JP2010508305A5 - - Google Patents
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- Publication number
- JP2010508305A5 JP2010508305A5 JP2009534941A JP2009534941A JP2010508305A5 JP 2010508305 A5 JP2010508305 A5 JP 2010508305A5 JP 2009534941 A JP2009534941 A JP 2009534941A JP 2009534941 A JP2009534941 A JP 2009534941A JP 2010508305 A5 JP2010508305 A5 JP 2010508305A5
- Authority
- JP
- Japan
- Prior art keywords
- peptidomimetic
- seq
- fatty acid
- polypeptide
- isolated
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US85542206P | 2006-10-31 | 2006-10-31 | |
| US60/855,422 | 2006-10-31 | ||
| PCT/US2007/083027 WO2008070357A2 (en) | 2006-10-31 | 2007-10-30 | Smoothened polypeptides and methods of use |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013150706A Division JP5739484B2 (ja) | 2006-10-31 | 2013-07-19 | スムースンドポリペプチドおよび使用方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010508305A JP2010508305A (ja) | 2010-03-18 |
| JP2010508305A5 true JP2010508305A5 (enExample) | 2010-12-16 |
| JP5399255B2 JP5399255B2 (ja) | 2014-01-29 |
Family
ID=39492945
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009534941A Expired - Fee Related JP5399255B2 (ja) | 2006-10-31 | 2007-10-30 | スムースンドポリペプチドおよび使用方法 |
| JP2013150706A Expired - Fee Related JP5739484B2 (ja) | 2006-10-31 | 2013-07-19 | スムースンドポリペプチドおよび使用方法 |
| JP2015088291A Pending JP2015180630A (ja) | 2006-10-31 | 2015-04-23 | スムースンドポリペプチドおよび使用方法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013150706A Expired - Fee Related JP5739484B2 (ja) | 2006-10-31 | 2013-07-19 | スムースンドポリペプチドおよび使用方法 |
| JP2015088291A Pending JP2015180630A (ja) | 2006-10-31 | 2015-04-23 | スムースンドポリペプチドおよび使用方法 |
Country Status (13)
| Country | Link |
|---|---|
| US (3) | US8198402B2 (enExample) |
| EP (2) | EP2431388A1 (enExample) |
| JP (3) | JP5399255B2 (enExample) |
| KR (1) | KR101563010B1 (enExample) |
| CN (2) | CN103435694A (enExample) |
| AU (1) | AU2007329678A1 (enExample) |
| CA (1) | CA2667821A1 (enExample) |
| MY (2) | MY181496A (enExample) |
| NZ (1) | NZ576467A (enExample) |
| PH (1) | PH12013502425B1 (enExample) |
| SG (2) | SG178743A1 (enExample) |
| WO (1) | WO2008070357A2 (enExample) |
| ZA (1) | ZA200902894B (enExample) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MY181496A (en) * | 2006-10-31 | 2020-12-23 | Government Of The United States Of America Represented By The Sec Dep Of Health And Human Services | Smoothened polypeptides and methods of use |
| TWI433674B (zh) | 2006-12-28 | 2014-04-11 | Infinity Discovery Inc | 環杷明（ｃｙｃｌｏｐａｍｉｎｅ）類似物類 |
| US20100297118A1 (en) * | 2007-12-27 | 2010-11-25 | Macdougall John | Therapeutic Cancer Treatments |
| EP3190121B1 (en) | 2007-12-27 | 2019-02-20 | Infinity Pharmaceuticals, Inc. | Methods for stereoselective reduction of cyclopamine 4-en-3-one derivative |
| CA2710377A1 (en) * | 2007-12-27 | 2009-07-09 | Infinity Pharmaceuticals, Inc. | Therapeutic cancer treatments |
| US8193182B2 (en) | 2008-01-04 | 2012-06-05 | Intellikine, Inc. | Substituted isoquinolin-1(2H)-ones, and methods of use thereof |
| WO2011017551A1 (en) | 2009-08-05 | 2011-02-10 | Infinity Pharmaceuticals, Inc. | Enzymatic transamination of cyclopamine analogs |
| WO2011088404A1 (en) * | 2010-01-15 | 2011-07-21 | Infinity Pharmaceuticals , Inc | Treatment of fibrotic conditions using hedgehog inhibitors |
| EP2571357B1 (en) | 2010-05-21 | 2016-07-06 | Infinity Pharmaceuticals, Inc. | Chemical compounds, compositions and methods for kinase modulation |
| WO2012037217A1 (en) | 2010-09-14 | 2012-03-22 | Infinity Pharmaceuticals, Inc. | Transfer hydrogenation of cyclopamine analogs |
| CN103298474B (zh) | 2010-11-10 | 2016-06-29 | 无限药品股份有限公司 | 杂环化合物及其用途 |
| TWI546305B (zh) | 2011-01-10 | 2016-08-21 | 英菲尼提製藥股份有限公司 | 製備異喹啉酮之方法及異喹啉酮之固體形式 |
| WO2013012918A1 (en) | 2011-07-19 | 2013-01-24 | Infinity Pharmaceuticals Inc. | Heterocyclic compounds and uses thereof |
| AU2012284088B2 (en) | 2011-07-19 | 2015-10-08 | Infinity Pharmaceuticals Inc. | Heterocyclic compounds and uses thereof |
| CA2846431A1 (en) | 2011-08-29 | 2013-03-07 | Infinity Pharmaceuticals Inc. | Heterocyclic compounds and uses thereof |
| US9630979B2 (en) | 2011-09-29 | 2017-04-25 | Infinity Pharmaceuticals, Inc. | Inhibitors of monoacylglycerol lipase and methods of their use |
| US8940742B2 (en) | 2012-04-10 | 2015-01-27 | Infinity Pharmaceuticals, Inc. | Heterocyclic compounds and uses thereof |
| CN105102000B (zh) | 2012-11-01 | 2021-10-22 | 无限药品公司 | 使用pi3激酶亚型调节剂的癌症疗法 |
| AU2013352256A1 (en) | 2012-11-29 | 2015-06-18 | Strasspharma, Llc | Methods of modulating follicle stimulating hormone activity |
| EP2970194A1 (en) | 2013-03-15 | 2016-01-20 | Infinity Pharmaceuticals, Inc. | Salts and solid forms of isoquinolinones and composition comprising and methods of using the same |
| US9192609B2 (en) | 2013-04-17 | 2015-11-24 | Hedgepath Pharmaceuticals, Inc. | Treatment and prognostic monitoring of proliferation disorders using hedgehog pathway inhibitors |
| SG10201709926VA (en) | 2013-05-30 | 2017-12-28 | Infinity Pharmaceuticals Inc | Treatment of cancers using pi3 kinase isoform modulators |
| US9751888B2 (en) | 2013-10-04 | 2017-09-05 | Infinity Pharmaceuticals, Inc. | Heterocyclic compounds and uses thereof |
| MX389256B (es) | 2013-10-04 | 2025-03-20 | Infinity Pharmaceuticals Inc | Compuestos heterociclicos y usos de los mismos. |
| WO2015061204A1 (en) | 2013-10-21 | 2015-04-30 | Infinity Pharmaceuticals, Inc. | Heterocyclic compounds and uses thereof |
| EA201691872A1 (ru) | 2014-03-19 | 2017-04-28 | Инфинити Фармасьютикалз, Инк. | Гетероциклические соединения для применения в лечении pi3k-гамма-опосредованных расстройств |
| US20150320754A1 (en) | 2014-04-16 | 2015-11-12 | Infinity Pharmaceuticals, Inc. | Combination therapies |
| WO2015168079A1 (en) | 2014-04-29 | 2015-11-05 | Infinity Pharmaceuticals, Inc. | Pyrimidine or pyridine derivatives useful as pi3k inhibitors |
| WO2016054491A1 (en) | 2014-10-03 | 2016-04-07 | Infinity Pharmaceuticals, Inc. | Heterocyclic compounds and uses thereof |
| KR101723649B1 (ko) * | 2014-10-23 | 2017-04-06 | 서울대학교산학협력단 | 신규한 펩티드 화합물, 이의 생산 방법, 및 이의 용도 |
| BR112017026103B1 (pt) | 2015-06-04 | 2023-10-03 | Sol-Gel Technologies Ltd | Composições tópicas com composto inibidor de hedgehog, sistema de entrega tópica e seus usos |
| CN108349985A (zh) | 2015-09-14 | 2018-07-31 | 无限药品股份有限公司 | 异喹啉酮的固体形式、其制备方法、包含其的组合物及其使用方法 |
| WO2017139497A1 (en) | 2016-02-11 | 2017-08-17 | PellePharm, Inc. | Hedgehog inhibitor for use in relief of and treatment of pruritus or itching |
| JP6889432B2 (ja) * | 2016-04-28 | 2021-06-18 | 学校法人甲南学園 | 樹脂固定ペプチド |
| WO2017214269A1 (en) | 2016-06-08 | 2017-12-14 | Infinity Pharmaceuticals, Inc. | Heterocyclic compounds and uses thereof |
| EP3474856B1 (en) | 2016-06-24 | 2022-09-14 | Infinity Pharmaceuticals, Inc. | Combination therapies |
| CN110520144B (zh) * | 2017-02-19 | 2024-04-05 | 本-古里安大学B.G.内盖夫技术和应用公司 | 肽激酶抑制剂及其使用方法 |
| CN108644311B (zh) * | 2018-05-22 | 2019-09-06 | 东北大学 | 一种基于硬化立方刚度吸振器实现方法及吸振器 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4450150A (en) | 1973-05-17 | 1984-05-22 | Arthur D. Little, Inc. | Biodegradable, implantable drug delivery depots, and method for preparing and using the same |
| IN165717B (enExample) | 1986-08-07 | 1989-12-23 | Battelle Memorial Institute | |
| JP3266311B2 (ja) | 1991-05-02 | 2002-03-18 | 生化学工業株式会社 | 新規ポリペプチドおよびこれを用いる抗ｈｉｖ剤 |
| AU8380898A (en) * | 1997-07-01 | 1999-01-25 | Ingham, Philip W | Vertebrate smoothened gene, gene products, and uses related thereto |
| IL125608A0 (en) * | 1998-07-30 | 1999-03-12 | Yeda Res & Dev | Tumor associated antigen peptides and use of same as anti-tumor vaccines |
| US6683192B2 (en) * | 2000-03-30 | 2004-01-27 | Curis, Inc. | Small organic molecule regulators of cell proliferation |
| AU2001257169C1 (en) * | 2000-04-21 | 2011-06-16 | Tufts Medical Center, Inc. | G-protein coupled receptor (GPCR) agonists and antagonists and methods of activating and inhibiting GPCR using the same |
| ES2534400T3 (es) * | 2001-07-02 | 2015-04-22 | Sinan Tas | Uso de ciclopamina en el tratamiento de carcinoma de células basales y otros tumores |
| EA007339B1 (ru) * | 2001-07-27 | 2006-08-25 | Кьюэрис, Инк. | Медиаторы путей передачи сигналов генами hedgehog, содержащие их композиции и способы применения указанных веществ |
| JP2007527503A (ja) * | 2003-06-17 | 2007-09-27 | プロノタ・エヌブイ | ペプチドコンボ及びそれらの使用 |
| CA2586344C (en) | 2004-11-04 | 2013-05-28 | New England Medical Center Hospitals, Inc. | G protein coupled receptor agonists and antagonists and methods of use |
| US8088976B2 (en) * | 2005-02-24 | 2012-01-03 | Monsanto Technology Llc | Methods for genetic control of plant pest infestation and compositions thereof |
| WO2007134272A2 (en) * | 2006-05-12 | 2007-11-22 | Janssen Pharmaceutica N.V. | Humanized models via targeted mtagenesis with zinc finger nuclease |
| MY181496A (en) * | 2006-10-31 | 2020-12-23 | Government Of The United States Of America Represented By The Sec Dep Of Health And Human Services | Smoothened polypeptides and methods of use |
-
2007
- 2007-10-30 MY MYPI2013000956A patent/MY181496A/en unknown
- 2007-10-30 SG SG2012007373A patent/SG178743A1/en unknown
- 2007-10-30 EP EP11179413A patent/EP2431388A1/en not_active Withdrawn
- 2007-10-30 AU AU2007329678A patent/AU2007329678A1/en not_active Abandoned
- 2007-10-30 CN CN2013103343899A patent/CN103435694A/zh active Pending
- 2007-10-30 SG SG2011080447A patent/SG175691A1/en unknown
- 2007-10-30 WO PCT/US2007/083027 patent/WO2008070357A2/en not_active Ceased
- 2007-10-30 EP EP07871292A patent/EP2078036A2/en not_active Withdrawn
- 2007-10-30 NZ NZ576467A patent/NZ576467A/xx not_active IP Right Cessation
- 2007-10-30 MY MYPI20091748A patent/MY149170A/en unknown
- 2007-10-30 KR KR1020097008873A patent/KR101563010B1/ko not_active Expired - Fee Related
- 2007-10-30 US US12/513,091 patent/US8198402B2/en not_active Expired - Fee Related
- 2007-10-30 JP JP2009534941A patent/JP5399255B2/ja not_active Expired - Fee Related
- 2007-10-30 CN CN2007800460855A patent/CN101616931B/zh not_active Expired - Fee Related
- 2007-10-30 CA CA002667821A patent/CA2667821A1/en not_active Abandoned
-
2009
- 2009-04-28 ZA ZA200902894A patent/ZA200902894B/xx unknown
-
2012
- 2012-05-14 US US13/470,965 patent/US8546524B2/en not_active Expired - Fee Related
-
2013
- 2013-07-19 JP JP2013150706A patent/JP5739484B2/ja not_active Expired - Fee Related
- 2013-08-01 US US13/956,628 patent/US20130316957A1/en not_active Abandoned
- 2013-11-22 PH PH12013502425A patent/PH12013502425B1/en unknown
-
2015
- 2015-04-23 JP JP2015088291A patent/JP2015180630A/ja active Pending
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