JP2010523660A5 - - Google Patents
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- Publication number
- JP2010523660A5 JP2010523660A5 JP2010503027A JP2010503027A JP2010523660A5 JP 2010523660 A5 JP2010523660 A5 JP 2010523660A5 JP 2010503027 A JP2010503027 A JP 2010503027A JP 2010503027 A JP2010503027 A JP 2010503027A JP 2010523660 A5 JP2010523660 A5 JP 2010523660A5
- Authority
- JP
- Japan
- Prior art keywords
- use according
- cell carcinoma
- renal cell
- papillary renal
- cci
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US92275907P | 2007-04-10 | 2007-04-10 | |
| US60/922,759 | 2007-04-10 | ||
| PCT/US2008/004501 WO2008124125A1 (en) | 2007-04-10 | 2008-04-08 | Anti-tumor activity of temsirolimus in papillary renal cell cancer |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014259703A Division JP2015083595A (ja) | 2007-04-10 | 2014-12-24 | 乳頭状腎細胞癌におけるテムシロリムス(Temsirolimus)の抗腫瘍活性 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010523660A JP2010523660A (ja) | 2010-07-15 |
| JP2010523660A5 true JP2010523660A5 (enExample) | 2011-05-19 |
| JP5908669B2 JP5908669B2 (ja) | 2016-04-26 |
Family
ID=39619123
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010503027A Active JP5908669B2 (ja) | 2007-04-10 | 2008-04-08 | 乳頭状腎細胞癌におけるテムシロリムス(Temsirolimus)の抗腫瘍活性 |
| JP2014259703A Withdrawn JP2015083595A (ja) | 2007-04-10 | 2014-12-24 | 乳頭状腎細胞癌におけるテムシロリムス(Temsirolimus)の抗腫瘍活性 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014259703A Withdrawn JP2015083595A (ja) | 2007-04-10 | 2014-12-24 | 乳頭状腎細胞癌におけるテムシロリムス(Temsirolimus)の抗腫瘍活性 |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US8791097B2 (enExample) |
| EP (5) | EP2462934B1 (enExample) |
| JP (2) | JP5908669B2 (enExample) |
| KR (2) | KR20150002887A (enExample) |
| CN (2) | CN105769861A (enExample) |
| AU (1) | AU2008236621B2 (enExample) |
| CA (1) | CA2681451C (enExample) |
| CL (1) | CL2008001009A1 (enExample) |
| CY (2) | CY1116492T1 (enExample) |
| DK (2) | DK2462934T3 (enExample) |
| ES (2) | ES2586739T3 (enExample) |
| HR (2) | HRP20150678T1 (enExample) |
| HU (2) | HUE029052T2 (enExample) |
| IL (1) | IL200835A (enExample) |
| MX (1) | MX2009010954A (enExample) |
| PA (1) | PA8776101A1 (enExample) |
| PL (2) | PL2144611T3 (enExample) |
| PT (2) | PT2462934T (enExample) |
| RU (1) | RU2501559C2 (enExample) |
| SI (2) | SI2144611T1 (enExample) |
| TW (1) | TW200901989A (enExample) |
| WO (1) | WO2008124125A1 (enExample) |
| ZA (1) | ZA200907063B (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW200901989A (en) * | 2007-04-10 | 2009-01-16 | Wyeth Corp | Anti-tumor activity of CCI-779 in papillary renal cell cancer |
| EP2550964A1 (en) * | 2011-07-26 | 2013-01-30 | Universitat Pompeu-Fabra | Temsirolimus for use in the prevention and/or treatment of a delta 9-tetrahydrocannabinol-induced anxiety disorder |
| US10765665B2 (en) | 2015-11-24 | 2020-09-08 | Melin Jeffrey | Composition comprising combination of rapamycin and an activator of AMP kinase and use thereof for treating diseases |
| CN108143732A (zh) * | 2017-12-19 | 2018-06-12 | 江南大学 | 雷帕霉素和ω-3脂肪酸在制备治疗肾癌的药物中的用途 |
Family Cites Families (54)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4316885A (en) | 1980-08-25 | 1982-02-23 | Ayerst, Mckenna And Harrison, Inc. | Acyl derivatives of rapamycin |
| US4650803A (en) | 1985-12-06 | 1987-03-17 | University Of Kansas | Prodrugs of rapamycin |
| US5023264A (en) | 1990-07-16 | 1991-06-11 | American Home Products Corporation | Rapamycin oximes |
| US5023263A (en) | 1990-08-09 | 1991-06-11 | American Home Products Corporation | 42-oxorapamycin |
| US5221670A (en) | 1990-09-19 | 1993-06-22 | American Home Products Corporation | Rapamycin esters |
| US5233036A (en) | 1990-10-16 | 1993-08-03 | American Home Products Corporation | Rapamycin alkoxyesters |
| US5120842A (en) | 1991-04-01 | 1992-06-09 | American Home Products Corporation | Silyl ethers of rapamycin |
| US5100883A (en) | 1991-04-08 | 1992-03-31 | American Home Products Corporation | Fluorinated esters of rapamycin |
| US5118678A (en) | 1991-04-17 | 1992-06-02 | American Home Products Corporation | Carbamates of rapamycin |
| US5118677A (en) | 1991-05-20 | 1992-06-02 | American Home Products Corporation | Amide esters of rapamycin |
| US5162333A (en) | 1991-09-11 | 1992-11-10 | American Home Products Corporation | Aminodiesters of rapamycin |
| US5177203A (en) | 1992-03-05 | 1993-01-05 | American Home Products Corporation | Rapamycin 42-sulfonates and 42-(N-carboalkoxy) sulfamates useful as immunosuppressive agents |
| US5256790A (en) | 1992-08-13 | 1993-10-26 | American Home Products Corporation | 27-hydroxyrapamycin and derivatives thereof |
| GB9221220D0 (en) * | 1992-10-09 | 1992-11-25 | Sandoz Ag | Organic componds |
| US5434260A (en) | 1992-10-13 | 1995-07-18 | American Home Products Corporation | Carbamates of rapamycin |
| US5302584A (en) | 1992-10-13 | 1994-04-12 | American Home Products Corporation | Carbamates of rapamycin |
| US5480989A (en) | 1992-10-13 | 1996-01-02 | American Home Products Corporation | Carbamates of rapamycin |
| US5489680A (en) | 1992-10-13 | 1996-02-06 | American Home Products Corporation | Carbamates of rapamycin |
| US5480988A (en) | 1992-10-13 | 1996-01-02 | American Home Products Corporation | Carbamates of rapamycin |
| US5411967A (en) | 1992-10-13 | 1995-05-02 | American Home Products Corporation | Carbamates of rapamycin |
| US5262423A (en) | 1992-10-29 | 1993-11-16 | American Home Products Corporation | Rapamycin arylcarbonyl and alkoxycarbonyl carbamates as immunosuppressive and antifungal agents |
| US5258389A (en) | 1992-11-09 | 1993-11-02 | Merck & Co., Inc. | O-aryl, O-alkyl, O-alkenyl and O-alkynylrapamycin derivatives |
| US5260300A (en) | 1992-11-19 | 1993-11-09 | American Home Products Corporation | Rapamycin carbonate esters as immuno-suppressant agents |
| US5504091A (en) | 1993-04-23 | 1996-04-02 | American Home Products Corporation | Biotin esters of rapamycin |
| US5373014A (en) | 1993-10-08 | 1994-12-13 | American Home Products Corporation | Rapamycin oximes |
| US5378836A (en) | 1993-10-08 | 1995-01-03 | American Home Products Corporation | Rapamycin oximes and hydrazones |
| US5391730A (en) | 1993-10-08 | 1995-02-21 | American Home Products Corporation | Phosphorylcarbamates of rapamycin and oxime derivatives thereof |
| US5385908A (en) | 1993-11-22 | 1995-01-31 | American Home Products Corporation | Hindered esters of rapamycin |
| US5385910A (en) | 1993-11-22 | 1995-01-31 | American Home Products Corporation | Gem-distributed esters of rapamycin |
| US5385909A (en) | 1993-11-22 | 1995-01-31 | American Home Products Corporation | Heterocyclic esters of rapamycin |
| US5389639A (en) | 1993-12-29 | 1995-02-14 | American Home Products Company | Amino alkanoic esters of rapamycin |
| US5362718A (en) * | 1994-04-18 | 1994-11-08 | American Home Products Corporation | Rapamycin hydroxyesters |
| US5463048A (en) | 1994-06-14 | 1995-10-31 | American Home Products Corporation | Rapamycin amidino carbamates |
| US5491231A (en) | 1994-11-28 | 1996-02-13 | American Home Products Corporation | Hindered N-oxide esters of rapamycin |
| US5563145A (en) | 1994-12-07 | 1996-10-08 | American Home Products Corporation | Rapamycin 42-oximes and hydroxylamines |
| US5780462A (en) | 1995-12-27 | 1998-07-14 | American Home Products Corporation | Water soluble rapamycin esters |
| WO1998002441A2 (en) | 1996-07-12 | 1998-01-22 | Ariad Pharmaceuticals, Inc. | Non immunosuppressive antifungal rapalogs |
| TW557297B (en) | 1997-09-26 | 2003-10-11 | Abbott Lab | Rapamycin analogs having immunomodulatory activity, and pharmaceutical compositions containing same |
| AR029160A1 (es) * | 1999-04-08 | 2003-06-18 | Schering Corp | El uso del interferon-alfa pegilado para la preparacion de un medicamento para el tratamiento del carcinoma de celula renal, un kit y el uso del mismo |
| IL147803A0 (en) | 1999-08-24 | 2002-08-14 | Ariad Gene Therapeutics Inc | 28-epirapalogs |
| US6277983B1 (en) * | 2000-09-27 | 2001-08-21 | American Home Products Corporation | Regioselective synthesis of rapamycin derivatives |
| TWI286074B (en) * | 2000-11-15 | 2007-09-01 | Wyeth Corp | Pharmaceutical composition containing CCI-779 as an antineoplastic agent |
| TWI296196B (en) * | 2001-04-06 | 2008-05-01 | Wyeth Corp | Antineoplastic combinations |
| TWI233359B (en) * | 2001-04-06 | 2005-06-01 | Wyeth Corp | Pharmaceutical composition for treating neoplasm |
| US20020198137A1 (en) * | 2001-06-01 | 2002-12-26 | Wyeth | Antineoplastic combinations |
| UA77200C2 (en) * | 2001-08-07 | 2006-11-15 | Wyeth Corp | Antineoplastic combination of cci-779 and bkb-569 |
| RU2344821C2 (ru) | 2002-07-30 | 2009-01-27 | Уайт | Парентеральные композиции, содержащие гидроксиэфиры рапамицина |
| UA81265C2 (en) | 2002-09-17 | 2007-12-25 | Wyeth Corp | Granulate formulation of the rapamycin ester cci-779 and process for the preparation thereof |
| UA83484C2 (uk) * | 2003-03-05 | 2008-07-25 | Уайт | Спосіб лікування раку грудей комбінацією похідного рапаміцину і інгібітора ароматази - летрозолу, фармацевтична композиція |
| KR20060006058A (ko) * | 2003-04-22 | 2006-01-18 | 와이어쓰 | 항신생물성 배합물 |
| AU2004235395A1 (en) * | 2003-04-29 | 2004-11-11 | Wyeth | Methods for prognosis and treatment of solid tumors |
| JP4227649B2 (ja) | 2003-08-07 | 2009-02-18 | ワイス | Cci−779の位置選択的合成 |
| AR047988A1 (es) * | 2004-03-11 | 2006-03-15 | Wyeth Corp | Combinaciones antineoplásicas de cci-779 y rituximab |
| TW200901989A (en) * | 2007-04-10 | 2009-01-16 | Wyeth Corp | Anti-tumor activity of CCI-779 in papillary renal cell cancer |
-
2008
- 2008-03-31 TW TW097111684A patent/TW200901989A/zh unknown
- 2008-04-08 ES ES12153823.5T patent/ES2586739T3/es active Active
- 2008-04-08 MX MX2009010954A patent/MX2009010954A/es active IP Right Grant
- 2008-04-08 PL PL08742616T patent/PL2144611T3/pl unknown
- 2008-04-08 CA CA2681451A patent/CA2681451C/en active Active
- 2008-04-08 CN CN201610140376.1A patent/CN105769861A/zh active Pending
- 2008-04-08 EP EP12153823.5A patent/EP2462934B1/en not_active Revoked
- 2008-04-08 SI SI200831450T patent/SI2144611T1/sl unknown
- 2008-04-08 ES ES08742616.9T patent/ES2543853T3/es active Active
- 2008-04-08 AU AU2008236621A patent/AU2008236621B2/en active Active
- 2008-04-08 HR HRP20150678TT patent/HRP20150678T1/hr unknown
- 2008-04-08 EP EP16172931.4A patent/EP3106164A1/en not_active Withdrawn
- 2008-04-08 EP EP17176598.5A patent/EP3248601A1/en not_active Withdrawn
- 2008-04-08 PT PT121538235T patent/PT2462934T/pt unknown
- 2008-04-08 CN CN200880011269A patent/CN101678008A/zh active Pending
- 2008-04-08 HU HUE12153823A patent/HUE029052T2/hu unknown
- 2008-04-08 SI SI200831635A patent/SI2462934T1/sl unknown
- 2008-04-08 KR KR1020147033451A patent/KR20150002887A/ko not_active Ceased
- 2008-04-08 EP EP08742616.9A patent/EP2144611B9/en active Active
- 2008-04-08 WO PCT/US2008/004501 patent/WO2008124125A1/en not_active Ceased
- 2008-04-08 PL PL12153823.5T patent/PL2462934T3/pl unknown
- 2008-04-08 KR KR1020097021193A patent/KR101544222B1/ko active Active
- 2008-04-08 PT PT87426169T patent/PT2144611E/pt unknown
- 2008-04-08 DK DK12153823.5T patent/DK2462934T3/en active
- 2008-04-08 US US12/099,394 patent/US8791097B2/en active Active
- 2008-04-08 JP JP2010503027A patent/JP5908669B2/ja active Active
- 2008-04-08 HU HUE08742616A patent/HUE026022T4/hu unknown
- 2008-04-08 RU RU2009134479/15A patent/RU2501559C2/ru active
- 2008-04-08 DK DK08742616.9T patent/DK2144611T3/en active
- 2008-04-08 EP EP18174039.0A patent/EP3398597A1/en not_active Withdrawn
- 2008-04-09 CL CL200801009A patent/CL2008001009A1/es unknown
- 2008-04-10 PA PA20088776101A patent/PA8776101A1/es unknown
-
2009
- 2009-09-09 IL IL200835A patent/IL200835A/en active IP Right Grant
- 2009-10-09 ZA ZA2009/07063A patent/ZA200907063B/en unknown
-
2014
- 2014-12-24 JP JP2014259703A patent/JP2015083595A/ja not_active Withdrawn
-
2015
- 2015-07-13 CY CY20151100608T patent/CY1116492T1/el unknown
-
2016
- 2016-06-17 HR HRP20160698TT patent/HRP20160698T1/hr unknown
- 2016-06-29 CY CY20161100596T patent/CY1117701T1/el unknown
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