JP2010520280A5 - - Google Patents

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Publication number
JP2010520280A5
JP2010520280A5 JP2009552676A JP2009552676A JP2010520280A5 JP 2010520280 A5 JP2010520280 A5 JP 2010520280A5 JP 2009552676 A JP2009552676 A JP 2009552676A JP 2009552676 A JP2009552676 A JP 2009552676A JP 2010520280 A5 JP2010520280 A5 JP 2010520280A5
Authority
JP
Japan
Prior art keywords
seq
notch2
notch1
numb1
composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2009552676A
Other languages
English (en)
Japanese (ja)
Other versions
JP2010520280A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2008/001694 external-priority patent/WO2008108910A2/en
Publication of JP2010520280A publication Critical patent/JP2010520280A/ja
Publication of JP2010520280A5 publication Critical patent/JP2010520280A5/ja
Withdrawn legal-status Critical Current

Links

JP2009552676A 2007-03-05 2008-02-08 ＮｏｔｃｈまたはＮｕｍｂ特異的免疫療法との相乗効果を有する、癌細胞の再生のネガティブな遺伝的制御 Withdrawn JP2010520280A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US90499407P 2007-03-05 2007-03-05
US95994607P 2007-07-18 2007-07-18
US95997107P 2007-07-18 2007-07-18
US96104607P 2007-07-18 2007-07-18
PCT/US2008/001694 WO2008108910A2 (en) 2007-03-05 2008-02-08 Negative genetic regulation of cancer cell renewal in synergy with notch- or numb-specific immunotherapy

Publications (2)

Publication Number Publication Date
JP2010520280A JP2010520280A (ja) 2010-06-10
JP2010520280A5 true JP2010520280A5 (enExample) 2012-04-12

Family

ID=39539638

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009552676A Withdrawn JP2010520280A (ja) 2007-03-05 2008-02-08 ＮｏｔｃｈまたはＮｕｍｂ特異的免疫療法との相乗効果を有する、癌細胞の再生のネガティブな遺伝的制御

Country Status (4)

Country Link
US (1) US20100062012A1 (enExample)
EP (1) EP2134356A2 (enExample)
JP (1) JP2010520280A (enExample)
WO (1) WO2008108910A2 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6984522B2 (en) 2000-08-03 2006-01-10 Regents Of The University Of Michigan Isolation and use of solid tumor stem cells
WO2007145840A2 (en) 2006-06-13 2007-12-21 Oncomed Pharmaceuticals, Inc. Compositions and methods for diagnosing and treating cancer
AU2008209482B2 (en) 2007-01-24 2014-05-01 Oncomed Pharmaceuticals, Inc. Compositions and methods for diagnosing and treating cancer
US9132189B2 (en) 2008-07-08 2015-09-15 Oncomed Pharmaceuticals, Inc. Notch1 binding agents and methods of use thereof
CA2729602A1 (en) 2008-07-08 2010-01-14 Oncomed Pharmaceuticals, Inc. Notch1 receptor binding agents and methods of use thereof
US9090690B2 (en) 2009-06-18 2015-07-28 Pfizer Inc. Anti Notch-1 antibodies
PH12012500574A1 (en) * 2009-09-30 2012-10-22 Genentech Inc Notch1-antagonist-resistant cancer(s) using notch3 antagonists
WO2011088215A2 (en) 2010-01-13 2011-07-21 Oncomed Pharmaceuticals, Inc. Notch1 binding agents and methods of use thereof
RU2622083C2 (ru) 2010-12-15 2017-06-09 ВАЙЕТ ЭлЭлСи Антитела против notch1
KR101535219B1 (ko) * 2011-11-18 2015-07-09 한국생명공학연구원 Ｎｏｔｃｈ３에 대한 인간 단일클론항체
US9944700B2 (en) 2013-03-13 2018-04-17 Novartis Ag Notch2 binding molecules for treating respiratory diseases
CN109467598B (zh) * 2018-11-28 2021-11-09 生命谷（海南）生物科技股份有限公司 肿瘤相关基因notch1突变短肽及其应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998057621A1 (en) * 1997-06-18 1998-12-23 The Trustees Of Columbia University In The City Ofnew York Angiogenic modulation by notch signal transduction
GB9927328D0 (en) * 1999-11-18 2000-01-12 Lorantis Ltd Immunotherapy
US20040126762A1 (en) * 2002-12-17 2004-07-01 Morris David W. Novel compositions and methods in cancer
CA2546017A1 (en) * 2003-11-26 2005-06-16 Health Research, Inc. Use of notch pathway interfering agents for treatment of plasma cell disorders
GB0421838D0 (en) * 2004-09-30 2004-11-03 Congenia S R L Cancer markers

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