JP2010521441A5 - - Google Patents
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- Publication number
- JP2010521441A5 JP2010521441A5 JP2009553162A JP2009553162A JP2010521441A5 JP 2010521441 A5 JP2010521441 A5 JP 2010521441A5 JP 2009553162 A JP2009553162 A JP 2009553162A JP 2009553162 A JP2009553162 A JP 2009553162A JP 2010521441 A5 JP2010521441 A5 JP 2010521441A5
- Authority
- JP
- Japan
- Prior art keywords
- peptide
- derived molecule
- molecule according
- group
- seq
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 108090000765 processed proteins & peptides Proteins 0.000 claims 16
- 150000001413 amino acids Chemical class 0.000 claims 5
- 210000004027 cell Anatomy 0.000 claims 4
- 102100032187 Androgen receptor Human genes 0.000 claims 3
- 108010080146 androgen receptors Proteins 0.000 claims 3
- 229940079593 drug Drugs 0.000 claims 3
- 239000003814 drug Substances 0.000 claims 3
- 150000002632 lipids Chemical class 0.000 claims 3
- 206010028980 Neoplasm Diseases 0.000 claims 2
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 2
- 125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 claims 2
- 239000002246 antineoplastic agent Substances 0.000 claims 2
- 238000000338 in vitro Methods 0.000 claims 2
- 239000000203 mixture Substances 0.000 claims 2
- 150000007523 nucleic acids Chemical group 0.000 claims 2
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 1
- KXDHJXZQYSOELW-UHFFFAOYSA-N Carbamic acid Chemical group NC(O)=O KXDHJXZQYSOELW-UHFFFAOYSA-N 0.000 claims 1
- 108010085330 Estradiol Receptors Proteins 0.000 claims 1
- 102100038595 Estrogen receptor Human genes 0.000 claims 1
- 206010060862 Prostate cancer Diseases 0.000 claims 1
- 208000000236 Prostatic Neoplasms Diseases 0.000 claims 1
- 102000004022 Protein-Tyrosine Kinases Human genes 0.000 claims 1
- 108090000412 Protein-Tyrosine Kinases Proteins 0.000 claims 1
- 102000000395 SH3 domains Human genes 0.000 claims 1
- 108050008861 SH3 domains Proteins 0.000 claims 1
- 230000002280 anti-androgenic effect Effects 0.000 claims 1
- 229940124651 anti-breast cancer agent Drugs 0.000 claims 1
- 230000000259 anti-tumor effect Effects 0.000 claims 1
- 239000000051 antiandrogen Substances 0.000 claims 1
- 239000000427 antigen Substances 0.000 claims 1
- 102000036639 antigens Human genes 0.000 claims 1
- 108091007433 antigens Proteins 0.000 claims 1
- 230000001580 bacterial effect Effects 0.000 claims 1
- 210000000481 breast Anatomy 0.000 claims 1
- 210000004899 c-terminal region Anatomy 0.000 claims 1
- 201000011510 cancer Diseases 0.000 claims 1
- 239000003183 carcinogenic agent Substances 0.000 claims 1
- 239000003153 chemical reaction reagent Substances 0.000 claims 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 1
- 238000001727 in vivo Methods 0.000 claims 1
- 230000003993 interaction Effects 0.000 claims 1
- 239000002502 liposome Substances 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 239000002088 nanocapsule Substances 0.000 claims 1
- 239000002245 particle Substances 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 229940124531 pharmaceutical excipient Drugs 0.000 claims 1
- 229920001184 polypeptide Polymers 0.000 claims 1
- 102000004196 processed proteins & peptides Human genes 0.000 claims 1
- 210000005267 prostate cell Anatomy 0.000 claims 1
- 229960005486 vaccine Drugs 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US89542407P | 2007-03-16 | 2007-03-16 | |
| US60/895,424 | 2007-03-16 | ||
| PCT/EP2008/053127 WO2008113770A2 (en) | 2007-03-16 | 2008-03-14 | Anti-androgen peptides and uses thereof in cancer therapy |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014001333A Division JP5998161B2 (ja) | 2007-03-16 | 2014-01-08 | 抗アンドロゲンペプチドおよび癌治療におけるその使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010521441A JP2010521441A (ja) | 2010-06-24 |
| JP2010521441A5 true JP2010521441A5 (enExample) | 2011-05-06 |
| JP5464344B2 JP5464344B2 (ja) | 2014-04-09 |
Family
ID=39766539
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009553162A Expired - Fee Related JP5464344B2 (ja) | 2007-03-16 | 2008-03-14 | 抗アンドロゲンペプチドおよび癌治療におけるその使用 |
| JP2014001333A Active JP5998161B2 (ja) | 2007-03-16 | 2014-01-08 | 抗アンドロゲンペプチドおよび癌治療におけるその使用 |
| JP2016090783A Active JP6545122B2 (ja) | 2007-03-16 | 2016-04-28 | 抗アンドロゲンペプチドおよび癌治療におけるその使用 |
| JP2019070528A Active JP6689430B2 (ja) | 2007-03-16 | 2019-04-02 | 抗アンドロゲンペプチドおよび癌治療におけるその使用 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014001333A Active JP5998161B2 (ja) | 2007-03-16 | 2014-01-08 | 抗アンドロゲンペプチドおよび癌治療におけるその使用 |
| JP2016090783A Active JP6545122B2 (ja) | 2007-03-16 | 2016-04-28 | 抗アンドロゲンペプチドおよび癌治療におけるその使用 |
| JP2019070528A Active JP6689430B2 (ja) | 2007-03-16 | 2019-04-02 | 抗アンドロゲンペプチドおよび癌治療におけるその使用 |
Country Status (15)
| Country | Link |
|---|---|
| US (3) | US20100189776A1 (enExample) |
| EP (2) | EP3412685A1 (enExample) |
| JP (4) | JP5464344B2 (enExample) |
| AU (1) | AU2008228274B2 (enExample) |
| CY (1) | CY1120436T1 (enExample) |
| DK (1) | DK2139917T3 (enExample) |
| ES (1) | ES2677566T3 (enExample) |
| HR (1) | HRP20181178T1 (enExample) |
| HU (1) | HUE039249T2 (enExample) |
| LT (1) | LT2139917T (enExample) |
| PL (1) | PL2139917T3 (enExample) |
| PT (1) | PT2139917T (enExample) |
| SI (1) | SI2139917T1 (enExample) |
| TR (1) | TR201809422T4 (enExample) |
| WO (1) | WO2008113770A2 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100189776A1 (en) | 2007-03-16 | 2010-07-29 | Cancer Research Technology Ltd | Anti-androgen peptides and uses thereof in cancer therapy |
| GB2496135B (en) * | 2011-11-01 | 2015-03-18 | Valirx Plc | Inhibitors of the interaction between a Src family kinase and an androgen receptor or estradiol receptor for treatment of endometriosis |
| GB2513615A (en) * | 2013-05-01 | 2014-11-05 | Cancer Rec Tech Ltd | Medical use |
| WO2014188775A1 (ja) * | 2013-05-23 | 2014-11-27 | 国立大学法人東北大学 | アンドロゲンレセプター活性依存性乳癌細胞株の作製方法、当該細胞株を用いたスクリーニング方法、ならびに乳癌患者におけるアンドロゲンレセプター活性依存性獲得の判定方法、キット及びマーカー |
| KR102417496B1 (ko) * | 2019-11-29 | 2022-07-06 | (주)수파드엘릭사 | 안드로겐 수용체의 활성을 억제하는 폡타이드 및 이를 이용하는 화장료 조성물 |
| EP4157309A1 (en) | 2020-06-01 | 2023-04-05 | Black Cat Bio Limited | Compositions and methods for treating infections and netopathy |
| AU2023215340A1 (en) * | 2022-02-04 | 2024-09-19 | AecorBio Inc. | Medicinal uses of oligopeptides in combination with an antiandrogen |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1005357A1 (en) * | 1997-04-14 | 2000-06-07 | The Regents Of The University Of California | Peptide antiestrogen compositions and methods for treating breast cancer |
| WO2000001813A2 (en) | 1998-06-30 | 2000-01-13 | The University Of British Columbia | Peptide inhibitors of androgen-independent activation of androgen receptor |
| WO2002060935A2 (en) * | 2000-12-21 | 2002-08-08 | The Government Of The United States As Represented By The Secretary Of The Department Of Health And Human Services | A chimeric protein comprising non-toxic pseudomonas exotoxin a and type iv pilin sequences |
| CA2446819A1 (en) * | 2001-05-08 | 2002-11-14 | Merck & Co., Inc. | Dna molecules encoding macaca mulatta androgen receptor |
| US7160989B2 (en) * | 2003-05-30 | 2007-01-09 | New York University | Antibodies that recognize and bind phosphorylated human androgen receptor and methods of using same |
| WO2007041497A2 (en) * | 2005-09-30 | 2007-04-12 | Cleveland Biolabs, Inc. | Modulation of androgen receptor |
| US20100189776A1 (en) * | 2007-03-16 | 2010-07-29 | Cancer Research Technology Ltd | Anti-androgen peptides and uses thereof in cancer therapy |
-
2008
- 2008-03-11 US US12/531,415 patent/US20100189776A1/en not_active Abandoned
- 2008-03-14 JP JP2009553162A patent/JP5464344B2/ja not_active Expired - Fee Related
- 2008-03-14 PL PL08717866T patent/PL2139917T3/pl unknown
- 2008-03-14 SI SI200831967T patent/SI2139917T1/sl unknown
- 2008-03-14 TR TR2018/09422T patent/TR201809422T4/tr unknown
- 2008-03-14 LT LTEP08717866.1T patent/LT2139917T/lt unknown
- 2008-03-14 DK DK08717866.1T patent/DK2139917T3/en active
- 2008-03-14 HR HRP20181178TT patent/HRP20181178T1/hr unknown
- 2008-03-14 PT PT87178661T patent/PT2139917T/pt unknown
- 2008-03-14 WO PCT/EP2008/053127 patent/WO2008113770A2/en not_active Ceased
- 2008-03-14 EP EP18155817.2A patent/EP3412685A1/en not_active Withdrawn
- 2008-03-14 HU HUE08717866A patent/HUE039249T2/hu unknown
- 2008-03-14 AU AU2008228274A patent/AU2008228274B2/en active Active
- 2008-03-14 ES ES08717866.1T patent/ES2677566T3/es active Active
- 2008-03-14 EP EP08717866.1A patent/EP2139917B1/en active Active
-
2014
- 2014-01-08 JP JP2014001333A patent/JP5998161B2/ja active Active
- 2014-12-18 US US14/575,065 patent/US9919023B2/en active Active
-
2016
- 2016-04-28 JP JP2016090783A patent/JP6545122B2/ja active Active
-
2018
- 2018-03-12 US US15/918,268 patent/US11560406B2/en active Active
- 2018-07-17 CY CY20181100740T patent/CY1120436T1/el unknown
-
2019
- 2019-04-02 JP JP2019070528A patent/JP6689430B2/ja active Active
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