JP2010513526A - 甲状腺ホルモン類縁体、拮抗剤および製剤のためのナノ粒子及び重合体製剤ならびにその使用 - Google Patents

甲状腺ホルモン類縁体、拮抗剤および製剤のためのナノ粒子及び重合体製剤ならびにその使用 Download PDF

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JP2010513526A
JP2010513526A JP2009542935A JP2009542935A JP2010513526A JP 2010513526 A JP2010513526 A JP 2010513526A JP 2009542935 A JP2009542935 A JP 2009542935A JP 2009542935 A JP2009542935 A JP 2009542935A JP 2010513526 A JP2010513526 A JP 2010513526A
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tetrac
thyroid hormone
nanoparticles
cells
angiogenesis
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JP2010513526A5 (cg-RX-API-DMAC7.html
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ポール ジェイ. デイビス,
シェーカー エー. ムーサ,
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シーエルエフ メディカル テクノロジー アクセラレーション プログラム インコーポレイテッド
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    • AHUMAN NECESSITIES
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    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • A61K9/5107Excipients; Inactive ingredients
    • A61K9/513Organic macromolecular compounds; Dendrimers
    • A61K9/5146Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
    • A61K9/5153Polyesters, e.g. poly(lactide-co-glycolide)
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    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
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JP2009542935A 2006-12-22 2007-12-21 甲状腺ホルモン類縁体、拮抗剤および製剤のためのナノ粒子及び重合体製剤ならびにその使用 Withdrawn JP2010513526A (ja)

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Application Number Priority Date Filing Date Title
US87677006P 2006-12-22 2006-12-22
US92211307P 2007-04-05 2007-04-05
US93622307P 2007-06-18 2007-06-18
US95900607P 2007-07-09 2007-07-09
US96701607P 2007-08-30 2007-08-30
US99489507P 2007-09-21 2007-09-21
US26207P 2007-10-23 2007-10-23
US393507P 2007-11-20 2007-11-20
PCT/US2007/026167 WO2008140507A2 (en) 2006-12-22 2007-12-21 Nanoparticle and polymer formulations for thyroid hormone analogs, antagonists, and formulations and uses thereof

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JP2010513526A true JP2010513526A (ja) 2010-04-30
JP2010513526A5 JP2010513526A5 (cg-RX-API-DMAC7.html) 2012-02-09

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2019517591A (ja) * 2016-06-07 2019-06-24 ナノファーマシューティカルズ エルエルシー αvβ3インテグリン甲状腺アンタゴニストにコンジュゲートした非開裂性ポリマー
US11186551B2 (en) 2020-04-29 2021-11-30 Nanopharmaceuticals Llc Composition of scalable thyrointegrin antagonists with improved retention in tumors
US11351137B2 (en) 2018-04-11 2022-06-07 Nanopharmaceuticals Llc Composition and method for dual targeting in treatment of neuroendocrine tumors
US11723888B2 (en) 2021-12-09 2023-08-15 Nanopharmaceuticals Llc Polymer conjugated thyrointegrin antagonists

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8071134B2 (en) 2003-09-15 2011-12-06 Ordway Research Institute, Inc. Thyroid hormone analogs and methods of use
US7785632B2 (en) 2003-09-15 2010-08-31 Ordway Research Institute, Inc. Thyroid hormone analogs and methods of use
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