JP2010193721A5 - - Google Patents
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- Publication number
- JP2010193721A5 JP2010193721A5 JP2009038977A JP2009038977A JP2010193721A5 JP 2010193721 A5 JP2010193721 A5 JP 2010193721A5 JP 2009038977 A JP2009038977 A JP 2009038977A JP 2009038977 A JP2009038977 A JP 2009038977A JP 2010193721 A5 JP2010193721 A5 JP 2010193721A5
- Authority
- JP
- Japan
- Prior art keywords
- cell
- cells
- induced
- comparative examples
- stem cells
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 210000004027 cell Anatomy 0.000 description 10
- 210000001789 adipocyte Anatomy 0.000 description 6
- 230000000052 comparative effect Effects 0.000 description 6
- 210000002901 mesenchymal stem cell Anatomy 0.000 description 6
- 210000001185 bone marrow Anatomy 0.000 description 5
- 230000004069 differentiation Effects 0.000 description 5
- NPGIHFRTRXVWOY-UHFFFAOYSA-N Oil red O Chemical compound Cc1ccc(C)c(c1)N=Nc1cc(C)c(cc1C)N=Nc1c(O)ccc2ccccc12 NPGIHFRTRXVWOY-UHFFFAOYSA-N 0.000 description 4
- 238000004043 dyeing Methods 0.000 description 4
- 239000001963 growth medium Substances 0.000 description 4
- 238000010186 staining Methods 0.000 description 4
- 108010076365 Adiponectin Proteins 0.000 description 2
- 239000002243 precursor Substances 0.000 description 2
- 210000000130 stem cell Anatomy 0.000 description 2
- 102000011690 Adiponectin Human genes 0.000 description 1
- 108010016731 PPAR gamma Proteins 0.000 description 1
- 238000002835 absorbance Methods 0.000 description 1
- 210000000577 adipose tissue Anatomy 0.000 description 1
- 210000002950 fibroblast Anatomy 0.000 description 1
- 239000002609 medium Substances 0.000 description 1
- 108020004999 messenger RNA Proteins 0.000 description 1
- 210000001778 pluripotent stem cell Anatomy 0.000 description 1
- WPPDXAHGCGPUPK-UHFFFAOYSA-N red 2 Chemical compound C1=CC=CC=C1C(C1=CC=CC=C11)=C(C=2C=3C4=CC=C5C6=CC=C7C8=C(C=9C=CC=CC=9)C9=CC=CC=C9C(C=9C=CC=CC=9)=C8C8=CC=C(C6=C87)C(C=35)=CC=2)C4=C1C1=CC=CC=C1 WPPDXAHGCGPUPK-UHFFFAOYSA-N 0.000 description 1
- 210000001988 somatic stem cell Anatomy 0.000 description 1
Priority Applications (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2009038977A JP5515319B2 (ja) | 2009-02-23 | 2009-02-23 | 脂肪細胞への分化誘導培地及び方法 |
| US13/202,720 US8785199B2 (en) | 2009-02-23 | 2010-02-18 | Culture medium and method for inducing differentiation into adipocytes |
| PCT/JP2010/052454 WO2010095684A1 (ja) | 2009-02-23 | 2010-02-18 | 脂肪細胞への分化誘導培地及び方法 |
| CA2753299A CA2753299C (en) | 2009-02-23 | 2010-02-18 | Culture medium and method for inducing differentiation into adipocytes |
| EP10743810.3A EP2399989B1 (en) | 2009-02-23 | 2010-02-18 | Culture medium and method for inducing differentiation into adipocytes |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2009038977A JP5515319B2 (ja) | 2009-02-23 | 2009-02-23 | 脂肪細胞への分化誘導培地及び方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010193721A JP2010193721A (ja) | 2010-09-09 |
| JP2010193721A5 true JP2010193721A5 (enExample) | 2012-04-05 |
| JP5515319B2 JP5515319B2 (ja) | 2014-06-11 |
Family
ID=42633964
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009038977A Expired - Fee Related JP5515319B2 (ja) | 2009-02-23 | 2009-02-23 | 脂肪細胞への分化誘導培地及び方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US8785199B2 (enExample) |
| EP (1) | EP2399989B1 (enExample) |
| JP (1) | JP5515319B2 (enExample) |
| CA (1) | CA2753299C (enExample) |
| WO (1) | WO2010095684A1 (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5663841B2 (ja) * | 2009-02-23 | 2015-02-04 | 富士レビオ株式会社 | 骨細胞への分化誘導培地及び方法 |
| WO2013173688A1 (en) * | 2012-05-18 | 2013-11-21 | The Cooper Health System | A method of making tissue engineered blood vessels and generating capillary networks, articles, and methods of use thereof |
| US12161688B2 (en) | 2016-06-30 | 2024-12-10 | Mapi Pharma Ltd | Treatment of inflammatory bowel disease with long acting glatiramer and adipose-derived stem cells |
| KR101877793B1 (ko) * | 2016-07-15 | 2018-07-13 | 주식회사 엔바이오텍 | 줄기세포 배양용 무혈청 배지 조성물 및 이를 이용한 줄기세포의 배양 방법 |
| CN108130310A (zh) * | 2016-11-30 | 2018-06-08 | 江阴瑞康健生物医学科技有限公司 | 一种干细胞培养基 |
| AU2018270396B2 (en) | 2017-05-15 | 2025-03-20 | Stem Cell Medicine Ltd. | Treatment of multiple sclerosis with adipose-derived stem cells |
| WO2018211486A1 (en) | 2017-05-15 | 2018-11-22 | Stem Cell Medicine Ltd. | Treatment of multiple sclerosis with long acting glatiramer and adipose-derived stem cells |
| CN110257324A (zh) * | 2019-07-24 | 2019-09-20 | 安徽科门生物科技有限公司 | 一种用于脂肪间充质干细胞成脂诱导的培养基以及诱导方法 |
| CN113337457B (zh) * | 2021-06-01 | 2024-06-25 | 澳门大学 | 一种无血清调控干细胞的细胞状态的方法以及调节剂的应用 |
| CN115927172A (zh) * | 2022-12-15 | 2023-04-07 | 南京周子未来食品科技有限公司 | 一种诱导体外成脂分化的化学成分明确的改良培养基及其应用 |
| CN116162587B (zh) * | 2023-02-20 | 2025-07-25 | 杭州瑞普晨创科技有限公司 | Hippo-Yap通路调控剂在促进诱导性多能干细胞向胰腺前体细胞定向分化中的应用 |
| CN119842599B (zh) * | 2025-03-21 | 2025-07-22 | 中国海洋大学 | 一种鱼类干细胞无血清诱导成脂分化培养基及其应用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003084468A2 (en) * | 2002-04-03 | 2003-10-16 | Artecel Sciences, Inc. | Improvements of adipocytic differentiated adipose derived adult stem cells and uses thereof |
| WO2006097682A1 (en) * | 2005-03-18 | 2006-09-21 | Ucl Business Plc | Mechano growth factor peptides and their use |
| EP2233565B1 (en) * | 2007-12-28 | 2015-05-13 | Fujirebio Inc. | Medium for mammalian somatic cells and additive therefor |
-
2009
- 2009-02-23 JP JP2009038977A patent/JP5515319B2/ja not_active Expired - Fee Related
-
2010
- 2010-02-18 US US13/202,720 patent/US8785199B2/en not_active Expired - Fee Related
- 2010-02-18 EP EP10743810.3A patent/EP2399989B1/en not_active Not-in-force
- 2010-02-18 WO PCT/JP2010/052454 patent/WO2010095684A1/ja not_active Ceased
- 2010-02-18 CA CA2753299A patent/CA2753299C/en not_active Expired - Fee Related
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