JP2009534109A5 - - Google Patents
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- Publication number
- JP2009534109A5 JP2009534109A5 JP2009506630A JP2009506630A JP2009534109A5 JP 2009534109 A5 JP2009534109 A5 JP 2009534109A5 JP 2009506630 A JP2009506630 A JP 2009506630A JP 2009506630 A JP2009506630 A JP 2009506630A JP 2009534109 A5 JP2009534109 A5 JP 2009534109A5
- Authority
- JP
- Japan
- Prior art keywords
- stent
- coating
- region
- therapeutic agent
- coating composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000011248 coating agent Substances 0.000 claims 45
- 238000000576 coating method Methods 0.000 claims 45
- 239000008199 coating composition Substances 0.000 claims 27
- 239000003814 drug Substances 0.000 claims 21
- 229940124597 therapeutic agent Drugs 0.000 claims 21
- 239000002318 adhesion promoter Substances 0.000 claims 20
- 239000003795 chemical substances by application Substances 0.000 claims 8
- 208000037803 restenosis Diseases 0.000 claims 6
- 210000004204 blood vessel Anatomy 0.000 claims 5
- PPBRXRYQALVLMV-UHFFFAOYSA-N Styrene Natural products C=CC1=CC=CC=C1 PPBRXRYQALVLMV-UHFFFAOYSA-N 0.000 claims 4
- AWQFNUMHFNEWGS-UHFFFAOYSA-N 2-methylprop-1-ene;styrene Chemical group CC(C)=C.C=CC1=CC=CC=C1 AWQFNUMHFNEWGS-UHFFFAOYSA-N 0.000 claims 3
- VGGSQFUCUMXWEO-UHFFFAOYSA-N Ethene Chemical compound C=C VGGSQFUCUMXWEO-UHFFFAOYSA-N 0.000 claims 3
- 239000005977 Ethylene Substances 0.000 claims 3
- 229920001577 copolymer Polymers 0.000 claims 3
- HTXDPTMKBJXEOW-UHFFFAOYSA-N dioxoiridium Chemical compound O=[Ir]=O HTXDPTMKBJXEOW-UHFFFAOYSA-N 0.000 claims 3
- 229910000457 iridium oxide Inorganic materials 0.000 claims 3
- 239000000203 mixture Substances 0.000 claims 3
- HKVAMNSJSFKALM-GKUWKFKPSA-N Everolimus Chemical compound C1C[C@@H](OCCO)[C@H](OC)C[C@@H]1C[C@@H](C)[C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@](O)(O2)[C@H](C)CC[C@H]2C[C@H](OC)/C(C)=C/C=C/C=C/[C@@H](C)C[C@@H](C)C(=O)[C@H](OC)[C@H](O)/C(C)=C/[C@@H](C)C(=O)C1 HKVAMNSJSFKALM-GKUWKFKPSA-N 0.000 claims 2
- 229930012538 Paclitaxel Natural products 0.000 claims 2
- QJJXYPPXXYFBGM-LFZNUXCKSA-N Tacrolimus Chemical compound C1C[C@@H](O)[C@H](OC)C[C@@H]1\C=C(/C)[C@@H]1[C@H](C)[C@@H](O)CC(=O)[C@H](CC=C)/C=C(C)/C[C@H](C)C[C@H](OC)[C@H]([C@H](C[C@H]2C)OC)O[C@@]2(O)C(=O)C(=O)N2CCCC[C@H]2C(=O)O1 QJJXYPPXXYFBGM-LFZNUXCKSA-N 0.000 claims 2
- 239000000853 adhesive Substances 0.000 claims 2
- 230000001070 adhesive effect Effects 0.000 claims 2
- 239000003242 anti bacterial agent Substances 0.000 claims 2
- 230000002769 anti-restenotic effect Effects 0.000 claims 2
- 230000003115 biocidal effect Effects 0.000 claims 2
- 230000004663 cell proliferation Effects 0.000 claims 2
- 230000008602 contraction Effects 0.000 claims 2
- 229960005167 everolimus Drugs 0.000 claims 2
- 208000013403 hyperactivity Diseases 0.000 claims 2
- 230000005012 migration Effects 0.000 claims 2
- 238000013508 migration Methods 0.000 claims 2
- 229960001592 paclitaxel Drugs 0.000 claims 2
- KASDHRXLYQOAKZ-ZPSXYTITSA-N pimecrolimus Chemical compound C/C([C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@]2(O)O[C@@H]([C@H](C[C@H]2C)OC)[C@@H](OC)C[C@@H](C)C/C(C)=C/[C@H](C(C[C@H](O)[C@H]1C)=O)CC)=C\[C@@H]1CC[C@@H](Cl)[C@H](OC)C1 KASDHRXLYQOAKZ-ZPSXYTITSA-N 0.000 claims 2
- 229960005330 pimecrolimus Drugs 0.000 claims 2
- ZAHRKKWIAAJSAO-UHFFFAOYSA-N rapamycin Natural products COCC(O)C(=C/C(C)C(=O)CC(OC(=O)C1CCCCN1C(=O)C(=O)C2(O)OC(CC(OC)C(=CC=CC=CC(C)CC(C)C(=O)C)C)CCC2C)C(C)CC3CCC(O)C(C3)OC)C ZAHRKKWIAAJSAO-UHFFFAOYSA-N 0.000 claims 2
- QFJCIRLUMZQUOT-HPLJOQBZSA-N sirolimus Chemical compound C1C[C@@H](O)[C@H](OC)C[C@@H]1C[C@@H](C)[C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@](O)(O2)[C@H](C)CC[C@H]2C[C@H](OC)/C(C)=C/C=C/C=C/[C@@H](C)C[C@@H](C)C(=O)[C@H](OC)[C@H](O)/C(C)=C/[C@@H](C)C(=O)C1 QFJCIRLUMZQUOT-HPLJOQBZSA-N 0.000 claims 2
- 229960002930 sirolimus Drugs 0.000 claims 2
- 210000000329 smooth muscle myocyte Anatomy 0.000 claims 2
- 125000003011 styrenyl group Chemical group [H]\C(*)=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[H] 0.000 claims 2
- 229960001967 tacrolimus Drugs 0.000 claims 2
- QJJXYPPXXYFBGM-SHYZHZOCSA-N tacrolimus Natural products CO[C@H]1C[C@H](CC[C@@H]1O)C=C(C)[C@H]2OC(=O)[C@H]3CCCCN3C(=O)C(=O)[C@@]4(O)O[C@@H]([C@H](C[C@H]4C)OC)[C@@H](C[C@H](C)CC(=C[C@@H](CC=C)C(=O)C[C@H](O)[C@H]2C)C)OC QJJXYPPXXYFBGM-SHYZHZOCSA-N 0.000 claims 2
- RCINICONZNJXQF-MZXODVADSA-N taxol Chemical compound O([C@@H]1[C@@]2(C[C@@H](C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3([C@H]21)OC(C)=O)=O)OC(=O)C)OC(=O)[C@H](O)[C@@H](NC(=O)C=1C=CC=CC=1)C=1C=CC=CC=1)O)C(=O)C1=CC=CC=C1 RCINICONZNJXQF-MZXODVADSA-N 0.000 claims 2
- 229920000642 polymer Polymers 0.000 claims 1
- 125000000383 tetramethylene group Chemical group [H]C([H])([*:1])C([H])([H])C([H])([H])C([H])([H])[*:2] 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11/409,468 US7879086B2 (en) | 2006-04-20 | 2006-04-20 | Medical device having a coating comprising an adhesion promoter |
| PCT/US2007/009805 WO2007124137A1 (en) | 2006-04-20 | 2007-04-19 | Medical device having a coating comprising an adhesion promoter |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009534109A JP2009534109A (ja) | 2009-09-24 |
| JP2009534109A5 true JP2009534109A5 (enExample) | 2012-07-12 |
Family
ID=38434734
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009506630A Pending JP2009534109A (ja) | 2006-04-20 | 2007-04-19 | 接着促進剤を含むコーティングを有する医療デバイス |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US7879086B2 (enExample) |
| EP (1) | EP2010243A1 (enExample) |
| JP (1) | JP2009534109A (enExample) |
| CA (1) | CA2649695A1 (enExample) |
| WO (1) | WO2007124137A1 (enExample) |
Families Citing this family (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7713297B2 (en) | 1998-04-11 | 2010-05-11 | Boston Scientific Scimed, Inc. | Drug-releasing stent with ceramic-containing layer |
| ES2691646T3 (es) | 2005-07-15 | 2018-11-28 | Micell Technologies, Inc. | Revestimientos poliméricos que contienen polvo de fármaco de morfología controlada |
| US20070224235A1 (en) | 2006-03-24 | 2007-09-27 | Barron Tenney | Medical devices having nanoporous coatings for controlled therapeutic agent delivery |
| US8187620B2 (en) | 2006-03-27 | 2012-05-29 | Boston Scientific Scimed, Inc. | Medical devices comprising a porous metal oxide or metal material and a polymer coating for delivering therapeutic agents |
| US8852625B2 (en) | 2006-04-26 | 2014-10-07 | Micell Technologies, Inc. | Coatings containing multiple drugs |
| US20070264303A1 (en) * | 2006-05-12 | 2007-11-15 | Liliana Atanasoska | Coating for medical devices comprising an inorganic or ceramic oxide and a therapeutic agent |
| US8815275B2 (en) | 2006-06-28 | 2014-08-26 | Boston Scientific Scimed, Inc. | Coatings for medical devices comprising a therapeutic agent and a metallic material |
| US8771343B2 (en) | 2006-06-29 | 2014-07-08 | Boston Scientific Scimed, Inc. | Medical devices with selective titanium oxide coatings |
| WO2008022258A2 (en) * | 2006-08-16 | 2008-02-21 | Surmodics, Inc. | Methods and materials for increasing the adhesion of elution control matrices to substrates |
| ATE508708T1 (de) | 2006-09-14 | 2011-05-15 | Boston Scient Ltd | Medizinprodukte mit wirkstofffreisetzender beschichtung |
| US7981150B2 (en) | 2006-11-09 | 2011-07-19 | Boston Scientific Scimed, Inc. | Endoprosthesis with coatings |
| US8431149B2 (en) | 2007-03-01 | 2013-04-30 | Boston Scientific Scimed, Inc. | Coated medical devices for abluminal drug delivery |
| US8070797B2 (en) | 2007-03-01 | 2011-12-06 | Boston Scientific Scimed, Inc. | Medical device with a porous surface for delivery of a therapeutic agent |
| US7914807B2 (en) | 2007-03-05 | 2011-03-29 | Boston Scientific Scimed, Inc. | Medical devices having improved performance |
| US8067054B2 (en) | 2007-04-05 | 2011-11-29 | Boston Scientific Scimed, Inc. | Stents with ceramic drug reservoir layer and methods of making and using the same |
| SG183035A1 (en) * | 2007-04-17 | 2012-08-30 | Micell Technologies Inc | Stents having biodegradable layers |
| US7976915B2 (en) | 2007-05-23 | 2011-07-12 | Boston Scientific Scimed, Inc. | Endoprosthesis with select ceramic morphology |
| US8425591B1 (en) | 2007-06-11 | 2013-04-23 | Abbott Cardiovascular Systems Inc. | Methods of forming polymer-bioceramic composite medical devices with bioceramic particles |
| US8002823B2 (en) | 2007-07-11 | 2011-08-23 | Boston Scientific Scimed, Inc. | Endoprosthesis coating |
| US7942926B2 (en) | 2007-07-11 | 2011-05-17 | Boston Scientific Scimed, Inc. | Endoprosthesis coating |
| US9284409B2 (en) | 2007-07-19 | 2016-03-15 | Boston Scientific Scimed, Inc. | Endoprosthesis having a non-fouling surface |
| US8815273B2 (en) | 2007-07-27 | 2014-08-26 | Boston Scientific Scimed, Inc. | Drug eluting medical devices having porous layers |
| US7931683B2 (en) | 2007-07-27 | 2011-04-26 | Boston Scientific Scimed, Inc. | Articles having ceramic coated surfaces |
| US8221822B2 (en) | 2007-07-31 | 2012-07-17 | Boston Scientific Scimed, Inc. | Medical device coating by laser cladding |
| EP2185103B1 (en) | 2007-08-03 | 2014-02-12 | Boston Scientific Scimed, Inc. | Coating for medical device having increased surface area |
| US8029554B2 (en) | 2007-11-02 | 2011-10-04 | Boston Scientific Scimed, Inc. | Stent with embedded material |
| US7938855B2 (en) | 2007-11-02 | 2011-05-10 | Boston Scientific Scimed, Inc. | Deformable underlayer for stent |
| US8216632B2 (en) | 2007-11-02 | 2012-07-10 | Boston Scientific Scimed, Inc. | Endoprosthesis coating |
| US8535358B2 (en) | 2007-11-19 | 2013-09-17 | Medical Facets, Llc | Bone screw and method for manufacturing the same |
| US8112870B2 (en) | 2007-11-19 | 2012-02-14 | Medical Facets Llc | Bone screw and method for manufacturing the same |
| JP5581311B2 (ja) | 2008-04-22 | 2014-08-27 | ボストン サイエンティフィック サイムド，インコーポレイテッド | 無機材料のコーティングを有する医療デバイス及びその製造方法 |
| WO2009132176A2 (en) | 2008-04-24 | 2009-10-29 | Boston Scientific Scimed, Inc. | Medical devices having inorganic particle layers |
| US9220811B2 (en) * | 2008-09-22 | 2015-12-29 | Boston Scientific Scimed, Inc. | Implantable or insertable medical devices |
| US8231980B2 (en) | 2008-12-03 | 2012-07-31 | Boston Scientific Scimed, Inc. | Medical implants including iridium oxide |
| US8071156B2 (en) | 2009-03-04 | 2011-12-06 | Boston Scientific Scimed, Inc. | Endoprostheses |
| US8287937B2 (en) | 2009-04-24 | 2012-10-16 | Boston Scientific Scimed, Inc. | Endoprosthese |
| CN102274550B (zh) | 2010-06-13 | 2014-11-26 | 上海微创医疗器械（集团）有限公司 | 一种介入医疗器械 |
| PT2811926T (pt) | 2012-02-09 | 2019-06-06 | Orthopedic Medical Channels Llc | Parafuso ósseo |
| LT2814402T (lt) | 2012-02-13 | 2018-12-27 | Medical Facets Llc | Briaunuotas kaulų varžtas |
| CN110003715B (zh) * | 2019-03-27 | 2021-08-10 | 山东华诺日化有限公司 | 一种塑料编织袋印刷用醇溶性墨水及其制备方法 |
| CN116173381A (zh) * | 2022-12-19 | 2023-05-30 | 上海百心安生物技术股份有限公司 | 一种新型可控制药物释放的药物球囊导管及其应用 |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE445884B (sv) | 1982-04-30 | 1986-07-28 | Medinvent Sa | Anordning for implantation av en rorformig protes |
| SE453258B (sv) | 1986-04-21 | 1988-01-25 | Medinvent Sa | Elastisk, sjelvexpanderande protes samt forfarande for dess framstellning |
| KR960700025A (ko) | 1993-01-19 | 1996-01-19 | 알렌 제이.스피겔 | 피복 복합 스텐트(clad composite stent) |
| US5449373A (en) | 1994-03-17 | 1995-09-12 | Medinol Ltd. | Articulated stent |
| US6099562A (en) | 1996-06-13 | 2000-08-08 | Schneider (Usa) Inc. | Drug coating with topcoat |
| US6790228B2 (en) * | 1999-12-23 | 2004-09-14 | Advanced Cardiovascular Systems, Inc. | Coating for implantable devices and a method of forming the same |
| US6908624B2 (en) * | 1999-12-23 | 2005-06-21 | Advanced Cardiovascular Systems, Inc. | Coating for implantable devices and a method of forming the same |
| US6398807B1 (en) | 2000-01-31 | 2002-06-04 | Scimed Life Systems, Inc. | Braided branching stent, method for treating a lumen therewith, and process for manufacture therefor |
| US6939376B2 (en) * | 2001-11-05 | 2005-09-06 | Sun Biomedical, Ltd. | Drug-delivery endovascular stent and method for treating restenosis |
| US7951392B2 (en) * | 2002-08-16 | 2011-05-31 | Boston Scientific Scimed, Inc. | Microarray drug delivery coatings |
| US20040059409A1 (en) | 2002-09-24 | 2004-03-25 | Stenzel Eric B. | Method of applying coatings to a medical device |
| AU2003279962A1 (en) | 2002-10-22 | 2004-05-13 | Medtronic Vascular Inc. | Stent with intermittent coating |
| US20040230298A1 (en) * | 2003-04-25 | 2004-11-18 | Medtronic Vascular, Inc. | Drug-polymer coated stent with polysulfone and styrenic block copolymer |
| US20040225345A1 (en) * | 2003-05-05 | 2004-11-11 | Fischell Robert E. | Means and method for stenting bifurcated vessels |
| US20040236416A1 (en) * | 2003-05-20 | 2004-11-25 | Robert Falotico | Increased biocompatibility of implantable medical devices |
| US20040260318A1 (en) * | 2003-05-23 | 2004-12-23 | Angiotech International Ag | Anastomotic connector devices |
| DE10329260A1 (de) | 2003-06-23 | 2005-01-13 | Biotronik Meß- und Therapiegeräte GmbH & Co. Ingenieurbüro Berlin | Stent mit einem Beschichtungssystem |
| WO2005007035A1 (en) | 2003-07-07 | 2005-01-27 | Medtronic Vascular | Coated stent with timed release of multiple therapeutic agents to inhibit restenosis adjacent to the stent ends |
| US7357940B2 (en) * | 2003-07-31 | 2008-04-15 | Boston Scientific Scimed, Inc. | Implantable or insertable medical devices containing graft copolymer for controlled delivery of therapeutic agents |
| US20050064011A1 (en) * | 2003-08-11 | 2005-03-24 | Young-Ho Song | Implantable or insertable medical devices containing phenolic compound for inhibition of restenosis |
| US20050228477A1 (en) * | 2004-04-09 | 2005-10-13 | Xtent, Inc. | Topographic coatings and coating methods for medical devices |
| US8697119B2 (en) * | 2004-07-19 | 2014-04-15 | Boston Scientific Scimed, Inc. | Medical devices and materials containing isobutylene copolymer |
| US20060093643A1 (en) | 2004-11-04 | 2006-05-04 | Stenzel Eric B | Medical device for delivering therapeutic agents over different time periods |
| US7935379B2 (en) * | 2005-11-14 | 2011-05-03 | Boston Scientific Scimed, Inc. | Coated and imprinted medical devices and methods of making the same |
-
2006
- 2006-04-20 US US11/409,468 patent/US7879086B2/en not_active Expired - Fee Related
-
2007
- 2007-04-19 WO PCT/US2007/009805 patent/WO2007124137A1/en not_active Ceased
- 2007-04-19 EP EP07755889A patent/EP2010243A1/en not_active Withdrawn
- 2007-04-19 CA CA002649695A patent/CA2649695A1/en not_active Abandoned
- 2007-04-19 JP JP2009506630A patent/JP2009534109A/ja active Pending
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