JP2009543783A5 - - Google Patents

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Publication number
JP2009543783A5
JP2009543783A5 JP2009519541A JP2009519541A JP2009543783A5 JP 2009543783 A5 JP2009543783 A5 JP 2009543783A5 JP 2009519541 A JP2009519541 A JP 2009519541A JP 2009519541 A JP2009519541 A JP 2009519541A JP 2009543783 A5 JP2009543783 A5 JP 2009543783A5
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JP
Japan
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substituted
alkynyl
alkoxy
alkenyl
cycloalkyl
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JP2009519541A
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English (en)
Japanese (ja)
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JP2009543783A (ja
JP6125741B2 (ja
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Priority claimed from PCT/US2007/015966 external-priority patent/WO2008008476A2/en
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Publication of JP2009543783A5 publication Critical patent/JP2009543783A5/ja
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JP2009519541A 2006-07-12 2007-07-11 可逆的なホスホトリエステル電荷中和保護基による核酸の形質導入可能な送達 Active JP6125741B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US83057206P 2006-07-12 2006-07-12
US60/830,572 2006-07-12
PCT/US2007/015966 WO2008008476A2 (en) 2006-07-12 2007-07-11 Transducible delivery of nucleic acids by reversible phosphotriester charge neutralization protecting groups

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2014217097A Division JP2015062421A (ja) 2006-07-12 2014-10-24 可逆的なホスホトリエステル電荷中和保護基による核酸の形質導入可能な送達

Publications (3)

Publication Number Publication Date
JP2009543783A JP2009543783A (ja) 2009-12-10
JP2009543783A5 true JP2009543783A5 (enExample) 2010-07-08
JP6125741B2 JP6125741B2 (ja) 2017-05-17

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ID=38923923

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2009519541A Active JP6125741B2 (ja) 2006-07-12 2007-07-11 可逆的なホスホトリエステル電荷中和保護基による核酸の形質導入可能な送達
JP2014217097A Pending JP2015062421A (ja) 2006-07-12 2014-10-24 可逆的なホスホトリエステル電荷中和保護基による核酸の形質導入可能な送達

Family Applications After (1)

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JP2014217097A Pending JP2015062421A (ja) 2006-07-12 2014-10-24 可逆的なホスホトリエステル電荷中和保護基による核酸の形質導入可能な送達

Country Status (7)

Country Link
US (1) US20090093425A1 (enExample)
EP (1) EP2046964B1 (enExample)
JP (2) JP6125741B2 (enExample)
CN (1) CN101506368B (enExample)
AU (1) AU2007272906B2 (enExample)
CA (1) CA2659103C (enExample)
WO (1) WO2008008476A2 (enExample)

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DK2872485T3 (da) 2012-07-13 2021-03-08 Wave Life Sciences Ltd Asymmetrisk hjælpegruppe
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AU2013315524B2 (en) 2012-09-12 2019-01-31 Quark Pharmaceuticals, Inc. Double-stranded oligonucleotide molecules to p53 and methods of use thereof
DK2895607T3 (da) 2012-09-12 2021-05-25 Quark Pharmaceuticals Inc Dobbeltstrengede oligonukleotidmolekyler til ddit4 og fremgangsmåder til anvendelse deraf
JP2016507484A (ja) * 2012-12-06 2016-03-10 メルク・シャープ・アンド・ドーム・コーポレーションＭｅｒｃｋ Ｓｈａｒｐ ＆ Ｄｏｈｍｅ Ｃｏｒｐ． ジスルフィドマスキングプロドラッグ組成物および方法
CA2892676A1 (en) * 2012-12-06 2014-06-12 Merck Sharp & Dohme Corp. Nucleoside kinase bypass compositions and methods
CA2907184C (en) 2013-03-15 2022-12-06 Sutter West Bay Hospitals Falz for use as a target for therapies to treat cancer
EP3027223A1 (en) 2013-07-31 2016-06-08 QBI Enterprises Ltd. Methods of use of sphingolipid polyalkylamine oligonucleotide compounds
US9889200B2 (en) 2013-07-31 2018-02-13 Qbi Enterprises Ltd. Sphingolipid-polyalkylamine-oligonucleotide compounds
CN111437395A (zh) * 2013-08-29 2020-07-24 希望之城 细胞穿透缀合物及其使用方法
WO2015108048A1 (ja) 2014-01-15 2015-07-23 株式会社新日本科学 抗腫瘍作用を有するキラル核酸アジュバンド及び抗腫瘍剤
US10322173B2 (en) 2014-01-15 2019-06-18 Shin Nippon Biomedical Laboratories, Ltd. Chiral nucleic acid adjuvant having anti-allergic activity, and anti-allergic agent
EP3095461A4 (en) 2014-01-15 2017-08-23 Shin Nippon Biomedical Laboratories, Ltd. Chiral nucleic acid adjuvant having immunity induction activity, and immunity induction activator
KR102423317B1 (ko) 2014-01-16 2022-07-22 웨이브 라이프 사이언시스 리미티드 키랄 디자인
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WO2018035380A1 (en) 2016-08-17 2018-02-22 Solstice Biologics, Ltd. Polynucleotide constructs
WO2019006455A1 (en) 2017-06-30 2019-01-03 Solstice Biologics, Ltd. AUXILIARIES OF CHIRAL PHOSPHORAMIDITIS AND METHODS OF USE THEREOF
JP7282379B2 (ja) * 2017-08-22 2023-05-29 国立大学法人東海国立大学機構 修飾ポリヌクレオチド
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