JP2009530401A5 - - Google Patents

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Publication number
JP2009530401A5
JP2009530401A5 JP2009501581A JP2009501581A JP2009530401A5 JP 2009530401 A5 JP2009530401 A5 JP 2009530401A5 JP 2009501581 A JP2009501581 A JP 2009501581A JP 2009501581 A JP2009501581 A JP 2009501581A JP 2009530401 A5 JP2009530401 A5 JP 2009530401A5
Authority
JP
Japan
Prior art keywords
compound
mif
sepsis
disease
mammal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
JP2009501581A
Other languages
English (en)
Japanese (ja)
Other versions
JP2009530401A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2007/007277 external-priority patent/WO2007112015A2/en
Publication of JP2009530401A publication Critical patent/JP2009530401A/ja
Publication of JP2009530401A5 publication Critical patent/JP2009530401A5/ja
Ceased legal-status Critical Current

Links

JP2009501581A 2006-03-24 2007-03-23 フェノールヒドラゾンマクロファージ転移阻害因子阻害剤 Ceased JP2009530401A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US78583406P 2006-03-24 2006-03-24
PCT/US2007/007277 WO2007112015A2 (en) 2006-03-24 2007-03-23 Phenolic hydrazone macrophage migration inhibitory factor inhibitors

Publications (2)

Publication Number Publication Date
JP2009530401A JP2009530401A (ja) 2009-08-27
JP2009530401A5 true JP2009530401A5 (enExample) 2013-03-21

Family

ID=38541686

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009501581A Ceased JP2009530401A (ja) 2006-03-24 2007-03-23 フェノールヒドラゾンマクロファージ転移阻害因子阻害剤

Country Status (6)

Country Link
US (2) US8193247B2 (enExample)
EP (1) EP2004649B1 (enExample)
JP (1) JP2009530401A (enExample)
AU (1) AU2007231012B2 (enExample)
CA (1) CA2647045A1 (enExample)
WO (1) WO2007112015A2 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5523095B2 (ja) * 2006-03-24 2014-06-18 ザ・フェインスタイン・インスティチュート・フォー・メディカル・リサーチ 修飾マクロファージ遊走阻止因子阻害剤
EP2287149A1 (en) * 2009-08-20 2011-02-23 Max-Delbrück-Centrum Für Molekulare Medizin Enhancers of protein degradation
US8703749B2 (en) 2009-12-07 2014-04-22 Roberto Testi Compositions and methods for treating Friedreich's Ataxia
US9567306B2 (en) 2014-06-17 2017-02-14 The Feinstein Institute For Medical Research Inhibition of macrophage migration inhibitory factor in melanoma and colon cancer
CN104402771B (zh) * 2014-11-26 2016-09-28 玉林师范学院 对羟基苯甲醛缩氨基脲的合成及在防治植物病害中的应用
EP3804706B1 (en) * 2015-05-29 2023-08-23 Emory University 2-amino-n'-benzylideneacetohydrazides and derivatives for the management of cftr protein mediated diseases
US10512636B2 (en) 2015-05-29 2019-12-24 Emory University 3-(phenyl)-N-(4-phenoxybenzyl)-1,2,4-oxadiazole-5-carboxamide compounds for the management of CFTR protein mediated diseases
JP2018534303A (ja) * 2015-11-12 2018-11-22 ザ・トラスティーズ・オブ・コロンビア・ユニバーシティ・イン・ザ・シティ・オブ・ニューヨーク ポリミキシン系抗生物質に対する耐性グラム陰性細菌感染を標的にする合理的薬物設計
WO2020067477A1 (ja) * 2018-09-28 2020-04-02 日産化学株式会社 パラクライン因子生産促進用培地添加剤
CN111909082B (zh) * 2019-05-07 2022-09-13 湖南大学 吡啶腙衍生物及其制备方法与应用
CN110229081B (zh) * 2019-07-01 2022-02-08 长沙理工大学 2,4-二硝基苯腙衍生物及其制备方法与应用
EP4237002A4 (en) * 2020-10-28 2025-02-12 University Health Network METHODS OF TREATING SPONDYLOARTHRITIS OR SYMPTOMS THEREOF

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58189192A (ja) * 1982-04-22 1983-11-04 Nissan Chem Ind Ltd 有機リン酸エステル誘導体、その製法及びこれらを含有する有害生物防除剤
US5753652A (en) * 1991-07-03 1998-05-19 Novartis Corporation Antiretroviral hydrazine derivatives
US6080407A (en) * 1993-05-17 2000-06-27 The Picower Institute For Medical Research Diagnostic assays for MIF
JP3529491B2 (ja) * 1995-05-16 2004-05-24 旭電化工業株式会社 感熱記録材料
EP0839669A1 (en) 1996-11-05 1998-05-06 Asahi Denka Kogyo Kabushiki Kaisha Heat-sensitive recording meterial
DE19817262A1 (de) * 1998-04-18 1999-10-21 Bayer Ag Neue 2-heterocyclisch substituierte Dihydropyrimidine
EP1228037A4 (en) * 1999-10-29 2004-06-02 Picower Inst Med Res COMPOUNDS HAVING ANTIAGONIST ACTIVITY OF MIF
WO2001047923A1 (en) 1999-12-23 2001-07-05 Astrazeneca Ab Compounds and methods for the treatment of pain
US6503914B1 (en) 2000-10-23 2003-01-07 Board Of Regents, The University Of Texas System Thienopyrimidine-based inhibitors of the Src family
CA2450589C (en) 2001-06-08 2011-12-20 Cytokine Pharmasciences, Inc. Isoxazoline compounds having mif antagonist activity
AU2003261204A1 (en) * 2002-07-23 2004-02-09 Smithkline Beecham Corporation Pyrazolopyrimidines as kinase inhibitors
JP2006514918A (ja) 2002-07-23 2006-05-18 スミスクライン ビーチャム コーポレーション キナーゼインヒビターとしてのピラゾロピリミジン
US20060276433A1 (en) * 2003-03-31 2006-12-07 Keiichi Kawagoe Hydrazone derivative
DE10346913A1 (de) 2003-10-09 2005-05-04 Merck Patent Gmbh Acylhydrazonderivate
DE10348022A1 (de) 2003-10-15 2005-05-25 Imtm Gmbh Neue Dipeptidylpeptidase IV-Inhibitoren zur funktionellen Beeinflussung unterschiedlicher Zellen und zur Behandlung immunologischer, entzündlicher, neuronaler und anderer Erkrankungen
CA2558810A1 (en) 2004-03-08 2005-09-15 Florian Lang Methods for altering insulin secretion
BRPI0509282A (pt) * 2004-03-30 2007-09-18 Univ California compostos contendo hidrazida inibidores de cftr e seus usos
US20060004002A1 (en) * 2004-07-02 2006-01-05 Thomas Thrash Small molecule thienopyrimidine-based protein tyrosine kinase inhibitors
RU2007125278A (ru) * 2005-02-08 2009-03-20 Зе Скрипс Ресеч Инститьют (Us) Ингибиторы образования амилоидных волокон транстиретина

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