WO2003083472A1 - Method of judging risk of peiodontal disease - Google Patents

Method of judging risk of peiodontal disease Download PDF

Info

Publication number
WO2003083472A1
WO2003083472A1 PCT/JP2003/003269 JP0303269W WO03083472A1 WO 2003083472 A1 WO2003083472 A1 WO 2003083472A1 JP 0303269 W JP0303269 W JP 0303269W WO 03083472 A1 WO03083472 A1 WO 03083472A1
Authority
WO
WIPO (PCT)
Prior art keywords
judging risk
protein
judging
risk
peiodontal
Prior art date
Application number
PCT/JP2003/003269
Other languages
French (fr)
Japanese (ja)
Inventor
Kunio Takano
Original Assignee
Wako Pure Chemical Industries, Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wako Pure Chemical Industries, Ltd. filed Critical Wako Pure Chemical Industries, Ltd.
Priority to JP2003580855A priority Critical patent/JP4288180B2/en
Priority to AU2003220903A priority patent/AU2003220903A1/en
Publication of WO2003083472A1 publication Critical patent/WO2003083472A1/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes

Abstract

(1) A protein occurring in human saliva and being fractionated into a 35 kDa fraction by sodium dodecyl sulfate polyacrylamide gel electrophoresis, or a protein containing the amino acid sequence represented by SEQ ID NO:2; (2) a method of judging risk of periodontal disease characterized by comprising examining the presence/absence of the above protein in the saliva of a subject and judging risk of periodontal diseases based on the results; (3) a reagent for judging risk of periodontal disease which contains the above protein as a standard; and (4) a drug inhibiting the formation of dental calculus from dental plaque and an alveolar bone absorption inhibitor.
PCT/JP2003/003269 2002-03-29 2003-03-18 Method of judging risk of peiodontal disease WO2003083472A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2003580855A JP4288180B2 (en) 2002-03-29 2003-03-18 Method for determining periodontal disease risk
AU2003220903A AU2003220903A1 (en) 2002-03-29 2003-03-18 Method of judging risk of peiodontal disease

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2002094010 2002-03-29
JP2002-094010 2002-03-29

Publications (1)

Publication Number Publication Date
WO2003083472A1 true WO2003083472A1 (en) 2003-10-09

Family

ID=28671774

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2003/003269 WO2003083472A1 (en) 2002-03-29 2003-03-18 Method of judging risk of peiodontal disease

Country Status (3)

Country Link
JP (1) JP4288180B2 (en)
AU (1) AU2003220903A1 (en)
WO (1) WO2003083472A1 (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006019179A1 (en) * 2004-08-17 2006-02-23 Japan Science And Technology Agency Method of labeling with use of rare earth fluorescent complex and relevant method of analysis and detection
JP2009515183A (en) * 2005-11-08 2009-04-09 オクフォルド ゲノメ スシエンセス （ユーケー） エルティーディー New protein isoforms and uses thereof
JP2011173867A (en) * 2010-01-26 2011-09-08 Sun Medical Co Ltd Resin-based composition containing protein

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6336800A (en) * 1986-07-29 1988-02-17 Sunstar Inc Agent for examining periodontal disease
JPH08501629A (en) * 1992-09-18 1996-02-20 ザ、プロクター、エンド、ギャンブル、カンパニー Method and kit for assessing the risk of developing periodontitis

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6336800A (en) * 1986-07-29 1988-02-17 Sunstar Inc Agent for examining periodontal disease
JPH08501629A (en) * 1992-09-18 1996-02-20 ザ、プロクター、エンド、ギャンブル、カンパニー Method and kit for assessing the risk of developing periodontitis

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006019179A1 (en) * 2004-08-17 2006-02-23 Japan Science And Technology Agency Method of labeling with use of rare earth fluorescent complex and relevant method of analysis and detection
JP2009515183A (en) * 2005-11-08 2009-04-09 オクフォルド ゲノメ スシエンセス （ユーケー） エルティーディー New protein isoforms and uses thereof
JP2011173867A (en) * 2010-01-26 2011-09-08 Sun Medical Co Ltd Resin-based composition containing protein
JP2014240416A (en) * 2010-01-26 2014-12-25 サンメディカル株式会社 Method for producing protein-containing resin compositions

Also Published As

Publication number Publication date
JP4288180B2 (en) 2009-07-01
JPWO2003083472A1 (en) 2005-08-11
AU2003220903A1 (en) 2003-10-13

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