JP2010508305A5 - - Google Patents
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- Publication number
- JP2010508305A5 JP2010508305A5 JP2009534941A JP2009534941A JP2010508305A5 JP 2010508305 A5 JP2010508305 A5 JP 2010508305A5 JP 2009534941 A JP2009534941 A JP 2009534941A JP 2009534941 A JP2009534941 A JP 2009534941A JP 2010508305 A5 JP2010508305 A5 JP 2010508305A5
- Authority
- JP
- Japan
- Prior art keywords
- peptidomimetic
- seq
- fatty acid
- polypeptide
- isolated
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US85542206P | 2006-10-31 | 2006-10-31 | |
| US60/855,422 | 2006-10-31 | ||
| PCT/US2007/083027 WO2008070357A2 (en) | 2006-10-31 | 2007-10-30 | Smoothened polypeptides and methods of use |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013150706A Division JP5739484B2 (ja) | 2006-10-31 | 2013-07-19 | スムースンドポリペプチドおよび使用方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010508305A JP2010508305A (ja) | 2010-03-18 |
| JP2010508305A5 true JP2010508305A5 (enExample) | 2010-12-16 |
| JP5399255B2 JP5399255B2 (ja) | 2014-01-29 |
Family
ID=39492945
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009534941A Expired - Fee Related JP5399255B2 (ja) | 2006-10-31 | 2007-10-30 | スムースンドポリペプチドおよび使用方法 |
| JP2013150706A Expired - Fee Related JP5739484B2 (ja) | 2006-10-31 | 2013-07-19 | スムースンドポリペプチドおよび使用方法 |
| JP2015088291A Pending JP2015180630A (ja) | 2006-10-31 | 2015-04-23 | スムースンドポリペプチドおよび使用方法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013150706A Expired - Fee Related JP5739484B2 (ja) | 2006-10-31 | 2013-07-19 | スムースンドポリペプチドおよび使用方法 |
| JP2015088291A Pending JP2015180630A (ja) | 2006-10-31 | 2015-04-23 | スムースンドポリペプチドおよび使用方法 |
Country Status (13)
| Country | Link |
|---|---|
| US (3) | US8198402B2 (enExample) |
| EP (2) | EP2078036A2 (enExample) |
| JP (3) | JP5399255B2 (enExample) |
| KR (1) | KR101563010B1 (enExample) |
| CN (2) | CN101616931B (enExample) |
| AU (1) | AU2007329678A1 (enExample) |
| CA (1) | CA2667821A1 (enExample) |
| MY (2) | MY181496A (enExample) |
| NZ (1) | NZ576467A (enExample) |
| PH (1) | PH12013502425A1 (enExample) |
| SG (2) | SG178743A1 (enExample) |
| WO (1) | WO2008070357A2 (enExample) |
| ZA (1) | ZA200902894B (enExample) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008070357A2 (en) * | 2006-10-31 | 2008-06-12 | Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services | Smoothened polypeptides and methods of use |
| TWI433674B (zh) | 2006-12-28 | 2014-04-11 | Infinity Discovery Inc | 環杷明（ｃｙｃｌｏｐａｍｉｎｅ）類似物類 |
| CN104059124A (zh) | 2007-12-27 | 2014-09-24 | 无限药品股份有限公司 | 立体选择性还原的方法 |
| US20100297118A1 (en) * | 2007-12-27 | 2010-11-25 | Macdougall John | Therapeutic Cancer Treatments |
| US20090181997A1 (en) * | 2007-12-27 | 2009-07-16 | Grayzel David | Therapeutic cancer treatments |
| US8193182B2 (en) | 2008-01-04 | 2012-06-05 | Intellikine, Inc. | Substituted isoquinolin-1(2H)-ones, and methods of use thereof |
| JP6141015B2 (ja) | 2009-08-05 | 2017-06-07 | インフィニティ ファーマスーティカルズ、インク． | シクロパミン類似体の酵素によるアミノ基転移 |
| US20110183948A1 (en) * | 2010-01-15 | 2011-07-28 | Infinity Pharmaceuticals, Inc. | Treatment of fibrotic conditions using hedgehog inhibitors |
| AU2011255218B2 (en) | 2010-05-21 | 2015-03-12 | Infinity Pharmaceuticals, Inc. | Chemical compounds, compositions and methods for kinase modulation |
| US9376447B2 (en) | 2010-09-14 | 2016-06-28 | Infinity Pharmaceuticals, Inc. | Transfer hydrogenation of cyclopamine analogs |
| JP2013545749A (ja) | 2010-11-10 | 2013-12-26 | インフィニティー ファーマシューティカルズ， インコーポレイテッド | 複素環化合物及びその使用 |
| AU2012205669B2 (en) | 2011-01-10 | 2015-08-20 | Infinity Pharmaceuticals Inc. | Processes for preparing isoquinolinones and solid forms of isoquinolinones |
| JP6027610B2 (ja) | 2011-07-19 | 2016-11-16 | インフィニティー ファーマシューティカルズ， インコーポレイテッド | 複素環式化合物及びその使用 |
| US9056877B2 (en) | 2011-07-19 | 2015-06-16 | Infinity Pharmaceuticals, Inc. | Heterocyclic compounds and uses thereof |
| EP2751093A1 (en) | 2011-08-29 | 2014-07-09 | Infinity Pharmaceuticals, Inc. | Heterocyclic compounds and uses thereof |
| WO2013049332A1 (en) | 2011-09-29 | 2013-04-04 | Infinity Pharmaceuticals, Inc. | Inhibitors of monoacylglycerol lipase and methods of their use |
| US8940742B2 (en) | 2012-04-10 | 2015-01-27 | Infinity Pharmaceuticals, Inc. | Heterocyclic compounds and uses thereof |
| KR102229478B1 (ko) | 2012-11-01 | 2021-03-18 | 인피니티 파마슈티칼스, 인코포레이티드 | Pi3 키나아제 동형단백질 조절인자를 사용하는 암의 치료 |
| EP2925363A4 (en) | 2012-11-29 | 2016-11-09 | Strasspharma Llc | METHOD FOR MODULATING FOLLICLE-STIMULATING HORMONACTIVITY |
| US20160024051A1 (en) | 2013-03-15 | 2016-01-28 | Infinity Pharmaceuticals, Inc. | Salts and solid forms of isoquinolinones and composition comprising and methods of using the same |
| US9192609B2 (en) | 2013-04-17 | 2015-11-24 | Hedgepath Pharmaceuticals, Inc. | Treatment and prognostic monitoring of proliferation disorders using hedgehog pathway inhibitors |
| ES2834638T3 (es) | 2013-05-30 | 2021-06-18 | Infinity Pharmaceuticals Inc | Tratamiento de cánceres usando moduladores de isoforma de PI3 cinasa |
| US9751888B2 (en) | 2013-10-04 | 2017-09-05 | Infinity Pharmaceuticals, Inc. | Heterocyclic compounds and uses thereof |
| PE20160685A1 (es) | 2013-10-04 | 2016-07-23 | Infinity Pharmaceuticals Inc | Compuestos heterociclicos y usos de los mismos |
| WO2015061204A1 (en) | 2013-10-21 | 2015-04-30 | Infinity Pharmaceuticals, Inc. | Heterocyclic compounds and uses thereof |
| SG10201808053XA (en) | 2014-03-19 | 2018-10-30 | Infinity Pharmaceuticals Inc | Heterocyclic compounds for use in the treatment of pi3k-gamma mediated disorders |
| US20150320754A1 (en) | 2014-04-16 | 2015-11-12 | Infinity Pharmaceuticals, Inc. | Combination therapies |
| WO2015168079A1 (en) | 2014-04-29 | 2015-11-05 | Infinity Pharmaceuticals, Inc. | Pyrimidine or pyridine derivatives useful as pi3k inhibitors |
| US9708348B2 (en) | 2014-10-03 | 2017-07-18 | Infinity Pharmaceuticals, Inc. | Trisubstituted bicyclic heterocyclic compounds with kinase activities and uses thereof |
| KR101723649B1 (ko) * | 2014-10-23 | 2017-04-06 | 서울대학교산학협력단 | 신규한 펩티드 화합물, 이의 생산 방법, 및 이의 용도 |
| HRP20251395T1 (hr) | 2015-06-04 | 2026-02-13 | Sol-Gel Technologies Ltd. | Topikalne formulacije za isporuku spojeva inhibitora hedgehog signalnog puta i njihova uporaba |
| US10160761B2 (en) | 2015-09-14 | 2018-12-25 | Infinity Pharmaceuticals, Inc. | Solid forms of isoquinolinones, and process of making, composition comprising, and methods of using the same |
| US20170231968A1 (en) | 2016-02-11 | 2017-08-17 | PellePharm, Inc. | Method for relief of and treatment of pruritus |
| JP6889432B2 (ja) * | 2016-04-28 | 2021-06-18 | 学校法人甲南学園 | 樹脂固定ペプチド |
| US10919914B2 (en) | 2016-06-08 | 2021-02-16 | Infinity Pharmaceuticals, Inc. | Heterocyclic compounds and uses thereof |
| MX391135B (es) | 2016-06-24 | 2025-03-21 | Infinity Pharmaceuticals Inc | Terapias de combinacion. |
| IL268771B2 (en) * | 2017-02-19 | 2024-06-01 | Nat Inst Biotechnology Negev Ltd | Peptide kinase inhibitors and methods of using them |
| CN108644311B (zh) * | 2018-05-22 | 2019-09-06 | 东北大学 | 一种基于硬化立方刚度吸振器实现方法及吸振器 |
| US12605387B2 (en) | 2020-07-24 | 2026-04-21 | Secura Bio, Inc. | Treatment of cancers using PI3 kinase isoform modulators |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4450150A (en) * | 1973-05-17 | 1984-05-22 | Arthur D. Little, Inc. | Biodegradable, implantable drug delivery depots, and method for preparing and using the same |
| IN165717B (enExample) | 1986-08-07 | 1989-12-23 | Battelle Memorial Institute | |
| JP3266311B2 (ja) | 1991-05-02 | 2002-03-18 | 生化学工業株式会社 | 新規ポリペプチドおよびこれを用いる抗ｈｉｖ剤 |
| AU8380898A (en) * | 1997-07-01 | 1999-01-25 | Ingham, Philip W | Vertebrate smoothened gene, gene products, and uses related thereto |
| IL125608A0 (en) * | 1998-07-30 | 1999-03-12 | Yeda Res & Dev | Tumor associated antigen peptides and use of same as anti-tumor vaccines |
| US6683192B2 (en) * | 2000-03-30 | 2004-01-27 | Curis, Inc. | Small organic molecule regulators of cell proliferation |
| EP2348047A1 (en) * | 2000-04-21 | 2011-07-27 | New England Medical Center | G protein coupled receptor (GPCR) agonists and antagonists and methods of activating and inhibiting GPCR using the same |
| EP2862570A1 (en) * | 2001-07-02 | 2015-04-22 | Sinan Tas | Use of cyclopamine in the treatment of basal cell carcinoma and other tumors |
| NZ530580A (en) * | 2001-07-27 | 2007-02-23 | Curis Inc | Mediators of hedgehog signaling pathways, compositions and uses related thereto |
| WO2004111636A2 (en) * | 2003-06-17 | 2004-12-23 | Vib Vzw | Peptide combos and their uses |
| AU2005304963C1 (en) * | 2004-11-04 | 2011-01-06 | Tufts Medical Center, Inc. | G protein coupled receptor agonists and antagonists and methods of use |
| US8088976B2 (en) * | 2005-02-24 | 2012-01-03 | Monsanto Technology Llc | Methods for genetic control of plant pest infestation and compositions thereof |
| WO2007134272A2 (en) * | 2006-05-12 | 2007-11-22 | Janssen Pharmaceutica N.V. | Humanized models via targeted mtagenesis with zinc finger nuclease |
| WO2008070357A2 (en) * | 2006-10-31 | 2008-06-12 | Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services | Smoothened polypeptides and methods of use |
-
2007
- 2007-10-30 WO PCT/US2007/083027 patent/WO2008070357A2/en not_active Ceased
- 2007-10-30 NZ NZ576467A patent/NZ576467A/xx not_active IP Right Cessation
- 2007-10-30 CN CN2007800460855A patent/CN101616931B/zh not_active Expired - Fee Related
- 2007-10-30 JP JP2009534941A patent/JP5399255B2/ja not_active Expired - Fee Related
- 2007-10-30 CN CN2013103343899A patent/CN103435694A/zh active Pending
- 2007-10-30 MY MYPI2013000956A patent/MY181496A/en unknown
- 2007-10-30 AU AU2007329678A patent/AU2007329678A1/en not_active Abandoned
- 2007-10-30 KR KR1020097008873A patent/KR101563010B1/ko not_active Expired - Fee Related
- 2007-10-30 SG SG2012007373A patent/SG178743A1/en unknown
- 2007-10-30 US US12/513,091 patent/US8198402B2/en not_active Expired - Fee Related
- 2007-10-30 EP EP07871292A patent/EP2078036A2/en not_active Withdrawn
- 2007-10-30 MY MYPI20091748A patent/MY149170A/en unknown
- 2007-10-30 EP EP11179413A patent/EP2431388A1/en not_active Withdrawn
- 2007-10-30 SG SG2011080447A patent/SG175691A1/en unknown
- 2007-10-30 CA CA002667821A patent/CA2667821A1/en not_active Abandoned
-
2009
- 2009-04-28 ZA ZA200902894A patent/ZA200902894B/xx unknown
-
2012
- 2012-05-14 US US13/470,965 patent/US8546524B2/en not_active Expired - Fee Related
-
2013
- 2013-07-19 JP JP2013150706A patent/JP5739484B2/ja not_active Expired - Fee Related
- 2013-08-01 US US13/956,628 patent/US20130316957A1/en not_active Abandoned
- 2013-11-22 PH PH12013502425A patent/PH12013502425A1/en unknown
-
2015
- 2015-04-23 JP JP2015088291A patent/JP2015180630A/ja active Pending
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