JP2010508305A5 - - Google Patents
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- Publication number
- JP2010508305A5 JP2010508305A5 JP2009534941A JP2009534941A JP2010508305A5 JP 2010508305 A5 JP2010508305 A5 JP 2010508305A5 JP 2009534941 A JP2009534941 A JP 2009534941A JP 2009534941 A JP2009534941 A JP 2009534941A JP 2010508305 A5 JP2010508305 A5 JP 2010508305A5
- Authority
- JP
- Japan
- Prior art keywords
- peptidomimetic
- seq
- fatty acid
- polypeptide
- isolated
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US85542206P | 2006-10-31 | 2006-10-31 | |
| US60/855,422 | 2006-10-31 | ||
| PCT/US2007/083027 WO2008070357A2 (en) | 2006-10-31 | 2007-10-30 | Smoothened polypeptides and methods of use |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013150706A Division JP5739484B2 (ja) | 2006-10-31 | 2013-07-19 | スムースンドポリペプチドおよび使用方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010508305A JP2010508305A (ja) | 2010-03-18 |
| JP2010508305A5 true JP2010508305A5 (enExample) | 2010-12-16 |
| JP5399255B2 JP5399255B2 (ja) | 2014-01-29 |
Family
ID=39492945
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009534941A Expired - Fee Related JP5399255B2 (ja) | 2006-10-31 | 2007-10-30 | スムースンドポリペプチドおよび使用方法 |
| JP2013150706A Expired - Fee Related JP5739484B2 (ja) | 2006-10-31 | 2013-07-19 | スムースンドポリペプチドおよび使用方法 |
| JP2015088291A Pending JP2015180630A (ja) | 2006-10-31 | 2015-04-23 | スムースンドポリペプチドおよび使用方法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013150706A Expired - Fee Related JP5739484B2 (ja) | 2006-10-31 | 2013-07-19 | スムースンドポリペプチドおよび使用方法 |
| JP2015088291A Pending JP2015180630A (ja) | 2006-10-31 | 2015-04-23 | スムースンドポリペプチドおよび使用方法 |
Country Status (13)
| Country | Link |
|---|---|
| US (3) | US8198402B2 (enExample) |
| EP (2) | EP2078036A2 (enExample) |
| JP (3) | JP5399255B2 (enExample) |
| KR (1) | KR101563010B1 (enExample) |
| CN (2) | CN103435694A (enExample) |
| AU (1) | AU2007329678A1 (enExample) |
| CA (1) | CA2667821A1 (enExample) |
| MY (2) | MY149170A (enExample) |
| NZ (1) | NZ576467A (enExample) |
| PH (1) | PH12013502425A1 (enExample) |
| SG (2) | SG175691A1 (enExample) |
| WO (1) | WO2008070357A2 (enExample) |
| ZA (1) | ZA200902894B (enExample) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2007329678A1 (en) * | 2006-10-31 | 2008-06-12 | Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services | Smoothened polypeptides and methods of use |
| TWI433674B (zh) | 2006-12-28 | 2014-04-11 | Infinity Discovery Inc | 環杷明（ｃｙｃｌｏｐａｍｉｎｅ）類似物類 |
| PE20091180A1 (es) * | 2007-12-27 | 2009-08-26 | Infinity Pharmaceuticals Inc | Tratamientos terapeuticos contra el cancer |
| US20100297118A1 (en) * | 2007-12-27 | 2010-11-25 | Macdougall John | Therapeutic Cancer Treatments |
| CA2710858A1 (en) | 2007-12-27 | 2009-07-09 | Infinity Pharmaceuticals, Inc. | Methods for stereoselective reduction |
| US8193182B2 (en) | 2008-01-04 | 2012-06-05 | Intellikine, Inc. | Substituted isoquinolin-1(2H)-ones, and methods of use thereof |
| AU2010279325B2 (en) | 2009-08-05 | 2016-10-20 | Infinity Pharmaceuticals, Inc. | Enzymatic transamination of cyclopamine analogs |
| US20110183948A1 (en) * | 2010-01-15 | 2011-07-28 | Infinity Pharmaceuticals, Inc. | Treatment of fibrotic conditions using hedgehog inhibitors |
| CA2799579A1 (en) | 2010-05-21 | 2011-11-24 | Intellikine, Inc. | Chemical compounds, compositions and methods for kinase modulation |
| US9394313B2 (en) | 2010-09-14 | 2016-07-19 | Infinity Pharmaceuticals, Inc. | Transfer hydrogenation of cyclopamine analogs |
| JP2013545749A (ja) | 2010-11-10 | 2013-12-26 | インフィニティー ファーマシューティカルズ， インコーポレイテッド | 複素環化合物及びその使用 |
| ES2637113T3 (es) | 2011-01-10 | 2017-10-10 | Infinity Pharmaceuticals, Inc. | Procedimientos para preparar isoquinolinonas y formas sólidas de isoquinolinonas |
| AR088218A1 (es) | 2011-07-19 | 2014-05-21 | Infinity Pharmaceuticals Inc | Compuestos heterociclicos utiles como inhibidores de pi3k |
| HK1198443A1 (en) | 2011-07-19 | 2015-04-24 | 无限药品股份有限公司 | Heterocyclic compounds and uses thereof |
| MX2014002542A (es) | 2011-08-29 | 2014-07-09 | Infinity Pharmaceuticals Inc | Compuestos heterociclicos y usos de los mismos. |
| WO2013049332A1 (en) | 2011-09-29 | 2013-04-04 | Infinity Pharmaceuticals, Inc. | Inhibitors of monoacylglycerol lipase and methods of their use |
| US8940742B2 (en) | 2012-04-10 | 2015-01-27 | Infinity Pharmaceuticals, Inc. | Heterocyclic compounds and uses thereof |
| AU2013337717B2 (en) | 2012-11-01 | 2018-10-25 | Infinity Pharmaceuticals, Inc. | Treatment of cancers using PI3 kinase isoform modulators |
| EP2925363A4 (en) | 2012-11-29 | 2016-11-09 | Strasspharma Llc | METHOD FOR MODULATING FOLLICLE-STIMULATING HORMONACTIVITY |
| WO2014151386A1 (en) | 2013-03-15 | 2014-09-25 | Infinity Pharmaceuticals, Inc. | Salts and solid forms of isoquinolinones and composition comprising and methods of using the same |
| US9192609B2 (en) | 2013-04-17 | 2015-11-24 | Hedgepath Pharmaceuticals, Inc. | Treatment and prognostic monitoring of proliferation disorders using hedgehog pathway inhibitors |
| CA2914284A1 (en) | 2013-05-30 | 2014-12-04 | Infinity Pharmaceuticals, Inc. | Treatment of cancers using pi3 kinase isoform modulators |
| PT3052485T (pt) | 2013-10-04 | 2021-10-22 | Infinity Pharmaceuticals Inc | Compostos heterocíclicos e suas utilizações |
| US9751888B2 (en) | 2013-10-04 | 2017-09-05 | Infinity Pharmaceuticals, Inc. | Heterocyclic compounds and uses thereof |
| US20160244452A1 (en) | 2013-10-21 | 2016-08-25 | Infinity Pharmaceuticals, Inc. | Heterocyclic compounds and uses thereof |
| MX382033B (es) | 2014-03-19 | 2025-03-13 | Infinity Pharmaceuticals Inc | Compuestos heterocíclicos para utilizarlos en el tratamiento de trastornos mediados por pi3k-gamma. |
| US20150320754A1 (en) | 2014-04-16 | 2015-11-12 | Infinity Pharmaceuticals, Inc. | Combination therapies |
| WO2015168079A1 (en) | 2014-04-29 | 2015-11-05 | Infinity Pharmaceuticals, Inc. | Pyrimidine or pyridine derivatives useful as pi3k inhibitors |
| WO2016054491A1 (en) | 2014-10-03 | 2016-04-07 | Infinity Pharmaceuticals, Inc. | Heterocyclic compounds and uses thereof |
| KR101723649B1 (ko) | 2014-10-23 | 2017-04-06 | 서울대학교산학협력단 | 신규한 펩티드 화합물, 이의 생산 방법, 및 이의 용도 |
| PL3302428T3 (pl) | 2015-06-04 | 2026-04-13 | Sol-Gel Technologies Ltd. | Preparaty do zastosowania miejscowego do dostarczania związków inhibitora hedgehog i ich zastosowanie |
| WO2017048702A1 (en) | 2015-09-14 | 2017-03-23 | Infinity Pharmaceuticals, Inc. | Solid forms of isoquinolinone derivatives, process of making, compositions comprising, and methods of using the same |
| WO2017139497A1 (en) | 2016-02-11 | 2017-08-17 | PellePharm, Inc. | Hedgehog inhibitor for use in relief of and treatment of pruritus or itching |
| JP6889432B2 (ja) * | 2016-04-28 | 2021-06-18 | 学校法人甲南学園 | 樹脂固定ペプチド |
| WO2017214269A1 (en) | 2016-06-08 | 2017-12-14 | Infinity Pharmaceuticals, Inc. | Heterocyclic compounds and uses thereof |
| SG11201811237WA (en) | 2016-06-24 | 2019-01-30 | Infinity Pharmaceuticals Inc | Combination therapies |
| CN110520144B (zh) * | 2017-02-19 | 2024-04-05 | 本-古里安大学B.G.内盖夫技术和应用公司 | 肽激酶抑制剂及其使用方法 |
| CN108644311B (zh) * | 2018-05-22 | 2019-09-06 | 东北大学 | 一种基于硬化立方刚度吸振器实现方法及吸振器 |
| WO2022019920A1 (en) | 2020-07-24 | 2022-01-27 | Verastem, Inc. | Treatment of cancers using pi3 kinase isoform modulators |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4450150A (en) | 1973-05-17 | 1984-05-22 | Arthur D. Little, Inc. | Biodegradable, implantable drug delivery depots, and method for preparing and using the same |
| IN165717B (enExample) | 1986-08-07 | 1989-12-23 | Battelle Memorial Institute | |
| JP3266311B2 (ja) | 1991-05-02 | 2002-03-18 | 生化学工業株式会社 | 新規ポリペプチドおよびこれを用いる抗ｈｉｖ剤 |
| AU8380898A (en) * | 1997-07-01 | 1999-01-25 | Ingham, Philip W | Vertebrate smoothened gene, gene products, and uses related thereto |
| IL125608A0 (en) * | 1998-07-30 | 1999-03-12 | Yeda Res & Dev | Tumor associated antigen peptides and use of same as anti-tumor vaccines |
| US6683192B2 (en) * | 2000-03-30 | 2004-01-27 | Curis, Inc. | Small organic molecule regulators of cell proliferation |
| EP2348047A1 (en) * | 2000-04-21 | 2011-07-27 | New England Medical Center | G protein coupled receptor (GPCR) agonists and antagonists and methods of activating and inhibiting GPCR using the same |
| EP1561464A3 (en) * | 2001-07-02 | 2007-04-25 | Sinan Tas | Use of cyclopamine in the treatment of basal cell carcinoma and other tumors |
| BR0211513A (pt) * | 2001-07-27 | 2005-08-30 | Curis Inc | Mediadores de caminhos sinalizantes de hedgehog, composições e usos relacionados ao mesmo |
| EP1634083A2 (en) * | 2003-06-17 | 2006-03-15 | VIB vzw | Peptide combos and their uses |
| JP2008519039A (ja) * | 2004-11-04 | 2008-06-05 | ニュー イングランド メデカル センター ホスピタルズ インク | Ｇタンパク質共役型受容体アゴニストおよびアンタゴニストならびに使用方法 |
| US8088976B2 (en) * | 2005-02-24 | 2012-01-03 | Monsanto Technology Llc | Methods for genetic control of plant pest infestation and compositions thereof |
| WO2007134272A2 (en) * | 2006-05-12 | 2007-11-22 | Janssen Pharmaceutica N.V. | Humanized models via targeted mtagenesis with zinc finger nuclease |
| AU2007329678A1 (en) | 2006-10-31 | 2008-06-12 | Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services | Smoothened polypeptides and methods of use |
-
2007
- 2007-10-30 AU AU2007329678A patent/AU2007329678A1/en not_active Abandoned
- 2007-10-30 JP JP2009534941A patent/JP5399255B2/ja not_active Expired - Fee Related
- 2007-10-30 CN CN2013103343899A patent/CN103435694A/zh active Pending
- 2007-10-30 US US12/513,091 patent/US8198402B2/en not_active Expired - Fee Related
- 2007-10-30 MY MYPI20091748A patent/MY149170A/en unknown
- 2007-10-30 KR KR1020097008873A patent/KR101563010B1/ko not_active Expired - Fee Related
- 2007-10-30 SG SG2011080447A patent/SG175691A1/en unknown
- 2007-10-30 SG SG2012007373A patent/SG178743A1/en unknown
- 2007-10-30 CN CN2007800460855A patent/CN101616931B/zh not_active Expired - Fee Related
- 2007-10-30 CA CA002667821A patent/CA2667821A1/en not_active Abandoned
- 2007-10-30 WO PCT/US2007/083027 patent/WO2008070357A2/en not_active Ceased
- 2007-10-30 EP EP07871292A patent/EP2078036A2/en not_active Withdrawn
- 2007-10-30 NZ NZ576467A patent/NZ576467A/xx not_active IP Right Cessation
- 2007-10-30 EP EP11179413A patent/EP2431388A1/en not_active Withdrawn
- 2007-10-30 MY MYPI2013000956A patent/MY181496A/en unknown
-
2009
- 2009-04-28 ZA ZA200902894A patent/ZA200902894B/xx unknown
-
2012
- 2012-05-14 US US13/470,965 patent/US8546524B2/en not_active Expired - Fee Related
-
2013
- 2013-07-19 JP JP2013150706A patent/JP5739484B2/ja not_active Expired - Fee Related
- 2013-08-01 US US13/956,628 patent/US20130316957A1/en not_active Abandoned
- 2013-11-22 PH PH12013502425A patent/PH12013502425A1/en unknown
-
2015
- 2015-04-23 JP JP2015088291A patent/JP2015180630A/ja active Pending
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