JP2009519936A5 - - Google Patents
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- Publication number
- JP2009519936A5 JP2009519936A5 JP2008545781A JP2008545781A JP2009519936A5 JP 2009519936 A5 JP2009519936 A5 JP 2009519936A5 JP 2008545781 A JP2008545781 A JP 2008545781A JP 2008545781 A JP2008545781 A JP 2008545781A JP 2009519936 A5 JP2009519936 A5 JP 2009519936A5
- Authority
- JP
- Japan
- Prior art keywords
- weight
- composition
- formulation
- polysorbate
- glycerin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 claims 96
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims 50
- 238000009472 formulation Methods 0.000 claims 34
- 235000011187 glycerol Nutrition 0.000 claims 25
- 239000000244 polyoxyethylene sorbitan monooleate Substances 0.000 claims 25
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 claims 25
- 229920000053 polysorbate 80 Polymers 0.000 claims 25
- 229940068968 polysorbate 80 Drugs 0.000 claims 25
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 24
- ZFMITUMMTDLWHR-UHFFFAOYSA-N Minoxidil Chemical compound NC1=[N+]([O-])C(N)=CC(N2CCCCC2)=N1 ZFMITUMMTDLWHR-UHFFFAOYSA-N 0.000 claims 20
- 229960003632 minoxidil Drugs 0.000 claims 20
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 18
- LXCFILQKKLGQFO-UHFFFAOYSA-N methylparaben Chemical compound COC(=O)C1=CC=C(O)C=C1 LXCFILQKKLGQFO-UHFFFAOYSA-N 0.000 claims 16
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 claims 14
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims 13
- YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 claims 12
- 229940076810 beta sitosterol Drugs 0.000 claims 12
- 229950005143 sitosterol Drugs 0.000 claims 12
- SNPLKNRPJHDVJA-ZETCQYMHSA-N D-panthenol Chemical compound OCC(C)(C)[C@@H](O)C(=O)NCCCO SNPLKNRPJHDVJA-ZETCQYMHSA-N 0.000 claims 11
- LGJMUZUPVCAVPU-UHFFFAOYSA-N beta-Sitostanol Natural products C1CC2CC(O)CCC2(C)C2C1C1CCC(C(C)CCC(CC)C(C)C)C1(C)CC2 LGJMUZUPVCAVPU-UHFFFAOYSA-N 0.000 claims 11
- NJKOMDUNNDKEAI-UHFFFAOYSA-N beta-sitosterol Natural products CCC(CCC(C)C1CCC2(C)C3CC=C4CC(O)CCC4C3CCC12C)C(C)C NJKOMDUNNDKEAI-UHFFFAOYSA-N 0.000 claims 11
- 229940101267 panthenol Drugs 0.000 claims 11
- 235000020957 pantothenol Nutrition 0.000 claims 11
- 239000011619 pantothenol Substances 0.000 claims 11
- KZJWDPNRJALLNS-VJSFXXLFSA-N sitosterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CC[C@@H](CC)C(C)C)[C@@]1(C)CC2 KZJWDPNRJALLNS-VJSFXXLFSA-N 0.000 claims 11
- WSDISUOETYTPRL-UHFFFAOYSA-N dmdm hydantoin Chemical compound CC1(C)N(CO)C(=O)N(CO)C1=O WSDISUOETYTPRL-UHFFFAOYSA-N 0.000 claims 9
- 230000003779 hair growth Effects 0.000 claims 9
- 235000010270 methyl p-hydroxybenzoate Nutrition 0.000 claims 8
- 239000004292 methyl p-hydroxybenzoate Substances 0.000 claims 8
- 229960002216 methylparaben Drugs 0.000 claims 8
- 239000011607 retinol Substances 0.000 claims 8
- 229960003471 retinol Drugs 0.000 claims 8
- FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 claims 7
- 235000020944 retinol Nutrition 0.000 claims 7
- VYGQUTWHTHXGQB-FFHKNEKCSA-N Retinol Palmitate Chemical compound CCCCCCCCCCCCCCCC(=O)OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C VYGQUTWHTHXGQB-FFHKNEKCSA-N 0.000 claims 6
- 239000004480 active ingredient Substances 0.000 claims 6
- 229960002685 biotin Drugs 0.000 claims 6
- 235000020958 biotin Nutrition 0.000 claims 6
- 239000011616 biotin Substances 0.000 claims 6
- LEVWYRKDKASIDU-QWWZWVQMSA-N D-cystine Chemical compound OC(=O)[C@H](N)CSSC[C@@H](N)C(O)=O LEVWYRKDKASIDU-QWWZWVQMSA-N 0.000 claims 5
- 229960003067 cystine Drugs 0.000 claims 5
- 235000013399 edible fruits Nutrition 0.000 claims 5
- 239000004615 ingredient Substances 0.000 claims 5
- 238000000034 method Methods 0.000 claims 5
- 241000880493 Leptailurus serval Species 0.000 claims 4
- ILVGMCVCQBJPSH-WDSKDSINSA-N Ser-Val Chemical compound CC(C)[C@@H](C(O)=O)NC(=O)[C@@H](N)CO ILVGMCVCQBJPSH-WDSKDSINSA-N 0.000 claims 4
- 229920001213 Polysorbate 20 Polymers 0.000 claims 3
- 239000008365 aqueous carrier Substances 0.000 claims 3
- XUJNEKJLAYXESH-UHFFFAOYSA-N cysteine Natural products SCC(N)C(O)=O XUJNEKJLAYXESH-UHFFFAOYSA-N 0.000 claims 3
- 235000018417 cysteine Nutrition 0.000 claims 3
- 239000000256 polyoxyethylene sorbitan monolaurate Substances 0.000 claims 3
- 235000010486 polyoxyethylene sorbitan monolaurate Nutrition 0.000 claims 3
- 229940068977 polysorbate 20 Drugs 0.000 claims 3
- -1 retinoid compounds Chemical class 0.000 claims 3
- 229940108325 retinyl palmitate Drugs 0.000 claims 3
- 235000019172 retinyl palmitate Nutrition 0.000 claims 3
- 239000011769 retinyl palmitate Substances 0.000 claims 3
- 239000002904 solvent Substances 0.000 claims 3
- 230000009885 systemic effect Effects 0.000 claims 3
- 238000011200 topical administration Methods 0.000 claims 3
- XUJNEKJLAYXESH-REOHCLBHSA-N L-Cysteine Chemical compound SC[C@H](N)C(O)=O XUJNEKJLAYXESH-REOHCLBHSA-N 0.000 claims 2
- 230000001476 alcoholic effect Effects 0.000 claims 2
- 230000008020 evaporation Effects 0.000 claims 2
- 238000001704 evaporation Methods 0.000 claims 2
- 229960005150 glycerol Drugs 0.000 claims 2
- 238000013508 migration Methods 0.000 claims 2
- 230000005012 migration Effects 0.000 claims 2
- 239000003755 preservative agent Substances 0.000 claims 2
- 230000002335 preservative effect Effects 0.000 claims 2
- ALDITMKAAPLVJK-UHFFFAOYSA-N prop-1-ene;hydrate Chemical group O.CC=C ALDITMKAAPLVJK-UHFFFAOYSA-N 0.000 claims 2
- 230000000699 topical effect Effects 0.000 claims 2
- 235000005318 Serenoa repens Nutrition 0.000 claims 1
- 240000006661 Serenoa repens Species 0.000 claims 1
- 239000013543 active substance Substances 0.000 claims 1
- 239000000654 additive Substances 0.000 claims 1
- 230000000996 additive effect Effects 0.000 claims 1
- 235000008429 bread Nutrition 0.000 claims 1
- 229960002433 cysteine Drugs 0.000 claims 1
- 150000002334 glycols Chemical class 0.000 claims 1
- 230000035515 penetration Effects 0.000 claims 1
- 210000004761 scalp Anatomy 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11/305,647 US8147815B2 (en) | 2005-12-16 | 2005-12-16 | Topical administration carrier composition and therapeutic formulations comprising same |
| PCT/US2006/047615 WO2007078796A2 (en) | 2005-12-16 | 2006-12-13 | Topical administration carrier composition and therapeutic formulations comprising same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009519936A JP2009519936A (ja) | 2009-05-21 |
| JP2009519936A5 true JP2009519936A5 (https=) | 2010-01-14 |
Family
ID=38163238
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008545781A Pending JP2009519936A (ja) | 2005-12-16 | 2006-12-13 | 局所投与用担体組成物およびそれを含む治療用配合物 |
Country Status (7)
| Country | Link |
|---|---|
| US (4) | US8147815B2 (https=) |
| EP (1) | EP1971308B1 (https=) |
| JP (1) | JP2009519936A (https=) |
| KR (1) | KR100836002B1 (https=) |
| CN (1) | CN101365411B (https=) |
| RU (1) | RU2008129090A (https=) |
| WO (2) | WO2007070069A1 (https=) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8147815B2 (en) * | 2005-12-16 | 2012-04-03 | Celmatrix Corporation | Topical administration carrier composition and therapeutic formulations comprising same |
| US20080206156A1 (en) * | 2007-02-22 | 2008-08-28 | Cronk Peter J | Continuous spray scalp therapy and dispensing systems for same |
| US8021649B2 (en) | 2007-02-22 | 2011-09-20 | Cronk Peter J | Continuous spray scalp therapy and dispensing systems for same |
| KR100878198B1 (ko) * | 2008-05-06 | 2009-01-13 | 현대약품 주식회사 | 미녹시딜을 포함하는 겔 조성물 |
| US20110112125A1 (en) * | 2009-11-09 | 2011-05-12 | Tritech Biopharmaceuticals Co., Ltd. | Novel hair growth composition |
| US9271917B2 (en) | 2010-01-29 | 2016-03-01 | Nyangenya Maniga | Method and apparatus for delivery of a measured dosage of a non-aerosol, non-spray foam composition of minoxidil |
| US20110189114A1 (en) * | 2010-01-29 | 2011-08-04 | Nyangenya Maniga | minoxidil composition and non-aerosol, non-spray foam method of delivery therefor |
| WO2014122436A1 (en) * | 2013-02-07 | 2014-08-14 | Cipla House | Topical pharmaceutical compositions comprising minoxidil |
| US8642097B1 (en) | 2013-03-19 | 2014-02-04 | Nyangenya Maniga | Natural product energy drink and method of use thereof |
| US20150174254A1 (en) * | 2013-12-23 | 2015-06-25 | Mcneil-Ppc, Inc. | Topical gel compositions including polycaprolactone polymer and methods for enhancing the topical application of a benefit agent |
| US10213479B2 (en) | 2014-01-23 | 2019-02-26 | The University Of Kansas | Compounds and methods for increasing hair growth |
| US20160000858A1 (en) * | 2014-07-07 | 2016-01-07 | Gojo Industries, Inc. | Compositions and methods for mitigating skin irritation and enhancing skin barrier function |
| GB201412976D0 (en) * | 2014-07-22 | 2014-09-03 | Perachem Ltd | Hair treatments |
| EP3209275A4 (en) * | 2014-10-24 | 2018-04-11 | Beautopia LLC | Combined hair loss inhibition treatment |
| US20160175224A1 (en) * | 2014-12-19 | 2016-06-23 | Johnson & Johnson Consumer Companies, Inc. | Antiperspirant composition |
| JP6528194B2 (ja) * | 2015-02-06 | 2019-06-12 | ダイヤ製薬株式会社 | ミノキシジル含有外用液剤および外用液剤の製造方法 |
| CN104800150A (zh) * | 2015-05-13 | 2015-07-29 | 常州市第四制药厂有限公司 | 一种米诺地尔乳膏剂及制备方法 |
| GB2554000A (en) * | 2015-05-18 | 2018-03-21 | Perry Thrower Angelo | Hair regrowth treatment and growth stimulant |
| US9962444B2 (en) * | 2016-09-27 | 2018-05-08 | Shane Malek | Pharmacokinetically extended action topical hair growth formulation, and administration method |
| EP3558255B1 (en) | 2016-12-21 | 2021-10-13 | Unilever IP Holdings B.V. | Topical skin lightening additive and composition with amino acids and nicotinamide compounds |
| US11337908B2 (en) | 2016-12-21 | 2022-05-24 | Conopco, Inc. | Personal care compositions with cystine |
| US11260005B2 (en) | 2016-12-21 | 2022-03-01 | Conopco, Inc. | Personal care compositions with glutathione precursor comprising 4-substituted resorcinols and amino acids |
| JP7084924B2 (ja) | 2016-12-21 | 2022-06-15 | ユニリーバー・アイピー・ホールディングス・ベスローテン・ヴェンノーツハップ | 難溶性化合物を含むパーソナルケア組成物 |
| US20190275354A1 (en) * | 2017-08-15 | 2019-09-12 | Medical Hair Restoration, PLLC | Methods, compositions and apparatuses for treating hair loss |
| CN112165927B (zh) | 2018-05-23 | 2024-01-30 | 联合利华知识产权控股有限公司 | 纳米乳液及其制备方法 |
| JP2021525573A (ja) | 2018-05-30 | 2021-09-27 | フォリカ, インコーポレーテッドFollica, Inc. | 発毛促進のための方法 |
| JP7518466B2 (ja) * | 2019-04-10 | 2024-07-18 | 大正製薬株式会社 | 外用医薬組成物 |
| US12539302B2 (en) | 2019-08-07 | 2026-02-03 | Aneira Pharma, Inc. | Methods and compositions for the treatment of hair loss |
| EP4331683A3 (en) | 2019-08-07 | 2024-08-07 | Aneira Pharma, Inc. | Methods and compositions for the treatment of hair loss |
| FR3104961B1 (fr) * | 2019-12-20 | 2022-03-25 | Oreal | Composition cosmetique comprenant au moins un polyol comportant au moins trois fonctions hydroxy et au moins un ester de sorbitan polyoxyethylene |
| US20230293398A1 (en) * | 2020-09-07 | 2023-09-21 | Amorepacific Corporation | Sanitizer composition in emulsion formulation |
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-
2005
- 2005-12-16 US US11/305,647 patent/US8147815B2/en not_active Expired - Fee Related
-
2006
- 2006-02-21 WO PCT/US2006/006958 patent/WO2007070069A1/en not_active Ceased
- 2006-12-13 JP JP2008545781A patent/JP2009519936A/ja active Pending
- 2006-12-13 EP EP06845368.7A patent/EP1971308B1/en not_active Not-in-force
- 2006-12-13 CN CN2006800512906A patent/CN101365411B/zh not_active Expired - Fee Related
- 2006-12-13 RU RU2008129090/15A patent/RU2008129090A/ru not_active Application Discontinuation
- 2006-12-13 WO PCT/US2006/047615 patent/WO2007078796A2/en not_active Ceased
- 2006-12-13 US US11/610,322 patent/US7749489B2/en not_active Expired - Lifetime
- 2006-12-15 KR KR1020060128936A patent/KR100836002B1/ko not_active Expired - Fee Related
-
2010
- 2010-07-06 US US12/831,241 patent/US8119111B2/en not_active Expired - Fee Related
-
2012
- 2012-02-21 US US13/401,530 patent/US8444960B2/en not_active Expired - Fee Related
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