ATE534911T1 - Verfahren zur diagnostizierung einer entzündlichen darmerkrankung - Google Patents

Verfahren zur diagnostizierung einer entzündlichen darmerkrankung

Info

Publication number
ATE534911T1
ATE534911T1 AT06838862T AT06838862T ATE534911T1 AT E534911 T1 ATE534911 T1 AT E534911T1 AT 06838862 T AT06838862 T AT 06838862T AT 06838862 T AT06838862 T AT 06838862T AT E534911 T1 ATE534911 T1 AT E534911T1
Authority
AT
Austria
Prior art keywords
ibd
individual
inflammatory bowel
level
bowel disease
Prior art date
Application number
AT06838862T
Other languages
English (en)
Inventor
Augusto Lois
Bruce Neri
Original Assignee
Prometheus Lab Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Prometheus Lab Inc filed Critical Prometheus Lab Inc
Application granted granted Critical
Publication of ATE534911T1 publication Critical patent/ATE534911T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/06—Gastro-intestinal diseases
    • G01N2800/065—Bowel diseases, e.g. Crohn, ulcerative colitis, IBS
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
AT06838862T 2005-12-01 2006-11-30 Verfahren zur diagnostizierung einer entzündlichen darmerkrankung ATE534911T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/293,616 US20060154276A1 (en) 2004-05-13 2005-12-01 Methods of diagnosing inflammatory bowel disease
PCT/US2006/046136 WO2007064964A2 (en) 2005-12-01 2006-11-30 Methods of diagnosing inflammatory bowel disease

Publications (1)

Publication Number Publication Date
ATE534911T1 true ATE534911T1 (de) 2011-12-15

Family

ID=38092870

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06838862T ATE534911T1 (de) 2005-12-01 2006-11-30 Verfahren zur diagnostizierung einer entzündlichen darmerkrankung

Country Status (8)

Country Link
US (1) US20060154276A1 (de)
EP (1) EP1955070B1 (de)
JP (1) JP5634023B2 (de)
AT (1) ATE534911T1 (de)
AU (1) AU2006320384B2 (de)
CA (1) CA2632972C (de)
IL (1) IL191679A (de)
WO (1) WO2007064964A2 (de)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7759079B2 (en) * 2004-05-13 2010-07-20 Prometheus Laboratories Inc. Methods of diagnosing inflammatory bowel disease
US11268149B2 (en) 2004-12-08 2022-03-08 Cedars-Sinai Medical Center Diagnosis and treatment of inflammatory bowel disease
WO2008109782A2 (en) * 2007-03-06 2008-09-12 Cedars-Sinai Medical Center Diagnosis of inflammatory bowel disease in children
WO2008101133A2 (en) * 2007-02-14 2008-08-21 Cedars-Sinai Medical Center Methods of using genes and genetic variants to predict or diagnose inflammatory bowel disease
WO2010048415A1 (en) * 2008-10-22 2010-04-29 Cedars-Sinai Medical Center Methods of using jak3 genetic variants to diagnose and predict crohn's disease
EP2270512B1 (de) * 2004-12-08 2016-03-23 Cedars-Sinai Medical Center Verfahren zur Diagnose von Morbus Crohn
US10544459B2 (en) 2004-12-08 2020-01-28 Cedars-Sinai Medical Center Methods of using genetic variants for the diagnosis and treatment of inflammatory bowel disease
US20080085524A1 (en) * 2006-08-15 2008-04-10 Prometheus Laboratories Inc. Methods for diagnosing irritable bowel syndrome
US20100190162A1 (en) * 2007-02-26 2010-07-29 Cedars-Sinai Medical Center Methods of using single nucleotide polymorphisms in the tl1a gene to predict or diagnose inflammatory bowel disease
WO2008106579A2 (en) * 2007-02-28 2008-09-04 Cedars-Sinai Medical Center The role of il-12, il-23 and il-17 receptors in inflammatory bowel disease
WO2008116150A2 (en) * 2007-03-21 2008-09-25 Cedars-Sinai Medical Center Ileal pouch-anal anastomosis (ipaa) factors in the treatment of inflammatory bowel disease
US20100184050A1 (en) * 2007-04-26 2010-07-22 Cedars-Sinai Medical Center Diagnosis and treatment of inflammatory bowel disease in the puerto rican population
US20100144903A1 (en) * 2007-05-04 2010-06-10 Cedars-Sinai Medical Center Methods of diagnosis and treatment of crohn's disease
US8153443B2 (en) * 2007-05-10 2012-04-10 Cedars-Sinai Medical Center Characterization of the CBir1 antigenic response for diagnosis and treatment of Crohn's disease
US9305137B1 (en) 2007-05-18 2016-04-05 Cedars-Sinai Medical Center Methods of identifying the genetic basis of a disease by a combinatorial genomics approach, biological pathway approach, and sequential approach
KR20100122937A (ko) 2008-02-26 2010-11-23 샐릭스 파마슈티컬스 리미티드 장 질환의 치료 방법
US11779571B2 (en) 2008-02-26 2023-10-10 Salix Pharmaceuticals, Inc. Methods for treating irritable bowel syndrome (IBS)
US20110124644A1 (en) * 2008-05-20 2011-05-26 Cedars-Sinai Medical Center Methods of diagnosing and characterizing cannabinoid signaling in crohn's disease
US20110177969A1 (en) * 2008-10-01 2011-07-21 Cedars-Sinai Medical Center The role of il17rd and the il23-1l17 pathway in crohn's disease
US8170804B2 (en) * 2008-10-17 2012-05-01 Roche Molecular Systems, Inc. Determination of melting temperatures of DNA
EP2359137A4 (de) 2008-11-11 2012-05-30 Prometheus Lab Inc Verfahren zur vorhersage einer entzündlichen darmerkrankung (ibd) anhand serologischer marker
WO2010062960A2 (en) 2008-11-26 2010-06-03 Cedars-Sinai Medical Center METHODS OF DETERMINING RESPONSIVENESS TO ANTI-TNFα THERAPY IN INFLAMMATORY BOWEL DISEASE
US9580752B2 (en) 2008-12-24 2017-02-28 Cedars-Sinai Medical Center Methods of predicting medically refractive ulcerative colitis (MR-UC) requiring colectomy
ES2703714T3 (es) 2009-03-12 2019-03-12 Cancer Prevention & Cure Ltd Métodos de identificación, evaluación, prevención y terapia de enfermedades pulmonares y kits de los mismos, incluida la identificación, evaluación, prevención y terapia de enfermedades en base al género
ES2553415T3 (es) * 2009-04-14 2015-12-09 Nestec S.A. Método de pronóstico de la enfermedad intestinal inflamatoria
JP5414422B2 (ja) * 2009-08-25 2014-02-12 日本電信電話株式会社 病原体検出方法
EP2475392A4 (de) 2009-09-13 2013-01-09 Salix Pharmaceuticals Ltd Verfahren zur behandlung des reizdarmsyndroms
CN110444287B (zh) * 2011-04-29 2024-02-06 癌症预防和治疗有限公司 使用分类系统及其试剂盒识别和诊断肺部疾病的方法
WO2015067913A1 (en) 2013-11-07 2015-05-14 Diagnodus Limited Biomarkers
MX352274B (es) * 2011-10-21 2017-11-16 Nestec Sa Metodos para mejorar el diagnostico de enfermedad inflamatoria intestinal.
MY193914A (en) 2012-03-05 2022-11-01 Oy Arctic Partners Ab Methods and apparatuses for predicting risk of prostate cancer and prostate gland volume
CA2886991A1 (en) 2012-10-05 2014-04-10 Nestec S.A. Antibodies to microbiome, stress factors and mast cell markers as diagnostic markers for ibs
KR20210157418A (ko) 2013-03-27 2021-12-28 세다르스-신나이 메디칼 센터 Tl1a 기능 및 관련된 신호전달 경로의 저해에 의한 섬유증 및 염증의 완화 및 반전
MX367046B (es) * 2013-05-24 2019-08-02 Soc Des Produits Nestle S A Star Marcadores especificos de via para diagnosticar sindrome del intestino irritable.
EP3022295A4 (de) 2013-07-19 2017-03-01 Cedars-Sinai Medical Center Signatur des tl1a (tnfsf15)-signalweges
JP6775488B2 (ja) 2014-03-28 2020-10-28 オプコ・ダイアグノスティクス・リミテッド・ライアビリティ・カンパニーＯｐｋｏ Ｄｉａｇｎｏｓｔｉｃｓ，Ｌｌｃ 前立腺がんの診断に関連する組成物および方法
PL3253800T3 (pl) 2015-03-27 2021-08-23 Opko Diagnostics, Llc Standardy antygenów prostaty i ich zastosowanie
CN106446599A (zh) * 2015-08-11 2017-02-22 中国科学院青岛生物能源与过程研究所 一种筛选婴幼儿龋病的口腔致病性生物标记物的方法
AU2016349703A1 (en) 2015-11-06 2018-11-01 Vetica Labs, Inc. Methods of detecting inflammatory markers and treating inflammatory conditions in companion animals
US11186872B2 (en) 2016-03-17 2021-11-30 Cedars-Sinai Medical Center Methods of diagnosing inflammatory bowel disease through RNASET2
US10444213B2 (en) 2016-08-25 2019-10-15 Viavi Solutions Inc. Spectroscopic classification of conformance with dietary restrictions
WO2018187496A2 (en) 2017-04-04 2018-10-11 Lung Cancer Proteomics, Llc Plasma based protein profiling for early stage lung cancer prognosis
US20210174154A1 (en) * 2018-08-07 2021-06-10 Yale University Interpretable deep machine learning for clinical radio;ogy
US20200118691A1 (en) * 2018-10-10 2020-04-16 Lukasz R. Kiljanek Generation of Simulated Patient Data for Training Predicted Medical Outcome Analysis Engine
WO2023102071A1 (en) * 2021-12-01 2023-06-08 Cedars-Sinai Medical Center Microbial metabolites on intestinal inflammation

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4277250A (en) 1979-12-10 1981-07-07 Baylor College Of Medicine Methods for detecting and quantifying occult blood
JPH0684970B2 (ja) 1987-03-31 1994-10-26 株式会社京都医科学研究所 糞便中の潜血検出方法
US5081040A (en) 1987-06-29 1992-01-14 Helena Laboratories Corporation Composition and kit for testing for occult blood in human and animal excretions, fluids, or tissue matrixes
JPH0736013B2 (ja) 1991-04-27 1995-04-19 一男 田畑 潜血検出用試薬
US5885527A (en) 1992-05-21 1999-03-23 Biosite Diagnostics, Inc. Diagnostic devices and apparatus for the controlled movement of reagents without membrances
US5830675A (en) 1993-03-10 1998-11-03 Cedars-Sinai Medical Center Methods for selectively detecting perinuclear anti-neutrophil cytoplasmic antibody of ulcerative colitis, primary sclerosing cholangitis, or type 1 autoimmune hepatitis
DE69424700T2 (de) * 1993-03-10 2000-11-09 Cedars Sinai Medical Center Lo Verfahren zum selektiven Nachweis von perinuklearen anti-neutrophilen cytoplasmischen Antikörpern bei ulzerativen Kolitis oder primärer sclerotischer Cholangitis
US6074835A (en) 1996-04-12 2000-06-13 Regents Of The Univ. Of California Diagnosis, prevention and treatment of ulcerative colitis, and clinical subtypes thereof, using histone H1
US6033864A (en) 1996-04-12 2000-03-07 The Regents Of The University Of California Diagnosis, prevention and treatment of ulcerative colitis, and clinical subtypes thereof, using microbial UC pANCA antigens
US6218129B1 (en) * 1998-05-15 2001-04-17 Prometheus Laboratories, Inc. Inflammatory bowel disease first step assay system
US6406862B1 (en) 1998-10-06 2002-06-18 The United States Of America As Represented By The Secretary Of The Army Dip-stick assay for C-reactive protein
US6309643B1 (en) * 1999-04-30 2001-10-30 The Regents Of The University Of California IBD-associated microbial antigens and methods of using same
FR2802536B1 (fr) 1999-11-23 2003-06-13 Chru Lille Oligomannosides de synthese, leur preparation et leur utilisation a la detection d'anticorps et a la prevention d'infections
FR2806739B1 (fr) 2000-03-27 2005-02-18 Fond Jean Dausset Ceph Genes impliques dans les maladies inflammatoires de l'intestin et leur utilisation
US6838250B2 (en) 2000-03-31 2005-01-04 Ortho-Clinical Diagnostics, Inc. Immunoassay for C-reactive protein
US7138237B1 (en) 2000-05-19 2006-11-21 Cedars-Sinai Medical Center Diagnosis, prevention and treatment of Crohn's disease using the OmpC antigen
US20050164929A1 (en) * 2000-11-06 2005-07-28 Lupine Logic, Inc. Methods of preventing and treating inflammatory bowel disease
EP2071332A1 (de) 2000-11-14 2009-06-17 Techlab, Inc. Verfahren zum Überwachen von Personen mit entzündlicher Darmerkrankung unter Verwendung des gesamten endogenen Lactoferrins als Marker
DK1581119T3 (da) 2001-12-17 2013-05-13 Corixa Corp Sammensætninger og fremgangsmåder til terapi og diagnose af inflammatoriske tarmsygdomme
US20030204507A1 (en) * 2002-04-25 2003-10-30 Li Jonathan Qiang Classification of rare events with high reliability
EP1554580B1 (de) 2002-10-25 2008-05-14 Techlab, Inc. Diagnostisches panel ibd-first chek fur entzundliche darmerkrankung (ibd) und reizkolon
US20070275424A1 (en) * 2002-11-22 2007-11-29 Andrew Gewirtz Diagnostic Tests and Methods for Diagnosing Inflammatory Bowel Disease
US7662569B2 (en) * 2003-04-11 2010-02-16 Cedars-Sinai Medical Center Methods of assessing Crohn's disease patient phenotype by I2 serologic response
KR100731693B1 (ko) * 2003-04-23 2007-06-25 에자이 알앤드디 매니지먼트 가부시키가이샤 질환 예후 모델의 작성 방법, 이 모델을 이용한 질환 예후예측 방법, 이 모델에 의한 예후 예측 장치, 및 그의프로그램ㆍ기억 매체
US20040242972A1 (en) * 2003-05-28 2004-12-02 General Electric Company Method, system and computer product for prognosis of a medical disorder
WO2005041896A2 (en) 2003-11-03 2005-05-12 Duke University Methods of identifying individuals at risk of perioperative bleeding, renal dysfunction or stroke
JP2007523324A (ja) * 2004-02-05 2007-08-16 メドトロニック・インコーポレーテッド 命にかかわる不整脈のリスク状態にある患者を識別する方法及び装置
US20060019410A1 (en) 2004-07-21 2006-01-26 Qualyst, Inc. Apparatus, kits and methods for evaluating binding interactions, for detecting and quantifying binding molecules, and for sample preparation

Also Published As

Publication number Publication date
EP1955070B1 (de) 2011-11-23
WO2007064964A3 (en) 2007-12-06
CA2632972A1 (en) 2007-06-07
AU2006320384B2 (en) 2012-11-29
EP1955070A2 (de) 2008-08-13
JP5634023B2 (ja) 2014-12-03
IL191679A0 (en) 2008-12-29
IL191679A (en) 2011-12-29
JP2009524008A (ja) 2009-06-25
EP1955070A4 (de) 2009-06-03
AU2006320384A1 (en) 2007-06-07
WO2007064964A2 (en) 2007-06-07
CA2632972C (en) 2017-02-21
US20060154276A1 (en) 2006-07-13

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