|
US4489710A
(en)
|
1981-06-23 |
1984-12-25 |
Xoma Corporation |
Composition and method for transplantation therapy
|
|
US4429008B1
(en)
|
1981-12-10 |
1995-05-16 |
Univ California |
Thiol reactive liposomes
|
|
US4769330A
(en)
|
1981-12-24 |
1988-09-06 |
Health Research, Incorporated |
Modified vaccinia virus and methods for making and using the same
|
|
US4603112A
(en)
|
1981-12-24 |
1986-07-29 |
Health Research, Incorporated |
Modified vaccinia virus
|
|
US4671958A
(en)
|
1982-03-09 |
1987-06-09 |
Cytogen Corporation |
Antibody conjugates for the delivery of compounds to target sites
|
|
JPS59116229A
(ja)
|
1982-12-24 |
1984-07-05 |
Teijin Ltd |
細胞毒性複合体を活性成分とする癌治療用剤およびその製造法
|
|
GB8308235D0
(en)
|
1983-03-25 |
1983-05-05 |
Celltech Ltd |
Polypeptides
|
|
US4816567A
(en)
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
|
US4673562A
(en)
|
1983-08-19 |
1987-06-16 |
The Children's Medical Center Corporation |
Bisamide bisthiol compounds useful for making technetium radiodiagnostic renal agents
|
|
US4873088A
(en)
|
1983-09-06 |
1989-10-10 |
Liposome Technology, Inc. |
Liposome drug delivery method and composition
|
|
US4625014A
(en)
|
1984-07-10 |
1986-11-25 |
Dana-Farber Cancer Institute, Inc. |
Cell-delivery agent
|
|
US4542225A
(en)
|
1984-08-29 |
1985-09-17 |
Dana-Farber Cancer Institute, Inc. |
Acid-cleavable compound
|
|
US4638045A
(en)
|
1985-02-19 |
1987-01-20 |
Massachusetts Institute Of Technology |
Non-peptide polyamino acid bioerodible polymers
|
|
US4683202A
(en)
|
1985-03-28 |
1987-07-28 |
Cetus Corporation |
Process for amplifying nucleic acid sequences
|
|
GB8508845D0
(en)
|
1985-04-04 |
1985-05-09 |
Hoffmann La Roche |
Vaccinia dna
|
|
US4777127A
(en)
|
1985-09-30 |
1988-10-11 |
Labsystems Oy |
Human retrovirus-related products and methods of diagnosing and treating conditions associated with said retrovirus
|
|
CA1293460C
(en)
|
1985-10-07 |
1991-12-24 |
Brian Lee Sauer |
Site-specific recombination of dna in yeast
|
|
US4699784A
(en)
|
1986-02-25 |
1987-10-13 |
Center For Molecular Medicine & Immunology |
Tumoricidal methotrexate-antibody conjugate
|
|
US6071517A
(en)
|
1986-07-07 |
2000-06-06 |
Medarex, Inc. |
Bispecific heteroantibodies with dual effector functions
|
|
US5635600A
(en)
|
1986-07-07 |
1997-06-03 |
Trustees Of Dartmouth College |
Bifunctional and heteroantibodies specific for the high affinity Fc receptor for immunoglobulin G on human mononuclear phagocytes
|
|
US5567610A
(en)
|
1986-09-04 |
1996-10-22 |
Bioinvent International Ab |
Method of producing human monoclonal antibodies and kit therefor
|
|
US6024983A
(en)
|
1986-10-24 |
2000-02-15 |
Southern Research Institute |
Composition for delivering bioactive agents for immune response and its preparation
|
|
US5075109A
(en)
|
1986-10-24 |
1991-12-24 |
Southern Research Institute |
Method of potentiating an immune response
|
|
US4987071A
(en)
|
1986-12-03 |
1991-01-22 |
University Patents, Inc. |
RNA ribozyme polymerases, dephosphorylases, restriction endoribonucleases and methods
|
|
GB8702816D0
(en)
|
1987-02-07 |
1987-03-11 |
Al Sumidaie A M K |
Obtaining retrovirus-containing fraction
|
|
US5219740A
(en)
|
1987-02-13 |
1993-06-15 |
Fred Hutchinson Cancer Research Center |
Retroviral gene transfer into diploid fibroblasts for gene therapy
|
|
US4735792A
(en)
|
1987-04-28 |
1988-04-05 |
The United States Of America As Represented By The United States Department Of Energy |
Radioiodinated maleimides and use as agents for radiolabeling antibodies
|
|
US4897268A
(en)
|
1987-08-03 |
1990-01-30 |
Southern Research Institute |
Drug delivery system and method of making the same
|
|
WO1989001973A2
(en)
|
1987-09-02 |
1989-03-09 |
Applied Biotechnology, Inc. |
Recombinant pox virus for immunization against tumor-associated antigens
|
|
AP129A
(en)
|
1988-06-03 |
1991-04-17 |
Smithkline Biologicals S A |
Expression of retrovirus gag protein eukaryotic cells
|
|
CA1340323C
(en)
|
1988-09-20 |
1999-01-19 |
Arnold E. Hampel |
Rna catalyst for cleaving specific rna sequences
|
|
GB8823869D0
(en)
|
1988-10-12 |
1988-11-16 |
Medical Res Council |
Production of antibodies
|
|
US5175384A
(en)
|
1988-12-05 |
1992-12-29 |
Genpharm International |
Transgenic mice depleted in mature t-cells and methods for making transgenic mice
|
|
DK0471036T4
(da)
|
1989-05-04 |
2004-07-19 |
Southern Res Inst |
Indkapslingsfremgangsmåde
|
|
US5725871A
(en)
|
1989-08-18 |
1998-03-10 |
Danbiosyst Uk Limited |
Drug delivery compositions comprising lysophosphoglycerolipid
|
|
AU648261B2
(en)
|
1989-08-18 |
1994-04-21 |
Novartis Vaccines And Diagnostics, Inc. |
Recombinant retroviruses delivering vector constructs to target cells
|
|
KR920007887B1
(ko)
|
1989-08-29 |
1992-09-18 |
스즈키 지도오샤 고오교오 가부시키가이샤 |
내연기관의 배기가스 정화장치
|
|
AU637800B2
(en)
|
1989-08-31 |
1993-06-10 |
City Of Hope |
Chimeric dna-rna catalytic sequences
|
|
US5707644A
(en)
|
1989-11-04 |
1998-01-13 |
Danbiosyst Uk Limited |
Small particle compositions for intranasal drug delivery
|
|
US5229275A
(en)
|
1990-04-26 |
1993-07-20 |
Akzo N.V. |
In-vitro method for producing antigen-specific human monoclonal antibodies
|
|
US6365730B1
(en)
|
1990-06-19 |
2002-04-02 |
Gene Shears Pty. Limited |
DNA-Armed ribozymes and minizymes
|
|
US5770429A
(en)
|
1990-08-29 |
1998-06-23 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
ES2061416T3
(es)
|
1990-10-12 |
1997-03-01 |
Max Planck Gesellschaft |
Ribozimas modificadas.
|
|
DE4216134A1
(de)
|
1991-06-20 |
1992-12-24 |
Europ Lab Molekularbiolog |
Synthetische katalytische oligonukleotidstrukturen
|
|
US5565332A
(en)
|
1991-09-23 |
1996-10-15 |
Medical Research Council |
Production of chimeric antibodies - a combinatorial approach
|
|
US5756353A
(en)
|
1991-12-17 |
1998-05-26 |
The Regents Of The University Of California |
Expression of cloned genes in the lung by aerosol-and liposome-based delivery
|
|
WO1993015191A1
(en)
|
1992-01-24 |
1993-08-05 |
Life Technologies, Inc. |
Modulation of enzyme activities in the in vivo cloning of dna
|
|
US5652094A
(en)
|
1992-01-31 |
1997-07-29 |
University Of Montreal |
Nucleozymes
|
|
WO1993016177A1
(en)
|
1992-02-11 |
1993-08-19 |
Cell Genesys, Inc. |
Homogenotization of gene-targeting events
|
|
US5573905A
(en)
|
1992-03-30 |
1996-11-12 |
The Scripps Research Institute |
Encoded combinatorial chemical libraries
|
|
US7416728B2
(en)
*
|
1992-05-08 |
2008-08-26 |
Kyto Biopharma, Inc. |
Growth blocking agents
|
|
CA2135277C
(en)
*
|
1992-05-08 |
2001-04-24 |
Alton C. Morgan, Jr. |
Anti-receptor agents to the vitamin b12/transcobalamin ii receptor
|
|
EP0642589A4
(en)
|
1992-05-11 |
1997-05-21 |
Ribozyme Pharm Inc |
METHOD AND REAGENT TO INHIBIT VIRAL REPLICATION.
|
|
ES2105262T3
(es)
|
1992-05-18 |
1997-10-16 |
Minnesota Mining & Mfg |
Dispositivo de suministro de farmaco a traves de las mucosas.
|
|
EP0786522A2
(en)
|
1992-07-17 |
1997-07-30 |
Ribozyme Pharmaceuticals, Inc. |
Enzymatic RNA molecules for treatment of stenotic conditions
|
|
DK0678034T3
(da)
|
1993-01-11 |
1999-11-08 |
Dana Farber Cancer Inst Inc |
Induktion af cytotoksiske T-lymfocytreaktioner
|
|
FR2702160B1
(fr)
|
1993-03-02 |
1995-06-02 |
Biovecteurs As |
Vecteurs particulaires synthétiques et procédé de préparation.
|
|
FR2704145B1
(fr)
|
1993-04-21 |
1995-07-21 |
Pasteur Institut |
Vecteur particulaire et composition pharmaceutique le contenant.
|
|
US5814618A
(en)
|
1993-06-14 |
1998-09-29 |
Basf Aktiengesellschaft |
Methods for regulating gene expression
|
|
JPH09500526A
(ja)
|
1993-06-14 |
1997-01-21 |
ベーアーエスエフ アクツィエンゲゼルシャフト |
テトラサイクリン反応性プロモーターによる真核細胞の遺伝子発現の厳密な制御
|
|
US5591317A
(en)
|
1994-02-16 |
1997-01-07 |
Pitts, Jr.; M. Michael |
Electrostatic device for water treatment
|
|
US5631359A
(en)
|
1994-10-11 |
1997-05-20 |
Ribozyme Pharmaceuticals, Inc. |
Hairpin ribozymes
|
|
AU692239B2
(en)
|
1994-03-07 |
1998-06-04 |
Medarex, Inc. |
Bispecific molecules having clinical utilities
|
|
US5840880A
(en)
|
1994-04-08 |
1998-11-24 |
Receptagen Corporation |
Receptor modulating agents
|
|
US5739287A
(en)
|
1994-04-08 |
1998-04-14 |
University Of Washington |
Biotinylated cobalamins
|
|
US5869465A
(en)
|
1994-04-08 |
1999-02-09 |
Receptagen Corporation |
Methods of receptor modulation and uses therefor
|
|
CA2187346C
(en)
|
1994-04-08 |
2010-06-29 |
A. Charles Morgan, Jr. |
Receptor modulating agents and methods relating thereto
|
|
FR2723849B1
(fr)
|
1994-08-31 |
1997-04-11 |
Biovector Therapeutics Sa |
Procede pour augmenter l'immunogenicite, produit obtenu et composition pharmaceutique
|
|
EP0783526B1
(en)
|
1994-09-13 |
2006-03-01 |
Kyto Biopharma, Inc. |
Growth blocking agents to the vitamin b12 binding sites on transcobalamin ii
|
|
US6111166A
(en)
|
1994-09-19 |
2000-08-29 |
Medarex, Incorporated |
Transgenic mice expressing human Fcα and β receptors
|
|
US5783683A
(en)
|
1995-01-10 |
1998-07-21 |
Genta Inc. |
Antisense oligonucleotides which reduce expression of the FGFRI gene
|
|
US6410690B1
(en)
|
1995-06-07 |
2002-06-25 |
Medarex, Inc. |
Therapeutic compounds comprised of anti-Fc receptor antibodies
|
|
US5747470A
(en)
|
1995-06-07 |
1998-05-05 |
Gen-Probe Incorporated |
Method for inhibiting cellular proliferation using antisense oligonucleotides to gp130 mRNA
|
|
ES2176484T3
(es)
|
1995-08-18 |
2002-12-01 |
Morphosys Ag |
Bancos de proteinas/(poli)peptidos.
|
|
US7264963B1
(en)
|
1995-08-18 |
2007-09-04 |
Morphosys Ag |
Protein(poly)peptide libraries
|
|
EP1015475A1
(en)
|
1995-10-19 |
2000-07-05 |
Receptagen Corporation |
Vitamin b 12? receptor modulating agents and methods related thereto
|
|
US5739313A
(en)
|
1995-11-13 |
1998-04-14 |
Regents Of The University Of Minnesota |
Radionuclide labeling of vitamin B12 and coenzymes thereof
|
|
US5922845A
(en)
|
1996-07-11 |
1999-07-13 |
Medarex, Inc. |
Therapeutic multispecific compounds comprised of anti-Fcα receptor antibodies
|
|
WO1999006587A2
(en)
|
1997-08-01 |
1999-02-11 |
Morphosys Ag |
Novel method and phage for the identification of nucleic acid sequences encoding members of a multimeric (poly)peptide complex
|
|
US20030092002A1
(en)
*
|
1997-09-17 |
2003-05-15 |
Genentech, Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
|
US6682928B2
(en)
|
1997-12-02 |
2004-01-27 |
Medarex, Inc. |
Cells expressing anti-Fc receptor binding components
|
|
US6506559B1
(en)
|
1997-12-23 |
2003-01-14 |
Carnegie Institute Of Washington |
Genetic inhibition by double-stranded RNA
|
|
CZ302092B6
(cs)
|
1998-02-12 |
2010-10-06 |
Immune Complex, Corporation |
Konjugát upraveného jaderného proteinu hepatitidy B, jeho cástice, inokulum a zpusob indukce protilátek
|
|
US6080576A
(en)
|
1998-03-27 |
2000-06-27 |
Lexicon Genetics Incorporated |
Vectors for gene trapping and gene activation
|
|
DE69940196D1
(de)
|
1998-04-15 |
2009-02-12 |
Hutchinson Fred Cancer Res |
Methoden und vektorenkonstrukte zur erzeugung von transgene nagetieren, welche ein heterologes gen ubiquitär exprimieren
|
|
US6753138B1
(en)
|
1998-06-04 |
2004-06-22 |
Reprogen, Inc. |
Use of prothymosin in the diagnosis and treatment of endometriosis
|
|
ES2327785T3
(es)
*
|
1998-12-22 |
2009-11-03 |
Genentech, Inc. |
Procedimientos y compuestos para inhibir el crecimiento de celulas neoplasticas.
|
|
NZ550899A
(en)
|
1999-01-13 |
2008-07-31 |
Revivicor Inc |
Double nuclear transfer method and the production of a non human animal thereby
|
|
US6231768B1
(en)
|
1999-01-19 |
2001-05-15 |
Nalco Chemical Company |
Rheology modification of settled solids in mineral processing
|
|
NZ514620A
(en)
|
1999-03-04 |
2004-04-30 |
Ppl Therapeutics Scotland Ltd |
Genetic modification of somatic cells and uses thereof
|
|
US6806363B1
(en)
|
1999-04-16 |
2004-10-19 |
Mayo Foundation For Medical Education & Research |
Cobalamin conjugates useful as antitumor agents
|
|
WO2001002588A2
(en)
|
1999-07-02 |
2001-01-11 |
Morphosys Ag |
Generation of specific binding partners binding to (poly)peptides encoded by genomic dna fragments or ests
|
|
EP1212422B1
(en)
|
1999-08-24 |
2007-02-21 |
Medarex, Inc. |
Human ctla-4 antibodies and their uses
|
|
JP2003531105A
(ja)
|
1999-10-15 |
2003-10-21 |
メイオウ・フアウンデーシヨン・フオー・メデイカル・エジユケイシヨン・アンド・リサーチ |
造影剤および治療薬として有用なコバラミン結合体
|
|
HK1047109A1
(zh)
|
1999-10-15 |
2003-02-07 |
University Of Massachusetts |
作为指定基因干预工具的rna干预轨迹基因
|
|
US20030180312A1
(en)
*
|
2000-02-22 |
2003-09-25 |
Genentech, Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
|
EP1272630A2
(en)
|
2000-03-16 |
2003-01-08 |
Genetica, Inc. |
Methods and compositions for rna interference
|
|
ES2336887T5
(es)
|
2000-03-30 |
2019-03-06 |
Whitehead Inst Biomedical Res |
Mediadores de interferencia por ARN específicos de secuencias de ARN
|
|
WO2001092513A1
(en)
|
2000-05-30 |
2001-12-06 |
Johnson & Johnson Research Pty Limited |
METHODS FOR MEDIATING GENE SUPPRESION BY USING FACTORS THAT ENHANCE RNAi
|
|
AU2001275474A1
(en)
|
2000-06-12 |
2001-12-24 |
Akkadix Corporation |
Materials and methods for the control of nematodes
|
|
CA2429814C
(en)
|
2000-12-01 |
2014-02-18 |
Thomas Tuschl |
Rna interference mediating small rna molecules
|
|
CA2505849C
(en)
|
2002-07-30 |
2013-11-05 |
Morphosys Ip Gmbh |
Novel tricistronic vectors and uses therefor
|
|
CA2505995C
(en)
*
|
2002-11-26 |
2012-04-17 |
Axis-Shield Asa |
Cobalamin assay
|
|
WO2007117657A2
(en)
|
2006-04-07 |
2007-10-18 |
The Research Foundation Of State University Of New York |
Transcobalamin receptor polypeptides, nucleic acids, and modulators thereof, and related methods of use in modulating cell growth and treating cancer and cobalamin deficiency
|
|
US20100239592A1
(en)
*
|
2009-02-13 |
2010-09-23 |
New York Methodist Hospital |
Methods of analysis and detecting molecular defects in transcobalamin i deficiency
|