JP2010512974A5 - - Google Patents

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Publication number
JP2010512974A5
JP2010512974A5 JP2009543070A JP2009543070A JP2010512974A5 JP 2010512974 A5 JP2010512974 A5 JP 2010512974A5 JP 2009543070 A JP2009543070 A JP 2009543070A JP 2009543070 A JP2009543070 A JP 2009543070A JP 2010512974 A5 JP2010512974 A5 JP 2010512974A5
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JP
Japan
Prior art keywords
bmp
phosphate
acid
composition
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2009543070A
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English (en)
Japanese (ja)
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JP2010512974A (ja
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Priority claimed from US11/612,853 external-priority patent/US8048857B2/en
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Publication of JP2010512974A publication Critical patent/JP2010512974A/ja
Publication of JP2010512974A5 publication Critical patent/JP2010512974A5/ja
Withdrawn legal-status Critical Current

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JP2009543070A 2006-12-19 2007-12-12 流動性のキャリア組成物およびその使用方法 Withdrawn JP2010512974A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/612,853 US8048857B2 (en) 2006-12-19 2006-12-19 Flowable carrier compositions and methods of use
PCT/US2007/087117 WO2008079672A2 (en) 2006-12-19 2007-12-12 Flowable carrier compositions for orthopedic implants and methods of use

Publications (2)

Publication Number Publication Date
JP2010512974A JP2010512974A (ja) 2010-04-30
JP2010512974A5 true JP2010512974A5 (enExample) 2011-01-13

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ID=39528417

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009543070A Withdrawn JP2010512974A (ja) 2006-12-19 2007-12-12 流動性のキャリア組成物およびその使用方法

Country Status (4)

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US (1) US8048857B2 (enExample)
EP (1) EP2129318A2 (enExample)
JP (1) JP2010512974A (enExample)
WO (1) WO2008079672A2 (enExample)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040081704A1 (en) 1998-02-13 2004-04-29 Centerpulse Biologics Inc. Implantable putty material
US20020114795A1 (en) 2000-12-22 2002-08-22 Thorne Kevin J. Composition and process for bone growth and repair
US7955616B2 (en) * 2003-09-23 2011-06-07 Orthocon, Inc. Absorbable implants and methods for their use in hemostasis and in the treatment of osseous defects
AU2007234612B2 (en) 2006-12-14 2013-06-27 Johnson & Johnson Regenerative Therapeutics, Llc Protein stabilization formulations
US7718616B2 (en) 2006-12-21 2010-05-18 Zimmer Orthobiologics, Inc. Bone growth particles and osteoinductive composition thereof
US8383586B2 (en) * 2007-01-18 2013-02-26 Warsaw Orthopedic, Inc. Compositions and methods for soft tissue repair
US7678764B2 (en) 2007-06-29 2010-03-16 Johnson & Johnson Regenerative Therapeutics, Llc Protein formulations for use at elevated temperatures
WO2009020744A1 (en) 2007-08-07 2009-02-12 Johnson & Johnson Regenerative Therapeutics, Llc Protein formulations comprising gdf-5 in aqueous acidic solution
US20090110637A1 (en) * 2007-10-26 2009-04-30 Warsaw Orthopedic, Inc. LMP and Regulation of Tissue Growth
BRPI0911048A2 (pt) 2008-04-14 2015-12-29 Atrm Llc formulações líquidas tamponadas de gdf-5
US9616153B2 (en) 2008-04-17 2017-04-11 Warsaw Orthopedic, Inc. Rigid bone graft substitute
FR2932686B1 (fr) * 2008-06-23 2010-08-27 Centre Nat Rech Scient Combinaison de sang et de particules de ceramique de phosphates de calcium biphases.
FR2932687B1 (fr) * 2008-06-23 2010-09-17 Centre Nat Rech Scient Biomateriaux a base de phosphates de calcium.
CN101297980B (zh) * 2008-07-01 2011-11-23 北京奥精医药科技有限公司 含纳米羟基磷灰石/胶原微粒的骨修复材料及其制备方法
RU2421223C2 (ru) * 2008-12-15 2011-06-20 Государственное образовательное учреждение высшего профессионального образования "Дагестанская государственная медицинская академия федерального агентства по здравоохранению и социальному развитию" Способ лечения переломов длинных трубчатых костей при йододефицитных заболеваниях
RU2416411C2 (ru) * 2008-12-22 2011-04-20 Государственное образовательное учреждение высшего профессионального образования "Дагестанская государственная медицинская академия федерального агентства по здравоохранению и социальному развитию" Способ лечения переломов длинных трубчатых костей
AU2011329054B2 (en) 2010-11-15 2015-05-28 Zimmer Orthobiologics, Inc. Bone void fillers
US8524662B2 (en) 2010-12-28 2013-09-03 Depuy Mitek, Llc Compositions and methods for treating joints
US8455436B2 (en) 2010-12-28 2013-06-04 Depuy Mitek, Llc Compositions and methods for treating joints
US8398611B2 (en) 2010-12-28 2013-03-19 Depuy Mitek, Inc. Compositions and methods for treating joints
EP2688514A1 (en) 2011-03-21 2014-01-29 Endo Pharmaceuticals Inc. Urethral anastomosis device and method
CN102205149B (zh) * 2011-05-10 2013-10-02 中国科学院合肥物质科学研究院 羟基磷灰石/壳聚糖/聚乳酸复合骨修复材料及制备方法
US8623839B2 (en) 2011-06-30 2014-01-07 Depuy Mitek, Llc Compositions and methods for stabilized polysaccharide formulations
US11484578B2 (en) * 2012-02-01 2022-11-01 Children's Medical Center Corporation Biomaterial for articular cartilage maintenance and treatment of arthritis
AU2013318237A1 (en) 2012-09-18 2015-04-09 Goldberg, Roger P. Urethral anastomosis device
WO2014159186A1 (en) 2013-03-14 2014-10-02 Endo Pharmaceuticals Inc. Urethral anastomosis device
AU2015374114B2 (en) 2014-12-29 2018-07-26 Bioventus, Llc Systems and methods for improved delivery of osteoinductive molecules in bone repair
US9682099B2 (en) 2015-01-20 2017-06-20 DePuy Synthes Products, Inc. Compositions and methods for treating joints
WO2017011668A1 (en) * 2015-07-14 2017-01-19 Boston Scientific Scimed, Inc. Gel delivery catheters, systems, and methods
US10300172B2 (en) * 2015-10-30 2019-05-28 Bioventus, LLC. Matrix for enhanced delivery of osteoinductive molecules in bone repair
KR101780579B1 (ko) * 2016-01-20 2017-09-21 건양대학교산학협력단 주입형 인산칼슘-plga 복합 뼈수복재의 제조방법
US11020160B2 (en) * 2016-03-21 2021-06-01 Warsaw Orthopedic, Inc. Surgical injection system and method
EP3445411B1 (en) 2016-04-19 2025-02-19 Warsaw Orthopedic, Inc. An implantable composite containing carbonated hydroxyapatite
CA3026660A1 (en) 2016-06-10 2017-12-14 Bioventus, Llc Protein delivery with porous metallic structure
EP3938000A4 (en) * 2019-03-14 2022-11-16 BioMimetic Therapeutics, LLC PLATELET DERIVED GROWTH FACTOR FORMULATIONS TO IMPROVE BONE FUSION
US20200324025A1 (en) * 2019-04-10 2020-10-15 Globus Medical, Inc. Compositions containing bone morphogenic proteins and methods therof
US12599696B2 (en) 2019-07-26 2026-04-14 Warsaw Orthopedic, Inc. Hydratable and flowable implantable compositions and methods of making and using them
US11498880B2 (en) 2019-07-26 2022-11-15 Warsaw Orthopedic, Inc. Calcium phosphate granules and methods of making them
US11433159B2 (en) * 2019-07-26 2022-09-06 Warsaw Orthopedic, Inc. Hydratable and flowable implantable compositions and methods of making and using them

Family Cites Families (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3944655A (en) 1973-09-10 1976-03-16 Viobin Corporation Process of preparing food products from bones
US4394370A (en) 1981-09-21 1983-07-19 Jefferies Steven R Bone graft material for osseous defects and method of making same
US4472840A (en) 1981-09-21 1984-09-25 Jefferies Steven R Method of inducing osseous formation by implanting bone graft material
NL8402158A (nl) 1983-07-09 1985-02-01 Sumitomo Cement Co Poreus keramisch materiaal en werkwijze voor de bereiding daarvan.
US4563489A (en) 1984-02-10 1986-01-07 University Of California Biodegradable organic polymer delivery system for bone morphogenetic protein
DE3479402D1 (en) 1984-06-12 1989-09-21 Oscobal Ag Method of producing a bone replacement material
US5246457A (en) 1985-03-28 1993-09-21 Collagen Corporation Xenogeneic collagen/mineral preparations in bone repair
US4755593A (en) 1985-07-24 1988-07-05 Lauren Mark D Novel biomaterial of cross-linked peritoneal tissue
US4698326A (en) 1985-12-20 1987-10-06 Regents Of The University Of Minnesota Composition and method for osseous repair
US4780450A (en) 1985-12-20 1988-10-25 The University Of Maryland At Baltimore Physically stable composition and method of use thereof for osseous repair
US6311690B1 (en) 1986-03-27 2001-11-06 Gensci Orthobiologics, Inc. Bone repair material and delayed drug delivery system
US4865602A (en) 1986-11-06 1989-09-12 Collagen Corporation Gamma irradiation of collagen/mineral mixtures
FR2617488B1 (fr) 1987-07-01 1990-03-09 Tab Procede de fabrication de structures organisees de collagene, notamment d'origine humaine, et structures organisees de collagene correspondantes
JPH0773602B2 (ja) 1988-07-23 1995-08-09 新田ゼラチン株式会社 医科用および歯科用硬化性材料
US5231169A (en) 1990-10-17 1993-07-27 Norian Corporation Mineralized collagen
GB9122329D0 (en) 1991-10-22 1991-12-04 Isis Innovation Bioactive material
US5320844A (en) 1992-03-12 1994-06-14 Liu Sung Tsuen Composite materials for hard tissue replacement
US5532217A (en) 1992-04-24 1996-07-02 Silver; Frederick H. Process for the mineralization of collagen fibers, product produced thereby and use thereof to repair bone
US5531791A (en) 1993-07-23 1996-07-02 Bioscience Consultants Composition for repair of defects in osseous tissues, method of making, and prosthesis
US5707962A (en) 1994-09-28 1998-01-13 Gensci Regeneration Sciences Inc. Compositions with enhanced osteogenic potential, method for making the same and therapeutic uses thereof
US6180606B1 (en) 1994-09-28 2001-01-30 Gensci Orthobiologics, Inc. Compositions with enhanced osteogenic potential, methods for making the same and uses thereof
US5674292A (en) 1995-06-07 1997-10-07 Stryker Corporation Terminally sterilized osteogenic devices and preparation thereof
US6902584B2 (en) 1995-10-16 2005-06-07 Depuy Spine, Inc. Bone grafting matrix
US5776193A (en) 1995-10-16 1998-07-07 Orquest, Inc. Bone grafting matrix
US6048964A (en) 1995-12-12 2000-04-11 Stryker Corporation Compositions and therapeutic methods using morphogenic proteins and stimulatory factors
CA2221195A1 (en) 1997-11-14 1999-05-14 Chantal E. Holy Biodegradable polymer matrix
WO2000007639A1 (en) 1998-08-07 2000-02-17 Tissue Engineering, Inc. Bone precursor compositions
ES2187195T3 (es) 1998-09-11 2003-05-16 Gerhard Dr Schmidmaier Implantes biologicamente activos.
DE69918717T2 (de) * 1998-12-14 2005-07-21 Osteotech, Inc. Knochentransplantat aus knochenpartikel
ES2209820T3 (es) * 1999-02-04 2004-07-01 Sdgi Holdings, Inc. Composiciones esponjosas osteogenicas altamente mineralizadas, y usos de las mismas.
AU2984700A (en) 1999-02-12 2000-08-29 Collagenesis, Inc. Injectable collagen-based delivery system for bone morphogenic proteins
US6300315B1 (en) 1999-08-28 2001-10-09 Ceramedical, Inc. Mineralized collagen membrane and method of making same
ATE271886T1 (de) 1999-10-15 2004-08-15 Inst Genetics Llc Hyaluronsäure enthaltende zusammensetzungen zur abgabe osteogener proteine
EP1481695A1 (en) 1999-10-15 2004-12-01 Genetics Institute, LLC Formulations of hyaluronic acid for delivery of osteogenic proteins
CA2396016A1 (en) * 1999-12-29 2001-07-05 Andy Bernhardt System for reconstituting pastes and methods of using same
WO2001054746A2 (en) 2000-01-31 2001-08-02 Advanced Research And Technology Institute, Inc. Composite biomaterial including anisometric calcium phosphate reinforcement particles
AU2001244021A1 (en) * 2000-04-26 2001-11-07 Ecole Polytechnique Federale De Lausanne (Epfl) Calcium phosphate microgranules
US6485751B1 (en) 2000-05-30 2002-11-26 Industrial Technology Research Institute Resorbable calcium phosphate-based bio-compound particles and the manufacturing procedure thereof
DE10029520A1 (de) 2000-06-21 2002-01-17 Merck Patent Gmbh Beschichtung für metallische Implantatmaterialien
DE10037850A1 (de) 2000-08-01 2002-02-21 Herbert P Jennissen Verfahren zur Herstellung bioaktiver Implantatoberflächen
JP2002210002A (ja) 2001-01-18 2002-07-30 Foundation For Nara Institute Of Science & Technology 生体組織修復用組成物
JP2004533276A (ja) 2001-01-25 2004-11-04 リジェネレーション テクノロジーズ インク． 注射可能な多孔性骨グラフト材料
US6969523B1 (en) 2001-10-19 2005-11-29 Integra Lifesciences Corporation Collagen/glycosaminoglycan matrix stable to sterilizing by electron beam radiation
CH695985A5 (de) 2002-01-21 2006-11-15 Straumann Holding Ag Oberflächenmodifizierte Implantate.
US7166133B2 (en) * 2002-06-13 2007-01-23 Kensey Nash Corporation Devices and methods for treating defects in the tissue of a living being
CA2839032A1 (en) * 2003-05-19 2005-01-06 The Trustees Of Columbia University In The City Of New York Compositions and methods for treating and preventing heart tissue degeneration, and uses thereof
US20050020506A1 (en) 2003-07-25 2005-01-27 Drapeau Susan J. Crosslinked compositions comprising collagen and demineralized bone matrix, methods of making and methods of use
DE602004005477T2 (de) 2003-09-12 2007-12-13 Wyeth Injizierbare feste Calciumphosphat-Stäbe zur Abgabe von osteogenen Proteinen
WO2005070439A1 (en) * 2004-01-09 2005-08-04 Regeneration Technologies Inc. Implant comprising a human muscle tissue matrix
DE202004005420U1 (de) 2004-03-31 2005-08-18 Technische Universität Dresden Modifizierter Calciumphosphatzement
US20080031914A1 (en) 2006-08-02 2008-02-07 Drapeau Susan J Flowable biomaterial composition

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