JP2009516155A - チアゾリジンジオン反応性バイオマーカーを用いる治療物質の同定法 - Google Patents

チアゾリジンジオン反応性バイオマーカーを用いる治療物質の同定法 Download PDF

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JP2009516155A
JP2009516155A JP2008532651A JP2008532651A JP2009516155A JP 2009516155 A JP2009516155 A JP 2009516155A JP 2008532651 A JP2008532651 A JP 2008532651A JP 2008532651 A JP2008532651 A JP 2008532651A JP 2009516155 A JP2009516155 A JP 2009516155A
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protein
peptide
substance
thiazolidinedione
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JP2009516155A5 (enExample
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ペトラ・ブッデ
ホルスト・ローゼ
ハンス−ディーター・ツッフト
アネッテ・アッペル
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Digilab Inc
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Digilab Inc
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
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    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
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    • G01—MEASURING; TESTING
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    • G01N2800/00—Detection or diagnosis of diseases
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    • G01N2800/00—Detection or diagnosis of diseases
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    • G01N2800/044—Hyperlipemia or hypolipemia, e.g. dyslipidaemia, obesity
    • G—PHYSICS
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  • Heart & Thoracic Surgery (AREA)
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  • Proteomics, Peptides & Aminoacids (AREA)
  • Pain & Pain Management (AREA)
  • Vascular Medicine (AREA)
  • Neurosurgery (AREA)
JP2008532651A 2005-09-30 2006-09-26 チアゾリジンジオン反応性バイオマーカーを用いる治療物質の同定法 Withdrawn JP2009516155A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05021530A EP1876448A1 (en) 2005-09-30 2005-09-30 Method and analytical reagents for identifying therapeutics using biomarkers responsive to thiazolidinediones.
PCT/EP2006/009324 WO2007039184A2 (en) 2005-09-30 2006-09-26 Method and analytical reagents for identifying therapeutics using biomarkers responsive to thiazolidinediones

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JP2009516155A true JP2009516155A (ja) 2009-04-16
JP2009516155A5 JP2009516155A5 (enExample) 2009-11-12

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JP2008532651A Withdrawn JP2009516155A (ja) 2005-09-30 2006-09-26 チアゾリジンジオン反応性バイオマーカーを用いる治療物質の同定法

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EP (2) EP1876448A1 (enExample)
JP (1) JP2009516155A (enExample)
CA (1) CA2623685A1 (enExample)
WO (1) WO2007039184A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011508218A (ja) * 2007-12-19 2011-03-10 イーライ リリー アンド カンパニー 肥満症の薬物療法に対する反応性を予測するための方法

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8673848B2 (en) 2012-01-27 2014-03-18 Novartis Ag Synthetic apelin mimetics for the treatment of heart failure
KR20100053607A (ko) 2007-08-03 2010-05-20 패시트 바이오테크 코포레이션 항-ｔｗｅａｋ 수용체 항체의 치료 용도
US10519504B2 (en) * 2009-05-11 2019-12-31 Berg Llc Methods for treatment of oncological disorders using epimetabolic shifters, multidimensional intracellular molecules, or environmental influencers
EP2694463B8 (en) 2011-04-04 2019-10-09 Berg LLC Treating central nervous system tumors with coenzyme q10
UY35144A (es) 2012-11-20 2014-06-30 Novartis Ag Miméticos lineales sintéticos de apelina para el tratamiento de insuficiencia cardiaca
US8921307B2 (en) 2012-11-20 2014-12-30 Novartis Ag Synthetic linear apelin mimetics for the treatment of heart failure
EA032775B1 (ru) 2013-04-08 2019-07-31 Берг Ллк Способы лечения злокачественной опухоли с использованием комбинированной терапии с коферментом q10
SG11201600211XA (en) 2013-07-25 2016-02-26 Novartis Ag Cyclic polypeptides for the treatment of heart failure
TW201518323A (zh) 2013-07-25 2015-05-16 Novartis Ag 合成ａｐｅｌｉｎ多肽之生物結合物
WO2015035094A1 (en) 2013-09-04 2015-03-12 Berg Llc Methods of treatment of cancer by continuous infusion of coenzyme q10
WO2017087576A1 (en) 2015-11-16 2017-05-26 Berg Llc Methods of treatment of temozolomide-resistant glioma using coenzyme q10

Family Cites Families (6)

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Publication number Priority date Publication date Assignee Title
DK1015477T3 (da) * 1997-05-30 2011-02-07 Human Genome Sciences Inc 32 humane sekreterede proteiner
US7495086B2 (en) * 1999-12-20 2009-02-24 Immunex Corporation TWEAK receptor
AU782067B2 (en) * 1999-12-20 2005-06-30 Immunex Corporation TWEAK receptor
EP1287030A1 (en) * 2000-06-08 2003-03-05 Metcon Medicin AB Insulin regulated substance (irs-2) induced by pioglitazone, assay and use thereof
US20050084872A1 (en) * 2003-01-24 2005-04-21 Lum Pek Y. Methods for determining whether an agent possesses a defined biological activity
EP1566636A1 (en) * 2004-02-23 2005-08-24 AXARON Bioscience AG Use of Tweak modulators and inhibitors for the treatment of neurological conditions

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011508218A (ja) * 2007-12-19 2011-03-10 イーライ リリー アンド カンパニー 肥満症の薬物療法に対する反応性を予測するための方法

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WO2007039184A2 (en) 2007-04-12
WO2007039184A3 (en) 2007-07-12
EP1929309A2 (en) 2008-06-11
CA2623685A1 (en) 2007-04-12
EP1876448A1 (en) 2008-01-09

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