JP2009525286A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2009525286A5 JP2009525286A5 JP2008552621A JP2008552621A JP2009525286A5 JP 2009525286 A5 JP2009525286 A5 JP 2009525286A5 JP 2008552621 A JP2008552621 A JP 2008552621A JP 2008552621 A JP2008552621 A JP 2008552621A JP 2009525286 A5 JP2009525286 A5 JP 2009525286A5
- Authority
- JP
- Japan
- Prior art keywords
- immunoglobulin
- igm
- resin
- supernatant
- precipitate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 108060003951 Immunoglobulin Proteins 0.000 claims 9
- 102000018358 immunoglobulin Human genes 0.000 claims 9
- 239000011347 resin Substances 0.000 claims 6
- 229920005989 resin Polymers 0.000 claims 6
- 239000006228 supernatant Substances 0.000 claims 6
- WWZKQHOCKIZLMA-UHFFFAOYSA-N octanoic acid Chemical compound CCCCCCCC(O)=O WWZKQHOCKIZLMA-UHFFFAOYSA-N 0.000 claims 4
- 239000002244 precipitate Substances 0.000 claims 4
- 239000003957 anion exchange resin Substances 0.000 claims 3
- 229940027941 immunoglobulin g Drugs 0.000 claims 3
- 239000008194 pharmaceutical composition Substances 0.000 claims 3
- 239000000243 solution Substances 0.000 claims 3
- 239000007858 starting material Substances 0.000 claims 3
- 239000000126 substance Substances 0.000 claims 3
- 239000005635 Caprylic acid (CAS 124-07-2) Substances 0.000 claims 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims 2
- 239000010836 blood and blood product Substances 0.000 claims 2
- 229940125691 blood product Drugs 0.000 claims 2
- 229960002446 octanoic acid Drugs 0.000 claims 2
- 239000000427 antigen Substances 0.000 claims 1
- 102000036639 antigens Human genes 0.000 claims 1
- 108091007433 antigens Proteins 0.000 claims 1
- 239000007853 buffer solution Substances 0.000 claims 1
- 238000002523 gelfiltration Methods 0.000 claims 1
- 229940099472 immunoglobulin a Drugs 0.000 claims 1
- 229940072221 immunoglobulins Drugs 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 239000011780 sodium chloride Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US76342206P | 2006-01-30 | 2006-01-30 | |
| US60/763,422 | 2006-01-30 | ||
| PCT/US2007/061269 WO2007106617A2 (en) | 2006-01-30 | 2007-01-30 | Method of treatment and prophylaxis of diseases related to amyloid deposition using igm |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013179382A Division JP2013256529A (ja) | 2006-01-30 | 2013-08-30 | ＩｇＭを使用する治療方法および予防方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009525286A JP2009525286A (ja) | 2009-07-09 |
| JP2009525286A5 true JP2009525286A5 (https=) | 2010-03-18 |
| JP5697847B2 JP5697847B2 (ja) | 2015-04-08 |
Family
ID=38510126
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008552621A Active JP5697847B2 (ja) | 2006-01-30 | 2007-01-30 | ＩｇＭを使用する治療方法および予防方法 |
| JP2013179382A Pending JP2013256529A (ja) | 2006-01-30 | 2013-08-30 | ＩｇＭを使用する治療方法および予防方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013179382A Pending JP2013256529A (ja) | 2006-01-30 | 2013-08-30 | ＩｇＭを使用する治療方法および予防方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US8852585B2 (https=) |
| EP (1) | EP1981540B1 (https=) |
| JP (2) | JP5697847B2 (https=) |
| ES (1) | ES2409844T3 (https=) |
| PL (1) | PL1981540T3 (https=) |
| PT (1) | PT1981540E (https=) |
| WO (1) | WO2007106617A2 (https=) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10303974A1 (de) | 2003-01-31 | 2004-08-05 | Abbott Gmbh & Co. Kg | Amyloid-β(1-42)-Oligomere, Verfahren zu deren Herstellung und deren Verwendung |
| US8691224B2 (en) | 2005-11-30 | 2014-04-08 | Abbvie Inc. | Anti-Aβ globulomer 5F7 antibodies |
| HRP20140240T4 (hr) | 2005-11-30 | 2017-02-24 | Abbvie Inc. | Monoklonalna antitijela protiv amiloidnih beta proteina i njihova upotreba |
| US8455626B2 (en) | 2006-11-30 | 2013-06-04 | Abbott Laboratories | Aβ conformer selective anti-aβ globulomer monoclonal antibodies |
| US8895004B2 (en) | 2007-02-27 | 2014-11-25 | AbbVie Deutschland GmbH & Co. KG | Method for the treatment of amyloidoses |
| US8048420B2 (en) | 2007-06-12 | 2011-11-01 | Ac Immune S.A. | Monoclonal antibody |
| US8613923B2 (en) | 2007-06-12 | 2013-12-24 | Ac Immune S.A. | Monoclonal antibody |
| AU2008311367B2 (en) | 2007-10-05 | 2014-11-13 | Ac Immune S.A. | Use of anti-amyloid beta antibody in ocular diseases |
| US8987419B2 (en) | 2010-04-15 | 2015-03-24 | AbbVie Deutschland GmbH & Co. KG | Amyloid-beta binding proteins |
| EP2598882B1 (en) | 2010-07-30 | 2017-07-26 | AC Immune S.A. | Safe and functional humanized antibodies for use in treating an amyloidosis |
| EP3533803B1 (en) | 2010-08-14 | 2021-10-27 | AbbVie Inc. | Anti-amyloid-beta antibodies |
| SI2961426T1 (sl) | 2013-02-26 | 2020-01-31 | Baxalta GmbH | Zdravljanje motenj centralnega živčnega sistema z intranazalnim dajanjem imunoglobulina G |
| HUE044737T2 (hu) * | 2013-05-06 | 2019-11-28 | Baxalta Inc | Alzheimer-kór szubpopulációk kezelése egyesített immunglubulin G-vel |
| US9107906B1 (en) | 2014-10-28 | 2015-08-18 | Adma Biologics, Inc. | Compositions and methods for the treatment of immunodeficiency |
| US10259865B2 (en) | 2017-03-15 | 2019-04-16 | Adma Biologics, Inc. | Anti-pneumococcal hyperimmune globulin for the treatment and prevention of pneumococcal infection |
| UY39318A (es) * | 2020-07-10 | 2022-02-25 | Grifols Worldwide Operations Ltd | Procedimiento para obtener una composicion que comprende inmunoglobulina m derivada de plasma humano |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3927112C1 (https=) * | 1989-08-17 | 1990-10-25 | Biotest Pharma Gmbh, 6072 Dreieich, De | |
| US5554601A (en) * | 1993-11-05 | 1996-09-10 | University Of Florida | Methods for neuroprotection |
| US5877399A (en) * | 1994-01-27 | 1999-03-02 | Johns Hopkins University | Transgenic mice expressing APP-Swedish mutation develop progressive neurologic disease |
| US7473423B2 (en) * | 1994-04-29 | 2009-01-06 | Mayo Foundation For Medical Education And Research | Human IgM antibodies, and diagnostic and therapeutic uses thereof particularly in the central nervous system |
| US5986054A (en) | 1995-04-28 | 1999-11-16 | The Hospital For Sick Children, Hsc Research And Development Limited Partnership | Genetic sequences and proteins related to alzheimer's disease |
| JP2000506375A (ja) | 1996-01-26 | 2000-05-30 | エイチエスシー リサーチ アンド デベロップメント リミテッド パートナーシップ | アルツハイマー病に関連する核酸およびタンパク質、ならびにその使用 |
| EP0835880A1 (de) * | 1996-10-14 | 1998-04-15 | Rotkreuzstiftung Zentrallaboratorium Blutspendedienst Srk | Verfahren zur Herstellung eines IgM Präparates für die intravenöse Applikation |
| US5886154A (en) * | 1997-06-20 | 1999-03-23 | Lebing; Wytold R. | Chromatographic method for high yield purification and viral inactivation of antibodies |
| EP1172378A1 (en) | 2000-07-12 | 2002-01-16 | Richard Dr. Dodel | Human beta-amyloid antibody and use thereof for treatment of alzheimer's disease |
| FR2824568B1 (fr) * | 2001-05-11 | 2004-04-09 | Lab Francais Du Fractionnement | Procede de preparation de concentres d'immunoglobulines humaines a usage therapeutique |
| AU2003230391A1 (en) * | 2002-05-15 | 2003-12-02 | Hazel P. Drew | METHOD OF TREATING IMMUNE-MEDIATED DISEASES BY ADMINISTRATION OF IgM |
| DE602004030451D1 (de) * | 2003-07-15 | 2011-01-20 | Chugai Pharmaceutical Co Ltd | Produktion von igm durch transformierte zellen und verfahren zur quantifizierung dieser igm-produktion |
-
2007
- 2007-01-30 US US12/162,532 patent/US8852585B2/en active Active
- 2007-01-30 ES ES07756509T patent/ES2409844T3/es active Active
- 2007-01-30 PL PL07756509T patent/PL1981540T3/pl unknown
- 2007-01-30 JP JP2008552621A patent/JP5697847B2/ja active Active
- 2007-01-30 WO PCT/US2007/061269 patent/WO2007106617A2/en not_active Ceased
- 2007-01-30 PT PT77565091T patent/PT1981540E/pt unknown
- 2007-01-30 EP EP07756509A patent/EP1981540B1/en active Active
-
2013
- 2013-08-30 JP JP2013179382A patent/JP2013256529A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2009525286A5 (https=) | ||
| JP4776615B2 (ja) | 抗体精製 | |
| US10053489B2 (en) | Method for purifying antibody | |
| JP6463734B2 (ja) | 抗体を精製するための連続的多工程法 | |
| JP6843438B2 (ja) | 改変κ軽鎖結合ポリペプチド | |
| Sheth et al. | Affinity precipitation of a monoclonal antibody from an industrial harvest feedstock using an ELP‐Z stimuli responsive biopolymer | |
| EP0143413B1 (de) | Digitalis-Antikörper, Verfahren zu ihrer Herstellung und ihre Verwendung zur Therapie von Digitalis-Intoxikationen | |
| ES2449148T3 (es) | Purificación de inmunoglobulinas | |
| JP2016519137A5 (https=) | ||
| Hage et al. | Affinity chromatography: a historical perspective | |
| JP2019034963A (ja) | 陽イオン交換基を用いた新規抗体精製法（Ｎｏｖｅｌ Ａｎｔｉｂｏｄｙ Ｐｕｒｉｆｉｃａｔｉｏｎ ｍｅｔｈｏｄ ｕｓｉｎｇ Ｃａｔｉｏｎ Ｅｘｃｈａｎｇｅｒ） | |
| JP2016530533A5 (https=) | ||
| JP2007532477A5 (https=) | ||
| Holstein et al. | Mobile phase modifier effects in multimodal cation exchange chromatography | |
| JP6335785B2 (ja) | ミックスモード抗体アフィニティー分離マトリックスとそれを用いた精製方法および標的分子 | |
| KR20190141795A (ko) | 단백질 a 기반 친화성 크로마토그래피 컬럼의 세정 방법 | |
| JP2011521653A5 (https=) | ||
| CN104507954A (zh) | 磨光白蛋白的方法 | |
| Zhang et al. | Purification of monoclonal antibodies by chemical affinity mixed mode chromatography | |
| Capela et al. | Monoclonal Antibodies Addressing the Challenges on the Manufacturing Processing of an Advanced Class of Therapeutic Agents | |
| Rajak et al. | Purification of monoclonal antibodies, IgG1, from cell culture supernatant by use of metal chelate convective interaction media monolithic columns | |
| JPH0132839B2 (https=) | ||
| DE2718325C2 (de) | Leucinreiches 3,1-S-α↓2↓-Glykoprotein sowie dessen Verwendung | |
| Chai et al. | Improved purification of immunoglobulin G from plasma by mixed‐mode chromatography | |
| McCann et al. | Purification of transferrin from Cohn supernatant I using ion‐exchange chromatography |