP5543335B2 (ja) 2014-07-09

Family

ID=39837777

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010507811A Expired - Fee Related JP5543335B2 (ja) 2007-05-14 2008-04-18 複素環式インダゾール誘導体

Country Status (10)

Country Link
US (1) US8334309B2 (enExample)
EP (1) EP2155728B1 (enExample)
JP (1) JP5543335B2 (enExample)
AR (1) AR066557A1 (enExample)
AU (1) AU2008250706B2 (enExample)
CA (1) CA2687162C (enExample)
DE (1) DE102007022565A1 (enExample)
ES (1) ES2548444T3 (enExample)
IL (1) IL202034A (enExample)
WO (1) WO2008138448A2 (enExample)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011107494A1 (de) 2010-03-03 2011-09-09 Sanofi Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung
US8530413B2 (en) 2010-06-21 2013-09-10 Sanofi Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments
TW201221505A (en) 2010-07-05 2012-06-01 Sanofi Sa Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament
TW201215387A (en) 2010-07-05 2012-04-16 Sanofi Aventis Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament
TW201215388A (en) 2010-07-05 2012-04-16 Sanofi Sa (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments
WO2012135631A1 (en) 2011-03-30 2012-10-04 Arrien Pharmaeuticals Llc Substituted 5-(pyrazin-2-yl)-1h-pyrazolo [3, 4-b] pyridine and pyrazolo [3, 4-b] pyridine derivatives as protein kinase inhibitors
WO2012173099A1 (ja) * 2011-06-14 2012-12-20 塩野義製薬株式会社 血管内皮リパーゼ阻害活性を有するアミノ誘導体
WO2013037390A1 (en) 2011-09-12 2013-03-21 Sanofi 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
EP2567959B1 (en) 2011-09-12 2014-04-16 Sanofi 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
EP2760862B1 (en) 2011-09-27 2015-10-21 Sanofi 6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
AU2014293013A1 (en) 2013-07-26 2016-03-17 Race Oncology Ltd. Combinatorial methods to improve the therapeutic benefit of bisantrene
JP2018506571A (ja) 2015-02-27 2018-03-08 リセラ・コーポレイションＬｙｃｅｒａ Ｃｏｒｐｏｒａｔｉｏｎ Ｒｈｏ関連プロテインキナーゼの阻害及び疾患の治療のためのインダゾリルチアジアゾールアミン及び関連する化合物
EP3504204A4 (en) 2016-08-26 2020-05-27 Lycera Corporation INDAZOLYL-L, 2,4-THIADIAZOLAMINE AND RELATED COMPOUNDS FOR INHIBITING RHO-ASSOCIATED PROTEIN KINASES AND FOR TREATING DISEASES
GB201801226D0 (en) 2018-01-25 2018-03-14 Redx Pharma Plc Modulators of Rho-associated protein kinase
JP2022547882A (ja) * 2019-09-06 2022-11-16 インフレイゾーム リミテッド Ｎｌｒｐ３阻害剤
CN111548320B (zh) * 2019-10-09 2023-03-24 贵州大学 一类1，3，4-噁二唑酰肼类化合物及其制备方法和应用
GB202200735D0 (en) * 2022-01-20 2022-03-09 Redx Pharma Plc Compounds

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ227841A (en) 1988-02-12 1991-08-27 Merck Sharp & Dohme Heterocyclic compounds with at least two non-condensed five membered rings and pharmaceutical compositions
DE19917990A1 (de) 1999-04-20 2000-11-02 Florian Lang Arzneimittel enthaltend Hemmstoffe der zellvolumenregulierten humanen Kinase h-sgk
US6897231B2 (en) 2000-07-31 2005-05-24 Signal Pharmaceuticals, Inc. Indazole derivatives as JNK inhibitors and compositions and methods related thereto
DE10042137A1 (de) 2000-08-28 2002-03-14 Florian Lang sgk2 und sgk3 als diagnostische und therapeutische Targets
US7115617B2 (en) * 2001-08-22 2006-10-03 Amgen Inc. Amino-substituted pyrimidinyl derivatives and methods of use
AU2002353186A1 (en) 2001-12-19 2003-06-30 Smithkline Beecham P.L.C. (1-h-indazol-3-yl) -amide derivatives as gsk-3 inhibitors
TW200306819A (en) 2002-01-25 2003-12-01 Vertex Pharma Indazole compounds useful as protein kinase inhibitors
FR2836915B1 (fr) * 2002-03-11 2008-01-11 Aventis Pharma Sa Derives d'aminoindazoles, procede de preparation et intermediaires de ce procede a titre de medicaments et compositions pharmaceutiques les renfermant
WO2003097610A1 (en) 2002-05-17 2003-11-27 Pharmacia Italia S.P.A. Aminoindazole derivatives active as kinase inhibitors, process for their preparation and pharmaceutical compositions comprising them
PL374946A1 (en) 2002-09-05 2005-11-14 Aventis Pharma S.A. Novel aminoindazole derivatives as medicines and pharmaceutical compositions containing same
FR2844267B1 (fr) 2002-09-05 2008-02-15 Aventis Pharma Sa Nouveaux derives d'aminoindazoles a titre de medicaments et compositions pharmaceutiques les renfermant
AU2003293376A1 (en) 2002-12-10 2004-06-30 Imclone Systems Incorporated Anti-angiogenic compounds and their use in cancer treatment
FR2848554A1 (fr) 2002-12-12 2004-06-18 Aventis Pharma Sa Nouveaux derives d'aminoindazoles a titre de medicaments et compositions pharmaceutiques les renfermant
RU2339624C2 (ru) 2002-12-12 2008-11-27 Авентис Фарма С.А. Производные аминоиндазолов и их применение в качестве ингибиторов киназ
US20050019366A1 (en) 2002-12-31 2005-01-27 Zeldis Jerome B. Drug-coated stents and methods of use therefor
WO2005000813A1 (en) 2003-05-30 2005-01-06 Imclone Systems Incorporated Heteroarylamino-phenylketone derivatives and their use as kinase inhibitors
US20050090529A1 (en) 2003-07-31 2005-04-28 Pfizer Inc 3,5 Disubstituted indazole compounds with nitrogen-bearing 5-membered heterocycles, pharmaceutical compositions, and methods for mediating or inhibiting cell proliferation
SG146624A1 (en) 2003-09-11 2008-10-30 Kemia Inc Cytokine inhibitors
TWI344961B (en) 2003-10-15 2011-07-11 Ube Industries Novel indazole derivative
EP1692128A1 (en) 2003-11-19 2006-08-23 Signal Pharmaceuticals LLC Indazole compounds and methods of use thereof as protein kinase inhibitors
US20050107386A1 (en) 2003-11-19 2005-05-19 Rama Krishna Narla Methods of treating diseases and disorders by targeting multiple kinases
TW200524601A (en) 2003-12-05 2005-08-01 Bristol Myers Squibb Co Heterocyclic anti-migraine agents
DE102004028862A1 (de) * 2004-06-15 2005-12-29 Merck Patent Gmbh 3-Aminoindazole
JP4931823B2 (ja) 2004-10-18 2012-05-16 アムジエン・インコーポレーテツド チアジアゾール化合物及び使用方法
AU2006231023A1 (en) * 2005-04-04 2006-10-12 Merck Patent Gmbh Indazole squaric acid derivatives as CHK1-, CHK2- and SGK- inhibitors
DE102007002717A1 (de) * 2007-01-18 2008-07-24 Merck Patent Gmbh Heterocyclische Indazolderivate

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