JP2010142226A5 - - Google Patents
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- JP2010142226A5 JP2010142226A5 JP2009285970A JP2009285970A JP2010142226A5 JP 2010142226 A5 JP2010142226 A5 JP 2010142226A5 JP 2009285970 A JP2009285970 A JP 2009285970A JP 2009285970 A JP2009285970 A JP 2009285970A JP 2010142226 A5 JP2010142226 A5 JP 2010142226A5
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- JP
- Japan
- Prior art keywords
- seq
- polypeptide
- acid sequence
- amino acid
- positions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 108090000765 processed proteins & peptides Proteins 0.000 claims 52
- 229920001184 polypeptide Polymers 0.000 claims 51
- 102000004196 processed proteins & peptides Human genes 0.000 claims 51
- 125000003275 alpha amino acid group Chemical group 0.000 claims 39
- 239000008194 pharmaceutical composition Substances 0.000 claims 18
- 239000012634 fragment Substances 0.000 claims 17
- 230000002163 immunogen Effects 0.000 claims 17
- 239000002157 polynucleotide Substances 0.000 claims 12
- 102000040430 polynucleotide Human genes 0.000 claims 12
- 108091033319 polynucleotide Proteins 0.000 claims 12
- 150000001413 amino acids Chemical class 0.000 claims 6
- 230000028993 immune response Effects 0.000 claims 6
- 239000000758 substrate Substances 0.000 claims 6
- 239000007787 solid Substances 0.000 claims 5
- 208000004554 Leishmaniasis Diseases 0.000 claims 4
- 239000003814 drug Substances 0.000 claims 3
- 238000000034 method Methods 0.000 claims 3
- 241000607117 Phlebotomus ariasi Species 0.000 claims 2
- 241000722340 Phlebotomus perniciosus Species 0.000 claims 2
- 230000005867 T cell response Effects 0.000 claims 2
- 239000002671 adjuvant Substances 0.000 claims 2
- 210000003719 b-lymphocyte Anatomy 0.000 claims 2
- 230000036755 cellular response Effects 0.000 claims 2
- 230000001939 inductive effect Effects 0.000 claims 2
- 230000002401 inhibitory effect Effects 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 239000000203 mixture Substances 0.000 claims 2
- 239000002773 nucleotide Substances 0.000 claims 2
- 125000003729 nucleotide group Chemical group 0.000 claims 2
- 208000024891 symptom Diseases 0.000 claims 2
- 241000222722 Leishmania <genus> Species 0.000 claims 1
- 241000255129 Phlebotominae Species 0.000 claims 1
- 239000004793 Polystyrene Substances 0.000 claims 1
- 239000012491 analyte Substances 0.000 claims 1
- 239000011324 bead Substances 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 238000001514 detection method Methods 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 239000012528 membrane Substances 0.000 claims 1
- 229920002223 polystyrene Polymers 0.000 claims 1
- 210000003296 saliva Anatomy 0.000 claims 1
- 150000007523 nucleic acids Chemical class 0.000 description 70
- 102000004169 proteins and genes Human genes 0.000 description 70
- 108090000623 proteins and genes Proteins 0.000 description 70
- 108020004707 nucleic acids Proteins 0.000 description 35
- 102000039446 nucleic acids Human genes 0.000 description 35
- 108091028043 Nucleic acid sequence Proteins 0.000 description 16
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 description 2
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US42230302P | 2002-10-29 | 2002-10-29 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004548595A Division JP2006516187A (ja) | 2002-10-29 | 2003-10-29 | ルツォーミアロンギパルピスポリペプチドおよび使用方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010142226A JP2010142226A (ja) | 2010-07-01 |
| JP2010142226A5 true JP2010142226A5 (cg-RX-API-DMAC7.html) | 2010-10-07 |
Family
ID=32230337
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004548595A Pending JP2006516187A (ja) | 2002-10-29 | 2003-10-29 | ルツォーミアロンギパルピスポリペプチドおよび使用方法 |
| JP2009285970A Withdrawn JP2010142226A (ja) | 2002-10-29 | 2009-12-17 | ルツォーミアロンギパルピスポリペプチドおよび使用方法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004548595A Pending JP2006516187A (ja) | 2002-10-29 | 2003-10-29 | ルツォーミアロンギパルピスポリペプチドおよび使用方法 |
Country Status (10)
| Country | Link |
|---|---|
| US (6) | US7485306B2 (cg-RX-API-DMAC7.html) |
| EP (2) | EP2085467B1 (cg-RX-API-DMAC7.html) |
| JP (2) | JP2006516187A (cg-RX-API-DMAC7.html) |
| AT (1) | ATE429487T1 (cg-RX-API-DMAC7.html) |
| AU (1) | AU2003287267A1 (cg-RX-API-DMAC7.html) |
| BR (1) | BR0315872A (cg-RX-API-DMAC7.html) |
| DE (1) | DE60327366D1 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2447843T3 (cg-RX-API-DMAC7.html) |
| MX (1) | MXPA05004714A (cg-RX-API-DMAC7.html) |
| WO (1) | WO2004039958A2 (cg-RX-API-DMAC7.html) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1545575A4 (en) | 2002-09-19 | 2006-04-05 | Us Gov Health & Human Serv | P. ARIASI POLYPEPTIDE, P. PERNICIOSUS POLYPEPTIDES AND METHOD OF USE |
| JP2006516187A (ja) * | 2002-10-29 | 2006-06-29 | アメリカ合衆国 | ルツォーミアロンギパルピスポリペプチドおよび使用方法 |
| US8968749B2 (en) | 2006-07-21 | 2015-03-03 | Universidade Federal De Minas Gerais—Ufmg | Vaccine composition and immunization method |
| BRPI0603490B1 (pt) * | 2006-07-21 | 2018-04-24 | Universidade Federal De Minas Gerais | Vacina recombinante contra a leishmaniose visceral canina |
| GB0717864D0 (en) * | 2007-09-13 | 2007-10-24 | Peptcell Ltd | Peptide sequences and compositions |
| BRPI0915605B8 (pt) * | 2008-05-08 | 2021-09-08 | The Government Of The Us Secretary Of The Dept Of Healt & Human Services | Vacina de leishmania usando imunógeno salivar de mosca tipo borrachudo |
| WO2010021940A1 (en) * | 2008-08-18 | 2010-02-25 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Insect proteins as adjuvants to accelerate the immune response |
| JP5590986B2 (ja) | 2010-06-23 | 2014-09-17 | 株式会社シマノ | 釣り用リールのワンウェイクラッチ |
| AR111842A1 (es) | 2017-06-02 | 2019-08-21 | Amgen Inc | Antagonistas de péptido pac1 |
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| US2909462A (en) | 1955-12-08 | 1959-10-20 | Bristol Myers Co | Acrylic acid polymer laxative compositions |
| US4036945A (en) | 1976-05-03 | 1977-07-19 | The Massachusetts General Hospital | Composition and method for determining the size and location of myocardial infarcts |
| US4444487A (en) | 1979-07-02 | 1984-04-24 | Xerox Corporation | Multiple-flash fuser |
| US4331647A (en) | 1980-03-03 | 1982-05-25 | Goldenberg Milton David | Tumor localization and therapy with labeled antibody fragments specific to tumor-associated markers |
| US4722848A (en) | 1982-12-08 | 1988-02-02 | Health Research, Incorporated | Method for immunizing animals with synthetically modified vaccinia virus |
| US4603112A (en) | 1981-12-24 | 1986-07-29 | Health Research, Incorporated | Modified vaccinia virus |
| GB8308235D0 (en) | 1983-03-25 | 1983-05-05 | Celltech Ltd | Polypeptides |
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US4745051A (en) | 1983-05-27 | 1988-05-17 | The Texas A&M University System | Method for producing a recombinant baculovirus expression vector |
| DE3584341D1 (de) | 1984-08-24 | 1991-11-14 | Upjohn Co | Rekombinante dna-verbindungen und expression von polypeptiden wie tpa. |
| US4745055A (en) | 1985-05-07 | 1988-05-17 | California Biotechnology Inc. | Fused protein for enzyme immunoassay system |
| ATE143052T1 (de) | 1986-07-07 | 1996-10-15 | Centocor Inc | Chimärisches murine-mensch-immunoglobulin, spezifisch für tumorassoziertes 17-1a antigen |
| US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
| NZ221790A (en) | 1986-09-12 | 1990-07-26 | Genentech Inc | Method for the continuous production of a heterologous protein in a eukaryotic host cell |
| IL84154A0 (en) | 1986-10-16 | 1988-03-31 | Microgenesys Inc | Polypeptides derived from the envelope gene of human immunodeficiency virus in recombinant baculovirus infected insect cells and vaccines against acquired immune deficiency syndrome containing the same |
| GB8626412D0 (en) | 1986-11-05 | 1986-12-03 | Clark M R | Antibodies |
| GB8717430D0 (en) | 1987-07-23 | 1987-08-26 | Celltech Ltd | Recombinant dna product |
| CA1323293C (en) | 1987-12-11 | 1993-10-19 | Keith C. Backman | Assay using template-dependent nucleic acid probe reorganization |
| DE3743138A1 (de) | 1987-12-18 | 1989-09-14 | Mayr Christian Gmbh & Co Kg | Schleifringlose, elektromagnetische ueberlastkupplung |
| JP2955759B2 (ja) | 1988-07-20 | 1999-10-04 | セゲブ・ダイアグノスティックス・インコーポレイテッド | 核酸配列を増幅及び検出する方法 |
| CA2003300A1 (en) | 1988-11-21 | 1990-05-21 | Franklin Volvovitz | Skin test and test kit for aids |
| US5703055A (en) | 1989-03-21 | 1997-12-30 | Wisconsin Alumni Research Foundation | Generation of antibodies through lipid mediated DNA delivery |
| US5397772A (en) * | 1989-06-29 | 1995-03-14 | The President And Fellows Of Harvard College | Vasodilatory peptides from the salivary gland of the sand fly Lutzomyia longipalpis |
| US5270202A (en) | 1989-11-03 | 1993-12-14 | Syamal Raychaudhuri | Anti-idiotypic antibodies to human melanoma-associated proteoglycan antigen |
| US5427930A (en) | 1990-01-26 | 1995-06-27 | Abbott Laboratories | Amplification of target nucleic acids using gap filling ligase chain reaction |
| DE69030172T2 (de) | 1990-01-26 | 1997-06-19 | Immunomedics Inc | Impfstoffe gegen Krebs und Infektionskrankheiten |
| JP3602530B2 (ja) | 1991-03-07 | 2004-12-15 | ヴァイロジェネティクス コーポレイション | 遺伝子操作したワクチン菌株 |
| US5709860A (en) | 1991-07-25 | 1998-01-20 | Idec Pharmaceuticals Corporation | Induction of cytotoxic T-lymphocyte responses |
| US5585103A (en) | 1991-07-25 | 1996-12-17 | Idec Pharmaceutical Corporation | Induction of cytotoxic T-lymphocyte responses |
| US5643578A (en) | 1992-03-23 | 1997-07-01 | University Of Massachusetts Medical Center | Immunization by inoculation of DNA transcription unit |
| US5662907A (en) | 1992-08-07 | 1997-09-02 | Cytel Corporation | Induction of anti-tumor cytotoxic T lymphocytes in humans using synthetic peptide epitopes |
| CA2142007C (en) | 1992-08-11 | 2007-10-30 | Robert Glen Urban | Immunomodulatory peptides |
| US5593972A (en) | 1993-01-26 | 1997-01-14 | The Wistar Institute | Genetic immunization |
| ES2198420T3 (es) | 1993-09-03 | 2004-02-01 | Mcgill University | Genes y proteinas de (leishmania) expresados diferencialmente. |
| FR2712603B1 (fr) | 1993-11-18 | 1996-02-09 | Centre Nat Rech Scient | Virus recombinants, préparation et utilisation en thérapie génique. |
| US5529780A (en) | 1994-03-30 | 1996-06-25 | Virogenetics Corporation | Nucleotide and amino acid sequences of canine herpesvirus gB and gC |
| US5648211A (en) | 1994-04-18 | 1997-07-15 | Becton, Dickinson And Company | Strand displacement amplification using thermophilic enzymes |
| DK0776376T3 (da) | 1994-07-15 | 2002-02-18 | Organon Teknika Bv | Anvendelse af RNA-polymerase til forbedring af en nucleinsyreamplifikationsproces |
| CA2214029A1 (en) | 1995-04-25 | 1996-10-31 | Magda Marquet | Single-vial formulations of dna/lipid complexes |
| AT402203B (de) | 1995-06-13 | 1997-03-25 | Himmler Gottfried Dipl Ing Dr | Verfahren zur transkriptionsfreien amplifizierung von nucleinsäuren |
| EP0803573A1 (en) | 1996-04-25 | 1997-10-29 | Gesellschaft für Biotechnologische Forschung mbH (GBF) | Polycistronic expression construct with cytokines for multivalent vaccines |
| FR2750865B1 (fr) | 1996-06-27 | 1998-12-04 | Rhone Merieux | Vaccin vivant recombinant a base d'herpesvirus canin, notamment contre la maladie de carre, la rage ou le virus parainfluenza de type 2 |
| US6156567A (en) | 1996-07-03 | 2000-12-05 | Merial | Truncated transcriptionally active cytomegalovirus promoters |
| US6090393A (en) | 1996-07-03 | 2000-07-18 | Merial | Recombinant canine adenoviruses, method for making and uses thereof |
| DE69740033D1 (de) | 1996-07-03 | 2010-12-09 | Merial Inc | Rekombinanter hunde-adenovirus 2 (cav2), welcher exogene dna enthält |
| CA2268825C (en) | 1996-10-11 | 2006-04-18 | The Regents Of The University Of California | Immunostimulatory polynucleotide/immunomodulatory molecule conjugates |
| US6017537A (en) | 1998-12-18 | 2000-01-25 | Connaught Laboratories, Inc. | Formyl methionyl peptide vaccine adjuvant |
| US6645740B1 (en) | 1999-06-10 | 2003-11-11 | Merial Limited | Nucleic acids encodings equine GM-CSF |
| MXPA04000057A (es) | 2001-06-19 | 2005-01-07 | Gov Health & Human Serv | Vacunas de vector anti-artropodo, metodos de seleccion y usos de las mismas. |
| EP1545575A4 (en) | 2002-09-19 | 2006-04-05 | Us Gov Health & Human Serv | P. ARIASI POLYPEPTIDE, P. PERNICIOSUS POLYPEPTIDES AND METHOD OF USE |
| JP2006516187A (ja) * | 2002-10-29 | 2006-06-29 | アメリカ合衆国 | ルツォーミアロンギパルピスポリペプチドおよび使用方法 |
-
2003
- 2003-10-29 JP JP2004548595A patent/JP2006516187A/ja active Pending
- 2003-10-29 BR BRPI0315872-1A patent/BR0315872A/pt not_active Application Discontinuation
- 2003-10-29 DE DE60327366T patent/DE60327366D1/de not_active Expired - Lifetime
- 2003-10-29 WO PCT/US2003/034453 patent/WO2004039958A2/en not_active Ceased
- 2003-10-29 EP EP20090158294 patent/EP2085467B1/en not_active Expired - Lifetime
- 2003-10-29 US US10/533,811 patent/US7485306B2/en not_active Expired - Lifetime
- 2003-10-29 MX MXPA05004714A patent/MXPA05004714A/es active IP Right Grant
- 2003-10-29 ES ES09158294T patent/ES2447843T3/es not_active Expired - Lifetime
- 2003-10-29 AU AU2003287267A patent/AU2003287267A1/en not_active Abandoned
- 2003-10-29 AT AT03781500T patent/ATE429487T1/de not_active IP Right Cessation
- 2003-10-29 EP EP03781500A patent/EP1572968B1/en not_active Expired - Lifetime
-
2009
- 2009-01-07 US US12/350,179 patent/US8628780B2/en not_active Expired - Lifetime
- 2009-12-17 JP JP2009285970A patent/JP2010142226A/ja not_active Withdrawn
-
2013
- 2013-12-05 US US14/097,991 patent/US9120867B2/en not_active Expired - Lifetime
-
2015
- 2015-07-17 US US14/802,168 patent/US9382302B2/en not_active Expired - Fee Related
-
2016
- 2016-06-07 US US15/175,329 patent/US9884100B2/en not_active Expired - Lifetime
-
2018
- 2018-01-09 US US15/866,050 patent/US10314900B2/en not_active Expired - Lifetime