JP2010523605A5 - - Google Patents

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Publication number
JP2010523605A5
JP2010523605A5 JP2010502442A JP2010502442A JP2010523605A5 JP 2010523605 A5 JP2010523605 A5 JP 2010523605A5 JP 2010502442 A JP2010502442 A JP 2010502442A JP 2010502442 A JP2010502442 A JP 2010502442A JP 2010523605 A5 JP2010523605 A5 JP 2010523605A5
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Japan
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JP2010502442A
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English (en)
Japanese (ja)
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JP5412422B2 (ja
JP2010523605A (ja
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Priority claimed from PCT/EP2008/002519 external-priority patent/WO2008125207A1/en
Publication of JP2010523605A publication Critical patent/JP2010523605A/ja
Publication of JP2010523605A5 publication Critical patent/JP2010523605A5/ja
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Publication of JP5412422B2 publication Critical patent/JP5412422B2/ja
Expired - Fee Related legal-status Critical Current
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JP2010502442A 2007-04-13 2008-03-29 N−アミノインドールの遷移金属触媒合成 Expired - Fee Related JP5412422B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP07007585 2007-04-13
EP07007585.8 2007-04-13
PCT/EP2008/002519 WO2008125207A1 (en) 2007-04-13 2008-03-29 A transition metal catalyzed synthesis of n-aminoindoles

Publications (3)

Publication Number Publication Date
JP2010523605A JP2010523605A (ja) 2010-07-15
JP2010523605A5 true JP2010523605A5 (enExample) 2011-05-06
JP5412422B2 JP5412422B2 (ja) 2014-02-12

Family

ID=38457866

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010502442A Expired - Fee Related JP5412422B2 (ja) 2007-04-13 2008-03-29 N−アミノインドールの遷移金属触媒合成

Country Status (12)

Country Link
US (1) US8026375B2 (enExample)
EP (1) EP2134682B1 (enExample)
JP (1) JP5412422B2 (enExample)
KR (1) KR20100015546A (enExample)
CN (1) CN101657422A (enExample)
AT (1) ATE537142T1 (enExample)
AU (1) AU2008238379A1 (enExample)
BR (1) BRPI0810199A2 (enExample)
CA (1) CA2683578A1 (enExample)
IL (1) IL201253A0 (enExample)
MX (1) MX2009010536A (enExample)
WO (1) WO2008125207A1 (enExample)

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EP1831225A2 (en) 2004-11-19 2007-09-12 The Regents of the University of California Anti-inflammatory pyrazolopyrimidines
EA200870409A1 (ru) 2006-04-04 2009-04-28 Дзе Риджентс Оф Дзе Юниверсити Оф Калифорния Антагонисты киназы pi3
GB2467670B (en) 2007-10-04 2012-08-01 Intellikine Inc Chemical entities and therapeutic uses thereof
US8193182B2 (en) 2008-01-04 2012-06-05 Intellikine, Inc. Substituted isoquinolin-1(2H)-ones, and methods of use thereof
CA2711558C (en) 2008-01-04 2016-12-13 Intellikine, Inc. Phosphatidyl inositol-3 kinase inhibiting compounds
JP5547099B2 (ja) 2008-03-14 2014-07-09 インテリカイン, エルエルシー キナーゼ阻害剤および使用方法
US8993580B2 (en) 2008-03-14 2015-03-31 Intellikine Llc Benzothiazole kinase inhibitors and methods of use
WO2010006072A2 (en) 2008-07-08 2010-01-14 The Regents Of The University Of California Mtor modulators and uses thereof
AU2009268611B2 (en) 2008-07-08 2015-04-09 Intellikine, Llc Kinase inhibitors and methods of use
JP5731978B2 (ja) 2008-09-26 2015-06-10 インテリカイン, エルエルシー 複素環キナーゼ阻害剤
CA2740885C (en) 2008-10-16 2018-04-03 The Regents Of The University Of California Fused ring heteroaryl kinase inhibitors
US8476282B2 (en) 2008-11-03 2013-07-02 Intellikine Llc Benzoxazole kinase inhibitors and methods of use
EP2427195B1 (en) 2009-05-07 2019-05-01 Intellikine, LLC Heterocyclic compounds and uses thereof
WO2011047384A2 (en) 2009-10-16 2011-04-21 The Regents Of The University Of California Methods of inhibiting ire1
AU2011255218B2 (en) 2010-05-21 2015-03-12 Infinity Pharmaceuticals, Inc. Chemical compounds, compositions and methods for kinase modulation
JP2013545749A (ja) 2010-11-10 2013-12-26 インフィニティー ファーマシューティカルズ, インコーポレイテッド 複素環化合物及びその使用
AU2012205669B2 (en) 2011-01-10 2015-08-20 Infinity Pharmaceuticals Inc. Processes for preparing isoquinolinones and solid forms of isoquinolinones
CN102093334B (zh) * 2011-02-22 2013-05-08 郑州大学 一组稠环噻吩类化合物的合成方法
JP6130305B2 (ja) 2011-02-23 2017-05-17 インテリカイン, エルエルシー キナーゼ阻害剤の組み合わせおよびそれらの使用
US9056877B2 (en) 2011-07-19 2015-06-16 Infinity Pharmaceuticals, Inc. Heterocyclic compounds and uses thereof
JP6027610B2 (ja) 2011-07-19 2016-11-16 インフィニティー ファーマシューティカルズ, インコーポレイテッド 複素環式化合物及びその使用
EP2751093A1 (en) 2011-08-29 2014-07-09 Infinity Pharmaceuticals, Inc. Heterocyclic compounds and uses thereof
MX370814B (es) 2011-09-02 2020-01-08 Univ California Pirazolo[3,4-d]pirimidinas sustituidas y usos de las mismas.
US8940742B2 (en) 2012-04-10 2015-01-27 Infinity Pharmaceuticals, Inc. Heterocyclic compounds and uses thereof
US8828998B2 (en) 2012-06-25 2014-09-09 Infinity Pharmaceuticals, Inc. Treatment of lupus, fibrotic conditions, and inflammatory myopathies and other disorders using PI3 kinase inhibitors
MX2015003874A (es) 2012-09-26 2015-12-16 Univ California Modulacion de ire1.
KR102229478B1 (ko) 2012-11-01 2021-03-18 인피니티 파마슈티칼스, 인코포레이티드 Pi3 키나아제 동형단백질 조절인자를 사용하는 암의 치료
US9481667B2 (en) 2013-03-15 2016-11-01 Infinity Pharmaceuticals, Inc. Salts and solid forms of isoquinolinones and composition comprising and methods of using the same
PE20160685A1 (es) 2013-10-04 2016-07-23 Infinity Pharmaceuticals Inc Compuestos heterociclicos y usos de los mismos
US9751888B2 (en) 2013-10-04 2017-09-05 Infinity Pharmaceuticals, Inc. Heterocyclic compounds and uses thereof
CN103755621B (zh) * 2014-01-23 2015-08-05 清华大学 由芳基肼和炔烃制备多取代吲哚的方法
SG10201808053XA (en) 2014-03-19 2018-10-30 Infinity Pharmaceuticals Inc Heterocyclic compounds for use in the treatment of pi3k-gamma mediated disorders
US20150320755A1 (en) 2014-04-16 2015-11-12 Infinity Pharmaceuticals, Inc. Combination therapies
US9708348B2 (en) 2014-10-03 2017-07-18 Infinity Pharmaceuticals, Inc. Trisubstituted bicyclic heterocyclic compounds with kinase activities and uses thereof
WO2016069796A1 (en) * 2014-10-28 2016-05-06 Spectrum Spine Ip Holdings, Llc Expandable, adjustable inter-body fusion devices and methods
US10160761B2 (en) 2015-09-14 2018-12-25 Infinity Pharmaceuticals, Inc. Solid forms of isoquinolinones, and process of making, composition comprising, and methods of using the same
WO2017161116A1 (en) 2016-03-17 2017-09-21 Infinity Pharmaceuticals, Inc. Isotopologues of isoquinolinone and quinazolinone compounds and uses thereof as pi3k kinase inhibitors
US10919914B2 (en) 2016-06-08 2021-02-16 Infinity Pharmaceuticals, Inc. Heterocyclic compounds and uses thereof
MX391135B (es) 2016-06-24 2025-03-21 Infinity Pharmaceuticals Inc Terapias de combinacion.
KR102038977B1 (ko) * 2016-12-30 2019-11-01 사빅 에스케이 넥슬렌 컴퍼니 피티이 엘티디 신규한 시클로펜타[b]티오펜일 전이금속 화합물, 이를 포함하는 전이금속 촉매 조성물, 및 이를 이용한 에틸렌 단독중합체 또는 에틸렌과 α-올레핀의 공중합체의 제조방법
ES2974634T3 (es) 2018-12-21 2024-06-28 Celgene Corp Inhibidores de tienopiridinas de RIPK2
EP3898725B1 (en) * 2018-12-21 2025-10-01 Dow Global Technologies LLC Heterocycle-heterocycle-based group iv transition metal catalysts for olefin polymerization
CN116813522A (zh) * 2023-05-04 2023-09-29 广州方中化工有限公司 一种含吲哚的苯磺酰脲类化合物的制备方法与应用
CN118638038B (zh) * 2024-06-05 2024-12-03 常州大学 一种n-n轴手性吲哚酰胺类化合物及其合成方法

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EP0287982B1 (en) * 1987-04-24 1994-12-07 Hoechst-Roussel Pharmaceuticals Incorporated N-(Pyridinyl)-1H-indol-1-amines, a process for their preparation and their use as medicaments
US4983608A (en) 1989-09-05 1991-01-08 Hoechst-Roussell Pharmaceuticals, Inc. N-substituted-4-pyrimidinamines and pyrimidinediamines
DE60016068T2 (de) 1999-03-10 2005-11-03 Tosoh Corp., Shinnanyo Verfahren zur Herstellung Stickstoffheterocyclischer Verbindungen
FR2842196B1 (fr) * 2002-07-15 2006-01-13 Rhodia Polyamide Intermediates Procede de fabrication de composes nitriles a partir de composes a insaturation ethylenique
ATE442865T1 (de) 2004-04-08 2009-10-15 Jado Technologies Gmbh Dreigeteilte konjugate mit einer struktur, die mit zellmembran-rafts interagieren und ihre verwendung

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