JP2009523140A - 瘢痕形成または血管形成効果を有する医薬の製造のためのトリアジン誘導体の使用 - Google Patents
瘢痕形成または血管形成効果を有する医薬の製造のためのトリアジン誘導体の使用 Download PDFInfo
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- JP2009523140A JP2009523140A JP2008549781A JP2008549781A JP2009523140A JP 2009523140 A JP2009523140 A JP 2009523140A JP 2008549781 A JP2008549781 A JP 2008549781A JP 2008549781 A JP2008549781 A JP 2008549781A JP 2009523140 A JP2009523140 A JP 2009523140A
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- alkoxy
- alkyl
- aryl
- halogen
- amino
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D251/00—Heterocyclic compounds containing 1,3,5-triazine rings
- C07D251/02—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
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- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
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- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
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- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Diabetes (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Inorganic Chemistry (AREA)
- Cardiology (AREA)
- Virology (AREA)
- Hematology (AREA)
- Emergency Medicine (AREA)
- Obesity (AREA)
- Heart & Thoracic Surgery (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Steroid Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0600347A FR2896161B1 (fr) | 2006-01-13 | 2006-01-13 | Utilisation de derives de triazines pour fabriquer un medicament ayant un effet cicatrisant ou angiogenique. |
| PCT/EP2006/012183 WO2007079915A2 (en) | 2006-01-13 | 2006-12-18 | Use of triazine derivatives for the manufacture of a medicament having a cicatrising or angiogenic effect |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009523140A true JP2009523140A (ja) | 2009-06-18 |
| JP2009523140A5 JP2009523140A5 (enExample) | 2010-02-12 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008549781A Pending JP2009523140A (ja) | 2006-01-13 | 2006-12-18 | 瘢痕形成または血管形成効果を有する医薬の製造のためのトリアジン誘導体の使用 |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US8217040B2 (enExample) |
| EP (1) | EP1971329B1 (enExample) |
| JP (1) | JP2009523140A (enExample) |
| KR (1) | KR101482686B1 (enExample) |
| CN (1) | CN101355931A (enExample) |
| AR (1) | AR059034A1 (enExample) |
| AU (1) | AU2006334732B2 (enExample) |
| BR (1) | BRPI0620983B8 (enExample) |
| CA (1) | CA2636838C (enExample) |
| CY (1) | CY1119872T1 (enExample) |
| DK (1) | DK1971329T3 (enExample) |
| EA (1) | EA016127B1 (enExample) |
| ES (1) | ES2647912T3 (enExample) |
| FR (1) | FR2896161B1 (enExample) |
| HU (1) | HUE037217T2 (enExample) |
| IL (1) | IL192595A (enExample) |
| LT (1) | LT1971329T (enExample) |
| PL (1) | PL1971329T3 (enExample) |
| PT (1) | PT1971329T (enExample) |
| SI (1) | SI1971329T1 (enExample) |
| WO (1) | WO2007079915A2 (enExample) |
| ZA (1) | ZA200806946B (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2012533529A (ja) * | 2009-07-17 | 2012-12-27 | ポクセル・エスアーエス | 虚血および／または再灌流関連疾患の処置に使用されるジヒドロ−１，３，５−トリアジンのアミノ誘導体 |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2020536121A (ja) | 2017-10-02 | 2020-12-10 | ポクセルＰｏｘｅｌ | 駆出率が保持された心不全を治療する方法 |
| CA3102412A1 (en) | 2018-06-06 | 2019-12-12 | Metavant Sciences Gmbh | Methods of treating subjects having diabetes with chronic kidney disease |
| WO2019238647A1 (en) | 2018-06-14 | 2019-12-19 | Poxel | Film-coated tablet comprising a triazine derivative for use in the treatment of diabetes |
| EP4014962A1 (de) * | 2020-12-16 | 2022-06-22 | Novigo GmbH & Co. KG | Zusammensetzung mit osmotisch wirksamer substanz und verwendung der zusammensetzung |
| FR3149774B1 (fr) * | 2024-01-11 | 2025-06-20 | Fabre Pierre Dermo Cosmetique | 5,6,5’,6’-tétraphényl-3,3’-(1,4-phénylène)-bis[1,2,4]triazine pour améliorer l’aspect des cicatrices et/ou réduire les marques cicatricielles |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| JP2003520858A (ja) * | 2000-01-26 | 2003-07-08 | リファ | ジヒドロ−１，３，５−トリアジンのアミン含有誘導体およびそれらの治療用用途 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6150362A (en) * | 1997-12-12 | 2000-11-21 | Henkin; Jack | Triazine angiogenesis inhibitors |
| DK1037886T3 (da) * | 1997-12-12 | 2003-08-25 | Abbott Lab | Triazin angiogeneseinhibitorer |
| AU2003289375A1 (en) * | 2002-12-17 | 2004-07-09 | Hamari Chemicals, Ltd | Novel 2,4-diamino-1,3,5-triazine derivative |
| FR2853650B1 (fr) * | 2003-04-10 | 2006-07-07 | Merck Sante Sas | Procede de dedoublement d'amines utiles pour le traitement de desordres associes au syndrome d'insulino-resistance |
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2006
- 2006-01-13 FR FR0600347A patent/FR2896161B1/fr not_active Expired - Fee Related
- 2006-12-18 CA CA2636838A patent/CA2636838C/en not_active Expired - Fee Related
- 2006-12-18 US US12/160,515 patent/US8217040B2/en not_active Expired - Fee Related
- 2006-12-18 PT PT68297043T patent/PT1971329T/pt unknown
- 2006-12-18 LT LTEP06829704.3T patent/LT1971329T/lt unknown
- 2006-12-18 WO PCT/EP2006/012183 patent/WO2007079915A2/en not_active Ceased
- 2006-12-18 JP JP2008549781A patent/JP2009523140A/ja active Pending
- 2006-12-18 ES ES06829704.3T patent/ES2647912T3/es active Active
- 2006-12-18 BR BRPI0620983A patent/BRPI0620983B8/pt not_active IP Right Cessation
- 2006-12-18 CN CNA200680050807XA patent/CN101355931A/zh active Pending
- 2006-12-18 AU AU2006334732A patent/AU2006334732B2/en not_active Ceased
- 2006-12-18 SI SI200632225T patent/SI1971329T1/en unknown
- 2006-12-18 PL PL06829704T patent/PL1971329T3/pl unknown
- 2006-12-18 EP EP06829704.3A patent/EP1971329B1/en active Active
- 2006-12-18 KR KR1020087019389A patent/KR101482686B1/ko not_active Expired - Fee Related
- 2006-12-18 DK DK06829704.3T patent/DK1971329T3/en active
- 2006-12-18 EA EA200801678A patent/EA016127B1/ru not_active IP Right Cessation
- 2006-12-18 HU HUE06829704A patent/HUE037217T2/hu unknown
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2007
- 2007-01-12 AR ARP070100140A patent/AR059034A1/es unknown
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2008
- 2008-07-02 IL IL192595A patent/IL192595A/en active IP Right Grant
- 2008-08-12 ZA ZA200806946A patent/ZA200806946B/xx unknown
-
2017
- 2017-11-27 CY CY20171101240T patent/CY1119872T1/el unknown
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2003520858A (ja) * | 2000-01-26 | 2003-07-08 | リファ | ジヒドロ−１，３，５−トリアジンのアミン含有誘導体およびそれらの治療用用途 |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2012533529A (ja) * | 2009-07-17 | 2012-12-27 | ポクセル・エスアーエス | 虚血および／または再灌流関連疾患の処置に使用されるジヒドロ−１，３，５−トリアジンのアミノ誘導体 |
Also Published As
| Publication number | Publication date |
|---|---|
| SI1971329T1 (en) | 2018-03-30 |
| WO2007079915A2 (en) | 2007-07-19 |
| BRPI0620983B8 (pt) | 2021-05-25 |
| ZA200806946B (en) | 2009-11-25 |
| BRPI0620983A2 (pt) | 2011-11-29 |
| AU2006334732B2 (en) | 2012-05-17 |
| CN101355931A (zh) | 2009-01-28 |
| EP1971329A2 (en) | 2008-09-24 |
| CA2636838A1 (en) | 2007-07-19 |
| PT1971329T (pt) | 2017-11-24 |
| ES2647912T3 (es) | 2017-12-27 |
| PL1971329T3 (pl) | 2018-03-30 |
| EP1971329B1 (en) | 2017-10-11 |
| HUE037217T2 (hu) | 2018-08-28 |
| AR059034A1 (es) | 2008-03-12 |
| EA200801678A1 (ru) | 2008-12-30 |
| EA016127B1 (ru) | 2012-02-28 |
| DK1971329T3 (en) | 2017-12-04 |
| KR101482686B1 (ko) | 2015-01-14 |
| BRPI0620983B1 (pt) | 2019-09-17 |
| FR2896161B1 (fr) | 2008-04-04 |
| LT1971329T (lt) | 2018-01-25 |
| WO2007079915A3 (en) | 2007-08-30 |
| IL192595A0 (en) | 2009-02-11 |
| IL192595A (en) | 2013-04-30 |
| US20100168115A1 (en) | 2010-07-01 |
| CA2636838C (en) | 2015-05-05 |
| FR2896161A1 (fr) | 2007-07-20 |
| US8217040B2 (en) | 2012-07-10 |
| AU2006334732A1 (en) | 2007-07-19 |
| KR20080088629A (ko) | 2008-10-02 |
| CY1119872T1 (el) | 2018-06-27 |
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