JP2009527467A5 - - Google Patents

Info

Publication number

JP2009527467A5

JP2009527467A5 JP2008553814A JP2008553814A JP2009527467A5 JP 2009527467 A5 JP2009527467 A5 JP 2009527467A5 JP 2008553814 A JP2008553814 A JP 2008553814A JP 2008553814 A JP2008553814 A JP 2008553814A JP 2009527467 A5 JP2009527467 A5 JP 2009527467A5

Authority

JP

Japan

Prior art keywords

compound according

optionally substituted

independently

group

alkyl

Prior art date

2007-01-23

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Withdrawn

Links

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• 150000001875 compounds Chemical class 0.000 claims 9
• -1 carboxy, carboxy ester Chemical class 0.000 claims 5
• 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 4
• 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims 3
• 125000000623 heterocyclic group Chemical group 0.000 claims 3
• 229910052739 hydrogen Inorganic materials 0.000 claims 3
• 239000001257 hydrogen Substances 0.000 claims 3
• UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 2
• 150000001413 amino acids Chemical class 0.000 claims 2
• 125000004432 carbon atom Chemical group C* 0.000 claims 2
• 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 2
• 125000006413 ring segment Chemical group 0.000 claims 2
• 125000004169 (C1-C6) alkyl group Chemical group 0.000 claims 1
• 125000006656 (C2-C4) alkenyl group Chemical group 0.000 claims 1
• 125000006650 (C2-C4) alkynyl group Chemical group 0.000 claims 1
• 125000000882 C2-C6 alkenyl group Chemical group 0.000 claims 1
• 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 claims 1
• 125000002837 carbocyclic group Chemical group 0.000 claims 1
• 229910052799 carbon Inorganic materials 0.000 claims 1
• 125000005392 carboxamide group Chemical group NC(=O)* 0.000 claims 1
• 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims 1
• 230000005494 condensation Effects 0.000 claims 1
• 238000009833 condensation Methods 0.000 claims 1
• 125000000753 cycloalkyl group Chemical group 0.000 claims 1
• 125000001995 cyclobutyl group Chemical group [H]C1([H])C([H])([H])C([H])(*)C1([H])[H] 0.000 claims 1
• 125000004850 cyclobutylmethyl group Chemical group C1(CCC1)C* 0.000 claims 1
• 125000000113 cyclohexyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C([H])([H])C1([H])[H] 0.000 claims 1
• 125000004210 cyclohexylmethyl group Chemical group [H]C([H])(*)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H] 0.000 claims 1
• 125000001511 cyclopentyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C1([H])[H] 0.000 claims 1
• 125000004851 cyclopentylmethyl group Chemical group C1(CCCC1)C* 0.000 claims 1
• 125000004186 cyclopropylmethyl group Chemical group [H]C([H])(*)C1([H])C([H])([H])C1([H])[H] 0.000 claims 1
• 239000003937 drug carrier Substances 0.000 claims 1
• 125000004185 ester group Chemical group 0.000 claims 1
• 229910052736 halogen Inorganic materials 0.000 claims 1
• 150000002367 halogens Chemical class 0.000 claims 1
• 150000002431 hydrogen Chemical class 0.000 claims 1
• 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 claims 1
• 125000002757 morpholinyl group Chemical group 0.000 claims 1
• 125000004123 n-propyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])* 0.000 claims 1
• 125000004043 oxo group Chemical group O=* 0.000 claims 1
• 239000008194 pharmaceutical composition Substances 0.000 claims 1
• 125000004193 piperazinyl group Chemical group 0.000 claims 1
• 125000003386 piperidinyl group Chemical group 0.000 claims 1
• 125000004076 pyridyl group Chemical group 0.000 claims 1
• 125000005344 pyridylmethyl group Chemical group [H]C1=C([H])C([H])=C([H])C(=N1)C([H])([H])* 0.000 claims 1
• 150000003839 salts Chemical class 0.000 claims 1
• 239000012453 solvate Substances 0.000 claims 1
• 125000001424 substituent group Chemical group 0.000 claims 1
• 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 claims 1