JP2010523487A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2010523487A5 JP2010523487A5 JP2010500390A JP2010500390A JP2010523487A5 JP 2010523487 A5 JP2010523487 A5 JP 2010523487A5 JP 2010500390 A JP2010500390 A JP 2010500390A JP 2010500390 A JP2010500390 A JP 2010500390A JP 2010523487 A5 JP2010523487 A5 JP 2010523487A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- regulatory rna
- drug
- resistance
- minicells
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US90907407P | 2007-03-30 | 2007-03-30 | |
| US60/909,074 | 2007-03-30 | ||
| PCT/IB2008/002984 WO2009027830A2 (en) | 2007-03-30 | 2008-03-26 | Bacterially-derived, intact minicells that encompass plasmid-free functional nucleic acid for in vivo delivery to mammalian cells |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010523487A JP2010523487A (ja) | 2010-07-15 |
| JP2010523487A5 true JP2010523487A5 (https=) | 2010-08-26 |
| JP5167338B2 JP5167338B2 (ja) | 2013-03-21 |
Family
ID=40386454
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010500390A Active JP5167338B2 (ja) | 2007-03-30 | 2008-03-26 | 哺乳動物細胞へのinvivo送達のための、プラスミド非含有機能性核酸を含有するインタクトな細菌由来ミニセル |
Country Status (17)
| Country | Link |
|---|---|
| EP (5) | EP2145002B1 (https=) |
| JP (1) | JP5167338B2 (https=) |
| CN (2) | CN105854029B (https=) |
| AU (1) | AU2008291833B2 (https=) |
| CA (3) | CA2933978C (https=) |
| CY (1) | CY1119031T1 (https=) |
| DK (2) | DK2145002T3 (https=) |
| ES (2) | ES2534435T3 (https=) |
| HR (2) | HRP20150328T1 (https=) |
| LT (1) | LT2865755T (https=) |
| MX (1) | MX2009010411A (https=) |
| NZ (1) | NZ580487A (https=) |
| PL (2) | PL2145002T3 (https=) |
| PT (2) | PT2145002E (https=) |
| SG (2) | SG10201804257RA (https=) |
| SI (2) | SI2865755T1 (https=) |
| WO (1) | WO2009027830A2 (https=) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUE024999T2 (en) | 2004-08-26 | 2016-02-29 | Engeneic Molecular Delivery Pty Ltd | Introducing functional nucleic acids into mammalian cells with bacterial intact minicells |
| HRP20150328T1 (hr) * | 2007-03-30 | 2015-05-22 | Engeneic Molecular Delivery Pty Ltd. | Bakterijski dobivene, intaktne mini-stanice koje obuhvaä†aju funkcionalnu nukleinsku kiselinu, bez plazmida, za in vivo dopremu do stanica sisavaca |
| DE102009017908A1 (de) * | 2009-04-17 | 2010-10-21 | Kist-Europe Forschungsgesellschaft Mbh | Vektor für den Transport von mikrobiologischen Organismen zu Krankheitsherden |
| WO2011034421A1 (en) * | 2009-09-16 | 2011-03-24 | Stichting Het Nederlands Kanker Instituut | Fra-1 target genes as drug targets for treating cancer |
| RU2664698C2 (ru) | 2011-12-13 | 2018-08-21 | Энджинеик Молекьюлар Деливери Пти Лтд | Полученные из бактерий интактные мини-клетки для доставки лекарственных средств к опухолям мозга |
| US9006200B2 (en) | 2013-03-13 | 2015-04-14 | Asbestos Diseases Research Foundation | MicroRNA-based approach to treating malignant pleural mesothelioma |
| AP2016009153A0 (en) | 2013-10-04 | 2016-04-30 | Engeneic Molecular Delivery Pty Ltd | Combination tumor treatment with drug-loaded, bispecific ligand-targeted minicells and interferon-gamma |
| AU2015326407C1 (en) * | 2014-10-03 | 2021-06-24 | Engeneic Molecular Delivery Pty Ltd | Enhanced loading of intact, bacterially derived vesicles with small molecule compounds |
| CA3039010A1 (en) | 2016-10-06 | 2018-04-12 | Engeneic Molecular Delivery Pty Ltd | Bacterial minicells for delivering nucleic acid adjuvants and methods of using the same |
| EP3615659A4 (en) | 2017-04-28 | 2021-01-06 | Agrospheres, Inc. | COMPOSITIONS AND METHODS OF ENCAPSULATION AND SCALABLE DELIVERY OF AGROCHEMICALS |
| WO2018201160A1 (en) | 2017-04-28 | 2018-11-01 | Agrospheres, Inc. | Compositions and methods for enzyme immobilization |
| CA3073449A1 (en) | 2017-09-25 | 2019-03-28 | Agrospheres, Inc. | Compositions and methods for scalable production and delivery of biologicals |
| EP3826654A4 (en) | 2018-07-23 | 2022-07-06 | EnGeneIC Molecular Delivery Pty Ltd | COMPOSITIONS COMPRISING MINICELLS OF BACTERIAL ORIGIN AND THEIR METHODS OF USE |
| AU2020205040A1 (en) | 2019-01-04 | 2021-08-12 | Engeneic Molecular Delivery Pty Ltd | Encapsulated glycolipid antigens for treatment of neoplastic diseases |
| US20230044257A1 (en) * | 2019-12-23 | 2023-02-09 | Agrospheres, Inc. | Compositions and methods for enhanced uptake of active ingredients for animal health and nutrition |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL154598B (nl) | 1970-11-10 | 1977-09-15 | Organon Nv | Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking. |
| US3817837A (en) | 1971-05-14 | 1974-06-18 | Syva Corp | Enzyme amplification assay |
| US3939350A (en) | 1974-04-29 | 1976-02-17 | Board Of Trustees Of The Leland Stanford Junior University | Fluorescent immunoassay employing total reflection for activation |
| US3996345A (en) | 1974-08-12 | 1976-12-07 | Syva Company | Fluorescence quenching with immunological pairs in immunoassays |
| US4275149A (en) | 1978-11-24 | 1981-06-23 | Syva Company | Macromolecular environment control in specific receptor assays |
| US4277437A (en) | 1978-04-05 | 1981-07-07 | Syva Company | Kit for carrying out chemically induced fluorescence immunoassay |
| WO1981001145A1 (en) | 1979-10-18 | 1981-04-30 | Univ Illinois | Hydrolytic enzyme-activatible pro-drugs |
| US4366241A (en) | 1980-08-07 | 1982-12-28 | Syva Company | Concentrating zone method in heterogeneous immunoassays |
| US4496778A (en) | 1983-10-03 | 1985-01-29 | Exxon Research & Engineering Co. | Process for the hydroxylation of olefins using molecular oxygen, an osmium containing catalyst, a copper Co-catalyst, and an aromatic amine based promoter |
| US5260203A (en) | 1986-09-02 | 1993-11-09 | Enzon, Inc. | Single polypeptide chain binding molecules |
| GB8705477D0 (en) | 1987-03-09 | 1987-04-15 | Carlton Med Prod | Drug delivery systems |
| US4975278A (en) | 1988-02-26 | 1990-12-04 | Bristol-Myers Company | Antibody-enzyme conjugates in combination with prodrugs for the delivery of cytotoxic agents to tumor cells |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| EP1400536A1 (en) | 1991-06-14 | 2004-03-24 | Genentech Inc. | Method for making humanized antibodies |
| WO2000067776A1 (en) | 1999-05-11 | 2000-11-16 | Ortho-Mcneil Pharmaceuticals, Inc. | Pharmacokinetic and pharmacodynamic modeling of erythropoietin administration |
| JP4458846B2 (ja) | 2001-10-15 | 2010-04-28 | エンジーンアイシー モレキュラー デリバリー ピーティーワイ リミテッド | invitroおよびinvivoにおけるDNA導入および遺伝子療法のためのベクターとしての完全なミニ細胞 |
| US20040053289A1 (en) * | 2002-09-09 | 2004-03-18 | The Regents Of The University Of California | Short interfering nucleic acid hybrids and methods thereof |
| US7611885B2 (en) | 2003-06-24 | 2009-11-03 | Engeneic Molecular Delivery Pty, Ltd. | Pharmaceutically compatible method for purifying intact bacterial minicells |
| DK1694361T3 (da) | 2003-12-09 | 2011-06-06 | Engeneic Molecular Delivery Pty Ltd | Målrettet levering til ikke-phagocytiske pattedyrceller via bakterielt afledte intakte miniceller |
| DK2992901T3 (da) | 2004-02-02 | 2020-01-27 | Engeneic Molecular Delivery Pty Ltd | Sammensætninger og fremgangsmåder til målrettet in vitro- og in vivo-medicinlevering til pattedyrceller via bakterielt afledte intakte miniceller |
| HUE024999T2 (en) * | 2004-08-26 | 2016-02-29 | Engeneic Molecular Delivery Pty Ltd | Introducing functional nucleic acids into mammalian cells with bacterial intact minicells |
| HRP20150328T1 (hr) * | 2007-03-30 | 2015-05-22 | Engeneic Molecular Delivery Pty Ltd. | Bakterijski dobivene, intaktne mini-stanice koje obuhvaä†aju funkcionalnu nukleinsku kiselinu, bez plazmida, za in vivo dopremu do stanica sisavaca |
-
2008
- 2008-03-26 HR HRP20150328TT patent/HRP20150328T1/hr unknown
- 2008-03-26 SI SI200831798A patent/SI2865755T1/sl unknown
- 2008-03-26 SG SG10201804257RA patent/SG10201804257RA/en unknown
- 2008-03-26 CA CA2933978A patent/CA2933978C/en active Active
- 2008-03-26 EP EP08828079.7A patent/EP2145002B1/en active Active
- 2008-03-26 SI SI200831411T patent/SI2145002T1/sl unknown
- 2008-03-26 CA CA2682704A patent/CA2682704C/en active Active
- 2008-03-26 EP EP19172998.7A patent/EP3564372A1/en active Pending
- 2008-03-26 DK DK08828079.7T patent/DK2145002T3/en active
- 2008-03-26 EP EP12178465.6A patent/EP2532746A3/en not_active Withdrawn
- 2008-03-26 JP JP2010500390A patent/JP5167338B2/ja active Active
- 2008-03-26 LT LTEP15150129.3T patent/LT2865755T/lt unknown
- 2008-03-26 PL PL08828079T patent/PL2145002T3/pl unknown
- 2008-03-26 CA CA2844647A patent/CA2844647C/en active Active
- 2008-03-26 CN CN201610277472.0A patent/CN105854029B/zh active Active
- 2008-03-26 EP EP17153863.0A patent/EP3205724B1/en active Active
- 2008-03-26 PL PL15150129T patent/PL2865755T3/pl unknown
- 2008-03-26 PT PT88280797T patent/PT2145002E/pt unknown
- 2008-03-26 MX MX2009010411A patent/MX2009010411A/es active IP Right Grant
- 2008-03-26 EP EP15150129.3A patent/EP2865755B1/en active Active
- 2008-03-26 CN CN200880018076.XA patent/CN101715489B/zh active Active
- 2008-03-26 WO PCT/IB2008/002984 patent/WO2009027830A2/en not_active Ceased
- 2008-03-26 DK DK15150129.3T patent/DK2865755T3/en active
- 2008-03-26 AU AU2008291833A patent/AU2008291833B2/en active Active
- 2008-03-26 SG SG10201507969PA patent/SG10201507969PA/en unknown
- 2008-03-26 NZ NZ580487A patent/NZ580487A/en unknown
- 2008-03-26 PT PT151501293T patent/PT2865755T/pt unknown
- 2008-03-26 ES ES08828079.7T patent/ES2534435T3/es active Active
- 2008-03-26 ES ES15150129.3T patent/ES2626179T3/es active Active
-
2017
- 2017-05-02 CY CY20171100476T patent/CY1119031T1/el unknown
- 2017-05-02 HR HRP20170662TT patent/HRP20170662T1/hr unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2010523487A5 (https=) | ||
| Tekirdag et al. | MIR181A regulates starvation-and rapamycin-induced autophagy through targeting of ATG5 | |
| Iriana et al. | Hedgehog signaling: implications in cancers and viral infections | |
| Zhou et al. | Exosomes released from tumor-associated macrophages transfer miRNAs that induce a Treg/Th17 cell imbalance in epithelial ovarian cancer | |
| CA2577938A1 (en) | Delivering functional nucleic acids to mammalian cells via bacterially derived, intact minicells | |
| Li et al. | MiR-34a inhibits proliferation and migration of breast cancer through down-regulation of Bcl-2 and SIRT1 | |
| Rivera et al. | CSPG4 as a target of antibody-based immunotherapy for malignant mesothelioma | |
| Verma et al. | Targeting of PYK2 synergizes with EGFR antagonists in basal-like TNBC and circumvents HER3-associated resistance via the NEDD4–NDRG1 axis | |
| Beeraka et al. | The role of exosomes in stemness and neurodegenerative diseases—chemoresistant-cancer therapeutics and phytochemicals | |
| Fu et al. | Combination foretinib and anti-PD-1 antibody immunotherapy for colorectal carcinoma | |
| Zhu et al. | Long non‐coding RNA SNHG16 promotes proliferation and inhibits apoptosis of diffuse large B‐cell lymphoma cells by targeting miR‐497‐5p/PIM1 axis | |
| Wuerkenbieke et al. | miRNA-150 downregulation promotes pertuzumab resistance in ovarian cancer cells via AKT activation | |
| JP2018525001A5 (https=) | ||
| Seidenberg et al. | The AP-1 transcription factor Fosl-2 regulates autophagy in cardiac fibroblasts during myocardial fibrogenesis | |
| JP2011116755A5 (https=) | ||
| Sahin et al. | Biomarker-guided sequential targeted therapies to overcome therapy resistance in rapidly evolving highly aggressive mammary tumors | |
| Tang et al. | MicroRNA-31 induced by Fusobacterium nucleatum infection promotes colorectal cancer tumorigenesis | |
| Carew et al. | Rational cotargeting of HDAC6 and BET proteins yields synergistic antimyeloma activity | |
| Li et al. | Drug resistance in cancers: a free pass for bullying | |
| Lv et al. | Porcine circovirus type 2 ORF5 protein induces autophagy to promote viral replication via the PERK-eIF2α-ATF4 and mTOR-ERK1/2-AMPK signaling pathways in PK-15 cells | |
| JP2021509395A (ja) | がんの治療に使用するためのミルシクリブの製剤及びその治療的組み合わせ | |
| CN116368384A (zh) | 用于巨噬细胞调节的化合物、靶标和途径 | |
| Soroczynska et al. | Immunosuppressive extracellular vesicles as a linking factor in the development of tumor and endometriotic lesions in the gynecologic tract | |
| Meric-Bernstam et al. | Antitumor activity and biomarker analysis for TROP2 antibody–drug conjugate datopotamab deruxtecan in patient-derived breast cancer xenograft models | |
| Ji-Fu et al. | Suppression of lung cancer metastasis-related protein 1 (LCMR1) inhibits the growth of colorectal cancer cells |