JP2010501604A5 - - Google Patents
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- Publication number
- JP2010501604A5 JP2010501604A5 JP2009525948A JP2009525948A JP2010501604A5 JP 2010501604 A5 JP2010501604 A5 JP 2010501604A5 JP 2009525948 A JP2009525948 A JP 2009525948A JP 2009525948 A JP2009525948 A JP 2009525948A JP 2010501604 A5 JP2010501604 A5 JP 2010501604A5
- Authority
- JP
- Japan
- Prior art keywords
- medicament according
- glucose level
- glucose
- ramipril
- patient
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000003814 drug Substances 0.000 claims 17
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims 12
- 239000008103 glucose Substances 0.000 claims 12
- HDACQVRGBOVJII-JBDAPHQKSA-N ramipril Chemical compound C([C@@H](C(=O)OCC)N[C@@H](C)C(=O)N1[C@@H](C[C@@H]2CCC[C@@H]21)C(O)=O)CC1=CC=CC=C1 HDACQVRGBOVJII-JBDAPHQKSA-N 0.000 claims 6
- 229960003401 ramipril Drugs 0.000 claims 6
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 5
- 208000035475 disorder Diseases 0.000 claims 5
- 208000002705 Glucose Intolerance Diseases 0.000 claims 4
- 201000001421 hyperglycemia Diseases 0.000 claims 4
- 201000009104 prediabetes syndrome Diseases 0.000 claims 4
- 206010012601 diabetes mellitus Diseases 0.000 claims 3
- 208000024172 Cardiovascular disease Diseases 0.000 claims 2
- 230000007211 cardiovascular event Effects 0.000 claims 2
- 230000004153 glucose metabolism Effects 0.000 claims 2
- 208000006454 hepatitis Diseases 0.000 claims 2
- 231100000283 hepatitis Toxicity 0.000 claims 2
- 150000003839 salts Chemical class 0.000 claims 2
- 206010002383 Angina Pectoris Diseases 0.000 claims 1
- 208000002330 Congenital Heart Defects Diseases 0.000 claims 1
- 206010019280 Heart failures Diseases 0.000 claims 1
- 208000001647 Renal Insufficiency Diseases 0.000 claims 1
- 206010049447 Tachyarrhythmia Diseases 0.000 claims 1
- 208000001871 Tachycardia Diseases 0.000 claims 1
- 206010047281 Ventricular arrhythmia Diseases 0.000 claims 1
- 230000002159 abnormal effect Effects 0.000 claims 1
- 230000001154 acute effect Effects 0.000 claims 1
- 238000002266 amputation Methods 0.000 claims 1
- 230000001746 atrial effect Effects 0.000 claims 1
- 239000008280 blood Substances 0.000 claims 1
- 210000004369 blood Anatomy 0.000 claims 1
- 239000002775 capsule Substances 0.000 claims 1
- 208000028831 congenital heart disease Diseases 0.000 claims 1
- 230000002526 effect on cardiovascular system Effects 0.000 claims 1
- 230000001771 impaired effect Effects 0.000 claims 1
- 208000028867 ischemia Diseases 0.000 claims 1
- 208000017169 kidney disease Diseases 0.000 claims 1
- 201000006370 kidney failure Diseases 0.000 claims 1
- 208000010125 myocardial infarction Diseases 0.000 claims 1
- 230000036470 plasma concentration Effects 0.000 claims 1
- 230000000250 revascularization Effects 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US84085006P | 2006-08-28 | 2006-08-28 | |
| PCT/EP2007/007160 WO2008025450A1 (en) | 2006-08-28 | 2007-08-14 | Methods of lowering glucose levels |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010501604A JP2010501604A (ja) | 2010-01-21 |
| JP2010501604A5 true JP2010501604A5 (https=) | 2010-09-24 |
Family
ID=38578487
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009525948A Pending JP2010501604A (ja) | 2006-08-28 | 2007-08-14 | グルコースレベルを低下させる方法 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20080188538A1 (https=) |
| EP (1) | EP2059242A1 (https=) |
| JP (1) | JP2010501604A (https=) |
| KR (1) | KR20090042976A (https=) |
| CN (1) | CN101573110A (https=) |
| AU (1) | AU2007291602B2 (https=) |
| BR (1) | BRPI0716411A2 (https=) |
| CA (1) | CA2661598A1 (https=) |
| IL (1) | IL197189A0 (https=) |
| MX (1) | MX2009002091A (https=) |
| NO (1) | NO20090926L (https=) |
| WO (1) | WO2008025450A1 (https=) |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA817261B (en) * | 1980-10-23 | 1982-09-29 | Schering Corp | Carboxyalkyl dipeptides,processes for their production and pharmaceutical compositions containing them |
| DE3226768A1 (de) * | 1981-11-05 | 1983-05-26 | Hoechst Ag, 6230 Frankfurt | Derivate der cis, endo-2-azabicyclo-(3.3.0)-octan-3-carbonsaeure, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung |
| DE3413710A1 (de) * | 1984-04-12 | 1985-10-24 | Hoechst Ag, 6230 Frankfurt | Verfahren zur behandlung der herzinsuffizienz |
| DE3739690A1 (de) * | 1987-11-24 | 1989-06-08 | Hoechst Ag | Stabilisierte arzneistoffe, verfahren zu ihrer herstellung sowie stabile arzneizubereitungen |
| CA2026686A1 (en) * | 1989-10-30 | 1991-05-01 | Werner Tschollar | Method for preventing onset of type ii diabetes employing an ace inhibitor |
| SE9903028D0 (sv) * | 1999-08-27 | 1999-08-27 | Astra Ab | New use |
| PL353199A1 (en) * | 1999-08-30 | 2003-11-03 | Aventis Pharma Deutschland Gmbh | Use of inhibitors of the renin-angiotensin system in the prevention of cardiovascular events |
| IL161388A0 (en) * | 2001-10-17 | 2004-09-27 | Aventis Pharma Gmbh | Method of reducing type 2 diabetes in high risk patients |
| US20050065203A1 (en) * | 2001-10-17 | 2005-03-24 | Salim Yusuf | Method of reducing type 2 diabetes in high risk patients |
| WO2004080482A2 (en) * | 2003-03-11 | 2004-09-23 | Institut De Cardiologie De Montréal / | Use of angiotensin converting enzyme (ace) inhibitors to prevent diabetes in a subject with chronic heart failure |
-
2007
- 2007-08-14 EP EP07786675A patent/EP2059242A1/en not_active Withdrawn
- 2007-08-14 AU AU2007291602A patent/AU2007291602B2/en not_active Ceased
- 2007-08-14 JP JP2009525948A patent/JP2010501604A/ja active Pending
- 2007-08-14 WO PCT/EP2007/007160 patent/WO2008025450A1/en not_active Ceased
- 2007-08-14 MX MX2009002091A patent/MX2009002091A/es not_active Application Discontinuation
- 2007-08-14 CN CNA2007800400375A patent/CN101573110A/zh active Pending
- 2007-08-14 CA CA002661598A patent/CA2661598A1/en not_active Abandoned
- 2007-08-14 KR KR1020097005581A patent/KR20090042976A/ko not_active Ceased
- 2007-08-14 BR BRPI0716411-4A2A patent/BRPI0716411A2/pt not_active IP Right Cessation
- 2007-08-28 US US11/846,310 patent/US20080188538A1/en not_active Abandoned
-
2009
- 2009-02-23 IL IL197189A patent/IL197189A0/en unknown
- 2009-02-27 NO NO20090926A patent/NO20090926L/no not_active Application Discontinuation
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