JP2009544718A5 - - Google Patents
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- Publication number
- JP2009544718A5 JP2009544718A5 JP2009521907A JP2009521907A JP2009544718A5 JP 2009544718 A5 JP2009544718 A5 JP 2009544718A5 JP 2009521907 A JP2009521907 A JP 2009521907A JP 2009521907 A JP2009521907 A JP 2009521907A JP 2009544718 A5 JP2009544718 A5 JP 2009544718A5
- Authority
- JP
- Japan
- Prior art keywords
- cell adhesion
- pharmaceutical composition
- sequence
- filamentous bacteriophage
- therapeutic agent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US83222906P | 2006-07-21 | 2006-07-21 | |
| PCT/US2007/073858 WO2008011503A2 (en) | 2006-07-21 | 2007-07-19 | Use of a phage displaying a peptide from an adhesion protein for treating a disease associated with intracellular formation of protein fibrillar inclusions or aggregates |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009544718A JP2009544718A (ja) | 2009-12-17 |
| JP2009544718A5 true JP2009544718A5 (https=) | 2010-07-29 |
Family
ID=38957610
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009521907A Pending JP2009544718A (ja) | 2006-07-21 | 2007-07-19 | タンパク質の繊維性封入体または凝集体の細胞内形成に関連する疾患を処置するための接着タンパク質からのペプチドをディスプレイするファージの使用 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20090324554A1 (https=) |
| EP (1) | EP2054515B1 (https=) |
| JP (1) | JP2009544718A (https=) |
| CN (1) | CN101553567A (https=) |
| AT (1) | ATE541038T1 (https=) |
| AU (1) | AU2007275258A1 (https=) |
| CA (1) | CA2659032A1 (https=) |
| WO (1) | WO2008011503A2 (https=) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009072578A1 (ja) * | 2007-12-04 | 2009-06-11 | Sapporo Breweries Limited | 骨吸収抑制剤 |
| EP2303315A1 (en) * | 2008-05-22 | 2011-04-06 | Ramot at Tel Aviv University Ltd. | Method for treating disease characterized by plaque |
| NZ592928A (en) * | 2008-11-24 | 2012-12-21 | Univ Ramot | Method for treating parkinson' s disease using filamentous bacteriophage |
| WO2012125555A1 (en) | 2011-03-11 | 2012-09-20 | Ramot At Tel-Aviv University Ltd. | Method for treating neurodegenerative tauopathy |
| WO2012142622A1 (en) * | 2011-04-15 | 2012-10-18 | Molecular Transfer, Inc. | Agents for improved delivery of nucleic acids to eukaryotic cells |
| EP2736522A1 (en) | 2011-07-27 | 2014-06-04 | Neurophage Pharmaceuticals, Inc. | Process for the production of filamentous bacteriophage |
| WO2013022717A1 (en) | 2011-08-05 | 2013-02-14 | Neurophage Pharmaceuticals, Inc. | Pure filamentous bacteriophage and methods of producing same |
| CA2857539C (en) | 2011-11-29 | 2021-08-03 | Neurophage Pharmaceuticals, Inc. | Bacteriophage gene 3 protein compositions and use as amyloid binding agents |
| DK2906235T3 (en) | 2012-10-02 | 2017-09-25 | Proclara Biosciences Inc | USE OF P3 OF BACTERIOPHAGIC FUSION PROTEINS AS AMYLOID BINDING AGENTS |
| AU2014274253B2 (en) | 2013-05-28 | 2018-06-14 | Proclara Biosciences, Inc. | Polypeptides comprising a modified bacteriophage g3p amino acid sequence with reduced immunogenicity |
| CN104258372B (zh) * | 2014-09-25 | 2017-01-25 | 中山大学 | Rgd三肽在制备治疗阿尔茨海默症药物中的用途 |
| BR112017011530A2 (pt) | 2014-12-03 | 2018-03-13 | Proclara Biosciences Inc | polipeptídeos que compreendem uma sequência de aminoácidos g3p de bacteriófago modificada sem sinal de glicosilação |
| CN106800590B (zh) * | 2015-11-25 | 2021-04-09 | 杭州智鹤丹谷生物医药有限公司 | 一种结合多种淀粉样蛋白单体和聚集体的多肽及其应用 |
| WO2018215831A2 (en) * | 2017-05-22 | 2018-11-29 | National Hellenic Research Foundation | Macrocyclic modulators of disease associated protein misfolding and aggregation |
| CA3076473A1 (en) * | 2017-09-20 | 2019-03-28 | Council Of Scientific And Industrial Research | Novel peptide as potent inhibitor of protein aggregation |
| WO2022073127A1 (en) * | 2020-10-07 | 2022-04-14 | Tatum Bioscience Inc. | Live biotherapeutics secreting synthetic bacteriophages in the treatment of cancer |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU784568B2 (en) * | 1999-09-03 | 2006-05-04 | Ramot At Tel-Aviv University Ltd | Agents and compositions and methods utilizing same useful in diagnosing and/or treating or preventing plaque forming diseases |
| US20040013647A1 (en) * | 1999-09-03 | 2004-01-22 | Ramot At Tel-Aviv University Ltd. | Methods and compositions for treating a plaque-forming disease |
| WO2003076455A2 (en) * | 2002-03-05 | 2003-09-18 | Ramot At Tel-Aviv University Ltd. | Immunizing composition and method for inducing an immune response against the ss-secretase cleavage site of amyloid precursor protein |
| WO2006050041A2 (en) * | 2004-10-28 | 2006-05-11 | Ramot At Tel Aviv University Ltd. | Methods for reducing or inhibiting brain inflammation or for promoting neurogenesis |
| DK1853285T3 (da) * | 2005-02-01 | 2011-06-27 | Univ Ramot | Fremgangsmåde til behandling af inflammation forbundet med amyloidaflejringer og hjerneinflammation som involverer aktiverede mikroglia |
| WO2006100681A2 (en) * | 2005-03-25 | 2006-09-28 | Ramot At Tel Aviv University Ltd. | Human synthetic single-chain antibodies directed against the common epitope of mutant p53 and their uses |
-
2007
- 2007-07-19 AU AU2007275258A patent/AU2007275258A1/en not_active Abandoned
- 2007-07-19 EP EP07799710A patent/EP2054515B1/en not_active Not-in-force
- 2007-07-19 US US12/374,594 patent/US20090324554A1/en not_active Abandoned
- 2007-07-19 JP JP2009521907A patent/JP2009544718A/ja active Pending
- 2007-07-19 CN CNA2007800349538A patent/CN101553567A/zh active Pending
- 2007-07-19 AT AT07799710T patent/ATE541038T1/de active
- 2007-07-19 WO PCT/US2007/073858 patent/WO2008011503A2/en not_active Ceased
- 2007-07-19 CA CA002659032A patent/CA2659032A1/en not_active Abandoned
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