JP2010502210A5 - - Google Patents
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- Publication number
- JP2010502210A5 JP2010502210A5 JP2009527228A JP2009527228A JP2010502210A5 JP 2010502210 A5 JP2010502210 A5 JP 2010502210A5 JP 2009527228 A JP2009527228 A JP 2009527228A JP 2009527228 A JP2009527228 A JP 2009527228A JP 2010502210 A5 JP2010502210 A5 JP 2010502210A5
- Authority
- JP
- Japan
- Prior art keywords
- ovol1
- stem cells
- cancer stem
- expression
- nucleic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 206010028980 Neoplasm Diseases 0.000 claims 12
- 201000011510 cancer Diseases 0.000 claims 12
- 238000000034 method Methods 0.000 claims 12
- 210000000130 stem cell Anatomy 0.000 claims 12
- 101001121371 Homo sapiens Putative transcription factor Ovo-like 1 Proteins 0.000 claims 7
- 102100026326 Putative transcription factor Ovo-like 1 Human genes 0.000 claims 7
- 108020004707 nucleic acids Proteins 0.000 claims 7
- 102000039446 nucleic acids Human genes 0.000 claims 7
- 150000007523 nucleic acids Chemical class 0.000 claims 7
- 101150012407 OVOL1 gene Proteins 0.000 claims 6
- 239000003795 chemical substances by application Substances 0.000 claims 5
- 230000009261 transgenic effect Effects 0.000 claims 5
- 210000004027 cell Anatomy 0.000 claims 4
- 108090000623 proteins and genes Proteins 0.000 claims 4
- 108020004999 messenger RNA Proteins 0.000 claims 3
- 201000009030 Carcinoma Diseases 0.000 claims 2
- 108091026890 Coding region Proteins 0.000 claims 2
- 108700008625 Reporter Genes Proteins 0.000 claims 2
- 238000000338 in vitro Methods 0.000 claims 2
- 102000004169 proteins and genes Human genes 0.000 claims 2
- 206010025323 Lymphomas Diseases 0.000 claims 1
- 238000000636 Northern blotting Methods 0.000 claims 1
- 108020004711 Nucleic Acid Probes Proteins 0.000 claims 1
- 108700020796 Oncogene Proteins 0.000 claims 1
- 238000011529 RT qPCR Methods 0.000 claims 1
- 210000001185 bone marrow Anatomy 0.000 claims 1
- 210000004556 brain Anatomy 0.000 claims 1
- 210000000481 breast Anatomy 0.000 claims 1
- 210000001072 colon Anatomy 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 230000000694 effects Effects 0.000 claims 1
- 208000037828 epithelial carcinoma Diseases 0.000 claims 1
- 230000003394 haemopoietic effect Effects 0.000 claims 1
- 210000003494 hepatocyte Anatomy 0.000 claims 1
- 238000003384 imaging method Methods 0.000 claims 1
- 210000004072 lung Anatomy 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000002853 nucleic acid probe Substances 0.000 claims 1
- 230000002611 ovarian Effects 0.000 claims 1
- 210000000496 pancreas Anatomy 0.000 claims 1
- 108091033319 polynucleotide Proteins 0.000 claims 1
- 102000040430 polynucleotide Human genes 0.000 claims 1
- 239000002157 polynucleotide Substances 0.000 claims 1
- 229920001184 polypeptide Polymers 0.000 claims 1
- 108090000765 processed proteins & peptides Proteins 0.000 claims 1
- 102000004196 processed proteins & peptides Human genes 0.000 claims 1
- 230000035755 proliferation Effects 0.000 claims 1
- 210000002307 prostate Anatomy 0.000 claims 1
- 238000003757 reverse transcription PCR Methods 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP06018771 | 2006-09-07 | ||
| PCT/IB2007/003648 WO2008029290A2 (en) | 2006-09-07 | 2007-09-07 | Identification of cancer stem cells using genetic markers |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010502210A JP2010502210A (ja) | 2010-01-28 |
| JP2010502210A5 true JP2010502210A5 (OSRAM) | 2010-10-28 |
Family
ID=39157635
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009527228A Pending JP2010502210A (ja) | 2006-09-07 | 2007-09-07 | 遺伝子マーカーを使用する癌幹細胞の同定 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20100034736A1 (OSRAM) |
| EP (1) | EP2059613A2 (OSRAM) |
| JP (1) | JP2010502210A (OSRAM) |
| CA (1) | CA2662843A1 (OSRAM) |
| WO (1) | WO2008029290A2 (OSRAM) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2384369A4 (en) * | 2009-01-30 | 2012-06-27 | Kci Licensing Inc | BIOLOGICAL TESTS ON ADULT STEM CELLS |
| KR101231235B1 (ko) | 2010-04-21 | 2013-02-08 | 고려대학교 산학협력단 | 전립선암 줄기세포 선별용 단백질성 마커 |
| KR101240199B1 (ko) | 2010-04-26 | 2013-03-06 | 고려대학교 산학협력단 | 대장암 줄기세포 선별용 단백질성 마커 |
| DK2734307T3 (da) * | 2011-07-21 | 2020-06-02 | Menarini Silicon Biosystems Spa | Assay til at indsamle og detektere cirkulerende multiple myelomceller fra blod |
| CN103151461A (zh) | 2013-02-27 | 2013-06-12 | 京东方科技集团股份有限公司 | 一种有机薄膜晶体管及其制备方法和制备装置 |
| EP2883962B1 (en) * | 2013-12-16 | 2017-09-13 | Humanitas Mirasole S.p.A. | High levels of EMT-TFs for the diagnosis of cancer, in particular of colorectal (CRC) and pancreatic (PC) cancer |
| KR101805181B1 (ko) | 2016-09-02 | 2017-12-07 | 충북대학교 산학협력단 | 인산화된 slug 단백질의 유사분열 세포에 대한 신규한 바이오 마커로서의 용도 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050089518A1 (en) * | 2001-12-07 | 2005-04-28 | Clarke Michael F. | Prospective identification and characterization of breast cancer stem cells |
| ES2195751B1 (es) * | 2001-11-27 | 2005-04-01 | Universidad De Salamanca (Otri) | Mamiferos no humanos transgenicos como modelos para patologias humanas con origen en celulas stem. |
| US20040241653A1 (en) * | 2001-12-31 | 2004-12-02 | Elena Feinstein | Methods for identifying marker genes for cancer |
| EP1432724A4 (en) * | 2002-02-20 | 2006-02-01 | Sirna Therapeutics Inc | INTERFERENCE MEDIATION INHIBITION OF GENE RNA FROM MAP KINASE |
| JP2005528115A (ja) * | 2002-05-31 | 2005-09-22 | ザ ボード オブ トラスティーズ オブ ザ リーランド スタンフォード ジュニア ユニバーシティ | 幹細胞および癌幹細胞を同定および単離する方法 |
| US20040170605A1 (en) * | 2003-02-27 | 2004-09-02 | Garcia Isidro Sanchez | Use of the slug gene as a genetic marker in functions mediated by SCF (stem cell factor) and applications |
| AU2004256425A1 (en) * | 2003-06-09 | 2005-01-20 | The Regents Of The University Of Michigan | Compositions and methods for treating and diagnosing cancer |
| US7927795B2 (en) * | 2003-06-09 | 2011-04-19 | Board Of Trustees Of The University Of Arkansas | Gene expression profiling in primary ovarian serous papillary tumors and normal ovarian epithelium |
| JP2005000056A (ja) * | 2003-06-11 | 2005-01-06 | Sumitomo Pharmaceut Co Ltd | ホルモン依存性癌疾患マーカー及びその利用 |
| WO2006002378A2 (en) * | 2004-06-23 | 2006-01-05 | Avalon Pharmaceuticals | Determining cancer-linked genes and therapeutic targets using molecular cytogenetic methods |
| ES2301268B1 (es) * | 2004-10-25 | 2009-05-01 | Centro De Investigacion Biomolecular Aplicada Salamanca, S.L. | Empleo del gen slug, o de sus productos de replicacion, transcripcion o expresion, en la identificacion, diagnostico, prevencion o tratamiento de la diseminacion del cancer y/o desarrollo de metastasis. |
| US10538742B2 (en) * | 2004-11-12 | 2020-01-21 | Cambridge Enterprise Limited | Methods and means related to cancer stem cells |
| US20070099209A1 (en) * | 2005-06-13 | 2007-05-03 | The Regents Of The University Of Michigan | Compositions and methods for treating and diagnosing cancer |
-
2007
- 2007-09-07 CA CA002662843A patent/CA2662843A1/en not_active Abandoned
- 2007-09-07 WO PCT/IB2007/003648 patent/WO2008029290A2/en not_active Ceased
- 2007-09-07 JP JP2009527228A patent/JP2010502210A/ja active Pending
- 2007-09-07 EP EP07825743A patent/EP2059613A2/en not_active Withdrawn
- 2007-09-07 US US12/440,369 patent/US20100034736A1/en not_active Abandoned
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