JP2010503625A5 - - Google Patents

Download PDF

Info

Publication number
JP2010503625A5
JP2010503625A5 JP2009527720A JP2009527720A JP2010503625A5 JP 2010503625 A5 JP2010503625 A5 JP 2010503625A5 JP 2009527720 A JP2009527720 A JP 2009527720A JP 2009527720 A JP2009527720 A JP 2009527720A JP 2010503625 A5 JP2010503625 A5 JP 2010503625A5
Authority
JP
Japan
Prior art keywords
ylcarbamoyl
hydroxy
amino
phenylethyl
benzimidazol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2009527720A
Other languages
English (en)
Japanese (ja)
Other versions
JP5249226B2 (ja
JP2010503625A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2007/007613 external-priority patent/WO2008031509A1/de
Publication of JP2010503625A publication Critical patent/JP2010503625A/ja
Publication of JP2010503625A5 publication Critical patent/JP2010503625A5/ja
Application granted granted Critical
Publication of JP5249226B2 publication Critical patent/JP5249226B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2009527720A 2006-09-13 2007-08-31 凝固第ＩＸａ因子インヒビターとしての使用のためのイソセリン誘導体 Expired - Fee Related JP5249226B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102006042926.5 2006-09-13
DE102006042926 2006-09-13
PCT/EP2007/007613 WO2008031509A1 (de) 2006-09-13 2007-08-31 Isoserinderivate als inhibitoren des koagulationsfaktors ixa

Publications (3)

Publication Number Publication Date
JP2010503625A JP2010503625A (ja) 2010-02-04
JP2010503625A5 true JP2010503625A5 (https=) 2010-09-30
JP5249226B2 JP5249226B2 (ja) 2013-07-31

Family

ID=38847022

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009527720A Expired - Fee Related JP5249226B2 (ja) 2006-09-13 2007-08-31 凝固第ＩＸａ因子インヒビターとしての使用のためのイソセリン誘導体

Country Status (22)

Country Link
US (1) US8097758B2 (https=)
EP (1) EP2069289B1 (https=)
JP (1) JP5249226B2 (https=)
KR (1) KR20090050081A (https=)
CN (1) CN101516834B (https=)
AR (1) AR063708A1 (https=)
AU (1) AU2007297013B2 (https=)
BR (1) BRPI0716991A2 (https=)
CA (1) CA2663544A1 (https=)
CL (1) CL2007002652A1 (https=)
IL (1) IL197504A (https=)
MA (1) MA30707B1 (https=)
MX (1) MX2009002047A (https=)
MY (1) MY150745A (https=)
NO (1) NO20091110L (https=)
NZ (1) NZ575603A (https=)
RU (1) RU2446157C2 (https=)
SG (1) SG174080A1 (https=)
TW (1) TWI394570B (https=)
UY (1) UY30585A1 (https=)
WO (1) WO2008031509A1 (https=)
ZA (1) ZA200900807B (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2477604A1 (en) 2002-03-13 2003-09-25 Signum Biosciences, Inc. Modulation of protein methylation and phosphoprotein phosphate
US7923041B2 (en) 2005-02-03 2011-04-12 Signum Biosciences, Inc. Compositions and methods for enhancing cognitive function
WO2006084033A1 (en) 2005-02-03 2006-08-10 Signum Biosciences, Inc. Compositions and methods for enhancing cognitive function
AU2007293773B2 (en) * 2006-09-07 2013-01-31 Albert Einstein College Of Medicine, Inc. Acyclic amine inhibitors of 5'-methylthioadenosine phosphorylase and nucleosidase
JP5607025B2 (ja) 2008-04-21 2014-10-15 シグナム バイオサイエンシーズ， インコーポレイテッド 化合物、組成物およびそれらを作製する方法
WO2010065717A1 (en) 2008-12-05 2010-06-10 Mochida Pharmaceutical Co., Ltd. Morpholinone compounds as factor ixa inhibitors
JP2013503163A (ja) * 2009-08-31 2013-01-31 持田製薬株式会社 第ＩＸａ因子阻害薬としてのモルホリノン化合物
WO2015160636A1 (en) 2014-04-16 2015-10-22 Merck Sharp & Dohme Corp. Factor ixa inhibitors
CN109627218B (zh) * 2018-11-27 2022-03-29 深圳市龙华区中心医院 一种抗凝小分子化合物及其应用和包含其的药物

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4238260A1 (de) 1992-11-12 1994-05-19 Basf Ag Substituierte ortho-Ethenylphenylessigsäurederivate
CA2159649A1 (en) 1993-03-29 1994-10-13 Queen's University At Kingston Anticoagulant compounds
TW394760B (en) * 1993-09-07 2000-06-21 Hoffmann La Roche Novel Carboxamides, process for their preparation and pharmaceutical composition containing the same
FI974437A7 (fi) * 1995-06-06 1997-12-05 Pfizer Substituoituja N-(indoli-2-karbonyyli)amideja ja johdannaisia glykogee nifosforylaasi-inhibiittoreina
CA2224062C (en) * 1995-06-06 2001-09-04 Pfizer Limited Substituted n-(indole-2-carbonyl)-glycinamides and derivatives as glycogen phosphorylase inhibitors
HU227568B1 (en) * 1997-12-24 2011-08-29 Sanofi Aventis Deutschland Indole derivatives, as inhibitors os factor xa
US6451832B2 (en) * 1999-12-23 2002-09-17 Boehringer Ingelheim Pharma Kg Benzimidazoles with antithrombotic activity
CO5271699A1 (es) * 2000-01-24 2003-04-30 Pfizer Prod Inc Procedimiento para el tratamiento de cardiomiopatia utilizando inhibidores de la glucogeno fosforilasa
JP4666440B2 (ja) * 2000-06-30 2011-04-06 生化学工業株式会社 アミノアルコール誘導体
US6642252B2 (en) 2000-11-07 2003-11-04 Bristol-Myers Squibb Company Acid derivatives useful as serine protease inhibitors
EP1594505A4 (en) 2003-02-11 2008-08-13 Bristol Myers Squibb Co PHENYLGLYCIN DERIVATIVES USEFUL AS SERINE PROTEASE INHIBITORS
US7056932B2 (en) * 2003-12-19 2006-06-06 Hoffman-La Roche Inc. Heterocyclyl substituted 1-alkoxy acetic acid amides
US8211919B2 (en) * 2005-09-02 2012-07-03 Astellas Pharma Inc. Amide derivatives as rock inhibitors
US7816387B2 (en) * 2005-09-05 2010-10-19 Dainippon Sumitomo Pharma Co., Ltd. β secretase inhibitor

Similar Documents

Publication Publication Date Title
JP2010503625A5 (https=)
RU2009113602A (ru) Изосериновые производные для применения в качестве ингибиторов фактора свертывания крови ixa
CA2552050C (en) Substituted heterocycles and the uses thereof
JP6401773B2 (ja) Ｂｅｔブロモドメイン阻害剤およびこれを用いる治療方法
RU2014131390A (ru) ПРОИЗВОДНЫЕ ТИЕНО[3,2-d]ПИРИМИДИНА, ОБЛАДАЮЩИЕ ИНГИБИРУЮЩЕЙ АКТИВНОСТЬЮ В ОТНОШЕНИИ ПРОТЕИНКИНАЗ
US20110229438A1 (en) Method of inhibiting hepatitus c virus by combination of a 5,6-dihydro-1h-pyridin-2-one and one or more additional antiviral compounds
BR112021008991A2 (pt) derivados de 2,3-di-hidro-1h-pirrolo [3,4c]piridin-1-ona como inibidores de hpk1 para o tratamento de câncer
JP2009509989A5 (https=)
AU2013216935B2 (en) Heteroaryl compounds and methods of use thereof
AU2006232620A1 (en) Substituted heterocycles and their use as CHK1, PDK1 and PAK inhibitors
RU2005122447A (ru) Энантиомеры производных тиофенгидроксамовой кислоты и их применение в качестве ингибиторов гдац
CA2360233A1 (en) Methods of treating c1s-mediated diseases and conditions, and compounds and compositions therefor
EP1877057A1 (en) Use of pyrazolyl-pyrimidine derivatives in the treatment of pain
KR20120123678A (ko) 플라비비리다에 바이러스의 억제제
JP2004536869A5 (https=)
US20080039377A1 (en) Composition Comprising a Jnk Inhibitor and Cyclosporin
JP2010503624A5 (https=)
EP3253749B1 (en) Compounds with anti-tumoral activity
JP2011521981A5 (https=)
JP2010120974A5 (https=)
AR070441A1 (es) Clorotiofeno - amidas como inhibidores de los factores de coagulacion xa y trombina
TW200404062A (en) Imidazolamino compounds
JP2010511641A5 (https=)
JP2009511516A5 (https=)
RU2009113616A (ru) Тартратные производные для применения в качестве ингибиторов фактора свертывания крови ixa