JP2009528275A5 - - Google Patents
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- Publication number
- JP2009528275A5 JP2009528275A5 JP2008552537A JP2008552537A JP2009528275A5 JP 2009528275 A5 JP2009528275 A5 JP 2009528275A5 JP 2008552537 A JP2008552537 A JP 2008552537A JP 2008552537 A JP2008552537 A JP 2008552537A JP 2009528275 A5 JP2009528275 A5 JP 2009528275A5
- Authority
- JP
- Japan
- Prior art keywords
- hydrogen
- carbon atoms
- alkyl
- compound
- dihydroxybenzyloxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 125000004432 carbon atom Chemical group C* 0.000 claims 24
- 229910052739 hydrogen Inorganic materials 0.000 claims 24
- 239000001257 hydrogen Substances 0.000 claims 24
- 125000000217 alkyl group Chemical group 0.000 claims 16
- 150000001875 compounds Chemical class 0.000 claims 13
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 12
- 125000003545 alkoxy group Chemical group 0.000 claims 8
- 125000001475 halogen functional group Chemical group 0.000 claims 8
- 150000002431 hydrogen Chemical class 0.000 claims 8
- 125000004356 hydroxy functional group Chemical group O* 0.000 claims 8
- 239000000203 mixture Substances 0.000 claims 8
- -1 perfluoromethoxy Chemical group 0.000 claims 8
- 206010012601 diabetes mellitus Diseases 0.000 claims 7
- 150000003839 salts Chemical class 0.000 claims 7
- 208000031226 Hyperlipidaemia Diseases 0.000 claims 5
- 208000008589 Obesity Diseases 0.000 claims 5
- 235000020824 obesity Nutrition 0.000 claims 5
- 239000008194 pharmaceutical composition Substances 0.000 claims 5
- 201000001320 Atherosclerosis Diseases 0.000 claims 4
- 208000004930 Fatty Liver Diseases 0.000 claims 4
- 206010019708 Hepatic steatosis Diseases 0.000 claims 4
- 208000031773 Insulin resistance syndrome Diseases 0.000 claims 4
- 208000010706 fatty liver disease Diseases 0.000 claims 4
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 4
- 231100000240 steatosis hepatitis Toxicity 0.000 claims 4
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 claims 4
- 206010003210 Arteriosclerosis Diseases 0.000 claims 3
- 206010006895 Cachexia Diseases 0.000 claims 3
- 208000011775 arteriosclerosis disease Diseases 0.000 claims 3
- 201000010065 polycystic ovary syndrome Diseases 0.000 claims 3
- 208000002177 Cataract Diseases 0.000 claims 2
- 208000003790 Foot Ulcer Diseases 0.000 claims 2
- 206010020772 Hypertension Diseases 0.000 claims 2
- 208000017442 Retinal disease Diseases 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 208000017169 kidney disease Diseases 0.000 claims 2
- 201000001119 neuropathy Diseases 0.000 claims 2
- 230000007823 neuropathy Effects 0.000 claims 2
- 208000033808 peripheral neuropathy Diseases 0.000 claims 2
- 208000001072 type 2 diabetes mellitus Diseases 0.000 claims 2
- 206010067584 Type 1 diabetes mellitus Diseases 0.000 claims 1
- 239000013543 active substance Substances 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000006186 oral dosage form Substances 0.000 claims 1
- 208000024891 symptom Diseases 0.000 claims 1
- 0 **c1ccccc1 Chemical compound **c1ccccc1 0.000 description 1
- RDOXTESZEPMUJZ-UHFFFAOYSA-N COc1ccccc1 Chemical compound COc1ccccc1 RDOXTESZEPMUJZ-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US76206806P | 2006-01-25 | 2006-01-25 | |
| PCT/US2007/060833 WO2007087506A2 (en) | 2006-01-25 | 2007-01-22 | Compounds for the treatment of metabolic disorders |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009528275A JP2009528275A (ja) | 2009-08-06 |
| JP2009528275A5 true JP2009528275A5 (enExample) | 2011-01-20 |
Family
ID=38309906
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008552537A Withdrawn JP2009528275A (ja) | 2006-01-25 | 2007-01-22 | 代謝障害を処置するための化合物 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US7947735B2 (enExample) |
| EP (1) | EP1976378A4 (enExample) |
| JP (1) | JP2009528275A (enExample) |
| KR (1) | KR20080086523A (enExample) |
| CN (1) | CN101374415A (enExample) |
| AU (1) | AU2007208127A1 (enExample) |
| CA (1) | CA2636290A1 (enExample) |
| IL (1) | IL192852A (enExample) |
| NZ (1) | NZ569729A (enExample) |
| WO (1) | WO2007087506A2 (enExample) |
| ZA (1) | ZA200805645B (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1601251B1 (en) * | 2003-02-13 | 2014-11-12 | Wellstat Therapeutics Corporation | Compounds for the treatment of metabolic disorders |
| DK1633340T3 (da) * | 2003-04-15 | 2011-02-07 | Wellstat Therapeutics Corp | Forbindelser til behandling af stofskifteforstyrrelser |
| US7442796B2 (en) * | 2003-04-30 | 2008-10-28 | Wellstat Therapeutics Corporation | Compounds for the treatment of metabolic disorders |
| US20090176885A1 (en) * | 2006-02-02 | 2009-07-09 | Wellstat Therapeutics Corporation | Compounds for the treatment of metabolic disorders |
| WO2007117791A2 (en) | 2006-03-31 | 2007-10-18 | Wellstat Therapeutics Corporation | Combination treatment of metabolic disorders |
| JP2009537559A (ja) * | 2006-05-18 | 2009-10-29 | ウェルスタット セラピューティクス コーポレイション | 代謝障害の処置のための化合物 |
| EP2026659A4 (en) * | 2006-06-09 | 2010-06-30 | Wellstat Therapeutics Corp | COMPOUNDS FOR THE TREATMENT OF METABOLISM DISORDER |
| AU2007285827A1 (en) * | 2006-08-17 | 2008-02-21 | Wellstat Therapeutics Corporation | Combination treatment for metabolic disorders |
| DE102007058842A1 (de) * | 2007-12-05 | 2009-06-10 | Grünenthal GmbH | Arzneimittel |
| EP2240024A4 (en) * | 2008-01-15 | 2014-05-21 | Wellstat Therapeutics Corp | COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS |
| MX2010009959A (es) | 2008-03-13 | 2010-10-04 | Wellstat Therapeutics Corp | Compuestos y metodo para reducir el acido urico. |
| US20130331452A1 (en) | 2010-09-08 | 2013-12-12 | Wellstat Therapeutics Corporation | Benzoic acid compounds for reducing uric acid |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE667498A (enExample) | 1964-07-28 | 1965-11-16 | ||
| US4080335A (en) | 1975-07-28 | 1978-03-21 | Beecham Group Limited | Anorexic chromans |
| FR2653119B1 (fr) | 1989-10-18 | 1994-08-05 | Lipha | Nouveaux aryloxy alcoyl benzenes, leurs procedes de preparation et les compositions pharmaceutiques en renfermant. |
| KR100965201B1 (ko) | 2001-06-12 | 2010-06-24 | 웰스테트 테라퓨틱스 코포레이션 | 대사 질환의 치료용 화합물 |
| US7645772B2 (en) | 2002-11-01 | 2010-01-12 | Wellstat Therapeutics Corporation | Treatment of metabolic disorders |
| EP1601251B1 (en) | 2003-02-13 | 2014-11-12 | Wellstat Therapeutics Corporation | Compounds for the treatment of metabolic disorders |
| DK1633340T3 (da) | 2003-04-15 | 2011-02-07 | Wellstat Therapeutics Corp | Forbindelser til behandling af stofskifteforstyrrelser |
| CN1777576A (zh) | 2003-04-22 | 2006-05-24 | 维尔斯达医疗公司 | 用于治疗代谢紊乱的化合物 |
| US7442796B2 (en) | 2003-04-30 | 2008-10-28 | Wellstat Therapeutics Corporation | Compounds for the treatment of metabolic disorders |
| CA2533890A1 (en) | 2003-08-20 | 2005-03-03 | Wellstat Therapeutics Corporation | Compounds for the treatment of metabolic disorders |
| EP1688138A4 (en) * | 2003-11-26 | 2008-01-16 | Takeda Pharmaceutical | AGENT FOR REGULATING THE FUNCTION OF A RECEIVER |
-
2007
- 2007-01-22 AU AU2007208127A patent/AU2007208127A1/en not_active Abandoned
- 2007-01-22 US US12/160,858 patent/US7947735B2/en not_active Expired - Fee Related
- 2007-01-22 JP JP2008552537A patent/JP2009528275A/ja not_active Withdrawn
- 2007-01-22 KR KR1020087018398A patent/KR20080086523A/ko not_active Ceased
- 2007-01-22 CA CA002636290A patent/CA2636290A1/en not_active Abandoned
- 2007-01-22 NZ NZ569729A patent/NZ569729A/en not_active IP Right Cessation
- 2007-01-22 EP EP07717341A patent/EP1976378A4/en not_active Withdrawn
- 2007-01-22 WO PCT/US2007/060833 patent/WO2007087506A2/en not_active Ceased
- 2007-01-22 CN CNA2007800035511A patent/CN101374415A/zh active Pending
-
2008
- 2008-06-27 ZA ZA200805645A patent/ZA200805645B/xx unknown
- 2008-07-16 IL IL192852A patent/IL192852A/en not_active IP Right Cessation
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