JP2009544718A5 - - Google Patents
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- Publication number
- JP2009544718A5 JP2009544718A5 JP2009521907A JP2009521907A JP2009544718A5 JP 2009544718 A5 JP2009544718 A5 JP 2009544718A5 JP 2009521907 A JP2009521907 A JP 2009521907A JP 2009521907 A JP2009521907 A JP 2009521907A JP 2009544718 A5 JP2009544718 A5 JP 2009544718A5
- Authority
- JP
- Japan
- Prior art keywords
- cell adhesion
- pharmaceutical composition
- sequence
- filamentous bacteriophage
- therapeutic agent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US83222906P | 2006-07-21 | 2006-07-21 | |
| PCT/US2007/073858 WO2008011503A2 (en) | 2006-07-21 | 2007-07-19 | Use of a phage displaying a peptide from an adhesion protein for treating a disease associated with intracellular formation of protein fibrillar inclusions or aggregates |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009544718A JP2009544718A (ja) | 2009-12-17 |
| JP2009544718A5 true JP2009544718A5 (https=) | 2010-07-29 |
Family
ID=38957610
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009521907A Pending JP2009544718A (ja) | 2006-07-21 | 2007-07-19 | タンパク質の繊維性封入体または凝集体の細胞内形成に関連する疾患を処置するための接着タンパク質からのペプチドをディスプレイするファージの使用 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20090324554A1 (https=) |
| EP (1) | EP2054515B1 (https=) |
| JP (1) | JP2009544718A (https=) |
| CN (1) | CN101553567A (https=) |
| AT (1) | ATE541038T1 (https=) |
| AU (1) | AU2007275258A1 (https=) |
| CA (1) | CA2659032A1 (https=) |
| WO (1) | WO2008011503A2 (https=) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5214632B2 (ja) * | 2007-12-04 | 2013-06-19 | サッポロビール株式会社 | 骨吸収抑制剤 |
| WO2009143470A1 (en) | 2008-05-22 | 2009-11-26 | Ramot At Tel Aviv University Ltd. | Method for treating disease characterized by plaque |
| RU2011125971A (ru) * | 2008-11-24 | 2012-12-27 | Рамот Эт Тель-Авив Юниверсити Лтд. | Способ лечения болезни паркинсона |
| BR112013023040A2 (pt) * | 2011-03-11 | 2018-10-23 | Univ Ramot | bacteriófago filamentoso, composição farmacêutica, e, métodos para reduzir a formação de fibrilas de proteína tau ou para desagregar fibrilas pré-formadas de proteína tau em um paciente, e para tratar uma tauopatia degenerativa. |
| AU2012242455A1 (en) * | 2011-04-15 | 2013-11-28 | Molecular Transfer, Inc. | Agents for improved delivery of nucleic acids to eukaryotic cells |
| WO2013016644A1 (en) | 2011-07-27 | 2013-01-31 | Neurophage Pharmaceuticals, Inc. | Process for the production of filamentous bacteriophage |
| WO2013022717A1 (en) | 2011-08-05 | 2013-02-14 | Neurophage Pharmaceuticals, Inc. | Pure filamentous bacteriophage and methods of producing same |
| CN114748605A (zh) | 2011-11-29 | 2022-07-15 | 普罗克拉拉生物科学股份有限公司 | 噬菌体基因3蛋白组合物及作为淀粉样蛋白结合剂的用途 |
| CN104870008B (zh) | 2012-10-02 | 2019-10-01 | 普罗克拉拉生物科学股份有限公司 | 噬菌体的p3融合蛋白作为淀粉样蛋白结合剂的用途 |
| KR20160010618A (ko) | 2013-05-28 | 2016-01-27 | 뉴로페이지 파마슈티컬즈, 인크. | 감소된 면역원성을 갖는 개질된 박테리오파아지 g3p 아미노산 서열을 포함하는 폴리펩티드 |
| CN104258372B (zh) * | 2014-09-25 | 2017-01-25 | 中山大学 | Rgd三肽在制备治疗阿尔茨海默症药物中的用途 |
| PL3227313T3 (pl) | 2014-12-03 | 2022-05-09 | Proclara Biosciences, Inc. | Polipeptydy zawierające zmodyfikowaną sekwencję aminokwasową bakteriofaga g3p pozbawioną sygnału glikozylacji |
| CN106800590B (zh) * | 2015-11-25 | 2021-04-09 | 杭州智鹤丹谷生物医药有限公司 | 一种结合多种淀粉样蛋白单体和聚集体的多肽及其应用 |
| WO2018215831A2 (en) * | 2017-05-22 | 2018-11-29 | National Hellenic Research Foundation | Macrocyclic modulators of disease associated protein misfolding and aggregation |
| EP3684784B1 (en) * | 2017-09-20 | 2024-03-27 | Council of Scientific and Industrial Research | Potent peptide inhibitors of protein aggregation |
| US20230372419A1 (en) * | 2020-10-07 | 2023-11-23 | Tatum Bioscience Inc. | Live biotherapeutics secreting synthetic bacteriophages in the treatment of cancer |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2003509020A (ja) * | 1999-09-03 | 2003-03-11 | ラモット・ユニバーシティ・オーソリティ・フォー・アプライド・リサーチ・アンド・インダストリアル・ディベロップメント・リミテッド | プラーク形成疾患の診断、治療、予防に有用な薬剤、組成物、その使用法 |
| US20040013647A1 (en) * | 1999-09-03 | 2004-01-22 | Ramot At Tel-Aviv University Ltd. | Methods and compositions for treating a plaque-forming disease |
| CA2477675C (en) * | 2002-03-05 | 2013-05-21 | Ramot At Tel-Aviv University Ltd. | Immunizing composition and method for inducing an immune response against the .beta.-secretase cleavage site of amyloid precursor protein |
| WO2006050041A2 (en) * | 2004-10-28 | 2006-05-11 | Ramot At Tel Aviv University Ltd. | Methods for reducing or inhibiting brain inflammation or for promoting neurogenesis |
| EP1853285B1 (en) * | 2005-02-01 | 2011-03-16 | Ramot at Tel-Aviv University Ltd. | Method for treating inflammation associated with amyloid deposits and brain inflammation involving activated microglia |
| EP1863846B1 (en) * | 2005-03-25 | 2009-07-22 | Ramot at Tel-Aviv University Ltd. | Human synthetic single-chain antibodies directed against the common epitope of mutant p53 and their uses |
-
2007
- 2007-07-19 EP EP07799710A patent/EP2054515B1/en not_active Not-in-force
- 2007-07-19 JP JP2009521907A patent/JP2009544718A/ja active Pending
- 2007-07-19 AT AT07799710T patent/ATE541038T1/de active
- 2007-07-19 AU AU2007275258A patent/AU2007275258A1/en not_active Abandoned
- 2007-07-19 US US12/374,594 patent/US20090324554A1/en not_active Abandoned
- 2007-07-19 WO PCT/US2007/073858 patent/WO2008011503A2/en not_active Ceased
- 2007-07-19 CN CNA2007800349538A patent/CN101553567A/zh active Pending
- 2007-07-19 CA CA002659032A patent/CA2659032A1/en not_active Abandoned
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