JP2010505432A - Ｐｃｓｋ９を調節するためのｒｎａアンタゴニスト化合物 - Google Patents

Ｐｃｓｋ９を調節するためのｒｎａアンタゴニスト化合物 Download PDF

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JP2010505432A
JP2010505432A JP2009531824A JP2009531824A JP2010505432A JP 2010505432 A JP2010505432 A JP 2010505432A JP 2009531824 A JP2009531824 A JP 2009531824A JP 2009531824 A JP2009531824 A JP 2009531824A JP 2010505432 A JP2010505432 A JP 2010505432A
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seq
oligomer
pcsk9
sequence
lna
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JP2010505432A5 (enExample
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エレン・マリー・ストラールップ
ニルス・フィスケル・ニルセン
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Roche Innovation Center Copenhagen AS
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Santaris Pharma AS
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JP2009531824A 2006-10-09 2007-10-09 Ｐｃｓｋ９を調節するためのｒｎａアンタゴニスト化合物 Withdrawn JP2010505432A (ja)

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US82873506P 2006-10-09 2006-10-09
US97293207P 2007-09-17 2007-09-17
US97740907P 2007-10-04 2007-10-04
PCT/EP2007/060703 WO2008043753A2 (en) 2006-10-09 2007-10-09 Rna antagonist compounds for the modulation of pcsk9

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JP2010505432A true JP2010505432A (ja) 2010-02-25
JP2010505432A5 JP2010505432A5 (enExample) 2010-12-02

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US (1) US20100216864A1 (enExample)
EP (2) EP2076597A2 (enExample)
JP (1) JP2010505432A (enExample)
AU (1) AU2007306361A1 (enExample)
CA (1) CA2666191C (enExample)
ES (1) ES2603379T3 (enExample)
IL (1) IL197668A0 (enExample)
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WO (1) WO2008043753A2 (enExample)

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WO2018216785A1 (ja) * 2017-05-26 2018-11-29 国立研究開発法人国立循環器病研究センター Ｐｃｓｋ９を標的としたアンチセンス核酸
JP2021119148A (ja) * 2015-03-20 2021-08-12 オーフス ウニベルシテット リポタンパク質代謝障害の治療のためのｐｃｓｋ９阻害剤

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JP6974872B2 (ja) 2017-06-30 2021-12-01 国立大学法人 東京医科歯科大学 ヘテロ二本鎖型ａｎｔｉｍｉＲ
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