JP2009521672A - 生体分子の調製 - Google Patents

生体分子の調製 Download PDF

Info

Publication number
JP2009521672A
JP2009521672A JP2008547172A JP2008547172A JP2009521672A JP 2009521672 A JP2009521672 A JP 2009521672A JP 2008547172 A JP2008547172 A JP 2008547172A JP 2008547172 A JP2008547172 A JP 2008547172A JP 2009521672 A JP2009521672 A JP 2009521672A
Authority
JP
Japan
Prior art keywords
phase
polymer
liquid
solid phase
protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2008547172A
Other languages
English (en)
Japanese (ja)
Other versions
JP2009521672A5 (https=
Inventor
ハルグレン,エリザベス
パルムグレン,ロニー
スベンソン,リンダ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cytiva Sweden AB
Original Assignee
Amersham Bioscience AB
GE Healthcare Bio Sciences Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amersham Bioscience AB, GE Healthcare Bio Sciences Corp filed Critical Amersham Bioscience AB
Publication of JP2009521672A publication Critical patent/JP2009521672A/ja
Publication of JP2009521672A5 publication Critical patent/JP2009521672A5/ja
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/16Extraction; Separation; Purification by chromatography
    • C07K1/20Partition-, reverse-phase or hydrophobic interaction chromatography

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
JP2008547172A 2005-12-22 2006-12-21 生体分子の調製 Pending JP2009521672A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE0502910 2005-12-22
PCT/SE2006/001479 WO2007073311A1 (en) 2005-12-22 2006-12-21 Preparation of biomolecules

Publications (2)

Publication Number Publication Date
JP2009521672A true JP2009521672A (ja) 2009-06-04
JP2009521672A5 JP2009521672A5 (https=) 2010-01-28

Family

ID=38188936

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008547172A Pending JP2009521672A (ja) 2005-12-22 2006-12-21 生体分子の調製

Country Status (6)

Country Link
US (1) US8263343B2 (https=)
EP (1) EP1976609A4 (https=)
JP (1) JP2009521672A (https=)
AU (1) AU2006327328B2 (https=)
CA (1) CA2632328A1 (https=)
WO (1) WO2007073311A1 (https=)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011106857A (ja) * 2009-11-13 2011-06-02 Toppan Forms Co Ltd 化学物質の分離キット及び分離方法
JP2011179848A (ja) * 2010-02-26 2011-09-15 Toppan Forms Co Ltd 化学物質の分離キット及び分離方法
JP2014161833A (ja) * 2013-02-27 2014-09-08 Mitsubishi Chemicals Corp タンパク質用アフィニティ分離剤
JP2015052613A (ja) * 2010-08-27 2015-03-19 インターベット インターナショナル ベー. フェー. ワクチン製剤についての効力試験

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2902799B1 (fr) 2006-06-27 2012-10-26 Millipore Corp Procede et unite de preparation d'un echantillon pour l'analyse microbiologique d'un liquide
US8569464B2 (en) 2006-12-21 2013-10-29 Emd Millipore Corporation Purification of proteins
WO2008079302A2 (en) 2006-12-21 2008-07-03 Millipore Corporation Purification of proteins
US8362217B2 (en) 2006-12-21 2013-01-29 Emd Millipore Corporation Purification of proteins
WO2008156409A1 (en) * 2007-06-19 2008-12-24 Ge Healthcare Bio-Sciences Ab Separation method using polymer multi phase systems
US8999702B2 (en) 2008-06-11 2015-04-07 Emd Millipore Corporation Stirred tank bioreactor
JP2012511929A (ja) 2008-12-16 2012-05-31 イー・エム・デイー・ミリポア・コーポレイシヨン 攪拌タンク反応器及び方法
CA2748807C (en) * 2009-01-08 2019-01-29 Ge Healthcare Bio-Sciences Ab Separation method using single polymer phase systems
CN102762585B (zh) * 2010-02-12 2016-01-20 DPx控股有限公司 单一单元抗体纯化
WO2011146394A1 (en) 2010-05-17 2011-11-24 Millipore Corporation Stimulus responsive polymers for the purification of biomolecules
US9169379B2 (en) 2013-07-15 2015-10-27 King Fahd University Of Petroleum And Minerals Aqueous two-phase systems
US9828599B2 (en) 2013-09-18 2017-11-28 General Electric Company Methods of selecting binding-elements and uses thereof
US10359419B2 (en) 2013-10-02 2019-07-23 General Electric Company Methods for detection of target using affinity binding
US20150093839A1 (en) 2013-10-02 2015-04-02 General Electric Company Methods and systems for detection of target and applications thereof
WO2019183334A1 (en) 2018-03-21 2019-09-26 Waters Technologies Corporation Non-antibody high-affinity-based sample preparation, sorbents, devices and methods

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000219698A (ja) * 1999-01-28 2000-08-08 Jsr Corp 物質分離材料、物質分離システムおよび物質分離方法
JP2000344834A (ja) * 1999-06-09 2000-12-12 Amersham Pharmacia Biotech Kk 温度応答性を有する高分子化合物およびその製造方法
WO2002016571A1 (en) * 2000-08-21 2002-02-28 National Institute Of Advanced Industrial Science And Technology Magnetic particles having lower limit critical solution temperature
JP2002538942A (ja) * 1998-12-30 2002-11-19 フォルケ・チャーネルド 液体−液体分配を使用する分離方法
WO2004082801A1 (en) * 2003-03-20 2004-09-30 Amersham Biosciences Ab Use of ph-responsive polymers

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5093254A (en) 1990-01-23 1992-03-03 The United States Of America, As Represented By The Secretary Of Commerce Aqueous two-phase protein extraction
WO1997005480A1 (en) 1995-07-27 1997-02-13 Massachusetts Institute Of Technology Separation and/or concentration of an analyte from a mixture using a two-phase aqueous micellar system
US5907035A (en) 1996-05-23 1999-05-25 Baxter Biotech Technology Sarl Aqueous two-phase metal affinity partitioning protein purification system
US6641735B1 (en) * 2000-03-23 2003-11-04 Japan Chemical Innovation Institute Separatory material with the use of stimulus-responsive polymer and separation method by using the separatory material
EP1163260B1 (en) 1999-03-25 2009-05-20 Valtion Teknillinen Tutkimuskeskus Process for partitioning of proteins
SE9904803D0 (sv) 1999-12-27 1999-12-27 Amersham Pharm Biotech Ab Method for the isolation of hydrophobic proteins

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002538942A (ja) * 1998-12-30 2002-11-19 フォルケ・チャーネルド 液体−液体分配を使用する分離方法
JP2000219698A (ja) * 1999-01-28 2000-08-08 Jsr Corp 物質分離材料、物質分離システムおよび物質分離方法
JP2000344834A (ja) * 1999-06-09 2000-12-12 Amersham Pharmacia Biotech Kk 温度応答性を有する高分子化合物およびその製造方法
WO2002016571A1 (en) * 2000-08-21 2002-02-28 National Institute Of Advanced Industrial Science And Technology Magnetic particles having lower limit critical solution temperature
WO2004082801A1 (en) * 2003-03-20 2004-09-30 Amersham Biosciences Ab Use of ph-responsive polymers

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011106857A (ja) * 2009-11-13 2011-06-02 Toppan Forms Co Ltd 化学物質の分離キット及び分離方法
JP2011179848A (ja) * 2010-02-26 2011-09-15 Toppan Forms Co Ltd 化学物質の分離キット及び分離方法
JP2015052613A (ja) * 2010-08-27 2015-03-19 インターベット インターナショナル ベー. フェー. ワクチン製剤についての効力試験
JP2014161833A (ja) * 2013-02-27 2014-09-08 Mitsubishi Chemicals Corp タンパク質用アフィニティ分離剤

Also Published As

Publication number Publication date
AU2006327328B2 (en) 2011-08-04
US8263343B2 (en) 2012-09-11
US20080293926A1 (en) 2008-11-27
AU2006327328A1 (en) 2007-06-28
EP1976609A1 (en) 2008-10-08
WO2007073311A1 (en) 2007-06-28
EP1976609A4 (en) 2011-01-19
CA2632328A1 (en) 2007-06-28

Similar Documents

Publication Publication Date Title
US8263343B2 (en) Preparation of biomolecules
Andaç et al. Affinity based and molecularly imprinted cryogels: Applications in biomacromolecule purification
KR101901830B1 (ko) 제한된 공수화 크로마토그래피를 통한 생물학적 산물의 정제
EP2958931B9 (en) Materials and methods for removing endotoxins from protein preparations
JP5917417B2 (ja) 抗体の選択的強化
EP2961761B1 (en) Protein purification in the presence of nonionic organic polymers at elevated conductivity
CN105008383A (zh) 在非离子有机聚合物和正电性表面存在下的蛋白质纯化
JP6320429B2 (ja) 負帯電粒子を用いるウイルス調製物のクロマトグラフィー精製
WO2011034115A1 (ja) アビジンとビオチン誘導体の解離方法及び解離剤
JP7068316B2 (ja) 巨大分子の精製のための高分子メッシュの利用
KR20150113027A (ko) 티오-헤테로시클릭 양이온들로 처리에 의한 단백질 제제 내의 응집체 레벨 감소를 위한 방법
CN104470606B (zh) 用带负电荷颗粒对多核苷酸的色谱纯化
Bedade et al. Downstream processing of biotechnology products
Savina et al. Smart polymers for bioseparation and other biotechnological applications
Viglio et al. Current LC methods for the separation and analysis of peptides and proteins
US20060105325A1 (en) Adsorbent with enhanced protein binding capacity and selectivity
Nath et al. Emerging purification and isolation
Lopes et al. Lipopolysaccharides: Methods of Quantification and Removal from Biotechnological Products
Creek Sample preparation
Zorko 9 Purification and
Zorko Purification and Characterization of Proteins
HK1175185A (en) Selective enrichment of antibodies

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20091201

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20091201

RD02 Notification of acceptance of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7422

Effective date: 20091201

RD04 Notification of resignation of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7424

Effective date: 20091201

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20101117

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20111014

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20111101

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20120131

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20120619

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20120919

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20130212

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20130827