JP2009515183A - 新たなタンパク質アイソフォーム及びその使用 - Google Patents

新たなタンパク質アイソフォーム及びその使用 Download PDF

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Publication number
JP2009515183A
JP2009515183A JP2008539508A JP2008539508A JP2009515183A JP 2009515183 A JP2009515183 A JP 2009515183A JP 2008539508 A JP2008539508 A JP 2008539508A JP 2008539508 A JP2008539508 A JP 2008539508A JP 2009515183 A JP2009515183 A JP 2009515183A
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protein isoform
protein
isoform
antibody
related polypeptide
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JP2008539508A
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Japanese (ja)
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JP2009515183A5 (enExample
Inventor
ロフルフフ クフリスチアン
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オクフォルド ゲノメ スシエンセス (ユーケー) エルティーディー
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Priority claimed from GB0522667A external-priority patent/GB0522667D0/en
Application filed by オクフォルド ゲノメ スシエンセス (ユーケー) エルティーディー filed Critical オクフォルド ゲノメ スシエンセス (ユーケー) エルティーディー
Publication of JP2009515183A publication Critical patent/JP2009515183A/ja
Publication of JP2009515183A5 publication Critical patent/JP2009515183A5/ja
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00Screening for compounds of potential therapeutic value
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/28Neurological disorders

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Psychiatry (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Psychology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2008539508A 2005-11-08 2006-11-08 新たなタンパク質アイソフォーム及びその使用 Pending JP2009515183A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0522667A GB0522667D0 (en) 2005-11-08 2005-11-08 New protein isoforms and uses thereof
US73479905P 2005-11-09 2005-11-09
PCT/GB2006/050375 WO2007072070A1 (en) 2005-11-08 2006-11-08 New protein isoforms and uses thereof

Publications (2)

Publication Number Publication Date
JP2009515183A true JP2009515183A (ja) 2009-04-09
JP2009515183A5 JP2009515183A5 (enExample) 2009-12-24

Family

ID=37845158

Family Applications (1)

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JP2008539508A Pending JP2009515183A (ja) 2005-11-08 2006-11-08 新たなタンパク質アイソフォーム及びその使用

Country Status (4)

Country Link
US (1) US20090311180A1 (enExample)
EP (1) EP1999150A1 (enExample)
JP (1) JP2009515183A (enExample)
WO (1) WO2007072070A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011033547A (ja) * 2009-08-04 2011-02-17 Hoyu Co Ltd 2次元電気泳動方法

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010005387A1 (en) * 2008-07-10 2010-01-14 Astrazeneca Ab New method and biomarkers for the diagnosis of multiple sclerosis
DE102008054716A1 (de) * 2008-12-16 2010-06-17 Evonik Degussa Gmbh Inprozesskontrolle in einem Verfahren zur Herstellung von EPO
CA2754072C (en) 2009-03-02 2019-01-15 Massachusetts Institute Of Technology Methods and products for in vivo enzyme profiling
US8778307B2 (en) 2009-06-05 2014-07-15 University Of Maryland, College Park Targeted carriers for drug delivery across the gastrointestinal epithelium
CA3214092A1 (en) 2011-03-15 2012-09-20 Massachusetts Institute Of Technology Multiplexed detection with isotope-coded reporters
US20140037656A1 (en) * 2011-04-30 2014-02-06 Mitchell S. Felder Treatment for Tauopathies
EP2714096B1 (en) 2011-06-03 2018-02-28 Ophidion Inc. Compositions and methods for transport across the blood brain barrier
US9244946B2 (en) 2012-11-26 2016-01-26 International Business Machines Corporation Data mining shape based data
JP6847660B2 (ja) 2013-06-07 2021-03-24 マサチューセッツ インスティテュート オブ テクノロジー リガンドをコードする合成バイオマーカーのアフィニティベースの検出
US11448643B2 (en) 2016-04-08 2022-09-20 Massachusetts Institute Of Technology Methods to specifically profile protease activity at lymph nodes
WO2017193070A1 (en) 2016-05-05 2017-11-09 Massachusetts Institute Of Technology Methods and uses for remotely triggered protease activity measurements
AU2018248327B2 (en) 2017-04-07 2024-10-10 Massachusetts Institute Of Technology Methods to spatially profile protease activity in tissue and sections
WO2020068920A2 (en) 2018-09-25 2020-04-02 Massachusetts Institute Of Technology Lung protease nanosensors and uses thereof
EP3911753A1 (en) 2019-01-17 2021-11-24 Massachusetts Institute of Technology Sensors for detecting and imaging of cancer metastasis
RU2734649C1 (ru) * 2020-02-11 2020-10-21 Федеральное государственное бюджетное учреждение науки институт биоорганической химии им. академиков М.М. Шемякина и Ю.А. Овчинникова Российской академии наук (ИБХ РАН) Пептид, обладающий активностью белка lynx1 (варианты), фармацевтическая композиция для лечения тревожных расстройств и депрессии или коррекции когнитивных нарушений при нейродегенеративных заболеваниях, содержащая указанный пептид, и способ лечения и коррекции указанных нарушений
WO2020167167A2 (ru) * 2019-02-13 2020-08-20 Федеральное государственное бюджетное учреждение науки институт биоорганической химии им. академиков М.М. Шемякина и Ю.А. Овчинникова Российской академии наук (ИБХ РАН) Пептид, обладающий активностью белка lynx1, (варианты), фармацевтическая композиция для лечения тревожных расстройств и депрессии или коррекции когнитивных нарушений при нейродегенеративных заболеваниях, содержащая указанный пептид, и способ лечения и коррекции указанных нарушений

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003284574A (ja) * 2001-10-03 2003-10-07 Pfizer Prod Inc 核酸分子、ポリペプチド、ならびにアルツハイマー病の診断および処置を含むそれらの使用
WO2003083472A1 (en) * 2002-03-29 2003-10-09 Wako Pure Chemical Industries, Ltd. Method of judging risk of peiodontal disease

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1114153A2 (en) * 1998-09-18 2001-07-11 The Rockefeller University Lynx, a novel family of receptor ligands in the central nervous system, corresponding nucleic acids and proteins and uses therof
US20020156009A1 (en) * 2000-11-02 2002-10-24 Dennis Ballinger Novel interleukin - 1 Hy2 materials and methods
US20060078890A1 (en) * 2004-10-08 2006-04-13 Ole Isacson Methods for identifying parkinson's disease therapeutics

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003284574A (ja) * 2001-10-03 2003-10-07 Pfizer Prod Inc 核酸分子、ポリペプチド、ならびにアルツハイマー病の診断および処置を含むそれらの使用
WO2003083472A1 (en) * 2002-03-29 2003-10-09 Wako Pure Chemical Industries, Ltd. Method of judging risk of peiodontal disease

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011033547A (ja) * 2009-08-04 2011-02-17 Hoyu Co Ltd 2次元電気泳動方法

Also Published As

Publication number Publication date
US20090311180A1 (en) 2009-12-17
EP1999150A1 (en) 2008-12-10
WO2007072070A1 (en) 2007-06-28

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