JP2019004903A5 - - Google Patents
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- Publication number
- JP2019004903A5 JP2019004903A5 JP2018167419A JP2018167419A JP2019004903A5 JP 2019004903 A5 JP2019004903 A5 JP 2019004903A5 JP 2018167419 A JP2018167419 A JP 2018167419A JP 2018167419 A JP2018167419 A JP 2018167419A JP 2019004903 A5 JP2019004903 A5 JP 2019004903A5
- Authority
- JP
- Japan
- Prior art keywords
- cell population
- lineage
- cell
- cells
- activator
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 210000004027 cell Anatomy 0.000 claims 26
- 230000004156 Wnt signaling pathway Effects 0.000 claims 5
- 239000012190 activator Substances 0.000 claims 5
- 210000003716 mesoderm Anatomy 0.000 claims 5
- 210000000130 stem cell Anatomy 0.000 claims 5
- 239000001963 growth medium Substances 0.000 claims 4
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 claims 3
- 239000000090 biomarker Substances 0.000 claims 3
- 210000001789 adipocyte Anatomy 0.000 claims 2
- 210000000988 bone and bone Anatomy 0.000 claims 2
- 210000000845 cartilage Anatomy 0.000 claims 2
- 239000013000 chemical inhibitor Substances 0.000 claims 2
- 238000012258 culturing Methods 0.000 claims 2
- 210000002889 endothelial cell Anatomy 0.000 claims 2
- KWGKDLIKAYFUFQ-UHFFFAOYSA-M lithium chloride Chemical group [Li+].[Cl-] KWGKDLIKAYFUFQ-UHFFFAOYSA-M 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- 230000011664 signaling Effects 0.000 claims 2
- 210000002027 skeletal muscle Anatomy 0.000 claims 2
- 210000004927 skin cell Anatomy 0.000 claims 2
- AQGNHMOJWBZFQQ-UHFFFAOYSA-N CT 99021 Chemical group CC1=CNC(C=2C(=NC(NCCNC=3N=CC(=CC=3)C#N)=NC=2)C=2C(=CC(Cl)=CC=2)Cl)=N1 AQGNHMOJWBZFQQ-UHFFFAOYSA-N 0.000 claims 1
- 102000019058 Glycogen Synthase Kinase 3 beta Human genes 0.000 claims 1
- 108010051975 Glycogen Synthase Kinase 3 beta Proteins 0.000 claims 1
- 101150026534 Msgn1 gene Proteins 0.000 claims 1
- 102000004887 Transforming Growth Factor beta Human genes 0.000 claims 1
- 108090001012 Transforming Growth Factor beta Proteins 0.000 claims 1
- XHBVYDAKJHETMP-UHFFFAOYSA-N dorsomorphin Chemical compound C=1C=C(C2=CN3N=CC(=C3N=C2)C=2C=CN=CC=2)C=CC=1OCCN1CCCCC1 XHBVYDAKJHETMP-UHFFFAOYSA-N 0.000 claims 1
- 210000001671 embryonic stem cell Anatomy 0.000 claims 1
- 239000003112 inhibitor Substances 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
Applications Claiming Priority (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161528348P | 2011-08-29 | 2011-08-29 | |
| EP11306080.0 | 2011-08-29 | ||
| US61/528,348 | 2011-08-29 | ||
| EP11306080A EP2565264A1 (en) | 2011-08-29 | 2011-08-29 | Method for preparing induced paraxial mesoderm progenitor (iPAM) cells and their use |
| US201261654120P | 2012-06-01 | 2012-06-01 | |
| EP12305610 | 2012-06-01 | ||
| US61/654,120 | 2012-06-01 | ||
| EP12305610.3 | 2012-06-01 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014527647A Division JP6570833B2 (ja) | 2011-08-29 | 2012-08-29 | 人工沿軸中胚葉前駆（ｉＰＡＭ）細胞を調製する方法及びその使用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2019004903A JP2019004903A (ja) | 2019-01-17 |
| JP2019004903A5 true JP2019004903A5 (enExample) | 2019-03-28 |
Family
ID=50690361
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018167419A Pending JP2019004903A (ja) | 2011-08-29 | 2018-09-07 | 人工沿軸中胚葉前駆（ｉＰＡＭ）細胞を調製する方法及びその使用 |
Country Status (2)
| Country | Link |
|---|---|
| JP (1) | JP2019004903A (enExample) |
| IL (1) | IL231205B (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2022094628A2 (en) * | 2020-11-02 | 2022-05-05 | Conception Biosciences, Inc. | In vitro derivation of gonadal somatic cells |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20080038820A1 (en) * | 2004-06-22 | 2008-02-14 | Rudy-Reil Diane E | Induction of pluripotent stem cells into mesodermal lineages |
| KR101193541B1 (ko) * | 2009-08-24 | 2012-10-22 | 한국과학기술원 | 인간 배아줄기세포에서 중간엽 줄기세포로 분화시키는 방법 |
| CN103733096B (zh) * | 2011-08-19 | 2017-06-23 | Lg化学株式会社 | 偏光板 |
-
2014
- 2014-02-27 IL IL231205A patent/IL231205B/en active IP Right Grant
-
2018
- 2018-09-07 JP JP2018167419A patent/JP2019004903A/ja active Pending
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