JP2009524008A5 - - Google Patents
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- JP2009524008A5 JP2009524008A5 JP2008543520A JP2008543520A JP2009524008A5 JP 2009524008 A5 JP2009524008 A5 JP 2009524008A5 JP 2008543520 A JP2008543520 A JP 2008543520A JP 2008543520 A JP2008543520 A JP 2008543520A JP 2009524008 A5 JP2009524008 A5 JP 2009524008A5
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- sample
- ibd
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- Prior art date
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- 238000000034 method Methods 0.000 claims description 24
- 208000022559 Inflammatory bowel disease Diseases 0.000 claims description 10
- 239000003550 marker Substances 0.000 claims 6
- 238000013528 artificial neural network Methods 0.000 claims 3
- 238000003018 immunoassay Methods 0.000 claims 3
- 238000007637 random forest analysis Methods 0.000 claims 3
- 206010009900 Colitis ulcerative Diseases 0.000 claims 2
- 208000011231 Crohn disease Diseases 0.000 claims 2
- 238000012896 Statistical algorithm Methods 0.000 claims 2
- 201000006704 Ulcerative Colitis Diseases 0.000 claims 2
- 230000001086 cytosolic effect Effects 0.000 claims 2
- 230000002055 immunohistochemical effect Effects 0.000 claims 2
- 102000016911 Deoxyribonucleases Human genes 0.000 claims 1
- 108010053770 Deoxyribonucleases Proteins 0.000 claims 1
- 238000002965 ELISA Methods 0.000 claims 1
- 102000004190 Enzymes Human genes 0.000 claims 1
- 108090000790 Enzymes Proteins 0.000 claims 1
- 101800004937 Protein C Proteins 0.000 claims 1
- 102100036546 Salivary acidic proline-rich phosphoprotein 1/2 Human genes 0.000 claims 1
- 101800001700 Saposin-D Proteins 0.000 claims 1
- 230000006978 adaptation Effects 0.000 claims 1
- 230000000844 anti-bacterial effect Effects 0.000 claims 1
- 230000000845 anti-microbial effect Effects 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 238000001514 detection method Methods 0.000 claims 1
- 238000003745 diagnosis Methods 0.000 claims 1
- 229940088598 enzyme Drugs 0.000 claims 1
- 238000010166 immunofluorescence Methods 0.000 claims 1
- 229940099472 immunoglobulin a Drugs 0.000 claims 1
- 229940027941 immunoglobulin g Drugs 0.000 claims 1
- 238000012308 immunohistochemistry method Methods 0.000 claims 1
- 230000003993 interaction Effects 0.000 claims 1
- 230000002452 interceptive effect Effects 0.000 claims 1
- 238000010801 machine learning Methods 0.000 claims 1
- 210000000440 neutrophil Anatomy 0.000 claims 1
- 229960000856 protein c Drugs 0.000 claims 1
- 238000012706 support-vector machine Methods 0.000 claims 1
- 208000024891 symptom Diseases 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11/293,616 US20060154276A1 (en) | 2004-05-13 | 2005-12-01 | Methods of diagnosing inflammatory bowel disease |
| US11/293,616 | 2005-12-01 | ||
| PCT/US2006/046136 WO2007064964A2 (en) | 2005-12-01 | 2006-11-30 | Methods of diagnosing inflammatory bowel disease |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009524008A JP2009524008A (ja) | 2009-06-25 |
| JP2009524008A5 true JP2009524008A5 (https=) | 2010-01-07 |
| JP5634023B2 JP5634023B2 (ja) | 2014-12-03 |
Family
ID=38092870
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008543520A Expired - Fee Related JP5634023B2 (ja) | 2005-12-01 | 2006-11-30 | 試料が炎症性腸疾患と関連しているか分類する方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20060154276A1 (https=) |
| EP (1) | EP1955070B1 (https=) |
| JP (1) | JP5634023B2 (https=) |
| AT (1) | ATE534911T1 (https=) |
| AU (1) | AU2006320384B2 (https=) |
| CA (1) | CA2632972C (https=) |
| IL (1) | IL191679A (https=) |
| WO (1) | WO2007064964A2 (https=) |
Families Citing this family (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7759079B2 (en) * | 2004-05-13 | 2010-07-20 | Prometheus Laboratories Inc. | Methods of diagnosing inflammatory bowel disease |
| US10544459B2 (en) | 2004-12-08 | 2020-01-28 | Cedars-Sinai Medical Center | Methods of using genetic variants for the diagnosis and treatment of inflammatory bowel disease |
| US20100021455A1 (en) * | 2004-12-08 | 2010-01-28 | Cedars-Sinai Medical Center | Methods for diagnosis and treatment of crohn's disease |
| WO2010048415A1 (en) * | 2008-10-22 | 2010-04-29 | Cedars-Sinai Medical Center | Methods of using jak3 genetic variants to diagnose and predict crohn's disease |
| US11268149B2 (en) | 2004-12-08 | 2022-03-08 | Cedars-Sinai Medical Center | Diagnosis and treatment of inflammatory bowel disease |
| US12110555B2 (en) | 2004-12-08 | 2024-10-08 | Cedars-Sinai Medical Center | Diagnosis and treatment of inflammatory bowel disease |
| US20080085524A1 (en) * | 2006-08-15 | 2008-04-10 | Prometheus Laboratories Inc. | Methods for diagnosing irritable bowel syndrome |
| US20100021917A1 (en) * | 2007-02-14 | 2010-01-28 | Cedars-Sinai Medical Center | Methods of using genes and genetic variants to predict or diagnose inflammatory bowel disease |
| WO2008106451A2 (en) * | 2007-02-26 | 2008-09-04 | Cedars-Sinai Medical Center | Methods of using single nucleotide polymorphisms in the tl1a gene to predict or diagnose inflammatory bowel disease |
| US20100055700A1 (en) * | 2007-02-28 | 2010-03-04 | Cedars-Sinai Medical Center | Role of il-12, il-23 and il-17 receptors in inflammatory bowel disease |
| US20100015156A1 (en) * | 2007-03-06 | 2010-01-21 | Cedars-Sinai Medical Center | Diagnosis of inflammatory bowel disease in children |
| WO2008116150A2 (en) * | 2007-03-21 | 2008-09-25 | Cedars-Sinai Medical Center | Ileal pouch-anal anastomosis (ipaa) factors in the treatment of inflammatory bowel disease |
| US20100184050A1 (en) * | 2007-04-26 | 2010-07-22 | Cedars-Sinai Medical Center | Diagnosis and treatment of inflammatory bowel disease in the puerto rican population |
| US20100144903A1 (en) * | 2007-05-04 | 2010-06-10 | Cedars-Sinai Medical Center | Methods of diagnosis and treatment of crohn's disease |
| US8153443B2 (en) * | 2007-05-10 | 2012-04-10 | Cedars-Sinai Medical Center | Characterization of the CBir1 antigenic response for diagnosis and treatment of Crohn's disease |
| US9305137B1 (en) | 2007-05-18 | 2016-04-05 | Cedars-Sinai Medical Center | Methods of identifying the genetic basis of a disease by a combinatorial genomics approach, biological pathway approach, and sequential approach |
| US11779571B2 (en) | 2008-02-26 | 2023-10-10 | Salix Pharmaceuticals, Inc. | Methods for treating irritable bowel syndrome (IBS) |
| PT2252148T (pt) | 2008-02-26 | 2020-01-23 | Salix Pharmaceuticals Ltd | Métodos de tratamento da síndrome do intestino irritável |
| WO2009143278A2 (en) * | 2008-05-20 | 2009-11-26 | Cedars-Sinai Medical Center | Methods of diagnosing and characterizing cannabinoid signaling in crohn's disease |
| US20110177969A1 (en) * | 2008-10-01 | 2011-07-21 | Cedars-Sinai Medical Center | The role of il17rd and the il23-1l17 pathway in crohn's disease |
| US8170804B2 (en) * | 2008-10-17 | 2012-05-01 | Roche Molecular Systems, Inc. | Determination of melting temperatures of DNA |
| JP5749652B2 (ja) * | 2008-11-11 | 2015-07-15 | ネステク ソシエテ アノニム | 血清学的マーカーを用いた炎症性腸疾患（ｉｂｄ）の予測方法 |
| US20110229471A1 (en) | 2008-11-26 | 2011-09-22 | Cedars-Sinai Medical Center | Methods of determining responsiveness to anti-tnf alpha therapy in inflammatory bowel disease |
| US9580752B2 (en) | 2008-12-24 | 2017-02-28 | Cedars-Sinai Medical Center | Methods of predicting medically refractive ulcerative colitis (MR-UC) requiring colectomy |
| KR101900016B1 (ko) | 2009-03-12 | 2018-09-20 | 캔서 프리벤션 앤 큐어, 리미티드 | 폐 질환의 동정, 평가, 예방 및 치료 방법과, 성별에 기초하는 질환의 동정, 평가, 예방 및 치료를 포함하는 상기 방법의 키트 |
| CA2758531C (en) * | 2009-04-14 | 2018-11-13 | Derren Barken | Inflammatory bowel disease prognostics |
| JP5414422B2 (ja) * | 2009-08-25 | 2014-02-12 | 日本電信電話株式会社 | 病原体検出方法 |
| BR112012005627A2 (pt) | 2009-09-13 | 2017-02-21 | Salix Pharmaceuticals Ltd | "uso de rifaximina para preparação de um medicamento para tratar síndrome do intestino irritável (ibs)" |
| EP3825693A1 (en) * | 2011-04-29 | 2021-05-26 | Cancer Prevention And Cure, Ltd. | Methods of identification and diagnosis of lung diseases using classification systems and kits thereof |
| WO2015067913A1 (en) | 2013-11-07 | 2015-05-14 | Diagnodus Limited | Biomarkers |
| SG11201401536QA (en) * | 2011-10-21 | 2014-05-29 | Nestec Sa | Methods for improving inflammatory bowel disease diagnosis |
| TWI596494B (zh) * | 2012-03-05 | 2017-08-21 | Ｏｐｋｏ診斷法有限責任公司 | 預測前列腺癌風險及前列腺腺體體積之方法及裝置 |
| CA2886991A1 (en) | 2012-10-05 | 2014-04-10 | Nestec S.A. | Antibodies to microbiome, stress factors and mast cell markers as diagnostic markers for ibs |
| KR102343212B1 (ko) | 2013-03-27 | 2021-12-23 | 세다르스-신나이 메디칼 센터 | Tl1a 기능 및 관련된 신호전달 경로의 저해에 의한 섬유증 및 염증의 완화 및 반전 |
| SG11201509371XA (en) * | 2013-05-24 | 2015-12-30 | Nestec Sa | Pathway specific markers for diagnosing irritable bowel syndrome |
| WO2015010108A1 (en) | 2013-07-19 | 2015-01-22 | Cedars-Sinai Medical Center | Signature of tl1a (tnfsf15) signaling pathway |
| US12326453B2 (en) | 2014-03-28 | 2025-06-10 | Opko Diagnostics, Llc | Compositions and methods for active surveillance of prostate cancer |
| KR102505543B1 (ko) | 2014-03-28 | 2023-03-02 | 옵코 다이어그노스틱스, 엘엘씨 | 전립선암 진단에 관한 조성물 및 방법 |
| PT3253800T (pt) | 2015-03-27 | 2021-04-28 | Opko Diagnostics Llc | Padrões de antigénio da próstata e suas utilizações |
| CN106446599A (zh) * | 2015-08-11 | 2017-02-22 | 中国科学院青岛生物能源与过程研究所 | 一种筛选婴幼儿龋病的口腔致病性生物标记物的方法 |
| AU2016349703A1 (en) | 2015-11-06 | 2018-11-01 | Vetica Labs, Inc. | Methods of detecting inflammatory markers and treating inflammatory conditions in companion animals |
| US11186872B2 (en) | 2016-03-17 | 2021-11-30 | Cedars-Sinai Medical Center | Methods of diagnosing inflammatory bowel disease through RNASET2 |
| US10444213B2 (en) | 2016-08-25 | 2019-10-15 | Viavi Solutions Inc. | Spectroscopic classification of conformance with dietary restrictions |
| CN110709936A (zh) | 2017-04-04 | 2020-01-17 | 肺癌蛋白质组学有限责任公司 | 用于早期肺癌预后的基于血浆的蛋白质概况分析 |
| US12431244B2 (en) | 2018-08-07 | 2025-09-30 | Yale University | Interpretable deep machine learning for clinical radiology |
| WO2020077163A1 (en) * | 2018-10-10 | 2020-04-16 | Kiljanek Lukasz R | Generation of simulated patient data for training predicted medical outcome analysis engine |
| WO2023102071A1 (en) * | 2021-12-01 | 2023-06-08 | Cedars-Sinai Medical Center | Microbial metabolites on intestinal inflammation |
Family Cites Families (28)
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|---|---|---|---|---|
| US4277250A (en) | 1979-12-10 | 1981-07-07 | Baylor College Of Medicine | Methods for detecting and quantifying occult blood |
| JPH0684970B2 (ja) | 1987-03-31 | 1994-10-26 | 株式会社京都医科学研究所 | 糞便中の潜血検出方法 |
| US5081040A (en) | 1987-06-29 | 1992-01-14 | Helena Laboratories Corporation | Composition and kit for testing for occult blood in human and animal excretions, fluids, or tissue matrixes |
| JPH0736013B2 (ja) | 1991-04-27 | 1995-04-19 | 一男 田畑 | 潜血検出用試薬 |
| US5885527A (en) | 1992-05-21 | 1999-03-23 | Biosite Diagnostics, Inc. | Diagnostic devices and apparatus for the controlled movement of reagents without membrances |
| US5830675A (en) * | 1993-03-10 | 1998-11-03 | Cedars-Sinai Medical Center | Methods for selectively detecting perinuclear anti-neutrophil cytoplasmic antibody of ulcerative colitis, primary sclerosing cholangitis, or type 1 autoimmune hepatitis |
| EP0615129B1 (en) * | 1993-03-10 | 2000-05-31 | Cedars-Sinai Medical Center | Methods for selectively detecting perinuclear anti-neutrophil cytoplasmic antibody of ulcerative colitis or primary sclerosing cholangitis |
| US6033864A (en) | 1996-04-12 | 2000-03-07 | The Regents Of The University Of California | Diagnosis, prevention and treatment of ulcerative colitis, and clinical subtypes thereof, using microbial UC pANCA antigens |
| US6074835A (en) | 1996-04-12 | 2000-06-13 | Regents Of The Univ. Of California | Diagnosis, prevention and treatment of ulcerative colitis, and clinical subtypes thereof, using histone H1 |
| US6218129B1 (en) * | 1998-05-15 | 2001-04-17 | Prometheus Laboratories, Inc. | Inflammatory bowel disease first step assay system |
| US6406862B1 (en) | 1998-10-06 | 2002-06-18 | The United States Of America As Represented By The Secretary Of The Army | Dip-stick assay for C-reactive protein |
| US6309643B1 (en) * | 1999-04-30 | 2001-10-30 | The Regents Of The University Of California | IBD-associated microbial antigens and methods of using same |
| FR2802536B1 (fr) | 1999-11-23 | 2003-06-13 | Chru Lille | Oligomannosides de synthese, leur preparation et leur utilisation a la detection d'anticorps et a la prevention d'infections |
| FR2806739B1 (fr) | 2000-03-27 | 2005-02-18 | Fond Jean Dausset Ceph | Genes impliques dans les maladies inflammatoires de l'intestin et leur utilisation |
| US6838250B2 (en) | 2000-03-31 | 2005-01-04 | Ortho-Clinical Diagnostics, Inc. | Immunoassay for C-reactive protein |
| US7138237B1 (en) | 2000-05-19 | 2006-11-21 | Cedars-Sinai Medical Center | Diagnosis, prevention and treatment of Crohn's disease using the OmpC antigen |
| US20050164929A1 (en) * | 2000-11-06 | 2005-07-28 | Lupine Logic, Inc. | Methods of preventing and treating inflammatory bowel disease |
| AU2002220029B2 (en) | 2000-11-14 | 2007-09-06 | Techlab, Inc. | Method for differentiating between irritable bowel syndrome and inflammatory bowel disease using lactoferrin as marker |
| CA2860702C (en) | 2001-12-17 | 2019-02-26 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of inflammatory bowel disease |
| US20030204507A1 (en) * | 2002-04-25 | 2003-10-30 | Li Jonathan Qiang | Classification of rare events with high reliability |
| AU2003284187B2 (en) | 2002-10-25 | 2009-10-01 | Techlab, Inc. | Inflammatory bowel disease and irritable bowel syndrome IBD-first chek diagnostic panel |
| WO2004048600A2 (en) | 2002-11-22 | 2004-06-10 | Emory University | Diagnostic tests and methods for diagnosing inflammatory bowel disease |
| US7662569B2 (en) * | 2003-04-11 | 2010-02-16 | Cedars-Sinai Medical Center | Methods of assessing Crohn's disease patient phenotype by I2 serologic response |
| KR100731693B1 (ko) * | 2003-04-23 | 2007-06-25 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | 질환 예후 모델의 작성 방법, 이 모델을 이용한 질환 예후예측 방법, 이 모델에 의한 예후 예측 장치, 및 그의프로그램ㆍ기억 매체 |
| US20040242972A1 (en) * | 2003-05-28 | 2004-12-02 | General Electric Company | Method, system and computer product for prognosis of a medical disorder |
| CA2549971A1 (en) | 2003-11-03 | 2005-05-12 | Duke University | Methods of identifying individuals at risk of perioperative bleeding, renal dysfunction or stroke |
| EP1723432A1 (en) * | 2004-02-05 | 2006-11-22 | Medtronic, Inc. | Methods and apparatus for identifying patients at risk for life threatening arrhythmias |
| WO2006012472A1 (en) | 2004-07-21 | 2006-02-02 | Qualyst, Inc. | Apparatus, kits and methods for evaluating binding interactions, for detecting and quantifying binding molecules, and for sample preparation |
-
2005
- 2005-12-01 US US11/293,616 patent/US20060154276A1/en active Pending
-
2006
- 2006-11-30 JP JP2008543520A patent/JP5634023B2/ja not_active Expired - Fee Related
- 2006-11-30 WO PCT/US2006/046136 patent/WO2007064964A2/en not_active Ceased
- 2006-11-30 AU AU2006320384A patent/AU2006320384B2/en not_active Ceased
- 2006-11-30 EP EP06838862A patent/EP1955070B1/en not_active Not-in-force
- 2006-11-30 CA CA2632972A patent/CA2632972C/en active Active
- 2006-11-30 AT AT06838862T patent/ATE534911T1/de active
-
2008
- 2008-05-25 IL IL191679A patent/IL191679A/en not_active IP Right Cessation
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