JP2009529553A5 - - Google Patents
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- JP2009529553A5 JP2009529553A5 JP2008558710A JP2008558710A JP2009529553A5 JP 2009529553 A5 JP2009529553 A5 JP 2009529553A5 JP 2008558710 A JP2008558710 A JP 2008558710A JP 2008558710 A JP2008558710 A JP 2008558710A JP 2009529553 A5 JP2009529553 A5 JP 2009529553A5
- Authority
- JP
- Japan
- Prior art keywords
- phe
- cys
- glu
- gly
- ala
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP06360008 | 2006-03-16 | ||
| EP06360008.4 | 2006-03-16 | ||
| EP06291516 | 2006-09-26 | ||
| EP06291516.0 | 2006-09-26 | ||
| PCT/EP2007/002216 WO2007104541A2 (en) | 2006-03-16 | 2007-03-13 | Compositions and methods using serine protease inhibiting peptides for treating ophthalmic disorders |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012171140A Division JP2012211194A (ja) | 2006-03-16 | 2012-08-01 | セリンプロテアーゼを阻害するペプチドを用いて眼科障害を治療する組成物及び方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009529553A JP2009529553A (ja) | 2009-08-20 |
| JP2009529553A5 true JP2009529553A5 (enExample) | 2011-03-10 |
| JP5337493B2 JP5337493B2 (ja) | 2013-11-06 |
Family
ID=38292592
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008558710A Active JP5337493B2 (ja) | 2006-03-16 | 2007-03-13 | セリンプロテアーゼを阻害するペプチドを用いて眼科障害を治療する組成物及び方法 |
| JP2012171140A Withdrawn JP2012211194A (ja) | 2006-03-16 | 2012-08-01 | セリンプロテアーゼを阻害するペプチドを用いて眼科障害を治療する組成物及び方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012171140A Withdrawn JP2012211194A (ja) | 2006-03-16 | 2012-08-01 | セリンプロテアーゼを阻害するペプチドを用いて眼科障害を治療する組成物及び方法 |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US20070270344A1 (enExample) |
| JP (2) | JP5337493B2 (enExample) |
| AU (1) | AU2007224643B2 (enExample) |
| CA (1) | CA2646285C (enExample) |
| DK (1) | DK1854477T3 (enExample) |
| ES (2) | ES2601554T3 (enExample) |
| HU (2) | HUE031701T2 (enExample) |
| LT (2) | LT2374472T (enExample) |
| PL (1) | PL1854477T3 (enExample) |
| PT (2) | PT2374472T (enExample) |
| SI (1) | SI2374472T1 (enExample) |
| WO (1) | WO2007104541A2 (enExample) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6057287A (en) | 1994-01-11 | 2000-05-02 | Dyax Corp. | Kallikrein-binding "Kunitz domain" proteins and analogues thereof |
| US20050222023A1 (en) * | 2002-02-07 | 2005-10-06 | Hans-Peter Hauser | Albumin-fused kunitz domain peptides |
| US7153829B2 (en) | 2002-06-07 | 2006-12-26 | Dyax Corp. | Kallikrein-inhibitor therapies |
| ATE528014T1 (de) | 2002-06-07 | 2011-10-15 | Dyax Corp | Polypeptid mit modifizierten kunitz domains |
| ES2447423T3 (es) * | 2003-08-29 | 2014-03-12 | Dyax Corp. | Inhibidores de proteasa poli-pegilados |
| US7235530B2 (en) | 2004-09-27 | 2007-06-26 | Dyax Corporation | Kallikrein inhibitors and anti-thrombolytic agents and uses thereof |
| EP1858542A4 (en) * | 2005-02-24 | 2009-08-19 | Joslin Diabetes Center Inc | COMPOSITIONS AND METHOD FOR THE TREATMENT OF VASPEREPERMABILITY |
| CA2635588C (en) | 2005-12-30 | 2015-11-10 | Dyax Corp. | Metalloproteinase binding proteins |
| ES2601554T3 (es) | 2006-03-16 | 2017-02-15 | Dyax Corp. | Péptidos inhibidores de calicreína plasmática para uso en el tratamiento de trastornos oftálmicos |
| US20100119512A1 (en) * | 2007-01-25 | 2010-05-13 | Joslin Diabetes Center | Methods of diagnosing, treating, and preventing increased vascular permeability |
| JP2011506614A (ja) | 2007-12-17 | 2011-03-03 | ダイアックス コーポレーション | Mmp−14結合タンパク質を含む、骨溶解性障害を処置するための組成物および方法 |
| EP2350305A4 (en) * | 2008-10-22 | 2013-03-06 | Dyax Corp | COMBINATION TREATMENTS WITH PROTEASE BINDING PROTEINS FOR INFLAMMATORY DISEASES |
| JP2013516389A (ja) | 2009-01-06 | 2013-05-13 | ダイアックス コーポレーション | カリクレイン阻害剤による粘膜炎治療 |
| ES2905545T3 (es) | 2010-01-06 | 2022-04-11 | Takeda Pharmaceuticals Co | Proteínas de unión a calicreína plasmática |
| IL269565B2 (en) | 2011-01-06 | 2024-06-01 | Dyax Corp | Plasma kallikrein binding proteins |
| US10314909B2 (en) | 2011-10-21 | 2019-06-11 | Dyax Corp. | Combination therapy comprising an MMP-14 binding protein |
| GB2510407A (en) * | 2013-02-04 | 2014-08-06 | Kalvista Pharmaceuticals Ltd | Aqueous suspensions of kallikrein inhibitors for parenteral administration |
| EP2970502A4 (en) | 2013-03-15 | 2016-11-30 | Dyax Corp | ANTI-PLASMA KALLIKREIN ANTIBODY |
| SG11201602889TA (en) | 2013-10-28 | 2016-05-30 | Bicycle Therapeutics Ltd | Novel polypeptides |
| KR102424183B1 (ko) | 2014-01-21 | 2022-07-26 | 다케다 파머수티컬 컴패니 리미티드 | 혈장 칼리크레인 결합 단백질 및 유전성 혈관부종을 치료하는 데 있어서의 이의 용도 |
| EP3122782A4 (en) | 2014-03-27 | 2017-09-13 | Dyax Corp. | Compositions and methods for treatment of diabetic macular edema |
| US10891729B2 (en) * | 2015-11-18 | 2021-01-12 | University Of Louisville Research Foundation, Inc. | Automated methods for the objective quantification of retinal characteristics by retinal region and diagnosis of retinal pathology |
| RU2622031C1 (ru) * | 2015-12-07 | 2017-06-08 | Государственное бюджетное образовательное учреждение высшего профессионального образования "Дагестанская государственная медицинская академия" Министерства здравоохранения РФ | Способ комбинированного лечения макулярного отека сетчатки |
| CN116077648A (zh) | 2015-12-11 | 2023-05-09 | 武田药品工业株式会社 | 血浆激肽释放酶抑制剂及其治疗遗传性血管性水肿发作的用途 |
| GB201522441D0 (en) * | 2015-12-18 | 2016-02-03 | Midatech Pharma Wales Ltd | Sustained release cyclosporine-loaded microparticles |
| JP7668227B2 (ja) * | 2019-04-08 | 2025-04-24 | バイオクライスト ファーマシューティカルズ, インコーポレイテッド | 血漿カリクレイン阻害剤および眼障害におけるその使用方法 |
| WO2021028645A1 (en) | 2019-08-09 | 2021-02-18 | Kalvista Pharmaceuticals Limited | Plasma kallikrein inhibitors |
| WO2021198534A1 (en) | 2020-04-04 | 2021-10-07 | Oxurion NV | Plasma kallikrein inhibitors for use in the treatment of coronaviral disease |
| LT6899B (lt) * | 2020-08-27 | 2022-04-11 | Valstybinis mokslinių tyrimų institutas Fizinių ir technologijos mokslų centras | Vario paviršiaus cheminio nikeliavimo būdas, nenaudojant aktyvavimo paladžiu |
| WO2023144030A1 (en) | 2022-01-31 | 2023-08-03 | Oxurion NV | Plasma kallikrein inhibitor therapy for anti-vegf sensitization |
| WO2023148016A1 (en) | 2022-02-04 | 2023-08-10 | Oxurion NV | Biomarker for plasma kallikrein inhibitor therapy response |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5444156A (en) * | 1985-07-12 | 1995-08-22 | Temple University-Of The Commonwealth System Of Higher Education | Monoclonal antibodies to human plasma prekallikrein |
| US5217951A (en) * | 1986-12-24 | 1993-06-08 | John Lezdey | Treatment of inflammation |
| ES2229236T3 (es) * | 1994-01-11 | 2005-04-16 | Dyax Corporation | Inhibidores de la plasmina humana derivados de los dominios de kunitz. |
| EP0739355B1 (en) * | 1994-01-11 | 2004-09-08 | Dyax Corporation | Kallikrein-inhibiting "kunitz domain" proteins and analogues thereof |
| US6057287A (en) * | 1994-01-11 | 2000-05-02 | Dyax Corp. | Kallikrein-binding "Kunitz domain" proteins and analogues thereof |
| US6174859B1 (en) * | 1999-04-06 | 2001-01-16 | J & D Sciences, Inc. | Method of treatment |
| DE10060653A1 (de) * | 2000-12-06 | 2002-06-20 | Epcos Ag | Elektrischer Doppelschicht-Kondensator |
| US20050222023A1 (en) * | 2002-02-07 | 2005-10-06 | Hans-Peter Hauser | Albumin-fused kunitz domain peptides |
| WO2003066824A2 (en) | 2002-02-07 | 2003-08-14 | Aventis Behring Gmbh | Albumin-fused kunitz domain peptides |
| ATE528014T1 (de) * | 2002-06-07 | 2011-10-15 | Dyax Corp | Polypeptid mit modifizierten kunitz domains |
| US7153829B2 (en) * | 2002-06-07 | 2006-12-26 | Dyax Corp. | Kallikrein-inhibitor therapies |
| EP1542710B1 (en) | 2002-08-28 | 2012-09-26 | Dyax Corp. | Methods for preserving organs and tissues |
| US6989369B2 (en) * | 2003-02-07 | 2006-01-24 | Dyax Corp. | Kunitz domain peptides |
| US20070020252A1 (en) * | 2003-08-29 | 2007-01-25 | Ladner Robert C | Modified protease inhibitors |
| ES2447423T3 (es) * | 2003-08-29 | 2014-03-12 | Dyax Corp. | Inhibidores de proteasa poli-pegilados |
| US7235530B2 (en) * | 2004-09-27 | 2007-06-26 | Dyax Corporation | Kallikrein inhibitors and anti-thrombolytic agents and uses thereof |
| EP1858542A4 (en) * | 2005-02-24 | 2009-08-19 | Joslin Diabetes Center Inc | COMPOSITIONS AND METHOD FOR THE TREATMENT OF VASPEREPERMABILITY |
| US7276480B1 (en) * | 2005-12-30 | 2007-10-02 | Dyax Corp. | Prevention and reduction of blood loss |
| WO2007106746A2 (en) | 2006-03-10 | 2007-09-20 | Dyax Corp. | Formulations for ecallantide |
| ES2601554T3 (es) | 2006-03-16 | 2017-02-15 | Dyax Corp. | Péptidos inhibidores de calicreína plasmática para uso en el tratamiento de trastornos oftálmicos |
| US8467792B2 (en) * | 2006-06-27 | 2013-06-18 | Qualcomm Incorporated | Method and apparatus for maintaining call continuity in wireless communication |
| WO2009026334A2 (en) | 2007-08-21 | 2009-02-26 | Genzyme Corporation | Treatment with kallikrein inhibitors |
| US20090105142A1 (en) * | 2007-08-23 | 2009-04-23 | Genzyme Corporation | Treatment with kallikrein inhibitors |
| EP2350305A4 (en) | 2008-10-22 | 2013-03-06 | Dyax Corp | COMBINATION TREATMENTS WITH PROTEASE BINDING PROTEINS FOR INFLAMMATORY DISEASES |
-
2007
- 2007-03-13 ES ES07005182.6T patent/ES2601554T3/es active Active
- 2007-03-13 PT PT111522041T patent/PT2374472T/pt unknown
- 2007-03-13 WO PCT/EP2007/002216 patent/WO2007104541A2/en not_active Ceased
- 2007-03-13 HU HUE07005182A patent/HUE031701T2/en unknown
- 2007-03-13 LT LTEP11152204.1T patent/LT2374472T/lt unknown
- 2007-03-13 HU HUE11152204A patent/HUE039108T2/hu unknown
- 2007-03-13 JP JP2008558710A patent/JP5337493B2/ja active Active
- 2007-03-13 PL PL07005182T patent/PL1854477T3/pl unknown
- 2007-03-13 PT PT70051826T patent/PT1854477T/pt unknown
- 2007-03-13 AU AU2007224643A patent/AU2007224643B2/en active Active
- 2007-03-13 ES ES11152204.1T patent/ES2682646T3/es active Active
- 2007-03-13 LT LTEP07005182.6T patent/LT1854477T/lt unknown
- 2007-03-13 SI SI200732044T patent/SI2374472T1/sl unknown
- 2007-03-13 DK DK07005182.6T patent/DK1854477T3/en active
- 2007-03-13 CA CA2646285A patent/CA2646285C/en active Active
- 2007-03-15 US US11/724,197 patent/US20070270344A1/en not_active Abandoned
-
2010
- 2010-06-02 US US12/792,393 patent/US9107928B2/en active Active
-
2012
- 2012-08-01 JP JP2012171140A patent/JP2012211194A/ja not_active Withdrawn
-
2015
- 2015-06-19 US US14/744,532 patent/US20150368359A1/en not_active Abandoned
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