JP2009541220A - 糖尿病性高血糖および糖尿病合併症の制御のための抗糖尿病薬としてのメトホルミンｒ−（＋）リポエート - Google Patents
糖尿病性高血糖および糖尿病合併症の制御のための抗糖尿病薬としてのメトホルミンｒ−（＋）リポエート Download PDFInfo
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- JP2009541220A JP2009541220A JP2009515506A JP2009515506A JP2009541220A JP 2009541220 A JP2009541220 A JP 2009541220A JP 2009515506 A JP2009515506 A JP 2009515506A JP 2009515506 A JP2009515506 A JP 2009515506A JP 2009541220 A JP2009541220 A JP 2009541220A
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- Prior art keywords
- metformin
- lipoate
- diabetic
- pharmaceutically acceptable
- lipoic acid
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| PCT/US2007/014034 WO2007149313A1 (en) | 2006-06-16 | 2007-06-14 | Metformin r-(+) lipoate as an antidiabetic agent for control of diabetic hyperglycemia and diabetic complications |
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| JP2021503449A (ja) * | 2017-11-17 | 2021-02-12 | セリックス バイオ プライヴェート リミテッドＣｅｌｌｉｘ Ｂｉｏ Ｐｒｉｖａｔｅ Ｌｉｍｉｔｅｄ | 眼障害の処置のための組成物及び方法 |
| JP7005071B1 (ja) | 2021-03-30 | 2022-01-21 | ▲広▼州大学 | メトホルミン塩の調製方法 |
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| WO2009111635A2 (en) | 2008-03-05 | 2009-09-11 | Encore Health, Llc | Dithiol compounds, derivatives, and uses therefor |
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| US20100099751A1 (en) * | 2008-10-21 | 2010-04-22 | Al-Mulla Fahd | Method of treating diabetes-related vascular complications |
| WO2010047717A1 (en) * | 2008-10-24 | 2010-04-29 | Biolink Life Sciences, Inc. | Stable, water-insoluble r-(+)-alpha-lipoic acid salt useful for the treatment of diabetes mellitus and its co-morbidities |
| EP2442645B1 (en) | 2009-06-15 | 2014-08-27 | Encore Health, Llc | Choline esters |
| DK2442647T3 (en) | 2009-06-15 | 2016-05-30 | Encore Health Llc | Dithiolforbindelser, derivatives thereof, and the uses of these |
| WO2011130719A2 (en) | 2010-04-15 | 2011-10-20 | The Regents Of The University Of Michigan | A biosynthetic pathway for heterologous expression of a nonribosomal peptide synthetase drug and analogs |
| IT1399923B1 (it) * | 2010-05-11 | 2013-05-09 | Cbb Net S A | Procedimento di preparazione di sali dell'acido (r) alfa-lipoico loro formulazione ed uso nelle composizioni farmaceutiche in forma di compresse che li contengono |
| US20120178813A1 (en) | 2011-01-12 | 2012-07-12 | Thetis Pharmaceuticals Llc | Lipid-lowering antidiabetic agent |
| US8440723B2 (en) * | 2011-05-11 | 2013-05-14 | Banavara L. Mylari | Metformin salts of salicylic acid and its congeners |
| US8765811B2 (en) | 2012-07-10 | 2014-07-01 | Thetis Pharmaceuticals Llc | Tri-salt form of metformin |
| US9382187B2 (en) | 2012-07-10 | 2016-07-05 | Thetis Pharmaceuticals Llc | Tri-salt form of metformin |
| WO2014124141A1 (en) * | 2013-02-07 | 2014-08-14 | Mylari Banavara L | Metformin derivatives for treating diabetes |
| WO2015022613A1 (en) * | 2013-08-11 | 2015-02-19 | Mahesh Kandula | Compositions and methods for the treatment of diabetes and pre-diabetes |
| US20150073057A1 (en) * | 2013-09-06 | 2015-03-12 | Biokier, Inc. | Composition and method for treatment of diabetes |
| CN106455563A (zh) | 2014-03-03 | 2017-02-22 | 安可视觉公司 | 硫辛酸胆碱酯组合物及使用方法 |
| EP3140316A1 (en) | 2014-05-05 | 2017-03-15 | Thetis Pharmaceuticals LLC | Compositions and methods relating to ionic salts of peptides |
| EP3157936B1 (en) | 2014-06-18 | 2018-10-17 | Thetis Pharmaceuticals LLC | Mineral amino-acid complexes of active agents |
| US9242008B2 (en) | 2014-06-18 | 2016-01-26 | Thetis Pharmaceuticals Llc | Mineral amino-acid complexes of fatty acids |
| JP6906047B2 (ja) | 2016-06-03 | 2021-07-21 | テティス・ファーマシューティカルズ・エルエルシー | 特異的炎症収束性メディエーターの塩に関連する組成物及び方法 |
| KR102405239B1 (ko) * | 2017-11-17 | 2022-06-08 | 셀릭스 바이오 프라이빗 리미티드 | 눈 질환 및 피부 질환의 치료를 위한 화합물, 조성물 및 방법 |
| CN110037998A (zh) * | 2018-01-16 | 2019-07-23 | 镇学初 | 二甲双胍盐在治疗脑梗死中的用途 |
| CN110294738A (zh) * | 2019-07-22 | 2019-10-01 | 通化师范学院 | 硫辛酸衍生物及其制备方法和用途 |
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| US6197340B1 (en) * | 1998-05-28 | 2001-03-06 | Medical Research Institute | Controlled release lipoic acid |
| US20050085498A1 (en) * | 1998-05-28 | 2005-04-21 | Byrd Edward A. | Oral formulation of lipid soluble thiamine, lipoic acid, creatine derivative, and L-arginine alpha-ketoglutarate |
| FR2796551B1 (fr) * | 1999-07-23 | 2003-07-25 | Lipha | Nouveaux sels de metformine, leur procede d'obtention et les compositions pharmaceutiques en renfermant |
| US6693094B2 (en) * | 2001-03-22 | 2004-02-17 | Chrono Rx Llc | Biguanide and sulfonylurea formulations for the prevention and treatment of insulin resistance and type 2 diabetes mellitus |
| US20030220301A1 (en) * | 2002-02-14 | 2003-11-27 | Sonus Pharmaceuticals, Inc. | Metformin salts of lipophilic acids |
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2007
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- 2007-06-14 CA CA002691775A patent/CA2691775A1/en not_active Abandoned
- 2007-06-14 EP EP07796141A patent/EP2046773A1/en not_active Withdrawn
- 2007-06-14 WO PCT/US2007/014034 patent/WO2007149313A1/en not_active Ceased
- 2007-06-14 JP JP2009515506A patent/JP2009541220A/ja not_active Withdrawn
- 2007-06-14 CN CNA2007800302762A patent/CN101522658A/zh active Pending
- 2007-06-15 CL CL200701759A patent/CL2007001759A1/es unknown
- 2007-06-15 AR ARP070102661A patent/AR061500A1/es unknown
- 2007-06-15 TW TW096121712A patent/TW200816986A/zh unknown
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2008
- 2008-12-15 IL IL195959A patent/IL195959A0/en unknown
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2021503449A (ja) * | 2017-11-17 | 2021-02-12 | セリックス バイオ プライヴェート リミテッドＣｅｌｌｉｘ Ｂｉｏ Ｐｒｉｖａｔｅ Ｌｉｍｉｔｅｄ | 眼障害の処置のための組成物及び方法 |
| JP7006990B2 (ja) | 2017-11-17 | 2022-02-10 | セリックス バイオ プライヴェート リミテッド | 眼障害の処置のための組成物及び方法 |
| JP7005071B1 (ja) | 2021-03-30 | 2022-01-21 | ▲広▼州大学 | メトホルミン塩の調製方法 |
| JP2022155436A (ja) * | 2021-03-30 | 2022-10-13 | ▲広▼州大学 | メトホルミン塩の調製方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| CL2007001759A1 (es) | 2008-10-24 |
| TW200816986A (en) | 2008-04-16 |
| CN101522658A (zh) | 2009-09-02 |
| EP2046773A1 (en) | 2009-04-15 |
| IL195959A0 (en) | 2009-09-22 |
| US7973073B2 (en) | 2011-07-05 |
| WO2007149313A1 (en) | 2007-12-27 |
| CA2691775A1 (en) | 2007-12-27 |
| US20070293562A1 (en) | 2007-12-20 |
| AR061500A1 (es) | 2008-09-03 |
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