JP2009543788A - ムコール症および他の真菌性疾患を処置するための組成物および方法 - Google Patents

ムコール症および他の真菌性疾患を処置するための組成物および方法 Download PDF

Info

Publication number
JP2009543788A
JP2009543788A JP2009519562A JP2009519562A JP2009543788A JP 2009543788 A JP2009543788 A JP 2009543788A JP 2009519562 A JP2009519562 A JP 2009519562A JP 2009519562 A JP2009519562 A JP 2009519562A JP 2009543788 A JP2009543788 A JP 2009543788A
Authority
JP
Japan
Prior art keywords
iron
mucormycosis
deferasirox
mycosis
antifungal agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2009519562A
Other languages
English (en)
Japanese (ja)
Other versions
JP2009543788A5 (enExample
Inventor
アシュラフ エス. イブラヒム,
ブラッド ジェイ. スペルバーグ,
ジョン イー. エドワーズ,
Original Assignee
ロサンゼルス バイオメディカル リサーチ インスティテュート アット ハーバー− ユーシーエルエー メディカル センター
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ロサンゼルス バイオメディカル リサーチ インスティテュート アット ハーバー− ユーシーエルエー メディカル センター filed Critical ロサンゼルス バイオメディカル リサーチ インスティテュート アット ハーバー− ユーシーエルエー メディカル センター
Publication of JP2009543788A publication Critical patent/JP2009543788A/ja
Publication of JP2009543788A5 publication Critical patent/JP2009543788A5/ja
Pending legal-status Critical Current

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41961,2,4-Triazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4412Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2009519562A 2006-07-13 2007-07-13 ムコール症および他の真菌性疾患を処置するための組成物および方法 Pending JP2009543788A (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US83109906P 2006-07-13 2006-07-13
US89762007P 2007-01-26 2007-01-26
US90407507P 2007-02-27 2007-02-27
PCT/US2007/016065 WO2008008537A2 (en) 2006-07-13 2007-07-13 Combi) compositions for the treatment of mucormycosis. comprising iron chelator and antifungal agent

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2012258262A Division JP2013040212A (ja) 2006-07-13 2012-11-27 ムコール症および他の真菌性疾患を処置するための組成物および方法

Publications (2)

Publication Number Publication Date
JP2009543788A true JP2009543788A (ja) 2009-12-10
JP2009543788A5 JP2009543788A5 (enExample) 2011-08-11

Family

ID=38610625

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2009519562A Pending JP2009543788A (ja) 2006-07-13 2007-07-13 ムコール症および他の真菌性疾患を処置するための組成物および方法
JP2012258262A Pending JP2013040212A (ja) 2006-07-13 2012-11-27 ムコール症および他の真菌性疾患を処置するための組成物および方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2012258262A Pending JP2013040212A (ja) 2006-07-13 2012-11-27 ムコール症および他の真菌性疾患を処置するための組成物および方法

Country Status (18)

Country Link
US (1) US20100129434A1 (enExample)
EP (2) EP2043636A2 (enExample)
JP (2) JP2009543788A (enExample)
KR (1) KR20090036587A (enExample)
AU (1) AU2007272781B2 (enExample)
BR (1) BRPI0714221A2 (enExample)
CA (1) CA2657634A1 (enExample)
CL (1) CL2007002026A1 (enExample)
IL (1) IL196389A0 (enExample)
MA (1) MA30625B1 (enExample)
MX (1) MX2009000506A (enExample)
NO (1) NO20090565L (enExample)
NZ (1) NZ574862A (enExample)
RU (1) RU2464024C2 (enExample)
SG (1) SG177122A1 (enExample)
TN (1) TN2009000004A1 (enExample)
TW (1) TWI448285B (enExample)
WO (1) WO2008008537A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2023057423A (ja) * 2021-10-11 2023-04-21 国立大学法人 熊本大学 ムコール症治療薬

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2755273A1 (en) * 2009-03-19 2010-09-23 Los Angeles Biomedical Research Institute At Harbor-Ucla Medical Center Vaccine compositions and methods for treatment of mucormycosis and other fungal diseases
US8980876B2 (en) 2010-10-28 2015-03-17 The Procter & Gamble Company Inhibition of microbial growth by aconitase inhibition
US20150246027A1 (en) * 2012-11-12 2015-09-03 Cipla Limited Fixed dose pharmaceutical composition comprising deferasirox and deferiprone
US11229685B2 (en) 2013-01-29 2022-01-25 Case Western Reserve University Fungal iron acquisition inhibitors and uses thereof
US20160199361A1 (en) * 2013-08-19 2016-07-14 Rutgers, The State University Of New Jersey Method of Inducing An Anti-Retroviral Immune Response By Counter-Acting Retro-Virus Induced Anti-Apoptosis
WO2016025611A2 (en) * 2014-08-13 2016-02-18 Zoneone Pharma, Inc. Pharmaceutical formulations of chelating agents as a metal removal treatment system
WO2016025559A1 (en) * 2014-08-13 2016-02-18 Zoneone Pharma, Inc. Pharmaceutical formulations of and methods to prepare chelating agents for efficient metal removal treatment systems
US11298364B2 (en) * 2015-08-31 2022-04-12 The University Of Adelaide Methods and products for preventing and/or treating microorganism infections comprising iron chelators and non-iron porphyrins
US10960002B2 (en) 2016-05-13 2021-03-30 The Brigham And Women's Hospital, Inc. Volatile metabolite profiles for the diagnosis and treatment of Mucorales fungi
FR3095755A1 (fr) * 2019-05-10 2020-11-13 Balmes Transplantation Nouveaux médicaments cytoprotecteurs
CN113905715B (zh) 2019-06-28 2025-04-15 宝洁公司 光增强处理方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004045609A2 (en) * 2002-11-19 2004-06-03 Relivia Srl Hydroxypyridinones for the local treatment of skin microcirculatory disorders
WO2005051411A1 (de) * 2003-11-28 2005-06-09 Biofrontera Discovery Gmbh Neues arzneimittel oxachelin und derivate

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8329043D0 (en) * 1983-10-31 1983-11-30 Hider R C Pharmaceutical compositions
US4698431A (en) * 1985-11-12 1987-10-06 The United States Of America As Represented By The United States Department Of Energy Hydroxypyridonate chelating agents
PH31594A (en) * 1993-09-30 1998-11-03 Janssen Pharmaceutica Nv Oral formulations on an antifungal.
TW533205B (en) * 1996-06-25 2003-05-21 Novartis Ag Substituted 3,5-diphenyl-l,2,4-triazoles and their pharmaceutical composition
WO1999009997A1 (en) * 1997-08-26 1999-03-04 Board Of Regents, The University Of Texas System Edta and other chelators with or without antifungal antimicrobial agents for the prevention and treatment of fungal infections
DE50111949D1 (de) * 2000-12-16 2007-03-15 Alstom Technology Ltd Komponente einer Strömungsmaschine
GB0223978D0 (en) 2002-10-15 2002-11-20 Novartis Ag Organic compound
AU2003302274A1 (en) * 2002-12-31 2004-07-29 Novartis Ag Aerosolizable pharmaceutical formulation for fungal infection therapy
WO2004108114A2 (en) * 2003-03-31 2004-12-16 Dinesh Shantilal Patel Anti-fungal composition and a process for its manufacture

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004045609A2 (en) * 2002-11-19 2004-06-03 Relivia Srl Hydroxypyridinones for the local treatment of skin microcirculatory disorders
WO2005051411A1 (de) * 2003-11-28 2005-06-09 Biofrontera Discovery Gmbh Neues arzneimittel oxachelin und derivate

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
JPN6012044956; BOELAERT,J.R. et al: Kidney International Vol.45, No.3, 1994, p.667-71 *
JPN6012044957; MENCACCI,A. et al: Journal of Infectious Diseases Vol.175, No.6, 1997, p.1467-1476 *
JPN6012044958; IBRAHIM,A.S. et al: 'Iron Chelation as a Novel Therapy for Experimental Mucormycosis' Abstracts of the Interscience Conference on Antimicrobial Agents and Chemotherapy Vol.45, 2005, p.39 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2023057423A (ja) * 2021-10-11 2023-04-21 国立大学法人 熊本大学 ムコール症治療薬

Also Published As

Publication number Publication date
AU2007272781A1 (en) 2008-01-17
TW200816994A (en) 2008-04-16
MX2009000506A (es) 2009-05-20
BRPI0714221A2 (pt) 2013-01-01
WO2008008537A2 (en) 2008-01-17
MA30625B1 (fr) 2009-08-03
KR20090036587A (ko) 2009-04-14
EP2043636A2 (en) 2009-04-08
CA2657634A1 (en) 2008-01-17
TWI448285B (zh) 2014-08-11
IL196389A0 (en) 2009-09-22
AU2007272781B2 (en) 2012-10-18
RU2464024C2 (ru) 2012-10-20
NO20090565L (no) 2009-03-30
JP2013040212A (ja) 2013-02-28
EP2412371A1 (en) 2012-02-01
US20100129434A1 (en) 2010-05-27
SG177122A1 (en) 2012-01-30
WO2008008537A3 (en) 2008-04-24
CL2007002026A1 (es) 2008-06-06
TN2009000004A1 (en) 2010-08-19
NZ574862A (en) 2012-02-24
RU2009104961A (ru) 2010-08-20

Similar Documents

Publication Publication Date Title
AU2007272781B2 (en) Combi) compositions for the treatment of mucormycosis. comprising iron chelator and antifungal agent
Hoenigl et al. The antifungal pipeline: fosmanogepix, ibrexafungerp, olorofim, opelconazole, and rezafungin
Perfect Treatment of non-Aspergillus moulds in immunocompromised patients, with amphotericin B lipid complex
Ibrahim et al. The iron chelator deferasirox protects mice from mucormycosis through iron starvation
Maertens et al. Mucormycosis in allogeneic bone marrow transplant recipients: report of five cases and review of the role of iron overload in the pathogenesis
RU2262952C2 (ru) ЛЕЧЕНИЕ ГРИБКОВОЙ ИНФЕКЦИИ ПРОТИВОГРИБКОВЫМИ ПРЕПАРАТАМИ ИЗ ГРУППЫ ПОЛИЕНОВ ИЛИ ИНГИБИТОРОВ β-ГЛЮКАНСИНТАЗЫ В КОМБИНАЦИИ С АНТИ-hsp90-АНТИТЕЛАМИ
Almajid et al. Fosmanogepix: the novel anti-fungal agent’s comprehensive review of in vitro, in vivo, and current insights from advancing clinical trials
Peterson Oral candidiasis
Spencer et al. Systemic fungal infections: A pharmacist/researcher perspective
Bormann et al. Review of the pharmacology and clinical studies of micafungin
US9901615B2 (en) Method for treatment of gastric ulcers
Saoulidis et al. Antifungal activity of posaconazole and granulocyte colony‐stimulating factor in the treatment of disseminated zygomycosis (mucormycosis) in a neutropaenic murine model
Marin et al. Trichosporon beigelii pneumonia in a neutropenic patient
TWI712410B (zh) 艾曲波帕用於製備抗隱球菌藥物之用途
CN101511360A (zh) 用于毛霉病和其它真菌疾病治疗的组合物及方法
Flattery et al. New model of oropharyngeal and gastrointestinal colonization by Candida albicans in CD4+ T-cell-deficient mice for evaluation of antifungal agents
De Pauw Treatment of documented and suspected neutropenia-associated invasive fungal infections
Sahu et al. Mucormycosis in Indian COVID-19 patients: Insight into its patho-genesis, clinical manifestation, and management strategies. Antibiotics (Basel) 2021; 10: 1079
Khan et al. Efficacy of liposomal amphotericin B in treating fungal meningitis in AIDS Patients: A review article
Bhutadal et al. Successful treatment of peritonitis by C. bertholletiae in chronic kidney failure patient on continuous
Hebart et al. Management of invasive fungal infections in oncological patients
CN116712442A (zh) 化合物hex和/或化合物pom-hex在预防和/或治疗真菌感染的药物中的应用
Ghannoum et al. In vitro evaluation of voriconazole in combination with antifungals
HK1261465A1 (en) Dosing regimens for treatment of fungal infections
EP2680857A1 (en) Oleyl phosphocholine for the treatment of mycosis

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20100630

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20100630

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20110615

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20120827

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20121127

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20121221