|
DE2740053A1
(de)
*
|
1977-09-06 |
1979-05-03 |
Klaus Prof Dr Med Gersonde |
Verwendung von allosterischen effektoren mit hilfe von lipidvesikeln ueber eine irreversible inkorporierung zwecks verbesserter o tief 2 -entladung des haemoglobins in erythrozyten
|
|
US4192869A
(en)
*
|
1977-09-06 |
1980-03-11 |
Studiengesellschaft Kohle Mbh. |
Controlled improvement of the O2 release by intact erythrocytes with lipid vesicles
|
|
JPS5828878B2
(ja)
*
|
1980-08-20 |
1983-06-18 |
三金工業株式会社 |
環状ピロ燐酸エステル誘導体
|
|
US4473496A
(en)
*
|
1981-09-14 |
1984-09-25 |
The United States Of America As Represented By The Secretary Of The Army |
Intramolecularly crosslinked hemoglobin
|
|
FR2529463B1
(fr)
*
|
1982-07-05 |
1986-01-10 |
Centre Nat Rech Scient |
Procede et dispositif pour l'encapsulation dans les erythrocytes d'au moins une substance a activite biologique, notamment des effecteurs allosteriques de l'hemoglobine et erythrocytes ainsi obtenus
|
|
US4478824A
(en)
*
|
1983-08-08 |
1984-10-23 |
Franco Robert S |
Method for altering red blood cell function and survival
|
|
GB8328917D0
(en)
*
|
1983-10-28 |
1983-11-30 |
Fisons Plc |
Blood substitute
|
|
SE465951B
(sv)
*
|
1984-10-23 |
1991-11-25 |
Perstorp Ab |
Isomer av inositoltrifosfat foeretraedesvis i saltform foer anvaendning som terapeutiskt eller profylaktiskt medel samt kompositioner daerav
|
|
US5330979A
(en)
*
|
1984-10-23 |
1994-07-19 |
Perstorp Ab |
Method of treating renal disorders with inositoltriphosphate
|
|
US5545632A
(en)
*
|
1984-10-23 |
1996-08-13 |
Perstorp Ab |
Method of treating retroviral disease
|
|
US5015634A
(en)
*
|
1986-04-16 |
1991-05-14 |
Perstorp Ab |
Method of treating tissue damage with inositol triphosphate
|
|
US5023248A
(en)
*
|
1984-10-23 |
1991-06-11 |
Perstorp Ab |
Method of treating diabetes with inositol triphosphate
|
|
US5407924A
(en)
*
|
1984-10-23 |
1995-04-18 |
Perstorp Ab |
Method of treating pain using inositol triphosphate
|
|
SE465305B
(sv)
*
|
1986-04-16 |
1991-08-26 |
Perstorp Ab |
Anvaendning av inositolfosfat foer framstaellning av ett laekemedel
|
|
US4887995A
(en)
*
|
1985-01-22 |
1989-12-19 |
University Of Pittsburgh |
Method of treating sickle cell anemia
|
|
WO1987005598A1
(fr)
*
|
1986-03-11 |
1987-09-24 |
Mitsui Toatsu Chemicals, Incorporated |
Derives de myoinositol et procede de preparation
|
|
US5292913A
(en)
*
|
1986-03-11 |
1994-03-08 |
Mitsui Toatsu Chemicals, Incorporated |
Myoinositol derivatives and preparation process thereof
|
|
US4751244A
(en)
*
|
1986-04-04 |
1988-06-14 |
Merck & Co., Inc. |
Compounds useful in treating sickle cell anemia
|
|
US4731473A
(en)
*
|
1986-04-04 |
1988-03-15 |
Merck & Co., Inc. |
Compounds useful in treating sickle cell anemia
|
|
US4731381A
(en)
*
|
1986-04-04 |
1988-03-15 |
Merck & Co., Inc. |
Method of treating a person for sickle cell anemia
|
|
US4699926A
(en)
*
|
1986-04-04 |
1987-10-13 |
Merck & Co., Inc. |
Compounds useful in treating sickle cell anemia
|
|
US5135923A
(en)
*
|
1986-04-16 |
1992-08-04 |
Perstorp Ab |
Method of treating cardiovascular diseases
|
|
US5057507A
(en)
*
|
1986-04-16 |
1991-10-15 |
Perstorp Ab |
Method of alleviating bone damage with inositoltriphosphate
|
|
US5274161A
(en)
*
|
1986-11-26 |
1993-12-28 |
Perstorp Ab |
Derivatives of cyclohexane
|
|
US4847082A
(en)
*
|
1987-01-21 |
1989-07-11 |
Robert Sabin |
Method of treatment of Alzheimer's disease using phytic acid
|
|
US4873355A
(en)
*
|
1987-05-29 |
1989-10-10 |
E. I. Du Pont De Nemours And Company |
Process for regioselectively preparing phosphorylated inositols and other cyclitols
|
|
US4924023A
(en)
*
|
1987-05-29 |
1990-05-08 |
E. I. Du Pont De Nemours And Company |
Phosphorylated inositols
|
|
US4931276A
(en)
*
|
1987-10-30 |
1990-06-05 |
Franco Robert S |
Method for introducing desired agents into red blood cells
|
|
US4826675A
(en)
*
|
1988-02-17 |
1989-05-02 |
Colgate-Palmolive Company |
Anticalculus oral composition
|
|
US5043261A
(en)
*
|
1989-04-10 |
1991-08-27 |
Cryopharm Corporation |
Lyophilized and reconstituted red blood cell and hemosome compositions
|
|
US5082833A
(en)
*
|
1988-06-30 |
1992-01-21 |
Shamsuddin Abulkalam M |
Reduction of cell proliferation and enhancement of nk-cell activity
|
|
US4874690A
(en)
*
|
1988-08-26 |
1989-10-17 |
Cryopharm Corporation |
Lyophilization of red blood cells
|
|
US5264605A
(en)
*
|
1989-06-28 |
1993-11-23 |
Mitsui Toatsu Chemicals, Incorporated |
Myoinsitol derivatives, process for preparing same, phosphorylating agent, and its utilization
|
|
US5151539A
(en)
*
|
1989-07-03 |
1992-09-29 |
Akzo America Inc. |
Formation of tetraarylpyrophosphate
|
|
WO1991004258A1
(fr)
*
|
1989-09-22 |
1991-04-04 |
Mitsui Toatsu Chemicals, Incorporated |
Derive d'ionisotol et production de ce derive
|
|
JPH03115290A
(ja)
*
|
1989-09-28 |
1991-05-16 |
Yokohama Rubber Co Ltd:The |
1d―ミオイノシトール―1―リン酸の合成法
|
|
US5173426A
(en)
*
|
1989-10-06 |
1992-12-22 |
Yale University |
DNAs encoding genetically engineered low oxygen affinity mutants of human hemoglobin
|
|
US5210263A
(en)
*
|
1990-05-15 |
1993-05-11 |
University Of Pittsburgh |
Inositol phosphate analogs and methods for their use
|
|
US5295944A
(en)
*
|
1991-05-14 |
1994-03-22 |
Dana-Farber Cancer Institute |
Method for treating a tumor with ionizing radiation
|
|
US5260472A
(en)
*
|
1992-01-29 |
1993-11-09 |
The Board Of Governors For Higher Education State Of Rhode Island And Providence Plantations |
Efficient chemoenzymatic synthesis of D-myo-inositol 1,4,5-triphosphate, D-myo-inositol 1,3,4-triphosphate, and D-myo-inositol 1,3,4,5-tetraphosphate
|
|
US5296466A
(en)
*
|
1992-02-19 |
1994-03-22 |
Board Of Regents, The University Of Texas System |
Inhibition of nitric oxide-mediated hypotension and septic shock with iron-containing hemoprotein
|
|
US5344393A
(en)
*
|
1992-02-28 |
1994-09-06 |
Alliance Pharmaceutical Corp. |
Use of synthetic oxygen carriers to facilitate oxygen delivery
|
|
US5260287A
(en)
*
|
1992-05-11 |
1993-11-09 |
Board Of Regents, The University Of Texas System |
Polyphosphorylated organic compounds: compositions useful in protecting biological tissues
|
|
EP0690671B1
(en)
*
|
1993-03-23 |
2004-08-04 |
Cbr Laboratories, Inc. |
Method and apparatus for encapsulation of biologically-active substances in cells
|
|
US5866548A
(en)
*
|
1993-04-09 |
1999-02-02 |
The Regents Of The University Of California |
Caged membrane-permeant inositol phosphates
|
|
US5827837A
(en)
*
|
1993-08-20 |
1998-10-27 |
The Regents Of The University Of California |
Polyanion anti-inflammatory agents
|
|
SE502989C2
(sv)
*
|
1993-11-22 |
1996-03-04 |
Perstorp Ab |
Användning av en inositoltrisfosfatester för beredning av läkemedel
|
|
SE503122C2
(sv)
*
|
1993-11-22 |
1996-03-25 |
Perstorp Ab |
Användning av en inositoltrisfosfatester för behandling av inflammatoriska tillstånd
|
|
US5720921A
(en)
*
|
1995-03-10 |
1998-02-24 |
Entremed, Inc. |
Flow electroporation chamber and method
|
|
US6074605A
(en)
*
|
1995-03-10 |
2000-06-13 |
Entremed, Inc. |
Flow electroporation chamber and method
|
|
US5626884A
(en)
*
|
1995-08-18 |
1997-05-06 |
Lockett; Curtis G. |
Treatment of sickle cell disease
|
|
US6949517B1
(en)
*
|
1996-06-24 |
2005-09-27 |
Matti Siren |
Method of treating inflammatory, tissue repair and infectious conditions
|
|
US5880099A
(en)
*
|
1996-09-20 |
1999-03-09 |
The Regents Of The University Of California |
Inositol polyphosphates and methods of using same
|
|
US5977078A
(en)
*
|
1996-09-20 |
1999-11-02 |
The Regents Of The Univesity Of California |
Inositol polyphosphate derivatives and methods of using same
|
|
DE19649350A1
(de)
*
|
1996-11-28 |
1998-06-04 |
Hoechst Ag |
Inositolglykane mit insulinartiger Wirkung
|
|
US6096916A
(en)
*
|
1997-05-23 |
2000-08-01 |
Nutrimed Biotech |
Synthesis of D-3 phosphorylated phosphoinositides and analogues
|
|
US6187335B1
(en)
*
|
1997-12-31 |
2001-02-13 |
Orasomal Technologies, Inc. |
Polymerizable fatty acids, phospholipids and polymerized liposomes therefrom
|
|
US7309687B1
(en)
*
|
1999-04-13 |
2007-12-18 |
The Kenneth S. Warren Institute, Inc. |
Methods for treatment and prevention of neuromuscular and muscular conditions by peripherally administered erythropoietin
|
|
EP1272201B1
(de)
*
|
2000-04-12 |
2004-11-24 |
Bitop Aktiengesellschaft Für Biotechnische Optimierung |
Verwendung von kompatiblen soluten als substanzen mit radikalfangenden eigenschaften
|
|
US7084126B1
(en)
*
|
2000-05-01 |
2006-08-01 |
Healthpartners Research Foundation |
Methods and compositions for enhancing cellular function through protection of tissue components
|
|
WO2002009723A2
(en)
*
|
2000-08-01 |
2002-02-07 |
Gmp Companies, Inc. |
Ammonium salts of hemoglobin allosteric effectors, and uses thereof
|
|
US6610702B2
(en)
*
|
2000-08-01 |
2003-08-26 |
Gmp Oxycell, Inc. |
Ammonium salts of inositol hexaphosphate, and uses thereof
|
|
AU2002217808A1
(en)
*
|
2000-11-21 |
2002-06-03 |
Inologic, Inc. |
Inositol derivatives for increasing chloride secretion and inhibiting inflammation
|
|
US7300916B2
(en)
*
|
2001-02-27 |
2007-11-27 |
Yoshiko Yasuda |
Preventives/remedies for thickened scar, keloid or chronic arthritic diseases
|
|
EP1379275A4
(en)
*
|
2001-03-14 |
2005-12-21 |
Centocor Inc |
IMMUNOGLOBULIN-ASSOCIATED PROTEINS ASSOCIATED WITH OBSTRUCTIVE CHRONIC BRONCHOPNEUMOPATHY, COMPOSITIONS, METHODS AND USES
|
|
AU2002327006A1
(en)
*
|
2001-09-20 |
2003-04-01 |
Inologic, Inc. |
Method of modulating sodium ion absorption in epithelial cells
|
|
AU2003231157C1
(en)
*
|
2002-04-29 |
2009-02-26 |
Normoxys, Inc. |
Inositol pyrophosphates, and methods of use thereof
|
|
WO2004002403A2
(en)
*
|
2002-06-14 |
2004-01-08 |
Gmp Oxycell, Inc. |
Sterols bearing pendant allosteric effectors of hemoglobin, and uses thereof
|
|
US20050176627A1
(en)
*
|
2002-09-09 |
2005-08-11 |
Anthony Cerami |
Long acting erythropoietins that maintain tissue protective activity of endogenous erythropoietin
|
|
CA2520291A1
(en)
*
|
2003-03-27 |
2004-10-14 |
Inologic, Inc. |
Camphanylidene and phenylalkyl inositol polyphosphate compounds, compositions, and methods of their use
|
|
ES2232302B1
(es)
*
|
2003-11-07 |
2006-08-01 |
Universitat De Les Illes Balears |
Myo-inositol hexafosfato para uso topico.
|
|
US20070135389A1
(en)
*
|
2004-07-06 |
2007-06-14 |
Claude Nicolau |
Tumor eradication by inositol-tripyrophosphate
|
|
US20060258626A1
(en)
*
|
2004-07-06 |
2006-11-16 |
Claude Nicolau |
Use of inositol-tripyrophosphate in treating tumors and diseases
|
|
US20060106000A1
(en)
*
|
2004-07-06 |
2006-05-18 |
Claude Nicolau |
Use of inositol-tripyrophosphate in treating tumors and diseases
|
|
PL1863495T3
(pl)
*
|
2005-03-18 |
2015-06-30 |
Normoxys Inc |
Sól wapniowa 1,6:2,3:4,5-tripirofosforanu mioinozytolu jako efektor allosteryczny hemoglobiny w leczeniu raka
|
|
CN101686986A
(zh)
*
|
2006-12-29 |
2010-03-31 |
诺尔姆奥克西斯公司 |
环多醇和其衍生物及其治疗应用
|