JP2009528030A - 1型糖尿病の診断、予防及び治療において用いられる転写因子Arntl2遺伝子及びその発現産物 - Google Patents

1型糖尿病の診断、予防及び治療において用いられる転写因子Arntl2遺伝子及びその発現産物 Download PDF

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JP2009528030A
JP2009528030A JP2008555900A JP2008555900A JP2009528030A JP 2009528030 A JP2009528030 A JP 2009528030A JP 2008555900 A JP2008555900 A JP 2008555900A JP 2008555900 A JP2008555900 A JP 2008555900A JP 2009528030 A JP2009528030 A JP 2009528030A
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diabetes
arntl2
gene
seq
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JP2009528030A5 (enExample
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アヴナー,フィリップ
ログナー,ユテ,クリスティーヌ
フン,ミン−シウ
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Institut Pasteur
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    • G—PHYSICS
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    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
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    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00—Animals characterised by species
    • A01K2227/10—Mammal
    • A01K2227/105—Murine
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/03—Animal model, e.g. for test or diseases
    • A01K2267/035—Animal model for multifactorial diseases
    • A01K2267/0362—Animal model for lipid/glucose metabolism, e.g. obesity, type-2 diabetes
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/112—Disease subtyping, staging or classification
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
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    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/172—Haplotypes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/04—Endocrine or metabolic disorders
    • G01N2800/042—Disorders of carbohydrate metabolism, e.g. diabetes, glucose metabolism

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  • Health & Medical Sciences (AREA)
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  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Animal Husbandry (AREA)
  • Biophysics (AREA)
  • Biodiversity & Conservation Biology (AREA)
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JP2008555900A 2006-02-27 2007-02-27 1型糖尿病の診断、予防及び治療において用いられる転写因子Arntl2遺伝子及びその発現産物 Withdrawn JP2009528030A (ja)

Applications Claiming Priority (2)

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US77666206P 2006-02-27 2006-02-27
PCT/IB2007/001649 WO2007099461A2 (en) 2006-02-27 2007-02-27 Transcription factor arntl2 gene and expression products thereof used in the diagnosis, prevention, and treatment of type 1 diabetes

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JP2009528030A true JP2009528030A (ja) 2009-08-06
JP2009528030A5 JP2009528030A5 (enExample) 2010-04-02

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JP2008555900A Withdrawn JP2009528030A (ja) 2006-02-27 2007-02-27 1型糖尿病の診断、予防及び治療において用いられる転写因子Arntl2遺伝子及びその発現産物

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US (2) US20090181915A1 (enExample)
EP (1) EP1994174B1 (enExample)
JP (1) JP2009528030A (enExample)
AT (1) ATE485399T1 (enExample)
CA (1) CA2638825A1 (enExample)
DE (1) DE602007009944D1 (enExample)
WO (1) WO2007099461A2 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE602007009944D1 (de) 2006-02-27 2010-12-02 Pasteur Institut Gen des transkriptionsfaktors arntl2 sowie bei der diagnose, vorbeugung und behandlung von typ-1-diabetes verwendete expressionsprodukte davon
CN109295210A (zh) * 2018-10-30 2019-02-01 深圳市万众基因转化医学研究院 一种人类2型糖尿病相关基因突变筛查的组合引物及应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3769465B2 (ja) * 2001-02-13 2006-04-26 独立行政法人科学技術振興機構 新規時計遺伝子Bmal2
WO2006019824A2 (en) * 2004-07-15 2006-02-23 Joslin Diabetes Center, Inc. Methods of treating diabetes
DE602007009944D1 (de) 2006-02-27 2010-12-02 Pasteur Institut Gen des transkriptionsfaktors arntl2 sowie bei der diagnose, vorbeugung und behandlung von typ-1-diabetes verwendete expressionsprodukte davon

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DE602007009944D1 (de) 2010-12-02
US20090181915A1 (en) 2009-07-16
CA2638825A1 (en) 2007-09-07
US20070214510A1 (en) 2007-09-13
EP1994174A2 (en) 2008-11-26
EP1994174B1 (en) 2010-10-20
ATE485399T1 (de) 2010-11-15
WO2007099461A2 (en) 2007-09-07
US7960107B2 (en) 2011-06-14
WO2007099461A3 (en) 2007-12-27
HK1126251A1 (en) 2009-08-28

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