BRPI0919327A2 - compostos ligados a enxofre para tratar doenças e distúrbios oftálmicos - Google Patents
compostos ligados a enxofre para tratar doenças e distúrbios oftálmicosInfo
- Publication number
- BRPI0919327A2 BRPI0919327A2 BRPI0919327A BRPI0919327A BRPI0919327A2 BR PI0919327 A2 BRPI0919327 A2 BR PI0919327A2 BR PI0919327 A BRPI0919327 A BR PI0919327A BR PI0919327 A BRPI0919327 A BR PI0919327A BR PI0919327 A2 BRPI0919327 A2 BR PI0919327A2
- Authority
- BR
- Brazil
- Prior art keywords
- disorders
- sulfur
- ophthalmic diseases
- linked compounds
- treat ophthalmic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C321/00—Thiols, sulfides, hydropolysulfides or polysulfides
- C07C321/24—Thiols, sulfides, hydropolysulfides, or polysulfides having thio groups bound to carbon atoms of six-membered aromatic rings
- C07C321/28—Sulfides, hydropolysulfides, or polysulfides having thio groups bound to carbon atoms of six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C323/31—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
- C07C323/32—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton having at least one of the nitrogen atoms bound to an acyclic carbon atom of the carbon skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/095—Sulfur, selenium, or tellurium compounds, e.g. thiols
- A61K31/10—Sulfides; Sulfoxides; Sulfones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/145—Amines having sulfur, e.g. thiurams (>N—C(S)—S—C(S)—N< and >N—C(S)—S—S—C(S)—N<), Sulfinylamines (—N=SO), Sulfonylamines (—N=SO2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/30—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/37—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/16—Sulfones; Sulfoxides having sulfone or sulfoxide groups and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C317/22—Sulfones; Sulfoxides having sulfone or sulfoxide groups and singly-bound oxygen atoms bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/26—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C317/32—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/26—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C317/32—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
- C07C317/34—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having sulfone or sulfoxide groups and amino groups bound to carbon atoms of six-membered aromatic rings being part of the same non-condensed ring or of a condensed ring system containing that ring
- C07C317/36—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having sulfone or sulfoxide groups and amino groups bound to carbon atoms of six-membered aromatic rings being part of the same non-condensed ring or of a condensed ring system containing that ring with the nitrogen atoms of the amino groups bound to hydrogen atoms or to carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/10—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C323/18—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
- C07C323/20—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton with singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C323/39—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
- C07C323/40—Y being a hydrogen or a carbon atom
- C07C323/41—Y being a hydrogen or an acyclic carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/62—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/05—Isotopically modified compounds, e.g. labelled
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/18—Systems containing only non-condensed rings with a ring being at least seven-membered
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Ophthalmology & Optometry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US9484108P | 2008-09-05 | 2008-09-05 | |
US19706508P | 2008-10-22 | 2008-10-22 | |
PCT/US2009/055785 WO2010028088A2 (en) | 2008-09-05 | 2009-09-02 | Sulfur-linked compounds for treating opthalmic diseases and disorders |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0919327A2 true BRPI0919327A2 (pt) | 2019-09-24 |
Family
ID=41203024
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0919327A BRPI0919327A2 (pt) | 2008-09-05 | 2009-09-02 | compostos ligados a enxofre para tratar doenças e distúrbios oftálmicos |
Country Status (19)
Country | Link |
---|---|
US (1) | US20100093865A1 (pt) |
EP (1) | EP2344451A4 (pt) |
JP (1) | JP5647125B2 (pt) |
KR (1) | KR101395952B1 (pt) |
CN (1) | CN102203058B (pt) |
AU (1) | AU2009288087A1 (pt) |
BR (1) | BRPI0919327A2 (pt) |
CA (1) | CA2736229C (pt) |
CO (1) | CO6361991A2 (pt) |
EA (1) | EA022974B1 (pt) |
EC (1) | ECSP11010956A (pt) |
GB (1) | GB2463151A (pt) |
HK (1) | HK1158616A1 (pt) |
IL (1) | IL211534A (pt) |
MX (1) | MX2011002448A (pt) |
MY (1) | MY153738A (pt) |
NZ (1) | NZ592057A (pt) |
TW (1) | TWI433670B (pt) |
WO (1) | WO2010028088A2 (pt) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW201311149A (zh) * | 2011-06-24 | 2013-03-16 | Ishihara Sangyo Kaisha | 有害生物防治劑 |
WO2013109991A1 (en) | 2012-01-20 | 2013-07-25 | Acucela Inc. | Substituted heterocyclic compounds for disease treatment |
TW201406707A (zh) | 2012-05-04 | 2014-02-16 | Acucela Inc | 用以治療糖尿病性視網膜病變及其他眼部疾病之方法 |
JP6678455B2 (ja) | 2012-12-21 | 2020-04-08 | エピザイム,インコーポレイティド | Prmt5阻害剤およびその使用 |
EP2935241A1 (en) | 2012-12-21 | 2015-10-28 | Epizyme, Inc. | Prmt5 inhibitors and uses thereof |
CA2894157A1 (en) | 2012-12-21 | 2014-06-26 | Epizyme, Inc. | Prmt5 inhibitors and uses thereof |
US9745291B2 (en) | 2012-12-21 | 2017-08-29 | Epizyme, Inc. | PRMT5 inhibitors containing a dihydro- or tetrahydroisoquinoline and uses thereof |
US9908887B2 (en) | 2012-12-21 | 2018-03-06 | Epizyme, Inc. | PRMT5 inhibitors and uses thereof |
CA2953572A1 (en) | 2014-08-04 | 2016-02-11 | Epizyme, Inc. | Prmt5 inhibitors and uses thereof |
TWI640308B (zh) * | 2017-03-29 | 2018-11-11 | 林伯剛 | Device for stimulating optic nerve fibers |
Family Cites Families (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2744136A (en) * | 1953-02-16 | 1956-05-01 | Du Pont | Amides of sulfonylserinophenones |
DE2710997C3 (de) * | 1977-03-14 | 1980-08-14 | Dr. Karl Thomae Gmbh, 7950 Biberach | 4-Alkoxy carbonylamino-phenyläthanolamine, deren Herstellung und deren Verwendung als Arzneimittel |
IL56755A (en) * | 1979-02-27 | 1984-08-31 | Yissum Res Dev Co | Sex stimulant compositions comprising phenethylamine derivatives,certain such compounds and their preparation |
US4412856A (en) * | 1980-05-31 | 1983-11-01 | Ciba-Geigy Corporation | Herbicidal heterocyclic and substituted phenyl phenylacetylene amines |
DE3208189A1 (de) * | 1982-03-06 | 1983-09-08 | Hoechst Ag, 6230 Frankfurt | 2-aminomethyl-6-sulfamoylphenolderivate, verfahren zu ihrer herstellung, ihre verwendung sowie pharmazeutische praeparate auf basis dieser verbindungen |
JPH0228112A (ja) * | 1988-04-21 | 1990-01-30 | Kaken Pharmaceut Co Ltd | 点眼用眼圧調整剤 |
US5523302A (en) * | 1993-11-24 | 1996-06-04 | The Du Pont Merck Pharmaceutical Company | Aromatic compounds containing basic and acidic termini useful as fibrinogen receptor antagonists |
FR2768054A1 (fr) * | 1997-09-11 | 1999-03-12 | Synthelabo | Utilisation de derives de benzene sulfonamide pour obtenir un medicament destine au traitement de l'ejaculation retrograde ou de l'aspermie |
ATE319712T1 (de) * | 1999-12-21 | 2006-03-15 | Mgi Gp Inc | Hydantoin derivate, pharmazeutische zusammensetzungen und verfahren zu ihrer verwendung |
DE10059412A1 (de) * | 2000-11-30 | 2002-06-13 | Gruenenthal Gmbh | Verwendung von 1-Phenyl-3-dimethylamino-propanverbindungen zur Therapie der Harninkontinenz |
US20030032078A1 (en) * | 2001-01-23 | 2003-02-13 | Board Of Regents, The University Of Texas System | Methods and compositions for the treatment of macular and retinal degenerations |
EP1443041A4 (en) * | 2001-11-09 | 2006-06-07 | Kissei Pharmaceutical | 5-AMIDINO-2-HYDROXYBENZENE-SULFONAMIDE DERIVATIVES, MEDICINAL COMPOSITIONS CONTAINING THEM, THEIR MEDICAL USE AND INTERMEDIATE PRODUCTS USED IN THEIR PRODUCTION |
PA8557501A1 (es) * | 2001-11-12 | 2003-06-30 | Pfizer Prod Inc | Benzamida, heteroarilamida y amidas inversas |
TW200301698A (en) * | 2001-12-21 | 2003-07-16 | Bristol Myers Squibb Co | Acridone inhibitors of IMPDH enzyme |
ITRM20020629A1 (it) * | 2002-12-19 | 2004-06-20 | Sigma Tau Ind Farmaceuti | Uso di acidi alfa-feniltiocarbossilici e alfa-fenilossicarbossilici ad attivita' ipoglicemizzante e/o ipolipidemizzante. |
CN100345823C (zh) * | 2003-01-14 | 2007-10-31 | 赛特凯恩蒂克公司 | 化合物、组合物及方法 |
ATE552236T1 (de) * | 2003-01-14 | 2012-04-15 | Cytokinetics Inc | Verbindungen, zusammensetzungen und verfahren zur behandlung von herzinsuffizienz |
US20060281821A1 (en) * | 2003-03-14 | 2006-12-14 | Krzysztof Palczewski | Retinoid replacements and opsin agonists and methods for the use thereof |
US7566808B2 (en) * | 2004-02-17 | 2009-07-28 | President And Fellows Of Harvard College | Management of ophthalmologic disorders, including macular degeneration |
JP2006111553A (ja) | 2004-10-13 | 2006-04-27 | Dainippon Sumitomo Pharma Co Ltd | スルホニルオキシインドール誘導体及びそれを含有する医薬組成物 |
WO2006091796A2 (en) * | 2005-02-22 | 2006-08-31 | Acucela, Inc. | Compositions and methods for diagnosing and treating retinal diseases |
FR2882750B1 (fr) * | 2005-03-03 | 2007-05-11 | Pierre Fabre Medicament Sa | Derives de 1,2,4-triazines, leur preparation et leur application en therapeutique humaine |
TW200744567A (en) * | 2005-09-23 | 2007-12-16 | Alcon Inc | Phenylethylamine analogs and their use for treating glaucoma |
EP1988889A4 (en) * | 2006-01-26 | 2009-07-22 | Acucela Inc | COMPOSITIONS AND METHODS OF TREATMENT FOR OPHTHALMIC DISEASES AND DISORDERS |
EP1889846A1 (en) * | 2006-07-13 | 2008-02-20 | Novartis AG | Purine derivatives as A2a agonists |
EP2144890A1 (en) * | 2007-02-07 | 2010-01-20 | Wyeth | Method for preparing halogenated amines |
AR070950A1 (es) * | 2007-11-01 | 2010-05-19 | Acucela Inc | Compuestos derivados de amina, composiciones farmaceuticas de ellos, compuestos inhibidores de produccion de 11-cis-retinol y metodos para tratar enfermedades y trastornos oftalmicos |
-
2009
- 2009-09-02 NZ NZ592057A patent/NZ592057A/xx not_active IP Right Cessation
- 2009-09-02 US US12/553,054 patent/US20100093865A1/en not_active Abandoned
- 2009-09-02 MX MX2011002448A patent/MX2011002448A/es active IP Right Grant
- 2009-09-02 EA EA201100462A patent/EA022974B1/ru not_active IP Right Cessation
- 2009-09-02 BR BRPI0919327A patent/BRPI0919327A2/pt not_active IP Right Cessation
- 2009-09-02 EP EP09812186.6A patent/EP2344451A4/en not_active Withdrawn
- 2009-09-02 CN CN200980144266.0A patent/CN102203058B/zh not_active Expired - Fee Related
- 2009-09-02 AU AU2009288087A patent/AU2009288087A1/en not_active Abandoned
- 2009-09-02 GB GB0915259A patent/GB2463151A/en not_active Withdrawn
- 2009-09-02 MY MYPI2011001010A patent/MY153738A/en unknown
- 2009-09-02 CA CA2736229A patent/CA2736229C/en not_active Expired - Fee Related
- 2009-09-02 JP JP2011526175A patent/JP5647125B2/ja not_active Expired - Fee Related
- 2009-09-02 KR KR1020117006817A patent/KR101395952B1/ko not_active IP Right Cessation
- 2009-09-02 WO PCT/US2009/055785 patent/WO2010028088A2/en active Application Filing
- 2009-09-03 TW TW098129721A patent/TWI433670B/zh active
-
2011
- 2011-03-03 IL IL211534A patent/IL211534A/en not_active IP Right Cessation
- 2011-04-05 EC EC2011010956A patent/ECSP11010956A/es unknown
- 2011-04-05 CO CO11041809A patent/CO6361991A2/es not_active Application Discontinuation
- 2011-11-23 HK HK11112715.6A patent/HK1158616A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
MX2011002448A (es) | 2011-05-25 |
ECSP11010956A (es) | 2011-05-31 |
CA2736229C (en) | 2015-06-09 |
KR101395952B1 (ko) | 2014-05-21 |
CA2736229A1 (en) | 2010-03-11 |
CN102203058B (zh) | 2014-11-12 |
HK1158616A1 (en) | 2012-07-20 |
EP2344451A4 (en) | 2014-08-13 |
KR20110046565A (ko) | 2011-05-04 |
MY153738A (en) | 2015-03-13 |
NZ592057A (en) | 2013-01-25 |
JP2012502041A (ja) | 2012-01-26 |
GB2463151A (en) | 2010-03-10 |
US20100093865A1 (en) | 2010-04-15 |
EA022974B1 (ru) | 2016-04-29 |
IL211534A0 (en) | 2011-05-31 |
CN102203058A (zh) | 2011-09-28 |
CO6361991A2 (es) | 2012-01-20 |
EA201100462A1 (ru) | 2011-10-31 |
WO2010028088A3 (en) | 2010-06-17 |
JP5647125B2 (ja) | 2014-12-24 |
TWI433670B (zh) | 2014-04-11 |
AU2009288087A1 (en) | 2010-03-11 |
WO2010028088A2 (en) | 2010-03-11 |
EP2344451A2 (en) | 2011-07-20 |
GB0915259D0 (en) | 2009-10-07 |
TW201021789A (en) | 2010-06-16 |
IL211534A (en) | 2015-10-29 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
BRPI0919327A2 (pt) | compostos ligados a enxofre para tratar doenças e distúrbios oftálmicos | |
BRPI0919920A2 (pt) | compostos para tratamento de doenças e desordens oftálmicas | |
BRPI0812755A2 (pt) | Compostos de derivados de fenil alquinila para tratar doenças, e desordens oftálmicas | |
BRPI0914614A2 (pt) | 2-arilaminoquinazolinas para tratar doenças proliferativas | |
BRPI0911426A2 (pt) | ferramentas terapêuticas e métodos para tratar cegueira | |
BRPI0915476A2 (pt) | dispositivo para tratar problemas respiratórios | |
BRPI0819241A2 (pt) | Compostos derivados de amina para o tratamento de distúrbios e doenças oftálmicas | |
BRPI0906746A2 (pt) | Aparelho para tratamento de doença de refluxo gastresofágico | |
BRPI0810082A2 (pt) | 3-imidazolil-indóis para o tratamento de doenças proliferativas | |
DK2877184T3 (da) | Sammensætninger og behandling for øjensygdomme og -lidelser | |
DK2701697T3 (da) | Oxidative nethindesygdomme | |
BR112012001817A2 (pt) | furazanobenzimidazóis como profármacos para tratar doenças neoplásicas ou autoimunes | |
IL201285A0 (en) | Styrenyl derivative compounds for treating ophthalmic diseases and disorders | |
BR112012011730A2 (pt) | tratamentos para distúrbios gastrointestinais | |
BRPI0919004A2 (pt) | composto de multiheteroarila como inibidores de h-pgds e sua utilização para o tratamento de doenças mediadas por prostaglandina d2 | |
BRPI0810091A2 (pt) | Agentes fugicidas tópicos para tratar distúrbios ungueais | |
BRPI1011226A2 (pt) | métodos para tratar condições relacionadas ao cabelo | |
BR112012004836A2 (pt) | pirazinilpiridinas úteis para o tratamento de doenças proliferativas | |
BRPI0917440A2 (pt) | composições farmacêuticas oftálmicas para o tratamento de patologias neoangiogênicas do olho | |
BR112014013694A2 (pt) | método para tratar uma doença, e, kit | |
BRPI0822264A2 (pt) | Dapsona para tratar rosácea | |
BR112013022424A2 (pt) | órteses para tornozelo e pé | |
BRPI1013903A2 (pt) | tratamentos terapêuticos utilizando centaquina | |
BRPI0908014A2 (pt) | método para tratar cabelo | |
BR112013013636A2 (pt) | processos para o tratamento de doenças da retina |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] | ||
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2543 DE 01-10-2019 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |