JP2009538852A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2009538852A5 JP2009538852A5 JP2009512481A JP2009512481A JP2009538852A5 JP 2009538852 A5 JP2009538852 A5 JP 2009538852A5 JP 2009512481 A JP2009512481 A JP 2009512481A JP 2009512481 A JP2009512481 A JP 2009512481A JP 2009538852 A5 JP2009538852 A5 JP 2009538852A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- methyl
- pyrido
- imidazo
- pyrazine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 0 *c(nc1I)c2[n]1c1nc(*)ccc1nc2* Chemical compound *c(nc1I)c2[n]1c1nc(*)ccc1nc2* 0.000 description 4
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US80925106P | 2006-05-30 | 2006-05-30 | |
| PCT/EP2007/004747 WO2007137819A1 (en) | 2006-05-30 | 2007-05-29 | 4-AMINO-PYRIDO[3,2-e]PYRAZINES, THEIR USE AS INHIBITORS OF PHOSPHODIESTERASE 10, AND PROCESSES FOR PREPARING THEM |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009538852A JP2009538852A (ja) | 2009-11-12 |
| JP2009538852A5 true JP2009538852A5 (https=) | 2010-07-15 |
Family
ID=38441601
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009512481A Pending JP2009538852A (ja) | 2006-05-30 | 2007-05-29 | ４−アミノ−ピリド［３，２−ｅ］ピラジン、該化合物のホスホジエステラーゼ１０の阻害剤としての使用、及び該化合物の製造方法 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20070299079A1 (https=) |
| EP (1) | EP2021341A1 (https=) |
| JP (1) | JP2009538852A (https=) |
| CN (1) | CN101448829A (https=) |
| AR (1) | AR060984A1 (https=) |
| AU (1) | AU2007267391A1 (https=) |
| BR (1) | BRPI0711857A2 (https=) |
| CA (1) | CA2653412A1 (https=) |
| CL (1) | CL2007001555A1 (https=) |
| MX (1) | MX2008015308A (https=) |
| PE (1) | PE20080266A1 (https=) |
| TW (1) | TW200815436A (https=) |
| WO (1) | WO2007137819A1 (https=) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2671980C (en) * | 2006-12-13 | 2015-05-05 | Aska Pharmaceutical Co., Ltd. | Quinoxaline derivatives |
| US20090143392A1 (en) * | 2007-11-30 | 2009-06-04 | Elbion Gmbh | Methods of Treating Obesity and Metabolic Disorders |
| US20090143361A1 (en) * | 2007-11-30 | 2009-06-04 | Elbion Gmbh | Pyrido[3,2-E]Pyrazines, Process For Preparing The Same, And Their Use As Inhibitors Of Phosphodiesterase 10 |
| KR20100110804A (ko) * | 2007-11-30 | 2010-10-13 | 와이어쓰 엘엘씨 | 포스포디에스테라제 10의 저해물질로서의 아릴 및 헤테로아릴 융합된 이미다조[1,5-ａ]피라진 |
| WO2010054260A1 (en) * | 2008-11-07 | 2010-05-14 | Biotie Therapies Gmbh | Imidazo[5,1-c][1,2,4]benzotriazine derivatives as inhibitors of phosphodiesterases |
| NZ603789A (en) | 2010-05-26 | 2015-03-27 | Sunovion Pharmaceuticals Inc | Heteroaryl compounds and methods of use thereof |
| DE102010042833B4 (de) | 2010-10-22 | 2018-11-08 | Helmholtz-Zentrum Dresden - Rossendorf E.V. | Neue Halogenalkoxychinazoline, deren Herstellung und Verwendung |
| US9540379B2 (en) | 2011-01-31 | 2017-01-10 | Boehringer Ingelheim International Gmbh | (1,2,4)triazolo[4,3-A]quinoxaline derivatives as inhibitors of phosphodiesterases |
| CN103476757A (zh) | 2011-02-18 | 2013-12-25 | 阿勒根公司 | 作为磷酸二酯酶10(pde10a)的抑制剂的取代的6,7-二烷氧基-3-异喹啉醇衍生物 |
| US9938269B2 (en) | 2011-06-30 | 2018-04-10 | Abbvie Inc. | Inhibitor compounds of phosphodiesterase type 10A |
| JP2014526453A (ja) * | 2011-09-09 | 2014-10-06 | ハー・ルンドベック・アクチエゼルスカベット | ピリジン化合物およびそれらの使用 |
| SG11201502728WA (en) | 2011-10-10 | 2015-05-28 | Lundbeck & Co As H | Pde9i with imidazo pyrazinone backbone |
| AU2012334011A1 (en) | 2011-11-09 | 2014-05-15 | AbbVie Deutschland GmbH & Co. KG | Heterocyclic carboxamides useful as inhibitors of phosphodiesterase type 10A |
| US20130116241A1 (en) | 2011-11-09 | 2013-05-09 | Abbvie Inc. | Novel inhibitor compounds of phosphodiesterase type 10a |
| BR112014018199A8 (pt) | 2012-01-26 | 2021-03-02 | H Lundbeck As | inibidores da pde9 com cadeia principal imidazo triazinona, composição farmacêutica que os compreende, uso dos referidos inibidores e processo para sua preparação |
| MX361539B (es) | 2012-04-25 | 2018-12-10 | Takeda Pharmaceuticals Co | Compuesto heterociclico nitrogenado. |
| RU2644558C2 (ru) | 2012-06-19 | 2018-02-13 | Сановьон Фармасьютикалз Инк. | Гетероарильные соединения и способы их применения |
| EP2873669A4 (en) | 2012-07-13 | 2015-11-25 | Takeda Pharmaceutical | HETEROCYCLIC CONNECTION |
| US20140045856A1 (en) * | 2012-07-31 | 2014-02-13 | Boehringer Ingelheim International Gmbh | 4-Methyl-2,3,5,9,9b-pentaaza-cyclopenta[a]naphthalenes |
| UY34980A (es) | 2012-08-17 | 2014-03-31 | Abbvie Inc | Nuevos compuestos inhibidores de la fosfodiesterasa del tipo 10a |
| EP2895489B1 (en) | 2012-09-17 | 2017-10-18 | AbbVie Deutschland GmbH & Co. KG | Novel inhibitor compounds of phosphodiesterase type 10a |
| WO2014071044A1 (en) | 2012-11-01 | 2014-05-08 | Allergan, Inc. | Substituted 6,7-dialkoxy-3-isoquinoline derivatives as inhibitors of phosphodiesterase 10 (pde10a) |
| US9790203B2 (en) | 2012-11-26 | 2017-10-17 | Abbvie Inc. | Inhibitor compounds of phosphodiesterase type 10A |
| US9200005B2 (en) | 2013-03-13 | 2015-12-01 | AbbVie Deutschland GmbH & Co. KG | Inhibitor compounds of phosphodiesterase type 10A |
| CN105209462A (zh) | 2013-03-14 | 2015-12-30 | 艾伯维德国有限责任两合公司 | 磷酸二酯酶10a型的新型抑制剂化合物 |
| EP2975031A4 (en) | 2013-03-14 | 2017-04-19 | Takeda Pharmaceutical Company Limited | Heterocyclic compound |
| JP6427491B2 (ja) | 2013-07-03 | 2018-11-21 | 武田薬品工業株式会社 | 複素環化合物 |
| ES2950424T3 (es) | 2013-07-03 | 2023-10-09 | Takeda Pharmaceuticals Co | Compuesto de amida |
| US9200016B2 (en) | 2013-12-05 | 2015-12-01 | Allergan, Inc. | Substituted 6, 7-dialkoxy-3-isoquinoline derivatives as inhibitors of phosphodiesterase 10 (PDE 10A) |
| CN103980281B (zh) * | 2014-05-27 | 2016-06-08 | 天津市斯芬克司药物研发有限公司 | 一种咪唑吡嗪化合物及其制备方法 |
| HRP20240082T1 (hr) | 2015-07-07 | 2024-03-29 | H. Lundbeck A/S | Inhibitor pde9 s okosnicom imidazopirazinona za liječenje perifernih bolesti |
| FI3801526T3 (fi) | 2018-05-25 | 2024-03-20 | Cardurion Pharmaceuticals Inc | 6-[(3s,4s)-4-metyyli-1-(pyrimidin-2-yylimetyyli)pyrrolidin-3-yyli]-3-tetrahydropyran-4-yyli-7h-imidatso[1,5-a]pyratsin-8-onin monohydraattimuotoja ja kiteisiä muotoja |
| EP3843737A4 (en) | 2018-08-31 | 2022-06-01 | Imara Inc. | PDE9 INHIBITORS FOR THE TREATMENT OF SICKLE CELL DISEASE |
| WO2020065583A1 (en) | 2018-09-28 | 2020-04-02 | Takeda Pharmaceutical Company Limited | Balipodect for treating or preventing autism spectrum disorders |
| CN114524808B (zh) * | 2022-02-21 | 2023-10-24 | 深圳市儿童医院 | 一种吡唑衍生物及其作为pde10抑制剂的用途 |
| CN114524806B (zh) * | 2022-02-22 | 2024-09-03 | 深圳市儿童医院 | 一种三氮唑衍生物及其作为pde10抑制剂的用途 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE430149T1 (de) * | 1998-03-04 | 2009-05-15 | Bristol Myers Squibb Co | Heterocyclen substituierte imidazopyrazine als protein- tyrosin-kinase-inhibitoren |
| JPH11292878A (ja) * | 1998-04-09 | 1999-10-26 | Yamanouchi Pharmaceut Co Ltd | イミダゾナフチリジン誘導体 |
| US20030032579A1 (en) * | 2001-04-20 | 2003-02-13 | Pfizer Inc. | Therapeutic use of selective PDE10 inhibitors |
| IL149106A0 (en) * | 2001-04-20 | 2002-11-10 | Pfizer Prod Inc | Therapeutic use of selective pde10 inhibitors |
| TW200817400A (en) * | 2006-05-30 | 2008-04-16 | Elbion Ag | Pyrido [3,2-e] pyrazines, their use as inhibitors of phosphodiesterase 10, and processes for preparing them |
-
2007
- 2007-05-18 TW TW096117904A patent/TW200815436A/zh unknown
- 2007-05-24 US US11/753,260 patent/US20070299079A1/en not_active Abandoned
- 2007-05-29 BR BRPI0711857-0A patent/BRPI0711857A2/pt not_active IP Right Cessation
- 2007-05-29 JP JP2009512481A patent/JP2009538852A/ja active Pending
- 2007-05-29 AU AU2007267391A patent/AU2007267391A1/en not_active Abandoned
- 2007-05-29 CA CA002653412A patent/CA2653412A1/en not_active Abandoned
- 2007-05-29 EP EP07725638A patent/EP2021341A1/en not_active Withdrawn
- 2007-05-29 CN CNA2007800178341A patent/CN101448829A/zh active Pending
- 2007-05-29 WO PCT/EP2007/004747 patent/WO2007137819A1/en not_active Ceased
- 2007-05-29 MX MX2008015308A patent/MX2008015308A/es not_active Application Discontinuation
- 2007-05-29 AR ARP070102308A patent/AR060984A1/es unknown
- 2007-05-30 CL CL2007001555A patent/CL2007001555A1/es unknown
- 2007-05-30 PE PE2007000675A patent/PE20080266A1/es not_active Application Discontinuation
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2009538852A5 (https=) | ||
| EP3317289B1 (en) | Novel substituted aminothiazolopyrimidinedione for the treatment and prophylaxis of virus infection | |
| JP6236173B2 (ja) | 脊髄性筋萎縮症を処置するための化合物 | |
| AU2016256728B2 (en) | Thiadiazole analogs thereof and methods for treating smn-deficiency-related-conditions | |
| JP5820921B2 (ja) | １，２−二置換複素環式化合物 | |
| CA2866143C (en) | Pyrazolo[1,5-a]pyrimidine-based compounds, compositions comprising them, and methods of their use | |
| JP6600319B2 (ja) | ヒストンデアセチラーゼ阻害薬及び組成物並びにそれらの使用の方法 | |
| CN115448910A (zh) | 一种哒嗪类衍生物抑制剂、其制备方法和应用 | |
| US20090239874A1 (en) | Pyrido[3,2-e]pyrazines, their use as inhibitors of phospohodiesterase 10, and processes for preparing them | |
| JP2009538853A5 (https=) | ||
| US20070299079A1 (en) | 4-AMINO-PYRIDO[3,2-e]PYRAZINES, THEIR USE AS INHIBITORS OF PHOSPHODIESTERASE 10, AND PROCESSES FOR PREPARING THEM | |
| CN106008479B (zh) | 作为磷脂酰肌醇3-激酶δ抑制剂的取代嘧啶类化合物及其应用 | |
| CN102164604A (zh) | 用作激酶调节剂的稠合杂环化合物 | |
| AU2013355054B2 (en) | Diazole lactams | |
| CN108137539B (zh) | 取代的苯并咪唑、它们的制备和它们作为药物的用途 | |
| JP2020532585A (ja) | インターフェロン遺伝子刺激因子調節薬としての環状ジヌクレオチド | |
| CN105936635B (zh) | 作为磷脂酰肌醇3-激酶δ抑制剂的化合物及其应用 | |
| RS63581B1 (sr) | Inhibitori p38 kinaze smanjuju ekspresiju dux4 i nizvodnih gena u cilju lečenja fshd | |
| CN102388055A (zh) | 咪唑并[2,1-b][1,3,4]噻二唑衍生物 | |
| AU2011258005A1 (en) | Heterocyclic compounds as Janus kinase inhibitors | |
| RS52838B (sr) | Fenoksimetil heterociklična jedinjenja | |
| CN106414459B (zh) | 作为pde1抑制剂的六氢呋喃并吡咯 | |
| JP2021506852A (ja) | Ｈｂｖ感染と関連する疾患を治療するためのイソキサゾール化合物 | |
| CN112592345B (zh) | 一种三氮唑并吡嗪类化合物及其用途 | |
| TW201215607A (en) | Aryl-and heteroarylamid derivatives as PDE10A enzyme inhibitor |