JP2009524684A - 眼疾患および障害の治療のための組成物および方法 - Google Patents

眼疾患および障害の治療のための組成物および方法 Download PDF

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Publication number
JP2009524684A
JP2009524684A JP2008552479A JP2008552479A JP2009524684A JP 2009524684 A JP2009524684 A JP 2009524684A JP 2008552479 A JP2008552479 A JP 2008552479A JP 2008552479 A JP2008552479 A JP 2008552479A JP 2009524684 A JP2009524684 A JP 2009524684A
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JP
Japan
Prior art keywords
retinal
saturated
lower alkyl
cycloalkyl
retinylamine
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Pending
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JP2008552479A
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Japanese (ja)
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JP2009524684A5 (enExample
Inventor
良 窪田
アーマド ファウジ,
イアン レスリー スコット,
ウラジミール エー. ククサ,
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アキュセラ, インコーポレイテッド
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Publication of JP2009524684A publication Critical patent/JP2009524684A/ja
Publication of JP2009524684A5 publication Critical patent/JP2009524684A5/ja
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents

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  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2008552479A 2006-01-26 2007-01-26 眼疾患および障害の治療のための組成物および方法 Pending JP2009524684A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US76238406P 2006-01-26 2006-01-26
PCT/US2007/002330 WO2007089673A2 (en) 2006-01-26 2007-01-26 Compositions and methods for treatment of ophthalmic diseases and disorders

Publications (2)

Publication Number Publication Date
JP2009524684A true JP2009524684A (ja) 2009-07-02
JP2009524684A5 JP2009524684A5 (enExample) 2010-03-25

Family

ID=38327945

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008552479A Pending JP2009524684A (ja) 2006-01-26 2007-01-26 眼疾患および障害の治療のための組成物および方法

Country Status (5)

Country Link
US (1) US20090197967A1 (enExample)
EP (1) EP1988889A4 (enExample)
JP (1) JP2009524684A (enExample)
CA (1) CA2640151A1 (enExample)
WO (1) WO2007089673A2 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2009011360A (es) 2007-04-20 2010-02-12 Acucela Inc Compuestos derivados de estirenilo para tratar enfermedades y trastornos oftalmicos.
CA2690229C (en) 2007-06-29 2013-10-29 Acucela, Inc. Alkynyl phenyl derivative compounds for treating ophthalmic diseases and disorders
US8821870B2 (en) * 2008-07-18 2014-09-02 Allergan, Inc. Method for treating atrophic age related macular degeneration
BRPI0919327A2 (pt) * 2008-09-05 2019-09-24 Acucela Inc compostos ligados a enxofre para tratar doenças e distúrbios oftálmicos
US10117868B2 (en) 2011-10-25 2018-11-06 Case Western Reserve University Systems pharmacology for treating ocular disorders
US10471118B2 (en) * 2014-05-30 2019-11-12 Case Western Reserve University Retinylamine derivitives for treatment of ocular disorders
EP3151818A4 (en) * 2014-06-04 2018-05-30 Case Western Reserve University Compositions and methods of treating diabetic retinopathy
US10363231B2 (en) 2014-11-24 2019-07-30 Case Western Reserve University Compounds and methods of treating ocular disorders

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6437003B1 (en) * 1997-10-31 2002-08-20 Jean-Baptiste Roullet Use of retinoids to treat high blood pressure and other cardiovascular disease
WO2006091761A1 (en) * 2005-02-24 2006-08-31 University Of Washington Methods for treatment of retinal degenerative disease

Also Published As

Publication number Publication date
EP1988889A4 (en) 2009-07-22
EP1988889A2 (en) 2008-11-12
WO2007089673A2 (en) 2007-08-09
WO2007089673A3 (en) 2008-02-28
CA2640151A1 (en) 2007-08-09
US20090197967A1 (en) 2009-08-06
WO2007089673A8 (en) 2008-04-10

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